Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where Centre for Targeted Protein Degradation is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
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Profiles
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Casement, Ryan
- Centre for Targeted Protein Degradation - Postdoctoral Research Assistant
Person: Research
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Green PROTACs – bringing targeted protein degradation to plants for rapid research progress
Ciulli, A. (Investigator) & Hemsley, P. (Investigator)
Biotechnology and Biological Sciences Research Council
1/10/25 → 30/09/26
Project: Research
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Small Molecule Assisted Protein-Protein Interaction Mapping via Peroxidase Activity (MapPEX)
Ciulli, A. (Investigator)
1/07/24 → 30/06/26
Project: Research
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Unlocking Mitophagy Activation With Small Molecule Targeted Protein Stabilisers - Fellowship (Joint with UCL/Francis Crick Institute)
Farnaby, W. (Investigator)
1/10/23 → 30/09/28
Project: Research
Research output
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A method for the detection and enrichment of endogenous cereblon substrates
Lloyd, H. C., Li, Y., Payne, N. C., Zhao, Z., Xu, W., Kroupova, A., Zollman, D., Long, T., Kabir, F., Chen, M., Freeman, R., Feng, E. Y., Xi, S. Y., Hsu, Y. C., Ciulli, A., Mazitschek, R. & Woo, C. M. (Lead / Corresponding author), 21 Aug 2025, In: Cell Chemical Biology. 32, 8, p. 1028-1041.e13Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
A patent review of von Hippel-Lindau (VHL)-recruiting chemical matter: E3 Ligase Ligands for PROTACs and targeted protein degradation (2019-present)
Urbina Teixidor, A., Hallatt, A., Robertson, J. & Ciulli, A. (Lead / Corresponding author), 2025, In: Expert Opinion on Therapeutic Patents. 35, 3, p. 197-238 42 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)285 Downloads (Pure) -
Branching beyond bifunctional linkers: synthesis of macrocyclic and trivalent PROTACs
Cao, Y., Harris, A. L. & Ciulli, A. (Lead / Corresponding author), 11 Nov 2025, (E-pub ahead of print) In: Nature Protocols. 39 p.Research output: Contribution to journal › Protocol › peer-review
Datasets
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Crystal Structure of compound 3-mediated ternary complex of KRAS G12V C118S GDP with pVHL:ElonginC:ElonginB
Zollman, D. (Creator), Karolak, N. (Creator) & Ciulli, A. (Creator), Protein Data Bank (PDB), 26 Nov 2025
DOI: 10.2210/pdb9rk8/pdb
Dataset
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Crystal Structure of ACBI4-mediated ternary complex of KRAS G12D C118S GDP with pVHL:ElonginC:ElonginB
Karolak, N. (Creator) & Ciulli, A. (Creator), Protein Data Bank (PDB), 12 Nov 2025
DOI: 10.2210/pdb9rkc/pdb
Dataset
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Crystal Structure of compound 3-mediated ternary complex of KRAS G12R GCP with pVHL:ElonginC:ElonginB
Wijaya, A. (Creator), Karolak, N. (Creator) & Ciulli, A. (Creator), Protein Data Bank (PDB), 12 Nov 2025
DOI: 10.2210/pdb9rkj/pdb
Dataset
Prizes
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Cancer Research Horizons Further, Faster, Together Industry-Academia Award
Ciulli, A. (Recipient) & McAulay, K. (Recipient), 2024
Prize: Prize (including medals and awards)
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Industry and Academic Collaboration Award
Ciulli, A. (Recipient), Cowan, A. (Recipient), Frost, A. (Recipient), Gadakh, B. (Recipient), Khan, S. (Recipient), Kidd, G. (Recipient), McAulay, K. (Recipient), Morake, M. (Recipient), Puoti, I. (Recipient), Rutter, Z. (Recipient), Simpson, L. (Recipient), Sturbaut, M. (Recipient), Vetma, V. (Recipient), Wong, J. (Recipient), Zhang, Q. (Recipient), Zhmurov, P. (Recipient), Little, G. (Recipient), McCrory, E. (Recipient), Karolak, N. (Recipient), Djukic, S. (Recipient), Gibson, M. (Recipient) & Murdoch, N. (Recipient), 2026
Prize: Prize (including medals and awards)
Activities
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Alzheimer's Scotland and patient parents' visit to School of Life Sciences
Green, C. (Organiser), Ahmed, M. (Participant), Ashford, M. (Participant), Ciulli, A. (Participant), Farnaby, W. (Participant), Cossar, P. (Participant) & Kidd, G. (Participant)
25 Nov 2025Activity: Other activity types › Other
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RSC Tayside Summer Lecture
McAulay, K. (Organiser), Little, G. (Participant), Murdoch, N. (Participant), Westwood, M. (Participant), Law, K. (Participant) & Livingstone, C. (Participant)
10 Jun 2025Activity: Other activity types › Schools engagement
Press/Media
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Parliamentary recognition for Dundee staff and students
Ciulli, A., Martin, M., George, J., Barratt, C. & Rodriguez, A.
22/05/25
1 Media contribution
Press/Media: Other
Student theses
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Biological Characterisation of the Cellular Target Engagement and Function of SOCS2 and CISH using novel covalent inhibitor, MN714
Forrester, B. (Author), Ciulli, A. (Supervisor), Cantrell, D. (Supervisor) & Moraga Gonzalez, I. (Supervisor), 2024Student thesis: Master's Thesis › Master of Science
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Characterising a novel tandem BromoTag through development of an eGFP:mCherry dual reporter assay
Hardie, S. (Author), Ciulli, A. (Supervisor), 2025Student thesis: Master's Thesis › Master of Science
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Green PROTACs: Towards Cereblon-Mediated Degradation in Plants
Mcintosh, W. (Author), Hemsley, P. (Supervisor) & Ciulli, A. (Supervisor), 2025Student thesis: Master's Thesis › Master of Science