Computational Biology

Projects

Projects per year 2009 2024

• 7 Not started
• 7 Active
• 13 Finished

Projects per year

Search results

• Active

  Control of PolyA Site Choice by m6A RNA Modification

  Barton, G. & Simpson, G.

  Biotechnology and Biological Sciences Research Council

  1/07/21 → 30/06/24

  Project: Research

• Novel Machine Learning Techniques to Elucidate Function and Dynamics of Epigenomic Mechanisms

  Schweikert, G.

  Academy of Medical Sciences

  15/02/21 → 14/02/23

  Project: Research

• High Resolution Structure, Function and Anti-Viral Inhibition of the SARS-CoV2 E Protein Ion Channel (joint with St Andrews University and Trinity College Dublin)

  Zachariae, U.

  Biotechnology and Biological Sciences Research Council

  8/02/21 → 7/08/22

  Project: Research

• Machine Learning Methods to Re-Annotate Histone Modifications with Locus-specific Functional Classification (Future Leaders Fellowship)

  Owen-Hughes, T. & Schweikert, G.

  Medical Research Council

  1/11/20 → 31/10/24

  Project: Research

• The Jalview Resource for Biological Sequence, Structure and Function Analysis: 2019 and Beyond

  Barton, G. & Procter, J.

  Wellcome Trust

  1/01/20 → 31/12/24

  Project: Research

• Unravelling the Barley Genetic Control of the Rhizosphere Microbiota

  Barton, G., Bulgarelli, D. & Waugh, R.

  Biotechnology and Biological Sciences Research Council

  17/12/18 → 16/05/22

  Project: Research

  • Soil 100%
  • Microbiota 91%
  • Crop Production 84%
  • Plant Development 73%
  • Soils 72%

• The Dundee Resource for Sequence Analysis and Structure Prediction

  Barton, G.

  Biotechnology and Biological Sciences Research Council

  1/09/18 → 31/08/23

  Project: Research

  • SARS Virus 100%
  • angiotensin converting enzyme 2 67%
  • Sequence Alignment 41%
  • Web Services 37%
  • RNA Secondary Structure 34%
• Not started

  GPU-Based Machine Learning System For Fundamental Biological Research

  Barton, G., Gilbert, I., Lamond, A., Owen-Hughes, T., Pisliakov, A., Schweikert, G., Sknepnek, R., Swedlow, J., Weijer, K. & Zachariae, U.

  Biotechnology and Biological Sciences Research Council

  1/08/21 → 31/07/22

  Project: Research

• Sparking Impact Award

  Barton, G.

  Project: Research

• Adaptive Sequencing of Evolutionarily Distant Disease Resistance Genes Using Nanopore (Joint with University of Cambridge)

  Barton, G., Parker, M. & Simpson, G.

  Project: Research

• Transforming the Annotation of Neglected Crop Genomes (GCRF)

  Barton, G. & Simpson, G.

  Project: Research

• Developing Orphan Crops Genome Annotation (GCRF Round 2020/21)

  Barton, G. & Simpson, G.

  Project: Research

• Extension to College of Life Sciences Research Complex to Create a Centre for Translational and Interdisciplinary Research (Wolfson Award)

  Barton, G., Chaplain, M., Fairlamb, A., Ferguson, M., Gilbert, I., Hopkins, A., Lamond, A., Swedlow, J. & Wyatt, P.

  Project: Research

• Breaking the Membrane Permeability Barrier for Antimicrobials in Gram-negative Bacteria (Vacation Scholarship 2017)

  Zachariae, U.

  Project: Research

• Finished

  Diversifying Transcription Termination Function

  Barton, G. & Simpson, G.

  Biotechnology and Biological Sciences Research Council

  1/06/15 → 31/05/19

  Project: Research

  • Arabidopsis 100%
  • RNA-Seq 84%
  • RNA Sequence Analysis 65%
  • Antisense RNA 34%
  • Nanopores 34%

• The Arabidopsis Epitranscriptome (Joint with University of Nottingham)

  Barton, G. & Simpson, G.

  Biotechnology and Biological Sciences Research Council

  1/04/15 → 31/03/19

  Project: Research

  • RNA-Seq 100%
  • Arabidopsis 90%
  • RNA Sequence Analysis 78%
  • RNA 51%
  • Nanopores 41%

• The Jalview Resource for Sequence Analysis and Annotation (Bioinformatics and Biomedical Resource Fund)

  Barton, G. & Procter, J.

  Biotechnology and Biological Sciences Research Council

  1/10/14 → 30/09/19

  Project: Research

  • Sequence Alignment 100%
  • Web Services 48%
  • Genetic Variation 47%
  • RNA Secondary Structure 44%
  • angiotensin converting enzyme 2 43%

• Extending The Jalview Resource for Biological Sequence Alignment and Analysis (Biomedical Resource application)

  Barton, G.

  Wellcome Trust

  1/09/14 → 28/02/21

  Project: Research

  • SARS Virus 100%
  • Sequence Alignment 61%
  • Barton Reaction 52%
  • angiotensin converting enzyme 2 50%
  • Ankyrin Repeat 48%

• Hidden Fats: Allosteric and Direct Mechanisms of Lipid Signalling Through GPCRs (CASE Studentship)

  Zachariae, U.

  Biotechnology and Biological Sciences Research Council

  1/04/14 → 31/03/19

  Project: Research

• Developing Genomic Analysis of Clostridium Difficile

  Barton, G. & Marwick, C.

  1/04/13 → 1/07/13

  Project: Research

• The Dundee Resource for Protein Structure Prediction and Sequence Analysis

  Barton, G.

  Biotechnology and Biological Sciences Research Council

  1/03/13 → 31/08/18

  Project: Research

  • SARS Virus 100%
  • angiotensin converting enzyme 2 67%
  • Sequence Alignment 63%
  • Proteins 46%
  • Secondary Protein Structure 38%

• Dermatology and Genetic Medicine (Strategic Grant) (Joint with Kings College London)

  Barton, G., Campbell, P., Leigh, I., McLean, I. & Wyatt, P.

  Wellcome Trust

  1/08/12 → 30/04/19

  Project: Research

  • Atopic Dermatitis 100%
  • filaggrin 69%
  • Mutation 69%
  • Skin 57%
  • Loss of Function Mutation 49%

• Determination of Authentic Substrates for Parkinson's Disease Associated Protein Kinases, LRRK and PINK1 (supplement to Clinical Fellowship)

  Barton, G., Muqit, M. & Simpson, G.

  1/07/12 → 31/12/15

  Project: Research

  • Arabidopsis Thaliana 100%
  • Arabidopsis 73%
  • Gene Expression 70%
  • Differential Expression 69%
  • RNA 67%

• The Non-Coding Arabidopsis Genome

  Barton, G. & Simpson, G.

  1/07/12 → 31/12/15

  Project: Research

  • Arabidopsis 100%
  • Arabidopsis Thaliana 68%
  • RNA Sequence Analysis 53%
  • Gene Expression 48%
  • Differential Expression 47%

• Human and Mouse Genetics Studies of Filaggrin-Related Proteins in Eczema and Allergy (Joint with Trinity College Dublin)

  Barton, G. & McLean, I.

  Wellcome Trust

  1/10/10 → 28/02/14

  Project: Research

  • Atopic Dermatitis 100%
  • filaggrin 92%
  • Loss of Function Mutation 41%
  • Occupational Dermatitis 26%
  • Desmoglein 1 25%

• Aref#d: 21678. Elucidating Mechanisms and Roles of Alternative Polyadenylation

  Barton, G. & Simpson, G.

  1/12/09 → 16/05/13

  Project: Research

  • Arabidopsis Thaliana 100%
  • Arabidopsis 73%
  • Gene Expression 70%
  • Differential Expression 69%
  • RNA 67%

• Aref#d: 21202. Jalview: A Sequence Analysis Resource

  Barton, G. & Martin, D.

  1/10/09 → 30/09/14

  Project: Research

  • angiotensin converting enzyme 2 100%
  • SARS Virus 99%
  • Databases 46%
  • Glycoproteins 32%
  • Proteins 24%