Computational Biology

Projects

Projects per year 2009 2009 2012 2013 2014 2015 2018 2021 2024 2028

• 4 Active
• 8 Not started
• 18 Finished

Projects per year

Search results

• Active

  AMS Springboard

  Igaev, M. (Investigator)

  Academy of Medical Sciences

  1/11/24 → 31/10/26

  Project: Research

• The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP) - 2023 and Beyond

  Abbott, J. (Investigator), Barton, G. (Investigator) & MacGowan, S. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/09/24 → 31/08/28

  Project: Research

• The Jalview Resource for Biological Sequence, Structure and Function Analysis: 2019 and Beyond

  Barton, G. (Investigator) & Procter, J. (Investigator)

  1/01/21 → 31/12/26

  Project: Research

  • Ligand Binding 100%
  • Binding Site 100%
  • Missense 66%
  • Protein Binding Site 66%
  • Protein Ligand 66%

• Machine Learning Methods to Re-Annotate Histone Modifications with Locus-specific Functional Classification (Future Leaders Fellowship)

  Owen-Hughes, T. (Investigator) & Schweikert, G. (Investigator)

  Medical Research Council

  1/11/20 → 31/10/25

  Project: Research

  • Biological Research 100%
  • Epigenetic Modification 100%
  • Epigenetics 100%
  • Machine Learning 100%
  • Individual-specific 100%
• Not started

  Streptococcus pneumoniae metabolic preferences as drivers of infection outcomes

  Drost, H. (Investigator) & Neill, D. (Investigator)

  Project: Research

• Extension to College of Life Sciences Research Complex to Create a Centre for Translational and Interdisciplinary Research (Wolfson Award)

  Barton, G. (Investigator), Chaplain, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Gilbert, I. (Investigator), Hopkins, A. (Investigator), Lamond, A. (Investigator), Swedlow, J. (Investigator) & Wyatt, P. (Investigator)

  Project: Research

• Developing Orphan Crops Genome Annotation (GCRF Round 2020/21)

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  Project: Research

• Transforming the Annotation of Neglected Crop Genomes (GCRF)

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  Project: Research

• Harnessing Protein Search at Tree-of-Life Scale to Explore the Molecular Principles of Heterochrony

  Drost, H. (Investigator)

  Project: Research

• A Sensitive DNA and Protein Alignment Resource to Enable Bioinformatics/AI research in the Million Genomes Era (24BBR)

  Abbott, J. (Investigator), Barton, G. (Investigator) & Drost, H. (Investigator)

  Project: Research

• Sparking Impact Award

  Barton, G. (Investigator)

  Project: Research

• Adaptive Sequencing of Evolutionarily Distant Disease Resistance Genes Using Nanopore (Joint with University of Cambridge)

  Barton, G. (Investigator), Parker, M. (Investigator) & Simpson, G. (Investigator)

  Project: Research

• Finished

  Unlocking The Alternative Splicing Code

  Lamond, A. (Investigator) & Schweikert, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/03/24 → 28/02/25

  Project: Research

• GPU-Based Machine Learning System For Fundamental Biological Research

  Barton, G. (Investigator), Gilbert, I. (Investigator), Lamond, A. (Investigator), Owen-Hughes, T. (Investigator), Pisliakov, A. (Investigator), Schweikert, G. (Investigator), Sknepnek, R. (Investigator), Swedlow, J. (Investigator), Weijer, K. (Investigator) & Zachariae, U. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/08/21 → 31/07/22

  Project: Research

  • Biological Research 100%
  • Dundee 100%
  • Life Sciences 50%

• Control of PolyA Site Choice by m6A RNA Modification

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/07/21 → 13/02/25

  Project: Research

  • 5′ Splice Site 100%
  • U6 snRNA 70%
  • Pre-mRNA 50%
  • Precursor mRNA 50%
  • Eukaryote 50%

• Novel Machine Learning Techniques to Elucidate Function and Dynamics of Epigenomic Mechanisms

  Schweikert, G. (Investigator)

  Academy of Medical Sciences

  15/02/21 → 31/12/22

  Project: Research

  • DNA Methyltransferase 1 (DNMT1) 100%
  • Epigenetic Reprogramming 100%
  • Anaplastic Lymphoma Kinase 100%
  • Nucleophosmin 1 (NPM1) 100%
  • Lymphomagenesis 100%

• Unravelling the Barley Genetic Control of the Rhizosphere Microbiota

  Barton, G. (Investigator), Bulgarelli, D. (Investigator) & Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  17/12/18 → 16/05/22

  Project: Research

  • Microflora 100%
  • Barley 68%
  • Microbiota 61%
  • Rhizosphere Microbiome 58%
  • Plant Microbiome 56%

• The Dundee Resource for Sequence Analysis and Structure Prediction. RELATED TO 36262A, B, C AND D

  Barton, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/09/18 → 31/08/24

  Project: Research

  • Missense 100%
  • Missense Variants 86%
  • Spike 86%
  • SARS Coronavirus 86%
  • Angiotensin-converting Enzyme 2 (ACE2) 74%

• Diversifying Transcription Termination Function

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/06/15 → 31/05/19

  Project: Research

  • RNA Sequencing 100%
  • Arabidopsis 100%
  • RNA Sequencing (RNA-seq) 86%
  • RNA Sequence 80%
  • Arabidopsis Thaliana 65%

• The Arabidopsis Epitranscriptome (Joint with University of Nottingham)

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/15 → 31/03/19

  Project: Research

  • RNA Sequencing 100%
  • Arabidopsis 87%
  • RNA Sequencing (RNA-seq) 86%
  • RNA Sequence 80%
  • Arabidopsis Thaliana 61%

• The Jalview Resource for Sequence Analysis and Annotation (Bioinformatics and Biomedical Resource Fund)

  Barton, G. (Investigator) & Procter, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/10/14 → 30/09/19

  Project: Research

  • Missense Variants 100%
  • Missense 91%
  • Spike 88%
  • SARS Coronavirus 88%
  • Angiotensin-converting Enzyme 2 (ACE2) 76%

• Extending The Jalview Resource for Biological Sequence Alignment and Analysis (Biomedical Resource application)

  Barton, G. (Investigator)

  1/09/14 → 28/02/21

  Project: Research

  • Missense 100%
  • Missense Variants 83%
  • SARS Coronavirus 83%
  • Spike 83%
  • Angiotensin-converting Enzyme 2 (ACE2) 69%

• Developing Genomic Analysis of Clostridium Difficile

  Barton, G. (Investigator) & Marwick, C. (Investigator)

  1/04/13 → 1/07/13

  Project: Research

• The Dundee Resource for Protein Structure Prediction and Sequence Analysis

  Barton, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/03/13 → 31/08/18

  Project: Research

  • Missense 100%
  • Missense Variants 83%
  • Spike 73%
  • SARS Coronavirus 73%
  • Angiotensin-converting Enzyme 2 (ACE2) 63%

• Dermatology and Genetic Medicine (Strategic Grant) (Joint with Kings College London)

  Barton, G. (Investigator), Campbell, P. (Investigator), Hickerson, R. (Investigator), Leigh, I. (Investigator), McLean, I. (Investigator) & Wyatt, P. (Investigator)

  1/08/12 → 30/04/19

  Project: Research

  • Atopic Dermatitis 100%
  • Palmoplantar Keratoderma 38%
  • Gain-of-function mutation 33%
  • Filaggrin 32%
  • Epidermis 29%

• Determination of Authentic Substrates for Parkinson's Disease Associated Protein Kinases, LRRK and PINK1 (supplement to Clinical Fellowship)

  Barton, G. (Investigator), Muqit, M. (Investigator) & Simpson, G. (Investigator)

  1/07/12 → 31/12/15

  Project: Research

  • RNA Sequencing 100%
  • RNA Sequencing (RNA-seq) 89%
  • RNA Sequence 84%
  • RNA 63%
  • Arabidopsis Thaliana 56%

• The Non-Coding Arabidopsis Genome

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  1/07/12 → 31/12/15

  Project: Research

  • RNA Sequencing 100%
  • RNA Sequencing (RNA-seq) 89%
  • RNA Sequence 84%
  • RNA 63%
  • Arabidopsis Thaliana 56%

• Human and Mouse Genetics Studies of Filaggrin-Related Proteins in Eczema and Allergy (Joint with Trinity College Dublin)

  Barton, G. (Investigator) & McLean, I. (Investigator)

  1/10/10 → 28/02/14

  Project: Research

  • Atopic Dermatitis 100%
  • Filaggrin 43%
  • Loss of Function Mutation 36%
  • Gain-of-function mutation 34%
  • Mutation in the Filaggrin Gene 27%

• Aref#d: 21678. Elucidating Mechanisms and Roles of Alternative Polyadenylation

  Barton, G. (Investigator) & Simpson, G. (Investigator)

  1/12/09 → 16/05/13

  Project: Research

  • RNA Sequencing 100%
  • RNA Sequencing (RNA-seq) 89%
  • RNA 86%
  • Alternative Polyadenylation 80%
  • Arabidopsis Thaliana 78%

• Aref#d: 21202. Jalview: A Sequence Analysis Resource

  Barton, G. (Investigator) & Martin, D. (Investigator)

  1/10/09 → 30/09/14

  Project: Research

  • Missense Variants 100%
  • Missense 91%
  • Spike 88%
  • SARS Coronavirus 88%
  • Angiotensin-converting Enzyme 2 (ACE2) 76%