DArcy Thompson Unit

Projects

Projects per year 2009 2009 2011 2012 2013 2014 2021

• 11 Not started
• 48 Finished

Projects per year

Search results

• Finished

  Rapid Research in Covid -19 Programme

  Barrable, A. (Investigator), Belch, J. (Investigator), Boehnke, J. (Investigator), Booth, D. (Investigator), Brown, A. (Investigator), Cantrell, D. (Investigator), Chalmers, J. (Investigator), Coleman, S. (Investigator), Connell, D. (Investigator), Cuschieri, A. (Investigator), Dicker, A. (Investigator), Doney, A. (Investigator), Eftimie, R. (Investigator), Fang, M. (Investigator), Farre, A. (Investigator), Gamble, C. (Investigator), Howden, A. (Investigator), Krstajic, N. (Investigator), Lamond, A. (Investigator), Moraga Gonzalez, I. (Investigator), Palmer, C. (Investigator), Parcell, B. (Investigator), Pearson, E. (Investigator), Shoemark, A. (Investigator) & Sixsmith, J. (Investigator)

  1/06/20 → 30/09/21

  Project: Research

  • COVID-19 100%
  • Neutrophils 66%
  • Hyperinflammation 33%
  • Resilience 33%
  • T Cell Activation 33%

• A Reference Transcript Database for Improved Analysis of RNA-seq Data from Barley

  Brown, J. (Investigator) & Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/10/18 → 30/09/20

  Project: Research

  • Barley 100%
  • RNA Sequencing 90%
  • Transcriptome 61%
  • RNA Sequencing (RNA-seq) 57%
  • Reference Transcriptome 55%

• Probing the Mechanism of the Tat Secretion System from the Soil Bacterium Bacillus Subtilis

  Palmer, T. (Investigator)

  5/06/17 → 4/08/17

  Project: Research

• Dynamic Re-programming of the Cold Transcriptome in Arabidopsis (Joint with JHI)

  Brown, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/17 → 31/07/20

  Project: Research

  • Alternative Splicing 100%
  • Arabidopsis 88%
  • Gene Expression 43%
  • RNA Sequencing 41%
  • RNA Sequencing (RNA-seq) 38%

• Development of SUPPA for Alternative Splicing Analysis from RNA-Seq Data in Plants Across Multiple Conditions

  Brown, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/10/16 → 14/11/17

  Project: Research

  • Alternative Splicing 100%
  • Arabidopsis 53%
  • Alternative RNA Splicing 50%
  • Isoform 33%
  • Splice Isoforms 31%

• Identification of Substrates and Roles in Virulence of the Staphylococcus Aureus Ess Protein Secretion System (Investigator Award)

  Palmer, T. (Investigator)

  1/10/16 → 30/09/21

  Project: Research

  • Twin-arginine Translocation 100%
  • Twin-arginine 100%
  • Staphylococcus Aureus 100%
  • Type VII Secretion System 100%
  • Interspecies Competition 100%

• Characterisation of the Assembled State of the Tat Protein Transport System

  Palmer, T. (Investigator)

  Biotechnology and Biological Sciences Research Council

  12/09/16 → 11/09/19

  Project: Research

  • Arginine 100%
  • Twin-arginine Translocation 90%
  • Mitochondrial Membrane Transport Protein 90%
  • Translocase 90%
  • Carrier Protein 90%

• Construction and Refinement of Reference Transcript Dataset Annotations for Fast and Accurate Transcript Quantification in Barley and Potato (EASTBIO)

  Brown, J. (Investigator) & Zhang, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  5/09/16 → 4/09/20

  Project: Research

• Characterisation of the Ess Protein Secretion System of Staphylococcus Aureus a Key Virulence Factor

  Hunter, B. (Investigator) & Palmer, T. (Investigator)

  Medical Research Council

  1/04/15 → 31/05/18

  Project: Research

  • Type VII Secretion System 100%
  • Staphylococcus Aureus 98%
  • T7SS 92%
  • Secretion (Process) 68%
  • Secretion Systems 32%

• High Throughput Biolayer Interferometry at Dundee for Anti-Microbial and Interaction Studies

  Birch, P. (Investigator), Ciulli, A. (Investigator), Fairlamb, A. (Investigator), Gray, D. (Investigator), Hunter, B. (Investigator), Owen-Hughes, T. (Investigator), Palmer, T. (Investigator), Ryan, R. (Investigator), Sargent, F. (Investigator), Stanley-Wall, N. (Investigator) & van Aalten, D. (Investigator)

  Biotechnology and Biological Sciences Research Council

  22/01/15 → 21/01/16

  Project: Research

• Exploiting Synergies in Barley Research (Partnering Award)

  Brown, J. (Investigator), Halpin, C. (Investigator) & Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  26/06/14 → 25/12/18

  Project: Research

  • Barley 100%
  • Grains 72%
  • Synthase 55%
  • Glucan 47%
  • Genome-Wide Association Study 45%

• A Tissue Bank Resource for the Near-Patient Study of Cell Pathology in Rare genetic Diseases

  Forgie, I. (Investigator), Land, S. (Investigator) & Mehta, A. (Investigator)

  Anonymous Trust

  1/06/14 → 31/05/15

  Project: Research

• Characterisation of a Novel Staphylococcus Aureus Virulence System Critical to Lung Colonisation in Cystic Fibrosis

  Chalmers, J. (Investigator) & Palmer, T. (Investigator)

  1/06/14 → 31/05/16

  Project: Research

• Co-Ordinating Different Protein Translocation Machineries During Assembly of a Membrane Protein

  Palmer, T. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/14 → 31/07/17

  Project: Research

  • Tat Pathway 100%
  • Membrane Protein 100%
  • Transmembrane Protein 88%
  • Twin-arginine Translocation 66%
  • Twin-arginine 66%

• Exploiting the Structure of the Twin-Arginine Protein Translocase Core (Joint with Oxford University)

  Palmer, T. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/03/14 → 28/02/17

  Project: Research

  • TatC 100%
  • Mitochondrial Membrane Transport Protein 97%
  • Translocase 97%
  • Carrier Protein 97%
  • Arginine 86%

• Ninewells Cancer Campaign - Studentship

  Stavridis, M. (Investigator)

  1/10/13 → 30/09/16

  Project: Research

• Proteomic Analysis of the Electrical Synaptosome

  Hormuzdi, S. (Investigator) & Trost, M. (Investigator)

  Anonymous Trust

  1/10/13 → 31/07/17

  Project: Research

• Structure Function and Host Control of the Barley Rhizosphere Microbiota (RSE/Scottish Government Personal Research Fellowship co-funded by Marie Curie Actions 2013)

  Brown, J. (Investigator) & Bulgarelli, D. (Investigator)

  Royal Society of Edinburgh

  1/10/13 → 30/09/18

  Project: Research

• Cellular Reprogramming as a Tool to Characterise the Cellular Electrophysiology of Familial Arrhythmia

  Ashford, M. (Investigator), Berg, J. (Investigator), Choy, A.-M. (Investigator) & Stavridis, M. (Investigator)

  1/06/13 → 31/07/15

  Project: Research

• Cellular Reprogramming as a Tool to Characterise the Cellular Electrophysiology of Familial Arrhythmia Syndromes

  Ashford, M. (Investigator), Berg, J. (Investigator), Choy, A.-M. (Investigator), Stavrakis, S. (Investigator) & Stavridis, M. (Investigator)

  Anonymous Trust

  1/05/13 → 30/04/14

  Project: Research

• SiLAC Proteomics for Quantitation of Protein Isoforms from Alternative Splicing in Arabidopsis Seedlings

  Brown, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/13 → 31/03/14

  Project: Research

  • Arabidopsis 100%
  • Stable Isotope Labeling 50%
  • Transcript Level 50%
  • Transcriptome 50%
  • Quantitative Proteomics 50%

• Mechanisms and Function of Alternative Splicing in the Plant Circadian Clock (Joint with University of Glasgow)

  Brown, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/13 → 30/09/16

  Project: Research

  • Alternative Splicing 100%
  • Arabidopsis 58%
  • Isoform 39%
  • RNA Sequencing 35%
  • Transcriptome 28%

• Molecular Characterisation of Bacterial Interspecies Signalling in Polymicrobial Chronic Lung Infection: A Potential Target for Therapeutic Intervention (Senior Research Fellowship)

  Palmer, T. (Investigator) & Ryan, R. (Investigator)

  1/03/13 → 28/02/18

  Project: Research

  • Virulence 100%
  • Signal Transduction 80%
  • Biofilm 78%
  • Cyclic GMP 75%
  • Xanthomonas campestris 62%

• Substrate-Receptor Interactions in the Tat Protein Transport Pathway (Joint with University of Oxford)

  Palmer, T. (Investigator)

  Medical Research Council

  1/03/13 → 29/02/16

  Project: Research

• The Role in ESX-1, a Novel Protein Secretion System, in Staphylococcus Aureus Virulence (Clinical Fellowship - James Chalmers)

  Chalmers, J. (Investigator) & Palmer, T. (Investigator)

  1/01/13 → 31/12/15

  Project: Research

  • Staphylococcus Aureus 100%
  • Mortality Risk 100%
  • Exacerbation Rate 100%
  • Microbial Diversity 100%
  • Type VII Secretion System 100%

• A Tissue Bank Resource to Investigate the Link Between VEGF-A Signalling and Pulmonary Cyst Formation in BHD Syndrome

  Land, S. (Investigator) & Mehta, A. (Investigator)

  1/12/12 → 31/07/16

  Project: Research

• Regulation of (1,3;1,4) Beta-Glucan Synthesis in the Grasses (Joint with James Hutton Institute)

  Brown, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  5/11/12 → 4/11/15

  Project: Research

• Molecular Characterisation of HvAP2-Like and HvSPL Transcription Factors in Barley (Fellowship: Dr Sarah McKim)

  Brown, J. (Investigator) & McKim, S. (Investigator)

  Royal Society of Edinburgh

  1/10/12 → 31/10/18

  Project: Research

• Construction and Characterisation of Anti-Tumour Magnetic Fusion Proteins for Use in Diagnostics and Therapeutics

  Woof, J. (Investigator)

  1/09/12 → 30/09/16

  Project: Research

• Investigating Physiological Substrates for HDAC7: Implications for HDAC7-Mediated Regulation of Lymphocyte Development

  MacKenzie, M. (Investigator) & Matthews, S. (Investigator)

  Anonymous Trust

  1/07/12 → 30/06/13

  Project: Research

• Probing the Mechanism of Protein Export by the Bacterial Tat Transport System (Joint with University of Oxford)

  Palmer, T. (Investigator)

  Medical Research Council

  1/01/12 → 31/03/15

  Project: Research

  • Arginine 100%
  • TatC 87%
  • TatB 65%
  • Twin-arginine Translocation 58%
  • Mitochondrial Membrane Transport Protein 58%

• Effects of GlcNAc Signalling Disruption on ES Cell Differentiation

  Stavridis, M. (Investigator)

  1/12/11 → 30/11/12

  Project: Research

• Effects of LAT1 Amino Acid Transporter (SLC7AS) Gene Deletion on Mammalian Growth Nutrient Signalling and Foetal Development

  Taylor, P. (Investigator)

  3/10/11 → 2/10/14

  Project: Research

• Non-Genomic Mechanisms Stabilizing the Abundance of SNAT2, a Nutrient Transceptor Protein, in Response to Diverse Catabotic Signals

  Hundal, H. (Investigator) & Taylor, P. (Investigator)

  3/10/11 → 2/07/15

  Project: Research

  • Amino Acids 100%
  • Amino Acid Transporter 80%
  • Mammalian Target of Rapamycin (mTOR) 59%
  • SLC38A2 56%
  • SNAT2 56%

• The Relationship Between Micronutrient Status and Amino Acid Metabolism (RERAD) (Year 1)

  Hundal, H. (Investigator) & Taylor, P. (Investigator)

  Scottish Government

  3/10/11 → 31/03/16

  Project: Research

• The Molecular Mechanisms Underlying Secretory Component-Mediated Activation of Eosinophils (Foundation Grant)

  Woof, J. (Investigator)

  Asthma UK

  1/10/11 → 30/09/12

  Project: Research

• Probing the Mechanism of Protein Export by the Bacterial Tat Transport System (Wolfson Research Merit Award)

  Palmer, T. (Investigator)

  1/08/11 → 31/07/16

  Project: Research

• Characterisation of the Bacterial Proteins YjeE, YeaZ and YgjD and Evaluation as a Potential Novel Antimicrobial Target (Clinical Pre-Doctoral Fellowship - James Cargill)

  Cargill, J. (Investigator) & Palmer, T. (Investigator)

  Medical Research Council

  1/08/11 → 31/07/14

  Project: Research

• Signalling by Post-translational Modifications in Embryonic Stem Cells

  Stavridis, M. (Investigator)

  Anonymous Trust

  1/05/11 → 30/04/13

  Project: Research

• Biogenesis of a Respiratory Complex Essential for Viability of Pathogenic Mycobacteria

  Palmer, T. (Investigator)

  Medical Research Council

  1/09/10 → 31/08/13

  Project: Research

  • Arginine 100%
  • Protein Transport 90%
  • Membrane Protein 75%
  • Twin-arginine 66%
  • Twin-arginine Translocation 60%

• Aref#d: 21992. Form and Function in the ESX-1 Secretion System; Elucidation of Mechanism and Structural Determinants of Bacterial Virulence

  Hunter, B. (Investigator) & Palmer, T. (Investigator)

  1/04/10 → 18/08/13

  Project: Research

  • Staphylococcus Aureus 100%
  • Type VII Secretion System 100%
  • T7SS 85%
  • Nuclease 50%
  • Interspecies Competition 50%

• Aref#d: 21456. mTOR as a Regulator of Airway and Vascular Development in the Fetal Lung

  Jovanovic, A. (Investigator) & Land, S. (Investigator)

  9/11/09 → 8/05/13

  Project: Research

• Aref#d: 21202. Jalview: A Sequence Analysis Resource

  Barton, G. (Investigator) & Martin, D. (Investigator)

  1/10/09 → 30/09/14

  Project: Research

  • Missense Variants 100%
  • Missense 91%
  • Spike 88%
  • SARS Coronavirus 88%
  • Angiotensin-converting Enzyme 2 (ACE2) 76%

• Aref#d: 21936. Mechanisms of Virulence Acquisition During Phytophthora-Host Associations (RSE/Scottish Government Marie Curie Personal Research Fellowship) - Dr Edgar Huitema

  Brown, J. (Investigator) & Huitema, E. (Investigator)

  Royal Society of Edinburgh

  1/10/09 → 30/09/14

  Project: Research

• Aref#d: 21852. Understanding the Role of Class IIa-Histone Deacetylases in Normal B-Cell Development and Function (Career Establishment Award)

  Matthews, S. (Investigator)

  1/07/09 → 31/03/15

  Project: Research

• Aref#d: 21864. In Vivo Study of Domain Determinants for Electrical Synapse Assembly

  Hormuzdi, S. (Investigator)

  Anonymous Trust

  1/07/09 → 31/07/13

  Project: Research

• Aref#d: 20175. Molecular Mechanisms Control and Cellular Consequences of rRNA Gene Transcriptions by RNA Polymerase (Programme Grant)

  Zomerdijk, J. (Investigator)

  6/04/09 → 5/12/14

  Project: Research

  • RNA Polymerase I 100%
  • Transcription 66%
  • RNA Gene 46%
  • Polis 42%
  • Polymerase 40%

• Aref#d: 20710. Characterisation of the Ubiquitous Sulfate Transporter from the SulP Family (RSE/Scottish Government Personal Research Fellowship : Dr A Javelle)

  Javelle, A. (Investigator) & Palmer, T. (Investigator)

  Royal Society of Edinburgh

  1/02/09 → 31/01/14

  Project: Research