DArcy Thompson Unit

Research Output 1987 2020

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2 Citations (Scopus)

5-Hydroxytryptamine3 receptor mediated responses on adult rabbit nodose ganglion neurones in cell culture

Peters, J. A., Malone, H. M. & Lambert, J. J., 1 Jan 1990, In : European Journal of Pharmacology. 183, 3, p. 1112 1 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

A barley cultivation-associated polymorphism conveys resistance to powdery mildew

Piffanelli, P., Ramsay, L., Waugh, R., Benabdelmouna, A., D'Hont, A., Hollricher, K., Jørgensen, J. H., Schulze-Lefert, P. & Panstruga, R., 19 Aug 2004, In : Nature. 430, 7002, p. 887-891 5 p.

Research output: Contribution to journalArticle

Hordeum
Alleles
Tandem Repeat Sequences
Disease Resistance
Agriculture
1 Citation (Scopus)
54 Downloads (Pure)

Absence of curli in soil-persistent Escherichia coli is mediated by a C-di-GMP signaling defect and suggests evidence of biofilm-independent niche specialization

Somorin, Y. M., Vollmerhausen, T., Waters, N., Pritchard, L., Abram, F., Brennan, F. & O'Byrne, C., 22 Jun 2018, In : Frontiers in Microbiology. 9, p. 1-13 13 p., 1340.

Research output: Contribution to journalArticle

Open Access
File
Biofilms
Soil
Escherichia coli
Quartz
Enterobacteriaceae
48 Citations (Scopus)

Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

Preston, R. S., Philp, A., Claessens, T., Gijezen, L., Dydensborg, A. B., Dunlop, E. A., Harper, K. T., Brinkhuizen, T., Menko, F. H., Davies, D. M., Land, S. C., Pause, A., Baar, K., van Steensel, M. & Tee, A. R., 2011, In : Oncogene. 30, 10, p. 1159-1173 15 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

A comparative analysis of transcript abundance using SAGE and Affymetrix arrays

Ibrahim, A. F. M., Hedley, P. E., Cardle, L., Kruger, W., Marshall, D. F., Muehlbauer, G. J. & Waugh, R., 1 Jul 2005, In : Functional and Integrative Genomics. 5, 3, p. 163-174 12 p.

Research output: Contribution to journalArticle

Gene Expression
Gene Expression Profiling
Hordeum
Libraries
Embryonic Structures
1 Citation (Scopus)
30 Downloads (Pure)

A comparison of mainstream genotyping platforms for the evaluation and use of barley genetic resources

Darrier, B., Russell, J., Milner, S. G., Hedley, P. E., Shaw, P. D., Macaulay, M., Ramsay, L., Halpin, C., Mascher, M., Fleury, D. L., Langridge, P., Stein, N. & Waugh, R., 26 Apr 2019, In : Frontiers in Plant Science. 10, p. 1-14 14 p., 544.

Research output: Contribution to journalArticle

Open Access
File
genetic resources
genotyping
single nucleotide polymorphism
barley
gene frequency
40 Citations (Scopus)
Hemeproteins
Turtles
Hepatocytes
Oxygen
Proteins
224 Citations (Scopus)

A high density barley microsatellite consensus map with 775 SSR loci

Varshney, R. K., Marcel, T. C., Ramsay, L., Russell, J., Röder, M. S., Stein, N., Waugh, R., Langridge, P., Niks, R. E. & Graner, A., 1 Apr 2007, In : Theoretical and Applied Genetics. 114, 6, p. 1091-1103 13 p.

Research output: Contribution to journalArticle

Hordeum
Microsatellite Repeats
barley
microsatellite repeats
loci
25 Downloads (Pure)

A highly mutagenised barley (cv. Golden Promise) TILLING population coupled with strategies for screening-by-sequencing

Schreiber, M., Barakate, A., Uzrek, N., Macaulay, M., Sourdille, A., Morris, J., Hedley, P. E., Ramsay, L. & Waugh, R., 24 Aug 2019, In : Plant Methods. 15, p. 1-14 14 p., 99.

Research output: Contribution to journalArticle

Open Access
File
Hordeum
barley
screening
mutation
Mutation
1 Citation (Scopus)

Alternate thermoregulation and functional binding of Escherichia coli type 1 fimbriae in environmental and animal isolates

Marshall, J., Rossez, Y., Mainda, G., Gally, D. L., Daniell, T. J. & Holden, N. J., Nov 2016, In : FEMS Microbiology Letters. 363, 22, p. 1-8 8 p.

Research output: Contribution to journalArticle

Mannans
Body Temperature Regulation
Escherichia coli
Plant Roots
Temperature
37 Citations (Scopus)

Alternative splicing of the human IgA Fc receptor CD89 in neutrophils and eosinophils

Pleass, R. J., Andrews, P. D., Kerr, M. A. & Woof, J. M., 15 Sep 1996, In : Biochemical Journal. 318, 3, p. 771-777 7 p.

Research output: Contribution to journalArticle

Fc Receptors
Alternative Splicing
Eosinophils
Immunoglobulin A
Neutrophils
6 Citations (Scopus)
84 Downloads (Pure)

A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions

Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In : Plant Methods. 13, p. 1-12 12 p., 74.

Research output: Contribution to journalArticle

Open Access
File
hyperspectral imagery
raspberries
methodology
reflectance
Rubus
51 Citations (Scopus)
Amiloride
Biosynthesis
Amplification
Lipopolysaccharides
Anti-Inflammatory Agents

A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 18 Oct 2019, In : FEBS Letters.

Research output: Contribution to journalArticle

Missense Mutation
Intellectual Disability
Catalytic Domain
X ray crystallography
Stem cells
103 Citations (Scopus)

Analysis of quantitative traits in barley by the use of amplified fragment length polymorphisms

Powell, W., Thomas, W. T. B., Baird, E., Lawrence, P., Booth, A., Harrower, B., McNicol, J. W. & Waugh, R., 1 Jul 1997, In : Heredity. 79, 1, p. 48-59 12 p.

Research output: Contribution to journalArticle

Hordeum
Genome
Enzymes
Restriction Fragment Length Polymorphisms
Chromosomes, Human, Pair 5

Ancient barley landraces adapted to marginal soils demonstrate exceptional tolerance to manganese limitation

Schmidt, S. B., George, T. S., Brown, L. K., Booth, A., Wishart, J., Hedley, P. E., Martin, P., Russell, J. & Husted, S., 15 Dec 2018, In : Annals of Botany.

Research output: Contribution to journalArticle

landraces
manganese
barley
soil
grain yield
38 Citations (Scopus)
Chromaffin Cells
GABA-A Receptors
gamma-Aminobutyric Acid
Action Potentials
Acetylcholine
48 Citations (Scopus)
Nodose Ganglion
Inhibitory Concentration 50
Rabbits
Neurons
Baths
75 Citations (Scopus)
HEK293 Cells
Inhibitory Concentration 50
Zinc
Pharmacology
Methysergide
56 Citations (Scopus)
51 Downloads (Pure)

An eQTL analysis of partial resistance to Puccinia hordei in barley

Chen, X., Hackett, C. A., Niks, R. E., Hedley, P. E., Booth, C., Druka, A., Marcel, T. C., Vels, A., Bayer, M., Milne, I., Morris, J., Ramsay, L., Marshall, D., Cardle, L. & Waugh, R., 6 Jan 2010, In : PLoS ONE. 5, 1, e8598.

Research output: Contribution to journalArticle

Open Access
File
Puccinia hordei
Quantitative Trait Loci
Hordeum
quantitative trait loci
Genes
55 Citations (Scopus)

Anesthetic activity of novel water-soluble 2β-morpholinyl steroids and their modulatory effects at GABA(A) receptors

Anderson, A., Boyd, A. C., Byford, A., Campbell, A. C., Gemmell, D. K., Hamilton, N. M., Hill, D. R., Hill-Venning, C., Lambert, J. J., Maidment, M. S., May, V., Marshall, R. J., Peters, J. A., Rees, D. C., Stevenson, D. & Sundaram, H., 23 May 1997, In : Journal of Medicinal Chemistry. 40, 11, p. 1668-1681 14 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Anesthetics
Steroids
Water
Pregnanolone
15 Citations (Scopus)
48 Downloads (Pure)

An investigation of causes of false positive single nucleotide polymorphisms using simulated reads from a small eukaryote genome

Ribeiro, A., Golicz, A., Hackett, C. A., Milne, I., Stephen, G., Marshall, D., Flavell, A. J. & Bayer, M., 11 Nov 2015, In : BMC Bioinformatics. 16, 1, p. 1-16 16 p., 382.

Research output: Contribution to journalArticle

Open Access
File
Single nucleotide Polymorphism
Nucleotides
Eukaryota
Polymorphism
False Positive
204 Citations (Scopus)

A non-hypoxic, ROS-sensitive pathway mediates TNF-α-dependent regulation of HIF-1α

Haddad, J. J. & Land, S. C., 14 Sep 2001, In : FEBS Letters. 505, 2, p. 269-274 6 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Reactive Oxygen Species
Tumor Necrosis Factor-alpha
Chemical activation
Mitochondria
23 Citations (Scopus)

A novel non-protein-coding infection-specific gene family is clustered throughout the genome of Phytophthora infestans

Avrova, A. O., Whisson, S. C., Pritchard, L., Venter, E., De Luca, S., Hein, I. & Birch, P. R. J., 1 Mar 2007, In : Microbiology. 153, Pt 3, p. 747-759 13 p.

Research output: Contribution to journalArticle

Phytophthora infestans
Genome
Infection
Complementary DNA
Genes
72 Citations (Scopus)

Anoxia-tolerant hepatocytes: Model system for study of reversible metabolic suppression

Buck, L. T., Land, S. C. & Hochachka, P. W., 1 Jul 1993, In : American Journal of Physiology: Regulatory Integrative and Comparative Physiology. 265, 1 , p. R49-R56 8 p.

Research output: Contribution to journalArticle

Hepatocytes
Adenosine Triphosphate
Trypan Blue
Lactic Acid
Staining and Labeling
5 Citations (Scopus)
43 Downloads (Pure)

Antigen receptor control of methionine metabolism in T cells

Sinclair, L. V., Howden, A., Brenes Murillo, A., Spinelli, L., Hukelmann, J., Macintyre, A. N., Liu, X., Thomson, S., Taylor, P., Rathmell, J. C., Locasale, J. W., Lamond, A. & Cantrell, D. A., 27 Mar 2019, In : eLife. 8, 29 p., e44210.

Research output: Contribution to journalArticle

Open Access
File
Antigen Receptors
T-cells
Metabolism
Methionine
T-Lymphocytes
223 Citations (Scopus)

Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1a and NF-kB Redox Sensitivity: EVIDENCE FOR INHIBITION BY GLUTATHIONE OXIDATION IN ALVEOLAR EPITHELIAL CELLS

Haddad, J. J. E., Olver, R. E. & Land, S. C., 14 Jul 2000, In : Journal of Biological Chemistry. 275, 28, p. 21130-21139 10 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Glutathione Disulfide
NF-kappa B
Oxidation-Reduction
Glutathione
47 Citations (Scopus)

A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture.

Nooney, J. M., Peters, J. A. & Lambert, J. J., 1 Sep 1992, In : The Journal of Physiology. 455, 1, p. 503-527 25 p.

Research output: Contribution to journalArticle

Hexamethonium
Chromaffin Cells
Nicotinic Receptors
Trimethaphan
Mecamylamine
47 Downloads (Pure)

Application of a Sensitive and Reproducible Label-Free Proteomic Approach to Explore the Proteome of Individual Meiotic-Phase Barley Anthers

Lewandowska, D., Zhang, R., Colas, I., Uzrek, N. & Waugh, R., 2 Apr 2019, In : Frontiers in Plant Science. 10, p. 1-15 15 p., 393.

Research output: Contribution to journalArticle

Open Access
File
proteome
proteomics
anthers
meiosis
barley
98 Citations (Scopus)

A representative, highly informative 'genotyping set' of barley SSRs

Macaulay, M., Ramsay, L., Powell, W. & Waugh, R., 26 Jun 2001, In : Theoretical and Applied Genetics. 102, 6-7, p. 801-809 9 p.

Research output: Contribution to journalArticle

Hordeum
genotyping
barley
Genotype
genotype
105 Citations (Scopus)

A retrospective analysis of spring barley germplasm development from 'foundation genotypes' to currently successful cultivars

Russell, J. R., Ellis, R. P., Thomas, W. T. B., Waugh, R., Provan, J., Booth, A., Fuller, J., Lawrence, P., Young, G. & Powell, W., 1 Dec 2000, In : Molecular Breeding. 6, 6, p. 553-568 16 p.

Research output: Contribution to journalArticle

spring barley
Hordeum
germplasm
Genotype
genotype
5 Citations (Scopus)
59 Downloads (Pure)

A reversible light- and genotype-dependent acquired thermotolerance response protects the potato plant from damage due to excessive temperature

Trapero-Mozos, A., Ducreux, L. J. M., Bita, C. E., Morris, W., Wiese, C., Morris, J. A., Paterson, C., Hedley, P. E., Hancock, R. D. & Taylor, M., Jun 2018, In : Planta. 247, 6, p. 1377-1392 16 p.

Research output: Contribution to journalArticle

Open Access
File
Solanum tuberosum
heat tolerance
Genotype
potatoes
Light
493 Citations (Scopus)

A simple sequence repeat-based linkage map of Barley

Ramsay, L., Macaulay, M., Degli Ivanissevich, S., MacLean, K., Cardle, L., Fuller, J., Edwards, K. J., Tuvesson, S., Morgante, M., Massari, A., Maestri, E., Marmiroli, N., Sjakste, T., Ganal, M., Powell, W. & Waugh, R., 1 Dec 2000, In : Genetics. 156, 4, p. 1997-2005 9 p.

Research output: Contribution to journalArticle

Hordeum
Microsatellite Repeats
Population
Cluster Analysis
Flax
37 Citations (Scopus)

A single amino acid confers barbiturate sensitivity upon the GABA ρ1 receptor

Belelli, D., Pau, D., Cabras, G., Peters, J. A. & Lambert, J. J., Jun 1999, In : British Journal of Pharmacology. 127, 3, p. 601-604 4 p.

Research output: Contribution to journalArticle

General Anesthetics
GABA Receptors
GABA-A Receptors
Amino Acids
gamma-Aminobutyric Acid
27 Citations (Scopus)

Association between rDNA alleles and quantitative traits in doubled haploid populations of barley

Powell, W., Thomas, W. T. B., Thompson, D. M., Swanston, J. S. & Waugh, R., 1 Jan 1992, In : Genetics. 130, 1, p. 187-194 8 p.

Research output: Contribution to journalArticle

Haploidy
Hordeum
Ribosomal DNA
Alleles
Population
220 Citations (Scopus)

A structured mutant population for forward and reverse genetics in Barley (Hordeum vulgare L.)

Caldwell, D. G., McCallum, N., Shaw, P., Muehlbauer, G. J., Marshall, D. F. & Waugh, R., 1 Oct 2004, In : Plant Journal. 40, 1, p. 143-150 8 p.

Research output: Contribution to journalArticle

Reverse Genetics
Population Genetics
Hordeum
Hordeum vulgare
barley
33 Downloads (Pure)

AVR2 targets BSL family members, which act as susceptibility factors to suppress host immunity

Turnbull, D., Wang, H., Breen, S., Malec, M., Naqvi, S., Yang, L., Welsh, L., Hemsley, P. A., Zhendong, T., Brunner, F., Gilroy, E. M. & Birch, P. R. J., 1 May 2019, In : Plant Physiology. 180, 1, p. 571-581 11 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Immunity
immunity
Solanum tuberosum
Brassinosteroids
42 Citations (Scopus)

Birt-Hogg-Dubé syndrome is a novel ciliopathy

Luijten, M. N. H., Basten, S. G., Claessens, T., Vernooij, M., Scott, C. L., Janssen, R., Easton, J. A., Kamps, M. A. F., Vreeburg, M., Broers, J. L. V., van Geel, M., Menko, F. H., Harbottle, R. P., Nookala, R. K., Tee, A. R., Land, S. C., Giles, R. H., Coull, B. J. & van Steensel, M., 2013, In : Human Molecular Genetics. 22, 21, p. 4383-4397 15 p.

Research output: Contribution to journalArticle

Estrone
Kidney Neoplasms
Kidney
Ciliopathies
Centrosome
38 Downloads (Pure)

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

Pravata, V., Muha, V., Gundogdu, M., Ferenbach, A., Kakade, P., Vandadi, V., Wilmes, A. C., Borodkin, V., Joss, S., Stavridis, M. & van Aalten, D., 23 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 30, p. 14961-14970 10 p.

Research output: Contribution to journalArticle

Open Access
File
Intellectual Disability
Host Factor 1 Protein
Missense Mutation
Proteome
Catalytic Domain
104 Downloads (Pure)

CDK7 is a component of the integrated stress response regulating SNAT2 (SLC38A2)/System A adaptation in response to cellular amino acid deprivation

Stretton, C., Lipina, C., Hyde, R., Cwiklinski, E., Hoffmann, T. M., Taylor, P. M. & Hundal, H. S., 1 Jun 2019, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1866, 6, p. 978-991 14 p.

Research output: Contribution to journalArticle

Open Access
File
Activating Transcription Factor 4
Amino Acids
Cyclin-Dependent Kinases
alvocidib
Phosphotransferases
19 Citations (Scopus)

Characterisation and functional analysis of two barley caleosins expressed during barley caryopsis development

Liu, H., Hedley, P., Cardle, L., Wright, K. M., Hein, I., Marshall, D. & Waugh, R., 1 Jun 2005, In : Planta. 221, 4, p. 513-522 10 p.

Research output: Contribution to journalArticle

lipid bodies
Hordeum
barley
body protein
fruits

Characterisation of barley resistance to rhynchosporium on chromosome 6HS

Coulter, M., Büttner, B., Hofmann, K., Bayer, M., Ramsay, L., Schweizer, G., Waugh, R., Looseley, M. E. & Avrova, A., Apr 2019, In : Theoretical and Applied Genetics. 132, 4, p. 1089-1107 19 p.

Research output: Contribution to journalArticle

Rhynchosporium
Hordeum
Chromosomes
barley
chromosomes
22 Citations (Scopus)

Characterisation of early transcriptional changes involving multiple signalling pathways in the Mla13 barley interaction with powdery mildew (Blumeria graminis f. sp. hordei)

Hein, I., Campbell, E. I., Woodhead, M., Hedley, P. E., Young, V., Morris, W. L., Ramsay, L., Stockhaus, J., Lyon, G. D., Newton, A. C. & Birch, P. R. J., Mar 2004, In : Planta. 218, 5, p. 803-813 11 p.

Research output: Contribution to journalArticle

Blumeria graminis f. sp. hordei
Hordeum
powdery mildew
Salicylic Acid
barley
43 Citations (Scopus)

Characterization of a human 5‐hydroxytryptamine3 receptor type A (h5‐HT3R‐AS) subunit stably expressed in HEK 293 cells

Hope, A. G., Peters, J. A., Brown, A. M., Lambert, J. J. & Blackburn, T. P., Jul 1996, In : British Journal of Pharmacology. 118, 5, p. 1237-1245 9 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
HEK293 Cells
Granisetron
Serotonin
Pharmacology
4 Citations (Scopus)
18 Downloads (Pure)

Characterization of the ligand binding site of the bovine IgA Fc receptor (bFcαR)

Morton, H. C., Pleass, R. J., Woof, J. M. & Brandtzaeg, P., 24 Dec 2004, In : Journal of Biological Chemistry. 279, 52, p. 54018-54022 5 p.

Research output: Contribution to journalArticle

Open Access
File
Fc Receptors
Immunoglobulin A
Binding Sites
Ligands
Mutation
68 Citations (Scopus)

Chemioxyexcitation (ΔpO2/ROS)-dependent release of IL-1β, IL-6 and TNF-α: Evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium

Haddad, J. J. E., Safieh-Garabedian, B., Saadé, N. E., Kanaan, S. A. & Land, S. C., 7 Feb 2001, In : Cytokine. 13, 3, p. 138-147 10 p.

Research output: Contribution to journalArticle

Interleukin-1
Interleukin-6
Reactive Oxygen Species
Epithelium
Cytokines
30 Citations (Scopus)

Cleavage of a recombinant human immunoglobulin A2 (IgA2)-IgA1 hybrid antibody by certain bacterial IgA1 proteases

Senior, B. W., Dunlop, J. I., Batten, M. R., Kilian, M. & Woof, J. M., Feb 2000, In : Infection and Immunity. 68, 2, p. 463-469 7 p.

Research output: Contribution to journalArticle

Open Access
IgA-specific serine endopeptidase
Bacterial Antibodies
varespladib methyl
Immunoglobulins
Haemophilus influenzae
27 Citations (Scopus)

Cleavage of human IgE mediated by Schistosoma mansoni

Pleass, R. J., Kusel, J. R. & Woof, J. M., Mar 2000, In : International Archives of Allergy and Immunology. 121, 3, p. 194-204 11 p.

Research output: Contribution to journalArticle

Schistosoma mansoni
Immunoglobulin E
Pancreatic Elastase
Immunoglobulin A
Amino Acid Chloromethyl Ketones
20 Citations (Scopus)

Cloning and characterization of an immunoglobulin A Fc receptor from cattle

Morton, H. C., Pleass, R. J., Storset, A. K., Dissen, E., Williams, J. L., Brandtzaeg, P. & Woof, J. M., Feb 2004, In : Immunology. 111, 2, p. 204-211 8 p.

Research output: Contribution to journalArticle

Fc Receptors
Immunoglobulin A
Organism Cloning
Complementary DNA
Immunoglobulin G
138 Citations (Scopus)

Cloning and fnctional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit

Hope, A. G., Downie, D. L., Sutherland, L. A., Lambert, J. J., Peters, J. A. & Burchell, B., 15 Apr 1993, In : European Journal of Pharmacology: Molecular Pharmacology. 245, 2, p. 187-192 6 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Organism Cloning
Clone Cells
Hybridomas
Alternative Splicing