DArcy Thompson Unit

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2016

Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance

Tosoni, K., Cassidy, D., Kerr, B., Land, S. C. & Mehta, A., 29 Feb 2016, In : PLoS ONE. 11, 2, 20 p., e0149550.

Research output: Contribution to journalArticle

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8 Citations (Scopus)
281 Downloads (Pure)
2015

An investigation of causes of false positive single nucleotide polymorphisms using simulated reads from a small eukaryote genome

Ribeiro, A., Golicz, A., Hackett, C. A., Milne, I., Stephen, G., Marshall, D., Flavell, A. J. & Bayer, M., 11 Nov 2015, In : BMC Bioinformatics. 16, 1, p. 1-16 16 p., 382.

Research output: Contribution to journalArticle

Open Access
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18 Citations (Scopus)
95 Downloads (Pure)

Multimode fibre: Light-sheet microscopy at the tip of a needle

Plöschner, M., Kollarova, V., Dostal, Z., Nylk, J., Barton-Owen, T., Ferrier, D. E. K., Chmelik, R., Dholakia, K. & Cizmar, T., 14 Dec 2015, In : Scientific Reports. 5, p. 1-7 7 p., 18050.

Research output: Contribution to journalArticle

Open Access
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23 Citations (Scopus)
146 Downloads (Pure)

Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

Wongpaiboonwattana, W. & Stavridis, M. P., 14 May 2015, In : JoVE: Journal of Visualized Experiments. 99, e52823.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
159 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors

Alexander, S. P. H., Fabbro, D., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5979-6023 45 p.

Research output: Contribution to journalArticle

Open Access
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145 Citations (Scopus)
141 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Transporters

Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 6110-6202 93 p.

Research output: Contribution to journalArticle

Open Access
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199 Citations (Scopus)
148 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Ligand-gated ion channels

Alexander, S. P. H., Peters, J. A., Kelly, E., Marrion, N., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5870-5903 34 p.

Research output: Contribution to journalArticle

Open Access
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111 Citations (Scopus)
73 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels

Alexander, S. P. H., Catterall, W. A., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & and CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5904-5941 38 p.

Research output: Contribution to journalArticle

Open Access
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162 Citations (Scopus)
115 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors

Alexander, S. P. H., Cidlowski, J. A., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5956-5978 23 p.

Research output: Contribution to journalArticle

Open Access
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111 Citations (Scopus)
53 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

Alexander, S. P. H., Fabbro, D., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 6024-6109 86 p.

Research output: Contribution to journalArticle

Open Access
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512 Citations (Scopus)
119 Downloads (Pure)

The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels

Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5942-5955 14 p.

Research output: Contribution to journalArticle

Open Access
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33 Citations (Scopus)
106 Downloads (Pure)

THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: G protein-coupled receptors

Alexander, S. P. H., Davenport, A. P., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A. & CGTP Collaborators, Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5744-5869 126 p.

Research output: Contribution to journalArticle

Open Access
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457 Citations (Scopus)
322 Downloads (Pure)
2014

mTOR signalling, embryogenesis and the control of lung development

Land, S. C., Scott, C. L. & Walker, D., 2014, In : Seminars in Cell & Developmental Biology. 36, p. 68-78 11 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
113 Downloads (Pure)

Role of amino acid transporters in amino acid sensing

Taylor, P. M., Jan 2014, In : American Journal of Clinical Nutrition. 99, 1, p. 2235-2305 71 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)
2013

Birt-Hogg-Dubé syndrome is a novel ciliopathy

Luijten, M. N. H., Basten, S. G., Claessens, T., Vernooij, M., Scott, C. L., Janssen, R., Easton, J. A., Kamps, M. A. F., Vreeburg, M., Broers, J. L. V., van Geel, M., Menko, F. H., Harbottle, R. P., Nookala, R. K., Tee, A. R., Land, S. C., Giles, R. H., Coull, B. J. & van Steensel, M., 2013, In : Human Molecular Genetics. 22, 21, p. 4383-4397 15 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Resistance gene enrichment sequencing (RenSeq) enables reannotation of the NB-LRR gene family from sequenced plant genomes and rapid mapping of resistance loci in segregating populations

Jupe, F., Witek, K., Verweij, W., Śliwka, J., Pritchard, L., Etherington, G. J., Maclean, D., Cock, P. J., Leggett, R. M., Bryan, G. J., Cardle, L., Hein, I. & Jones, J. D. G., 1 Nov 2013, In : Plant Journal. 76, 3, p. 530-544 15 p.

Research output: Contribution to journalArticle

Open Access
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131 Citations (Scopus)
104 Downloads (Pure)
2012

Genome-wide association mapping of agronomic and morphologic traits in highly structured populations of barley cultivars

Wang, M., Jiang, N., Jia, T., Leach, L., Cockram, J., Waugh, R., Ramsay, L., Thomas, B. & Luo, Z., 1 Jan 2012, In : Theoretical and Applied Genetics. 124, 2, p. 233-246 14 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Gigsaw: physical simulation of next-generation sequencing for education and outreach

Martin, D., Jun 2012, In : EMBnet Journal. 18, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

2011

Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

Preston, R. S., Philp, A., Claessens, T., Gijezen, L., Dydensborg, A. B., Dunlop, E. A., Harper, K. T., Brinkhuizen, T., Menko, F. H., Davies, D. M., Land, S. C., Pause, A., Baar, K., van Steensel, M. & Tee, A. R., 2011, In : Oncogene. 30, 10, p. 1159-1173 15 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Genome sequence and analysis of the tuber crop potato

The Potato Genome Sequencing Consortium, 14 Jul 2011, In : Nature. 475, 7355, p. 189-195 7 p.

Research output: Contribution to journalArticle

Open Access
1055 Citations (Scopus)

Patterns of polymorphism and linkage disequilibrium in cultivated barley

Comadran, J., Ramsay, L., MacKenzie, K., Hayes, P., Close, T. J., Muehlbauer, G., Stein, N. & Waugh, R., 1 Feb 2011, In : Theoretical and Applied Genetics. 122, 3, p. 523-531 9 p.

Research output: Contribution to journalArticle

Open Access
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30 Citations (Scopus)
96 Downloads (Pure)
2010

An eQTL analysis of partial resistance to Puccinia hordei in barley

Chen, X., Hackett, C. A., Niks, R. E., Hedley, P. E., Booth, C., Druka, A., Marcel, T. C., Vels, A., Bayer, M., Milne, I., Morris, J., Ramsay, L., Marshall, D., Cardle, L. & Waugh, R., 6 Jan 2010, In : PLoS ONE. 5, 1, e8598.

Research output: Contribution to journalArticle

Open Access
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56 Citations (Scopus)
92 Downloads (Pure)

Development of a molecular cytogenetic recombination assay for barley

Phillips, D., Nibau, C., Ramsay, L., Waugh, R. & Jenkins, G., 1 Jul 2010, In : Cytogenetic and Genome Research. 129, 1-3, p. 154-161 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Evaluation for computational platforms of LC-MS based label-free quantitative proteomics: A global view

Zhang, R., Barton, A., Brittenden, J., Huang, J. T. -J. & Crowther, D., 19 Nov 2010, In : Journal of Proteomics and Bioinformatics. 3, 9, p. 260-265 6 p.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
121 Downloads (Pure)
182 Citations (Scopus)
2009

Development and implementation of high-throughput SNP genotyping in barley

Close, T. J., Bhat, P. R., Lonardi, S., Wu, Y., Rostoks, N., Ramsay, L., Druka, A., Stein, N., Svensson, J. T., Wanamaker, S., Bozdag, S., Roose, M. L., Moscou, M. J., Chao, S., Varshney, R. K., Szucs, P., Sato, K., Hayes, P. M., Matthews, D. E., Kleinhofs, A. & 8 others, Muehlbauer, G. J., DeYoung, J., Marshall, D. F., Madishetty, K., Fenton, R. D., Condamine, P., Graner, A. & Waugh, R., 4 Dec 2009, In : BMC Genomics. 10, 582.

Research output: Contribution to journalArticle

Open Access
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436 Citations (Scopus)
99 Downloads (Pure)

Identification of nucleolar associated chromatin loci reveals clues for nuclear architecture

van Koningsbruggen, S., Martin, D. M. A., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I., 2009, In : Cellular Oncology. 31, 2, p. 105-106 2 p., O16.

Research output: Contribution to journalArticle

2007

A high density barley microsatellite consensus map with 775 SSR loci

Varshney, R. K., Marcel, T. C., Ramsay, L., Russell, J., Röder, M. S., Stein, N., Waugh, R., Langridge, P., Niks, R. E. & Graner, A., 1 Apr 2007, In : Theoretical and Applied Genetics. 114, 6, p. 1091-1103 13 p.

Research output: Contribution to journalArticle

226 Citations (Scopus)

A novel non-protein-coding infection-specific gene family is clustered throughout the genome of Phytophthora infestans

Avrova, A. O., Whisson, S. C., Pritchard, L., Venter, E., De Luca, S., Hein, I. & Birch, P. R. J., 1 Mar 2007, In : Microbiology. 153, Pt 3, p. 747-759 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Draft genome of the filarial nematode parasite Brugia malayi

Ghedin, E., Wang, S., Spiro, D., Caler, E., Zhao, Q., Crabtree, J., Allen, J. E., Delcher, A. L., Guiliano, D. B., Miranda-Saavedra, D., Angiuoli, S. V., Creasy, T., Amedeo, P., Haas, B., El-Sayed, N. M., Wortman, J. R., Feldblyum, T., Tallon, L., Schatz, M., Shumway, M. & 51 others, Koo, H., Salzberg, S. L., Schobel, S., Pertea, M., Pop, M., White, O., Barton, G. J., Carlow, C. K. S., Crawford, M. J., Daub, J., Dimmic, M. W., Estes, C. F., Foster, J. M., Ganatra, M., Gregory, W. F., Johnson, N. M., Jin, J., Komuniecki, R., Korf, I., Kumar, S., Laney, S., Li, B-W., Li, W., Lindblom, T. H., Lustigman, S., Ma, D., Maina, C. V., Martin, D. M. A., McCarter, J. P., McReynolds, L., Mitreva, M., Nutman, T. B., Parkinson, J., Peregrín-Alvarez, J. M., Poole, C., Ren, Q., Saunders, L., Sluder, A. E., Smith, K., Stanke, M., Unnasch, T. R., Ware, J., Wei, A. D., Weil, G., Williams, D. J., Zhang, Y., Williams, S. A., Fraser-Liggett, C., Slatko, B., Blaxter, M. L. & Scott, A. L., 21 Sep 2007, In : Science. 317, 5845, p. 1756-1760 5 p.

Research output: Contribution to journalArticle

464 Citations (Scopus)
2006

Novel structural determinants of the single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors

Peters, J. A., Carland, J. E., Cooper, M. A., Livesey, M. R., Deeb, T. Z., Hales, T. G. & Lambert, J. J., 1 Oct 2006, In : Biochemical Society Transactions. 34, 5, p. 882-886 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Recent history of artificial outcrossing facilitates whole-genome association mapping in elite inbred crop varietes

Rostoks, N., Ramsay, L., MacKenzie, K., Cardle, L., Bhat, P. R., Roose, M. L., Svensson, J. T., Stein, N., Varshney, R. K., Marshall, D. F., Graner, A., Close, T. J. & Waugh, R., 5 Dec 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 49, p. 18656-18661 6 p.

Research output: Contribution to journalArticle

244 Citations (Scopus)
2005

A comparative analysis of transcript abundance using SAGE and Affymetrix arrays

Ibrahim, A. F. M., Hedley, P. E., Cardle, L., Kruger, W., Marshall, D. F., Muehlbauer, G. J. & Waugh, R., 1 Jul 2005, In : Functional and Integrative Genomics. 5, 3, p. 163-174 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
3 Citations (Scopus)

Characterisation and functional analysis of two barley caleosins expressed during barley caryopsis development

Liu, H., Hedley, P., Cardle, L., Wright, K. M., Hein, I., Marshall, D. & Waugh, R., 1 Jun 2005, In : Planta. 221, 4, p. 513-522 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Genome-wide SNP discovery and linkage analysis in barley based on genes responsive to abiotic stress

Rostoks, N., Mudie, S., Cardle, L., Russell, J., Ramsay, L., Booth, A., Svensson, J. T., Wanamaker, S. I., Walia, H., Rodriguez, E. M., Hedley, P. E., Liu, H., Morris, J., Close, T. J., Marshall, D. F. & Waugh, R., 1 Dec 2005, In : Molecular Genetics and Genomics. 274, 5, p. 515-527 13 p.

Research output: Contribution to journalArticle

219 Citations (Scopus)

Isolation of high molecular weight DNA suitable for BAC library construction from woody perennial soft-fruit species

Hein, I., Williamson, S., Russell, J. & Powell, W., Jan 2005, In : BioTechniques. 38, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Retrotransposon populations of Vicia species with varying genome size.

Martin, D., Flavell, A., Hill, P. & Burford, D., Jun 2005, In : Molecular Genetics and Genomics. 273, 5, p. 371-81 11 p.

Research output: Contribution to journalArticle

Open Access
43 Citations (Scopus)

Single-feature polymorphism discovery in the barley transcriptome.

Rostoks, N., Borevitz, J. O., Hedley, P. E., Russell, J., Mudie, S., Morris, J., Cardle, L., Marshall, D. F. & Waugh, R., 1 Dec 2005, In : Genome Biology. 6, 6, 10 p., R54.

Research output: Contribution to journalArticle

Open Access
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119 Citations (Scopus)
11 Downloads (Pure)
2004

A barley cultivation-associated polymorphism conveys resistance to powdery mildew

Piffanelli, P., Ramsay, L., Waugh, R., Benabdelmouna, A., D'Hont, A., Hollricher, K., Jørgensen, J. H., Schulze-Lefert, P. & Panstruga, R., 19 Aug 2004, In : Nature. 430, 7002, p. 887-891 5 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

A structured mutant population for forward and reverse genetics in Barley (Hordeum vulgare L.)

Caldwell, D. G., McCallum, N., Shaw, P., Muehlbauer, G. J., Marshall, D. F. & Waugh, R., 1 Oct 2004, In : Plant Journal. 40, 1, p. 143-150 8 p.

Research output: Contribution to journalArticle

226 Citations (Scopus)

Characterisation of early transcriptional changes involving multiple signalling pathways in the Mla13 barley interaction with powdery mildew (Blumeria graminis f. sp. hordei)

Hein, I., Campbell, E. I., Woodhead, M., Hedley, P. E., Young, V., Morris, W. L., Ramsay, L., Stockhaus, J., Lyon, G. D., Newton, A. C. & Birch, P. R. J., Mar 2004, In : Planta. 218, 5, p. 803-813 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Characterization of the ligand binding site of the bovine IgA Fc receptor (bFcαR)

Morton, H. C., Pleass, R. J., Woof, J. M. & Brandtzaeg, P., 24 Dec 2004, In : Journal of Biological Chemistry. 279, 52, p. 54018-54022 5 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
56 Downloads (Pure)

Cloning and characterization of an immunoglobulin A Fc receptor from cattle

Morton, H. C., Pleass, R. J., Storset, A. K., Dissen, E., Williams, J. L., Brandtzaeg, P. & Woof, J. M., Feb 2004, In : Immunology. 111, 2, p. 204-211 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Comparison of RAMP and SSR markers for the study of wild barley genetic diversity

Dávila, J. A., Loarce, Y., Ramsay, L., Waugh, R. & Ferrer, E., 6 May 2004, In : Hereditas. 131, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes

Martin, D. M. A., Berriman, M. & Barton, G. J., 18 Nov 2004, In : BMC Bioinformatics. 5, 17 p., 178.

Research output: Contribution to journalArticle

Open Access
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183 Citations (Scopus)
48 Downloads (Pure)

Potato oxysterol binding protein and cathepsin B are rapidly up-regulated in independent defence pathways that distinguish R gene-mediated and field resistances to Phytophthora infestans

Avrova, A. O., Taleb, N., Rokka, V-M., Heilbronn, J., Campbell, E., Hein, I., Gilroy, E. M., Cardle, L., Bradshaw, J. E., Stewart, H. E., Fakim, Y. J., Loake, G. & Birch, P. R. J., 16 Jan 2004, In : Molecular Plant Pathology. 5, 1, p. 45-56 12 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Potato virus X-induced gene silencing in leaves and tubers of potato

Faivre-Rampant, O., Gilroy, E. M., Hrubikova, K., Hein, I., Millam, S., Loake, G. J., Birch, P., Taylor, M. & Lacomme, C., Apr 2004, In : Plant Physiology. 134, 4, p. 1308-1316 9 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance

Peters, J. A., Kelley, S. P., Dunlop, J. I., Kirkness, E. F., Hales, T. G. & Lambert, J. J., 1 Jun 2004, In : Biochemical Society Transactions. 32, 3, p. 547-552 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors

Weir, C. J., Ling, A. T. Y., Belelli, D., Wildsmith, J. A. W., Peters, J. A. & Lambert, J. J., May 2004, In : British journal of anaesthesia. 92, 5, p. 704-711 8 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)