DArcy Thompson Unit

Research Output 1987 2020

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Article
2011
29 Citations (Scopus)
49 Downloads (Pure)

Patterns of polymorphism and linkage disequilibrium in cultivated barley

Comadran, J., Ramsay, L., MacKenzie, K., Hayes, P., Close, T. J., Muehlbauer, G., Stein, N. & Waugh, R., 1 Feb 2011, In : Theoretical and Applied Genetics. 122, 3, p. 523-531 9 p.

Research output: Contribution to journalArticle

Open Access
File
Linkage Disequilibrium
Hordeum
linkage disequilibrium
barley
genetic polymorphism
2010
54 Citations (Scopus)
44 Downloads (Pure)

An eQTL analysis of partial resistance to Puccinia hordei in barley

Chen, X., Hackett, C. A., Niks, R. E., Hedley, P. E., Booth, C., Druka, A., Marcel, T. C., Vels, A., Bayer, M., Milne, I., Morris, J., Ramsay, L., Marshall, D., Cardle, L. & Waugh, R., 6 Jan 2010, In : PLoS ONE. 5, 1, e8598.

Research output: Contribution to journalArticle

Open Access
File
Puccinia hordei
Quantitative Trait Loci
Hordeum
quantitative trait loci
Genes
15 Citations (Scopus)

Development of a molecular cytogenetic recombination assay for barley

Phillips, D., Nibau, C., Ramsay, L., Waugh, R. & Jenkins, G., 1 Jul 2010, In : Cytogenetic and Genome Research. 129, 1-3, p. 154-161 8 p.

Research output: Contribution to journalArticle

Hordeum
Cytogenetics
Genetic Recombination
Bacterial Artificial Chromosomes
Synaptonemal Complex
19 Citations (Scopus)
62 Downloads (Pure)

Evaluation for computational platforms of LC-MS based label-free quantitative proteomics: A global view

Zhang, R., Barton, A., Brittenden, J., Huang, J. T. -J. & Crowther, D., 19 Nov 2010, In : Journal of Proteomics and Bioinformatics. 3, 9, p. 260-265 6 p.

Research output: Contribution to journalArticle

Open Access
File
Proteomics
Labels
Software
Proteins
Benchmarking
175 Citations (Scopus)
Anthocyanins
Genome-Wide Association Study
Hordeum
Genome
Helix-Loop-Helix Motifs
2009
420 Citations (Scopus)
48 Downloads (Pure)

Development and implementation of high-throughput SNP genotyping in barley

Close, T. J., Bhat, P. R., Lonardi, S., Wu, Y., Rostoks, N., Ramsay, L., Druka, A., Stein, N., Svensson, J. T., Wanamaker, S., Bozdag, S., Roose, M. L., Moscou, M. J., Chao, S., Varshney, R. K., Szucs, P., Sato, K., Hayes, P. M., Matthews, D. E., Kleinhofs, A. & 8 others, Muehlbauer, G. J., DeYoung, J., Marshall, D. F., Madishetty, K., Fenton, R. D., Condamine, P., Graner, A. & Waugh, R., 4 Dec 2009, In : BMC Genomics. 10, 582.

Research output: Contribution to journalArticle

Open Access
File
Hordeum
Single Nucleotide Polymorphism
Gene Frequency
Breeding
Genome
2007
224 Citations (Scopus)

A high density barley microsatellite consensus map with 775 SSR loci

Varshney, R. K., Marcel, T. C., Ramsay, L., Russell, J., Röder, M. S., Stein, N., Waugh, R., Langridge, P., Niks, R. E. & Graner, A., 1 Apr 2007, In : Theoretical and Applied Genetics. 114, 6, p. 1091-1103 13 p.

Research output: Contribution to journalArticle

Hordeum
Microsatellite Repeats
barley
microsatellite repeats
loci
23 Citations (Scopus)

A novel non-protein-coding infection-specific gene family is clustered throughout the genome of Phytophthora infestans

Avrova, A. O., Whisson, S. C., Pritchard, L., Venter, E., De Luca, S., Hein, I. & Birch, P. R. J., 1 Mar 2007, In : Microbiology. 153, Pt 3, p. 747-759 13 p.

Research output: Contribution to journalArticle

Phytophthora infestans
Genome
Infection
Complementary DNA
Genes
455 Citations (Scopus)

Draft genome of the filarial nematode parasite Brugia malayi

Ghedin, E., Wang, S., Spiro, D., Caler, E., Zhao, Q., Crabtree, J., Allen, J. E., Delcher, A. L., Guiliano, D. B., Miranda-Saavedra, D., Angiuoli, S. V., Creasy, T., Amedeo, P., Haas, B., El-Sayed, N. M., Wortman, J. R., Feldblyum, T., Tallon, L., Schatz, M., Shumway, M. & 51 others, Koo, H., Salzberg, S. L., Schobel, S., Pertea, M., Pop, M., White, O., Barton, G. J., Carlow, C. K. S., Crawford, M. J., Daub, J., Dimmic, M. W., Estes, C. F., Foster, J. M., Ganatra, M., Gregory, W. F., Johnson, N. M., Jin, J., Komuniecki, R., Korf, I., Kumar, S., Laney, S., Li, B-W., Li, W., Lindblom, T. H., Lustigman, S., Ma, D., Maina, C. V., Martin, D. M. A., McCarter, J. P., McReynolds, L., Mitreva, M., Nutman, T. B., Parkinson, J., Peregrín-Alvarez, J. M., Poole, C., Ren, Q., Saunders, L., Sluder, A. E., Smith, K., Stanke, M., Unnasch, T. R., Ware, J., Wei, A. D., Weil, G., Williams, D. J., Zhang, Y., Williams, S. A., Fraser-Liggett, C., Slatko, B., Blaxter, M. L. & Scott, A. L., 21 Sep 2007, In : Science. 317, 5845, p. 1756-1760 5 p.

Research output: Contribution to journalArticle

Brugia malayi
Parasites
Ocular Onchocerciasis
Elephantiasis
Genome
2006
10 Citations (Scopus)

Novel structural determinants of the single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors

Peters, J. A., Carland, J. E., Cooper, M. A., Livesey, M. R., Deeb, T. Z., Hales, T. G. & Lambert, J. J., 1 Oct 2006, In : Biochemical Society Transactions. 34, 5, p. 882-886 5 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Nicotinic Receptors
Ion Channels
Acetylcholine
Torpedo
241 Citations (Scopus)

Recent history of artificial outcrossing facilitates whole-genome association mapping in elite inbred crop varietes

Rostoks, N., Ramsay, L., MacKenzie, K., Cardle, L., Bhat, P. R., Roose, M. L., Svensson, J. T., Stein, N., Varshney, R. K., Marshall, D. F., Graner, A., Close, T. J. & Waugh, R., 5 Dec 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 49, p. 18656-18661 6 p.

Research output: Contribution to journalArticle

Chromosome Mapping
Linkage Disequilibrium
Single Nucleotide Polymorphism
Genome
Population
2005
33 Citations (Scopus)

A comparative analysis of transcript abundance using SAGE and Affymetrix arrays

Ibrahim, A. F. M., Hedley, P. E., Cardle, L., Kruger, W., Marshall, D. F., Muehlbauer, G. J. & Waugh, R., 1 Jul 2005, In : Functional and Integrative Genomics. 5, 3, p. 163-174 12 p.

Research output: Contribution to journalArticle

Gene Expression
Gene Expression Profiling
Hordeum
Libraries
Embryonic Structures
19 Citations (Scopus)

Characterisation and functional analysis of two barley caleosins expressed during barley caryopsis development

Liu, H., Hedley, P., Cardle, L., Wright, K. M., Hein, I., Marshall, D. & Waugh, R., 1 Jun 2005, In : Planta. 221, 4, p. 513-522 10 p.

Research output: Contribution to journalArticle

lipid bodies
Hordeum
barley
body protein
fruits
219 Citations (Scopus)

Genome-wide SNP discovery and linkage analysis in barley based on genes responsive to abiotic stress

Rostoks, N., Mudie, S., Cardle, L., Russell, J., Ramsay, L., Booth, A., Svensson, J. T., Wanamaker, S. I., Walia, H., Rodriguez, E. M., Hedley, P. E., Liu, H., Morris, J., Close, T. J., Marshall, D. F. & Waugh, R., 1 Dec 2005, In : Molecular Genetics and Genomics. 274, 5, p. 515-527 13 p.

Research output: Contribution to journalArticle

Hordeum
Single Nucleotide Polymorphism
Genome
Genes
Gene Order
13 Citations (Scopus)

Isolation of high molecular weight DNA suitable for BAC library construction from woody perennial soft-fruit species

Hein, I., Williamson, S., Russell, J. & Powell, W., Jan 2005, In : BioTechniques. 38, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Bacterial DNA
Chromosomes
Fruits
Fruit
119 Citations (Scopus)
6 Downloads (Pure)

Single-feature polymorphism discovery in the barley transcriptome.

Rostoks, N., Borevitz, J. O., Hedley, P. E., Russell, J., Mudie, S., Morris, J., Cardle, L., Marshall, D. F. & Waugh, R., 1 Dec 2005, In : Genome Biology. 6, 6, 10 p., R54.

Research output: Contribution to journalArticle

Open Access
File
Hordeum
Transcriptome
transcriptome
barley
single nucleotide polymorphism
2004
118 Citations (Scopus)

A barley cultivation-associated polymorphism conveys resistance to powdery mildew

Piffanelli, P., Ramsay, L., Waugh, R., Benabdelmouna, A., D'Hont, A., Hollricher, K., Jørgensen, J. H., Schulze-Lefert, P. & Panstruga, R., 19 Aug 2004, In : Nature. 430, 7002, p. 887-891 5 p.

Research output: Contribution to journalArticle

Hordeum
Alleles
Tandem Repeat Sequences
Disease Resistance
Agriculture
216 Citations (Scopus)

A structured mutant population for forward and reverse genetics in Barley (Hordeum vulgare L.)

Caldwell, D. G., McCallum, N., Shaw, P., Muehlbauer, G. J., Marshall, D. F. & Waugh, R., 1 Oct 2004, In : Plant Journal. 40, 1, p. 143-150 8 p.

Research output: Contribution to journalArticle

Reverse Genetics
Population Genetics
Hordeum
Hordeum vulgare
barley
22 Citations (Scopus)

Characterisation of early transcriptional changes involving multiple signalling pathways in the Mla13 barley interaction with powdery mildew (Blumeria graminis f. sp. hordei)

Hein, I., Campbell, E. I., Woodhead, M., Hedley, P. E., Young, V., Morris, W. L., Ramsay, L., Stockhaus, J., Lyon, G. D., Newton, A. C. & Birch, P. R. J., Mar 2004, In : Planta. 218, 5, p. 803-813 11 p.

Research output: Contribution to journalArticle

Blumeria graminis f. sp. hordei
Hordeum
powdery mildew
Salicylic Acid
barley
4 Citations (Scopus)
13 Downloads (Pure)

Characterization of the ligand binding site of the bovine IgA Fc receptor (bFcαR)

Morton, H. C., Pleass, R. J., Woof, J. M. & Brandtzaeg, P., 24 Dec 2004, In : Journal of Biological Chemistry. 279, 52, p. 54018-54022 5 p.

Research output: Contribution to journalArticle

Open Access
File
Fc Receptors
Immunoglobulin A
Binding Sites
Ligands
Mutation
20 Citations (Scopus)

Cloning and characterization of an immunoglobulin A Fc receptor from cattle

Morton, H. C., Pleass, R. J., Storset, A. K., Dissen, E., Williams, J. L., Brandtzaeg, P. & Woof, J. M., Feb 2004, In : Immunology. 111, 2, p. 204-211 8 p.

Research output: Contribution to journalArticle

Fc Receptors
Immunoglobulin A
Organism Cloning
Complementary DNA
Immunoglobulin G
42 Citations (Scopus)

Comparison of RAMP and SSR markers for the study of wild barley genetic diversity

Dávila, J. A., Loarce, Y., Ramsay, L., Waugh, R. & Ferrer, E., 6 May 2004, In : Hereditas. 131, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

Hordeum
Microsatellite Repeats
Genotype
Technology
181 Citations (Scopus)
19 Downloads (Pure)

GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes

Martin, D. M. A., Berriman, M. & Barton, G. J., 18 Nov 2004, In : BMC Bioinformatics. 5, 17 p., 178.

Research output: Contribution to journalArticle

Open Access
File
Gene Ontology
Annotation
Genome
Genes
Proteins
46 Citations (Scopus)

Potato oxysterol binding protein and cathepsin B are rapidly up-regulated in independent defence pathways that distinguish R gene-mediated and field resistances to Phytophthora infestans

Avrova, A. O., Taleb, N., Rokka, V-M., Heilbronn, J., Campbell, E., Hein, I., Gilroy, E. M., Cardle, L., Bradshaw, J. E., Stewart, H. E., Fakim, Y. J., Loake, G. & Birch, P. R. J., 16 Jan 2004, In : Molecular Plant Pathology. 5, 1, p. 45-56 12 p.

Research output: Contribution to journalArticle

Phytophthora infestans
potato protein
vpr Genes
cathepsin B
Cathepsin B
107 Citations (Scopus)

Potato virus X-induced gene silencing in leaves and tubers of potato

Faivre-Rampant, O., Gilroy, E. M., Hrubikova, K., Hein, I., Millam, S., Loake, G. J., Birch, P., Taylor, M. & Lacomme, C., Apr 2004, In : Plant Physiology. 134, 4, p. 1308-1316 9 p.

Research output: Contribution to journalArticle

Potexvirus
Potato virus X
Gene Silencing
gene silencing
Solanum tuberosum
24 Citations (Scopus)

The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance

Peters, J. A., Kelley, S. P., Dunlop, J. I., Kirkness, E. F., Hales, T. G. & Lambert, J. J., 1 Jun 2004, In : Biochemical Society Transactions. 32, 3, p. 547-552 6 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Ion Channels
Serotonin
Nicotinic Receptors
Cations
55 Citations (Scopus)

The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors

Weir, C. J., Ling, A. T. Y., Belelli, D., Wildsmith, J. A. W., Peters, J. A. & Lambert, J. J., May 2004, In : British journal of anaesthesia. 92, 5, p. 704-711 8 p.

Research output: Contribution to journalArticle

Glycine Receptors
GABA-A Receptors
Anesthetics
Steroids
Glycine
2003
6 Citations (Scopus)

GABAA receptor modulation by the novel intravenous general anaesthetic E-6375

Pau, D., Belelli, D., Callachan, H., Peden, D. R., Dunlop, J. I., Peters, J. A., Guitart, X., Gutierrez, B. & Lambert, J. J., Dec 2003, In : Neuropharmacology. 45, 8, p. 1029-1040 12 p.

Research output: Contribution to journalArticle

Intravenous Anesthetics
General Anesthetics
GABA-A Receptors
gamma-Aminobutyric Acid
Anesthetics
1 Citation (Scopus)

Visual representation of database search results: the RHIMS Plot

Martin, D. M. A., Hill, P., Barton, G. J. & Flavell, A. J., 22 May 2003, In : Bioinformatics. 19, 8, p. 1037-1038 2 p.

Research output: Contribution to journalArticle

Servers
Software
Visualization
Databases
Data Mining
2002
51 Citations (Scopus)
Amiloride
Biosynthesis
Amplification
Lipopolysaccharides
Anti-Inflammatory Agents
77 Citations (Scopus)
Alveolar Epithelial Cells
Phosphoric Diester Hydrolases
Lipopolysaccharides
Interleukin-6
Tumor Necrosis Factor-alpha
53 Citations (Scopus)

Immunopharmacological Potential of Selective Phosphodiesterase Inhibition. II. Evidence for the Involvement of an Inhibitory-κB/Nuclear Factor-κB-Sensitive Pathway in Alveolar Epithelial Cells

Haddad, J. J., Land, S. C., Tarnow-Mordi, W. O., Zembala, M., Kowalczyk, D. & Lauterbach, R., 1 Feb 2002, In : Journal of Pharmacology and Experimental Therapeutics. 300, 2, p. 567-576 10 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Phosphoric Diester Hydrolases
Endotoxins
Pentoxifylline
Lipopolysaccharides
52 Citations (Scopus)

Isolation and detection of human IgA using a streptococcal IgA-binding peptide

Sandin, C., Linse, S., Areschoug, T., Woof, J. M., Reinholdt, J. & Lindahl, G., 1 Aug 2002, In : Journal of Immunology. 169, 3, p. 1357-1364 8 p.

Research output: Contribution to journalArticle

Immunoglobulin A
Peptides
Secretory Immunoglobulin A
Bacterial Proteins
Allergy and Immunology
119 Citations (Scopus)
Mitogen-Activated Protein Kinases
Oxidation-Reduction
Lipopolysaccharides
Phosphorylation
Acetylcysteine
34 Citations (Scopus)
Alveolar Epithelial Cells
Biosynthesis
Oxidation-Reduction
Lipopolysaccharides
Phosphorylation
25 Citations (Scopus)

Sample sequencing of a selected region of the genome of Erwinia carotovora subsp. atroseptica reveals candidate phytopathogenicity genes and allows comparison with Escherichia coli

Bell, K. S., Avrova, A. O., Holeva, M. C., Cardle, L., Morris, W., De Jong, W., Toth, I. K., Waugh, R., Bryan, G. J. & Birch, P. R. J., 1 Jan 2002, In : Microbiology. 148, 5, p. 1367-1378 12 p.

Research output: Contribution to journalArticle

Pectobacterium carotovorum
Bacterial Artificial Chromosomes
Genome
Escherichia coli
Erwinia amylovora
2001
204 Citations (Scopus)

A non-hypoxic, ROS-sensitive pathway mediates TNF-α-dependent regulation of HIF-1α

Haddad, J. J. & Land, S. C., 14 Sep 2001, In : FEBS Letters. 505, 2, p. 269-274 6 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Reactive Oxygen Species
Tumor Necrosis Factor-alpha
Chemical activation
Mitochondria
98 Citations (Scopus)

A representative, highly informative 'genotyping set' of barley SSRs

Macaulay, M., Ramsay, L., Powell, W. & Waugh, R., 26 Jun 2001, In : Theoretical and Applied Genetics. 102, 6-7, p. 801-809 9 p.

Research output: Contribution to journalArticle

Hordeum
genotyping
barley
Genotype
genotype
68 Citations (Scopus)

Chemioxyexcitation (ΔpO2/ROS)-dependent release of IL-1β, IL-6 and TNF-α: Evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium

Haddad, J. J. E., Safieh-Garabedian, B., Saadé, N. E., Kanaan, S. A. & Land, S. C., 7 Feb 2001, In : Cytokine. 13, 3, p. 138-147 10 p.

Research output: Contribution to journalArticle

Interleukin-1
Interleukin-6
Reactive Oxygen Species
Epithelium
Cytokines
38 Citations (Scopus)

Neurosteroid modulation of recombinant and synaptic GABAA receptors

Lambert, J., Harney, S. C., Belelli, D. & Peters, J. A., 2001, In : International Review of Neurobiology. 46, p. 177-205 29 p.

Research output: Contribution to journalArticle

Neurotransmitter Receptor
GABA-A Receptors
Neurotransmitter Agents
Steroids
Pregnanes
21 Citations (Scopus)

NF-κB blockade reduces the O2-evoked rise in Na+ conductance in fetal alveolar cells

Haddad, J. J. E., Collett, A., Land, S. C., Olver, R. E. & Wilson, S. M., 9 Mar 2001, In : Biochemical and Biophysical Research Communications. 281, 4, p. 987-992 6 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Sulfasalazine
Chemical activation
Electrophoretic mobility
Rats
19 Citations (Scopus)
Alveolar Epithelial Cells
Biosynthesis
Lipopolysaccharides
Tumor Necrosis Factor-alpha
Sulfasalazine
50 Citations (Scopus)

Physical mapping across an avirulence iocus of phytophthora infestans using a highly representative, large-insert bacterial artificial chromosome library

Whisson, S. C., Van Der Lee, T., Bryan, G. J., Waugh, R., Govers, F. & Birch, P. R. J., 16 Oct 2001, In : Molecular Genetics and Genomics. 266, 2, p. 289-295 7 p.

Research output: Contribution to journalArticle

Phytophthora infestans
Bacterial Artificial Chromosomes
Clone Cells
Oomycetes
Genes
85 Citations (Scopus)

Streptococcal IgA-binding Proteins Bind in the Cα2-Cα3 Interdomain Region and Inhibit Binding of IgA to Human CD89

Pleass, R. J., Areschoug, T., Lindahl, G. & Woof, J. M., 16 Mar 2001, In : Journal of Biological Chemistry. 276, 11, p. 8197-8204 8 p.

Research output: Contribution to journalArticle

Open Access
Immunoglobulin A
Carrier Proteins
Proteins
Bacterial Proteins
Respiratory Burst
25 Citations (Scopus)

The biphasic immunoregulation of pyrimidylpiperazine (Y-40138) is IL-10 sensitive and requires NF-κB targeting in the alveolar epithelium

Haddad, J. J. E., Safieh-Garabedian, B., Saadé, N. E. & Land, S. C., May 2001, In : British Journal of Pharmacology. 133, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

Interleukin-10
Epithelium
Anti-Inflammatory Agents
Cytokines
Interleukin-1
20 Citations (Scopus)
Oxygenation
Respiration
Apoptosis
Lung
Proto-Oncogenes
72 Citations (Scopus)

Thiol Regulation of Pro-Inflammatory Cytokines Reveals a Novel Immunopharmacological Potential of Glutathione in the Alveolar Epithelium

Haddad, J. J. E., Safieh-Garabedian, B., Saadé, N. E. & Land, S. C., 1 Mar 2001, In : Journal of Pharmacology and Experimental Therapeutics. 296, 3, p. 996-1005 10 p.

Research output: Contribution to journalArticle

Sulfhydryl Compounds
Glutathione
Reactive Oxygen Species
Epithelium
Cytokines
19 Citations (Scopus)

α-amino acid phenolic ester derivatives: Novel water-soluble general anesthetic agents which allosterically modulate gabaa receptors

Anderson, A., Belelli, D., Bennett, J., Buchanan, K. I., Casula, A., Cooke, A., Feilden, H., Gemmell, D. K., Hamilton, N. M., Hutchinson, E. J., Lambert, J. J., Maidment, M. S., McGuire, R., McPhail, P., Miller, S., Muntoni, A., Peters, J. A., Sansbury, F. H., Stevenson, D. & Sundaramt, H., 25 Oct 2001, In : Journal of Medicinal Chemistry. 44, 22, p. 3582-3591 10 p.

Research output: Contribution to journalArticle

General Anesthetics
GABA-A Receptors
Anesthetics
Esters
Anesthesia
68 Citations (Scopus)
prolylvaline
Interleukins
Melanocytes
Endotoxins
Lipopolysaccharides
2000
222 Citations (Scopus)

Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1a and NF-kB Redox Sensitivity: EVIDENCE FOR INHIBITION BY GLUTATHIONE OXIDATION IN ALVEOLAR EPITHELIAL CELLS

Haddad, J. J. E., Olver, R. E. & Land, S. C., 14 Jul 2000, In : Journal of Biological Chemistry. 275, 28, p. 21130-21139 10 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Glutathione Disulfide
NF-kappa B
Oxidation-Reduction
Glutathione