Drug Discovery Unit

School of Life Sciences

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

Adams, Eleanor
- Drug Discovery Unit
Person: Research Postgraduate Student
Akwensi, Justice
- Drug Discovery Unit
Person: Research Postgraduate Student
Aucar, Maria
- Drug Discovery Unit - Senior Computational Chemist
Person: Research

6 Not started
23 Active
43 Finished

Enabling Cryptococcal Meningitis Drug Discovery: Development Of Cryptococcus Screening Cascade And Identification Of High Quality Starting Points For Drug Discovery (Joint with GSK Tres Cantos Open Lab Foundation)
De Rycker, M. & Gilbert, I.
16/01/23 → 15/01/25
Project: Research
Development of LRRK2 Type II Inhibitors to Understand Utility of these Compounds for the Treatment of Parkinson's Disease
Alessi, D., Davies, P., Gilbert, I., Gray, D. & Read, K.
1/01/23 → 31/12/23
Project: Research
Multiparameter Compound Optimisation by Deep Learning and Generative Models (Joint with MIT)
Gilbert, I. & Zuccotto, F.
Wellcome Trust
1/09/22 → 31/08/23
Project: Research

8329 Citations
49 h-index
296 Article
27 Review article
8 Comment/debate
7 Other contribution
More

Anti-trypanosomatid drug discovery: progress and challenges
De Rycker, M., Wyllie, S., Horn, D., Read, K. D. & Gilbert, I. H., 31 Jan 2023, In: Nature Reviews Microbiology. 21, p. 35-50 16 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
5 Citations (Scopus)

6 Downloads (Pure)
Peptidyl tRNA hydrolase is required for robust prolyl-tRNA turnover in mycobacterium tuberculosis
Tomasi, F. G., Schweber, J. T. P., Kimura, S., Zhu, J., Cleghorn, L. A. T., Davis, S. H., Green, S. R., Waldor, M. K. & Rubin, E. J., 28 Feb 2023, In: MBio. 14, 1, 13 p., e03469-22.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Downloads (Pure)
The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes
Makarov, A., Began, J., Mautone, I. C., Pinto, E., Ferguson, L., Zoltner, M., Zoll, S. & Field, M. C., Feb 2023, In: Microbial Cell. 10, 2, p. 18-35 18 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Downloads (Pure)

Supporting data for “A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market”
Brandon, A. (Creator), Antonides, L. (Creator), Riley, J. (Contributor), Epemolu, O. (Contributor), Read, K. (Creator) & McKenzie, C. (Creator), University of Dundee, Mar 2021
DOI: 10.15132/10000164
Dataset

File

The Brian Cox Prize for Excellence in Public Engagement with Research: Project of the Year
Bellany, Fiona (Recipient), Bell, Mark (Recipient), Caldwell, Nicola (Recipient), Davis, Susan (Recipient), Wheldon, Mary (Recipient), Floyd, Ali (Recipient), Dowers, Karen (Recipient) & Cocco, Mattia (Recipient), 15 Jan 2020
Prize: Prize (including medals and awards)

9 Other
6 Public engagement and outreach - public lecture/debate/seminar
5 Public engagement and outreach - festival/exhibition
3 Schools engagement
More

Tour of Life Sciences
Amy Cameron (Organiser), Ali Floyd (Presenter), Ailsa Mackintosh (Presenter), Paul Davies (Presenter), Selma Cabrita Gulyurtlu (Presenter), Elisa Garcia-Wilson (Presenter) & Sohini Chakraborti (Presenter)
28 Mar 2023
Activity: Other activity types › Other
Life Sciences Work Experience Week 2022
Erin Hardee (Organiser), Megan Bergkessel (Participant), Thibault Rosazza (Participant), Henry McSorley (Participant), Kasper Rasmussen (Participant), Nur Kocaturk (Participant), Phoebe Crawley (Participant), Alexander Agrotis (Participant), Adrien Rousseau (Participant), Gopal Sapkota (Participant), Lorraine Glennie (Participant), Michael Hannan (Participant), Paul Appleton (Participant), Fabio Tamaki (Participant) & Ian Newton (Participant)
25 Jul 2022 → 29 Jul 2022
Activity: Other activity types › Schools engagement
Soapbox Science Dundee
Julieta Gómez García-Donas (Speaker), Giorgia De Paoli (Speaker), Sara Ten Have (Speaker), Nicola Morrice (Speaker), Andrea Rodriguez (Speaker), Anna Sanchez Avila (Speaker), Parul Dixit (Speaker), Catriona Aitken (Speaker), Stella Manoli (Speaker), Amy Cameron (Organiser), Heather Doran (Organiser), Amy Rogers (Organiser) & Lu Barnsby-Greer (Participant)
12 Mar 2022
Activity: Other activity types › Public engagement and outreach - festival/exhibition

A Forensic Approach to Street Drugs
Craig McKenzie & Kevin Read
23/01/19
1 Media contribution
Press/Media: Research
Tuberculosis drug may also target visceral leishmaniasis
Alan H. Fairlamb & Kevin Read
24/05/16
1 item of Media coverage
Press/Media: Research

Discovery of high quality molecular leads and screening collections for CNS drug targets
Author: Farnaby, W., 2019
Supervisor: Ciulli, A. (Supervisor) & Read, K. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Oocyst development in the parasite Cryptosporidium parvum
Author: Sands, E., 2023
Supervisor: Pawlowic, M. (Supervisor) & Gilbert, I. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
Spontaneous Raman spectroscopy: Exploring applicability in drug discovery and the medical sciences
Author: Rabl, T., 2018
Supervisor: Read, K. (Supervisor) & McGloin, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy