Gene Regulation and Expression

  • United Kingdom

Research Output 1992 2018

2018
1 Citations
Open Access
File
prealbumin
Prealbumin
Oxidopamine
Caenorhabditis elegans
Oxidative Stress

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Pao, K-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S. 11 Apr 2018 In : Nature. 556, p. 381-385 5 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Esterification
Ubiquitin
Genes
Ubiquitination
1 Citations

AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11

Piscitello, D., Varshney, D., Lilla, S., Vizioli, M. G., Reid, C., Gorbunova, V., Seluanov, A., Gillespie, D. A. & Adams, P. D. 25 Jan 2018 In : Oncogene. 37, p. 427-438 12 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Repair
Phosphotransferases
Down-Regulation
Oncogenes
DNA Damage

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K. 14 Jun 2018 In : Nature Communications. 9, 1, 2341

Research output: Contribution to journalArticle

Open Access
File
Natural Killer Cells
mice
amino acids
Lymphocytes
Glutamine

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

Liakath-Ali, K., Mills, E. W., Sequeira, I., Lichtenberger, B. M., Pisco, A. O., Sipilä, K. H., Mishra, A., Yoshikawa, H., Wu, C. C-C., Ly, T., Lamond, A. I., Adham, I. M., Green, R. & Watt, F. M. 11 Apr 2018 In : Nature. 556, p. 376-380 5 p.

Research output: Contribution to journalLetter

Ribosomes
Homeostasis
Stem Cells
Sirolimus
Quality Control

Biochemical and Structural Properties of Fungal Holliday Junction-Resolving Enzymes

Liu, Y., Freeman, A., Déclais, A-C., Gartner, A. & Lilley, D. M. J. 2018 Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination. Spies, M. & Malkova, A. (eds.). Academic Press, Vol. 600, p. 543-568 24 p. (Methods in Enzymology; vol. 600)

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Cruciform DNA
Structural properties
Enzymes
Chaetomium
DNA

Chromatin Replication and Histone Dynamics

Alabert, C., Jasencakova, Z. & Groth, A. 23 Jan 2018 DNA Replication : From Old Principles to New Discoveries. Masai, H. & Foiani, M. (eds.). Singapore, p. 311-333 23 p. (Advances in Experimental Medicine and Biology; vol. 1042)

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Histones
Chromatin
DNA Replication
Nucleosomes
Genomic Instability
1 Citations

Computational Modelling of Cancer Development and Growth: Modelling at Multiple Scales and Multiscale Modelling

Szymańska, Z., Cytowski, M., Mitchell, E., Macnamara, C. K. & Chaplain, M. May 2018 In : Bulletin of Mathematical Biology. 80, 5, p. 1366-1403 38 p.

Research output: Contribution to journalArticle

growth modeling
Multiscale Modeling
Multiple Scales
Computational Modeling
Growth and Development

E1B-55K mediated regulation of RNF4 STUbL promotes HAdV gene expression

Müncheberg, S., Hay, R. T., Ip, W. H., Meyer, T., Weiß, C., Brenke, J., Masser, S., Hadian, K., Dobner, T. & Schreiner, S. 25 Apr 2018 In : Journal of Virology.

Research output: Contribution to journalArticle

Open Access
File
Ligases
ubiquitin
Ubiquitin
ligases
Antiviral Agents

Effects of hypo O-GlcNAcylation on Drosophila development

Mariappa, D. N., Ferenbach, A. & van Aalten, D. M. F. 11 May 2018 In : Journal of Biological Chemistry. 293, 19, p. 7209-7221 13 p.

Research output: Contribution to journalArticle

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Drosophila
Genes
Phenotype
Mediator Complex

Inhibitors against Fungal Cell Wall Remodeling Enzymes

Delso, I., Valero-Gonzalez, J., Gomollón-Bel, F., Castro-López, J., Fang, W., Navratilova, I., van Aalten, D. M. F., Tejero, T., Merino, P. & Hurtado-Guerrero, R. 22 Jan 2018 In : ChemMedChem. 13, 2, p. 128-132 5 p.

Research output: Contribution to journalArticle

Triazoles
Aspergillus fumigatus
Glucans
X Ray Crystallography
Enzyme Inhibitors

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

Hong, Y., Sonneville, R., Wang, B., Scheidt, V., Meier, B., Woglar, A., Demetriou, S., Labib, K., Jantsch, V. & Gartner, A. 20 Feb 2018 In : Nature Communications. 9, p. 1-11 11 p., 728

Research output: Contribution to journalArticle

Open Access
File
Lunar Module
nuclease
mitosis
chromatin
Deoxyribonucleases

Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta

Almohammed, R., Osborn, K., Ramasubramanyan, S., Perez-Fernandez, I. B. N., Godfrey, A., Mancini, E. J. & Sinclair, A. J. 1 Jun 2018 In : Journal of General Virology. 99, p. 805-817 13 p.

Research output: Contribution to journalArticle

Open Access
File
Immune Evasion
Human Herpesvirus 4
Response Elements
Virus Latency
Genes

Morphological and genetic characterisation of the root system architecture of selected barley recombinant chromosome substitution lines using an integrated phenotyping approach

Canto, C. D. L. F., Kalogiros, D. I., Ptashnyk, M., George, T. S., Waugh, R., Bengough, A. G., Russell, J. & Dupuy, L. X. 14 Jun 2018 In : Journal of Theoretical Biology. 447, p. 84-97 14 p.

Research output: Contribution to journalArticle

Root Growth
substitution lines
Barley
Root System
Hordeum

mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II-dependent transcription

Varshney, D., Lombardi, O., Schweikert, G., Dunn, S., Suska, O. & Cowling, V. May 2018 In : Cell Reports. 23, 5, p. 1530-1542 13 p.

Research output: Contribution to journalArticle

Open Access
File
RNA Polymerase II
Methyltransferases
Random access storage
Transcription
Messenger RNA

Mutational signatures of DNA mismatch repair deficiency in and human cancers

Meier, B., Volkova, N. V., Hong, Y., Schofield, P., Campbell, P. J., Gerstung, M. & Gartner, A. May 2018 In : Genome Research. 28, 5, p. 666-675 10 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Repair-Deficiency Disorders
DNA Mismatch Repair
Neoplasms
Genome
Cytosine
1 Citations
Open Access
File
Oxidopamine
apoptosis
Caenorhabditis elegans
mutation
Dopaminergic Neurons

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry

Borodkin, V. S., Rafie, K., Selvan, N., Aristotelous, T., Navratilova, I., Ferenbach, A. T. & Van Aalten, D. M. F. 18 May 2018 In : ACS Chemical Biology. 13, 5, p. 1353-1360 8 p.

Research output: Contribution to journalArticle

Polarimeters
Fluorescence
Assays
Hexosaminidase B
Cardiovascular Diseases

PAWS1controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP

Cummins, T. D., Wu, K. Z. L., Bozatzi, P., Dingwell, K. S., Macartney, T. J., Wood, N. T., Varghese, J., Gourlay, R., Campbell, D. G., Prescott, A., Griffis, E., Smith, J. C. & Sapkota, G. P. 10 Jan 2018 In : Journal of Cell Science. 131, 1, p. 1-12 12 p., jcs202390

Research output: Contribution to journalArticle

Open Access
File
Cell Movement
Actins
Clustered Regularly Interspaced Short Palindromic Repeats
Focal Adhesions
Osteosarcoma

Positioning Europe for the EPITRANSCRIPTOMICS challenge

Jantsch, M. , Quattrone, A. , O'Connell, M. , Helm, M. , Frye, M. , Macias-Gonzales, M. , Ohman, M. , Ameres, S. , Willems, L. , Fuks, F. , Oulas, A. , Vanacova, S. , Nielsen, H. , Bousquet-Antonelli, C. , Motorin, Y. , Roignant, J-Y. , Balatsos, N. , Dinnyes, A. , Baranov, P. , Kelly, V. & 40 others Lamm, A., Rechavi, G., Pelizzola, M., Liepins, J., Holodnuka Kholodnyuk, I., Zammit, V., Ayers, D., Drablos, F., Dahl, J. A., Bujnicki, J., Jeronimo, C., Almeida, R., Neagu, M., Costache, M., Bankovic, J., Banovic, B., Kyselovic, J., Valor, L. M., Selbert, S., Pir, P., Demircan, T., Cowling, V., Schäfer, M., Rossmanith, W., Lafontaine, D., David, A., Carre, C., Lyko, F., Schaffrath, R., Schwartz, S., Verdel, A., Klungland, A., Purta, E., Timotijevic, G., Cardona, F., Davalos, A., Ballana, E., O Carroll, D., Ule, J. & Fray, R. 9 May 2018 In : RNA Biology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Epigenomics
DNA
RNA
Research
Regeneration
File
Proteome
Breast
Epithelial Cells
Proteins
Oncogenes

Proteomic analysis of the cell cycle of procylic form Trypanosoma brucei

Crozier, T. W. M., Tinti, M., Wheeler, R. J., Ly, T., Ferguson, M. A. J. & Lamond, A. I. 1 Jun 2018 In : Molecular & Cellular Proteomics. 17, p. 1184-1195 12 p.

Research output: Contribution to journalArticle

Open Access
File
Trypanosoma brucei brucei
Proteomics
Trypanosomiasis
Cell Cycle
Cells

Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila

Clemente, G. D., Hannaford, M. R., Beati, H., Kapp, K., Januschke, J., Griffis, E. R. & Müller, H-A. J. 30 Mar 2018 In : Journal of Developmental Biology. 6, 2, 23 p., 9

Research output: Contribution to journalArticle

Open Access
File
Dyneins
Drosophila
Kinetochores
Germ Cells
Prometaphase

RNF12 X-linked intellectual disability mutations disrupt E3 ligase activity and neural differentiation

Bustos, F., Segarra Fas, A., Chaugule, V. K., Brandenburg, L., Branigan, E., Toth, R., Macartney, T., Knebel, A., Hay, R., Walden, H. & Findlay, G. 8 May 2018 In : Cell Reports. 23, p. 1599-1611 14 p.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitin-Protein Ligases
Stem cells
Intellectual Disability
Mutation
Genes

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron

Gray, K. M., Kaifer, K. A., Baillat, D., Wen, Y., Bonacci, T. R., Ebert, A. D., Raimer, A. C., Spring, A. M., Have, S. T., Glascock, J. J., Gupta, K., Van Duyne, G. D., Emanuele, M. J., Lamond, A. I., Wagner, E. J., Lorson, C. L. & Matera, A. G. 15 Jan 2018 In : Molecular Biology of the Cell. 29, 2, p. 96-110 15 p.

Research output: Contribution to journalArticle

Open Access
File
Motor Neurons
Protein Isoforms
Spinal Muscular Atrophy
Exons
Duplicate Genes

SINHCAF/FAM60A and SIN3A specifically repress HIF 2α expression

Biddlestone, J., Batie, M., Bandarra, D., Munoz, I. & Rocha, S. 21 May 2018 In : Biochemical Journal.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Transcription Factors
Messenger RNA
Proteins
Hypoxia

Spindly is required for rapid migration of human cells

Conte, C., Baird, M. A., Davidson, M. W. & Griffis, E. R. 23 Apr 2018 In : Open Biology. 033233

Research output: Contribution to journalArticle

Open Access
File
Dyneins
Cell Movement
Cells
Microtubules
Kinetochores

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

Hepburn, L., McHugh, A., Fernandes, K., Boag, . G., Proby, C., Leigh, I. & Saville, M. 1 May 2018 In : Oncotarget. 9, 33, p. 23029-23046 18 p.

Research output: Contribution to journalArticle

Open Access
File
Spliceosomes
Cell- and Tissue-Based Therapy
Squamous Cell Carcinoma
Skin
Neoplasms
1 Citations

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K. 2 Mar 2018 In : ChemBioChem. 19, 5, p. 425-429 5 p.

Research output: Contribution to journalArticle

Open Access
File
Niclosamide
Anthelmintics
Protein Kinases
Parkinson Disease
Mitochondrial Membrane Potential

The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans

Hong, Y., Velkova, M., Silva, N., Jagut, M., Scheidt, V., Labib, K., Jantsch, V. & Gartner, A. 7 Jun 2018 In : PLoS Genetics. 14, 6, p. 1-22 22 p., e1007453

Research output: Contribution to journalArticle

Open Access
3'-nucleotidase
Recombinational DNA Repair
Chromosome Segregation
chromosome segregation
nucleases
1 Citations

The Encyclopedia of Proteome Dynamics – A big data ecosystem for (prote)omics

Brenes Murillo, A., Afzal, V., Kent, R. & Lamond, A. 4 Jan 2018 In : Nucleic Acids Research. 46, D1, p. D1202-D1209 8 p.

Research output: Contribution to journalArticle

Open Access
File
Encyclopedias
Proteome
Proteomics
Ecosystem
Genomics

The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix

Gundogdu, M., Llabres, S., Gorelik, A., Ferenbach, A., Zachariae, U. & Van Aalten, D. 21 Jun 2018 In : Cell Chemical Biology. 25, p. 1-6 1 p.

Research output: Contribution to journalArticle

Open Access
File
Intellectual Disability
Mutation
Acetylglucosamine
Post Translational Protein Processing
Brain

Thio-linked UDP-peptide conjugates as O-GlcNAc transferase inhibitors

Rafie, K., Gorelik, A., Trapannone, R., Borodkin, V. & Van Aalten, D. 3 May 2018 In : Bioconjugate Chemistry. p. 3/5/18

Research output: Contribution to journalArticle

Open Access
Uridine Diphosphate
Peptides
Polarimeters
Fluorophores
Cell-Penetrating Peptides

UDP-GlcNAc Analogues as Inhibitors of O-GlcNAc Transferase (OGT): Spectroscopic, Computational, and Biological Studies

Ghirardello, M., Perrone, D., Chinaglia, N., Sádaba, D., Delso, I., Tejero, T., Marchesi, E., Fogagnolo, M., Rafie, K., van Aalten, D. M. F. & Merino, P. 30 Apr 2018 In : Chemistry: a European Journal. 24, 28, p. 7264-7272 9 p.

Research output: Contribution to journalArticle

Uridine Diphosphate
Phosphates
Saturation (materials composition)
Sugars
Nuclear magnetic resonance spectroscopy

Visualization of Biomedical Data

O'Donoghue, S. I., Baldi, B. F., Clark, S. J., Darling, A. E., Hogan, J. M., Kaur, S., Maier-Hein, L., McCarthy, D. J., Moore, W., Stenau, E., Swedlow, J., Vuong, J. & Procter, J. 14 May 2018 In : Annual Review of Biomedical Data Science. 1

Research output: Contribution to journalArticle

Open Access
Learning
Metagenomics
Foster Home Care
Genomics
Research
2017

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

Makrantoni, V., Ciesiolka, A., Lawless, C., Fernius, J., Marston, A. L., Lydall, D. & Stark, M. J. R. 7 Sep 2017 In : G3 : Genes, Genomes, Genetics. 7, 9, p. 3203-3215 13 p.

Research output: Contribution to journalArticle

Open Access
File
Kinetochores
Gene Knockout Techniques
Saccharomyces cerevisiae
Nonsense Mediated mRNA Decay
Large Ribosome Subunits
8 Citations

A high quality Arabidopsis transcriptome for accurate transcript-level analysis of alternative splicing

Zhang, R., Calixto, C. P. G., Marquez, Y., Venhuizen, P., Tzioutziou, N. A., Guo, W., Spensley, M., Entizne, J. C., Lewandowska, D., ten Have, S., Frei dit Frey, N., Hirt, H., James, A. B., Nimmo, H. G., Barta, A., Kalyna, M. & Brown, J. W. S. 19 May 2017 In : Nucleic Acids Research. 45, 9, p. 5061-5073 13 p.

Research output: Contribution to journalArticle

Open Access
File
Alternative Splicing
Transcriptome
Arabidopsis
Protein Isoforms
RNA
1 Citations

ALADIN is Required for the Production of Fertile Mouse Oocytes

Carvalhal, S., Stevense, M., Koehler, K., Naumann, R., Huebner, A., Jessberger, R. & Griffis, E. R. 17 Sep 2017 In : Molecular Biology of the Cell. 28, 19, p. 2470-2478 9 p.

Research output: Contribution to journalArticle

Open Access
File
Oocytes
Polar Bodies
Anaphase
Spindle Apparatus
Asymmetric Cell Division
7 Citations

A mutant O-GlcNAcase enriches Drosophila developmental regulators

Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F. Aug 2017 In : Nature Chemical Biology. 13, 8, p. 882-887 8 p.

Research output: Contribution to journalArticle

Open Access
File
Drosophila
Embryonic Development
Proteins
Comb and Wattles
Homeobox Genes
1 Citations

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

Mishra, A., Oulès, B., Pisco, A. O., Ly, T., Liakath-Ali, K., Walko, G., Viswanathan, P., Tihy, M., Nijjhar, J., Dunn, S-J., Lamond, A. I. & Watt, F. M. 18 Oct 2017 In : eLife. 6, p. 1-20 20 p., e27356

Research output: Contribution to journalArticle

Open Access
File
Phosphoprotein Phosphatases
Phosphoric Monoester Hydrolases
Epidermis
Homeostasis
Commitment of Mentally Ill
6 Citations

A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

Tatham, M. H., Cole, C., Scullion, P., Wilkie, R., Westwood, N. J., Stark, L. A. & Hay, R. T. 1 Feb 2017 In : Molecular & Cellular Proteomics. 16, 2, p. 310-326 17 p.

Research output: Contribution to journalArticle

Open Access
File
Acetylation
Proteomics
Aspirin
Lysine
acetylsalicylic acid lysinate
2 Citations

A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans

González-Huici, V., Wang, B. & Gartner, A. 1 Aug 2017 In : Genetics. 206, 4, p. 1853-1864 12 p.

Research output: Contribution to journalArticle

Open Access
File
Nonsense Mediated mRNA Decay
Genomic Instability
Caenorhabditis elegans
Ionizing Radiation
DNA Damage
7 Citations

A SUMO-Dependent Protein Network Regulates Chromosome Congression During Oocyte Meiosis

Pelisch, F., Tammsalu, T., Wang, B., Jaffray, E. G., Gartner, A. & Hay, R. T. 5 Jan 2017 In : Molecular Cell. 65, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

Open Access
File
SUMO-1 Protein
Meiosis
Oocytes
Small Ubiquitin-Related Modifier Proteins
Chromosomes
3 Citations

Autophagosomes cooperate in the degradation of intracellular C-terminal fragments of the amyloid precursor protein via the MVB/lysosomal pathway

González, A. E., Muñoz, V. C., Cavieres, V. A., Bustamante, H. A., Cornejo, V-H., Januário, Y. C., González, I., Hetz, C., daSilva, L. L., Rojas-Fernández, A., Hay, R. T., Mardones, G. A. & Burgos, P. V. Jun 2017 In : FASEB Journal. 31, 6, p. 2446-2459 14 p.

Research output: Contribution to journalArticle

Open Access
File
Amyloid beta-Protein Precursor
Degradation
Lysosomal-Associated Membrane Protein 1
Autophagy
Organelles
2 Citations
Open Access
File
Regulator Genes
Protein Isoforms
Genes
Specifications
Pluripotent Stem Cells
Open Access
File
M Phase Cell Cycle Checkpoints
Genomic Instability
Caenorhabditis elegans
Ionizing Radiation
DNA Damage
1 Citations

Cell cycle RNA regulons coordinating early lymphocyte development

Galloway, A. & Turner, M. 2017 In : Wiley Interdisciplinary Reviews: RNA. 8, 5, p. 1-15 15 p., e1419

Research output: Contribution to journalArticle

Open Access
File
Regulon
Lymphocytes
Cell Cycle
RNA-Binding Proteins
Cells

Characterisation of the biflavonoid hinokiflavone as a premRNA splicing modulator that inhibits SENP

Pawellek, A., Ryder, U., Tammsalu, T., King, L. J., Kreinin, H., Ly, T., Hartley, R. & Lamond, A. 8 Sep 2017 In : eLife. 6, e27402

Research output: Contribution to journalArticle

Open Access
File
Biflavonoids
Modulators
Sumoylation
Cells
Cell Line

c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

Dunn, S., Lombardi, O. & Cowling, V. 20 Jan 2017 In : Biochemical Journal. 474, 3, p. 377-384 8 p.

Research output: Contribution to journalArticle

Open Access
File
Methylation
Random access storage
Ribosomal RNA
Messenger RNA
Cell Nucleus Active Transport
29 Citations

Common genetic variation drives molecular heterogeneity in human iPSCs

Kilpinen, H. , Goncalves, A. , Leha, A. , Afzal, V. , Alasoo, K. , Ashford, S. , Bala, S. , Bensaddek, D. , Casale, F. P. , Culley, O. J. , Danecek, P. , Faulconbridge, A. , Harrison, P. W. , Kathuria, A. , McCarthy, D. J. , McCarthy, S. A. , Meleckyte, R. , Memari, Y. , Moens, N. , Soares, F. & 23 others Mann, A., Streeter, I., Agu, C. A., Alderton, A., Nelson, R., Harper, S., Patel, M., White, A., Patel, S. R., Clarke, L., Halai, R., Kirton, C. M., Kolb-Kokocinski, A., Beales, P. L., Birney, E., Danovi, D., Lamond, A. I., Ouwehand, W. H., Vallier, L., Watt, F. M., Durbin, R., Stegle, O. & Gaffney, D. J. 15 Jun 2017 In : Nature. 546, 7658, p. 370-375 6 p.

Research output: Contribution to journalArticle

Open Access
File
Induced Pluripotent Stem Cells
Cell Line
Transcriptome
Individuality
Drive