Gene Regulation and Expression

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1994

Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract

Cardinali, B., Cohen, P. T. W. & Lamond, A. I., 3 Oct 1994, In : FEBS Letters. 352, 3, p. 276-280 5 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits

Comai, L. ., Zomerdijk, J. C., Beckmann, H., Zhou, S., Admon, A. & Tjian, R., 1994, In : Science. 266, 5193, p. 1966-1972 7 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism

Mermoud, J. E., Cohen, P. T. W. & Lamond, A. I., 1 Dec 1994, In : EMBO Journal. 13, 23, p. 5679-5688 10 p.

Research output: Contribution to journalArticle

255 Citations (Scopus)

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

Weis, K., Rambaud, S., Lavau, C., Jansen, J., Carvalho, T., Carmo-Fonseca, M., Lamond, A. & Dejean, A., 28 Jan 1994, In : Cell. 76, 2, p. 345-356 12 p.

Research output: Contribution to journalArticle

598 Citations (Scopus)
76 Citations (Scopus)

The linear-plasmid-encoded toxin produced by the yeast Pichia acaciae : characterization and comparison with the toxin of Kluyveromyces lactis

McCracken, D. A., Martin, V. J., Stark, M. J. R. & Bolen, P. L., Feb 1994, In : Microbiology. 140, p. 425-431 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Two Saccharomyces cerevisiae genes which control sensitivity to G1 arrest induced by Kluyveromyces lactis toxin

BUTLER, ANDREW. R., WHITE, JOHN. H., FOLAWIYO, YETUNDE., EDLIN, ANGELA., GARDINER, DONALD. & STARK, MICHAEL. J. R., Sep 1994, In : Molecular and Cellular Biology. 14, 9, p. 6306-6316 11 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)
1995

A regulated MET3-GLC7 gene fusion provides evidence of a mitotic role for Saccharomyces cerevisiae protein phosphatase 1.

Black, S., Andrews, P. D., Sneddon, A. A. & Stark, M. J. R., 30 Jun 1995, In : Yeast. 11, 8, p. 747-759 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Dynamic organization of splicing factors in adenovirus-infected cells

Bridge, E., Xia, D. X., Carmo-Fonseca, M., Cardinali, B., Lamond, A. I. & Pettersson, U., 1 Jan 1995, In : Journal of Virology. 69, 1, p. 281-290 10 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Identification of hnRNP P2 as TLS/FUS using electrospray mass spectrometry

Calvio, C., Neubauer, G., Mann, M. & Lamond, A. I., Sep 1995, In : RNA. 1, 7, p. 724-733 10 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Identification of hSRP1α as a functional receptor for nuclear localization sequences

Weis, K., Mattaj, I. W. & Lamond, A. I., 19 May 1995, In : Science. 268, 5213, p. 1049-1053 5 p.

Research output: Contribution to journalArticle

300 Citations (Scopus)

Influenza virus NS1 protein alters the subnuclear localization of cellular splicing components

Fortes, P., Lamond, A. I. & Ortin, J., 1 Apr 1995, In : Journal of General Virology. 76, 4, p. 1001-1007 7 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Molecular analysis of the coiled body

Bohmann, K., Ferreira, J., Santama, N., Weis, K. & Lamond, A. I., 1 Jan 1995, In : Journal of Cell Science. 108, SUPPL. 19, p. 107-113 7 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus

Bohmann, K., Ferreira, J. A. & Lamond, A. I., 15 Nov 1995, In : Journal of Cell Biology. 131, 4, p. 817-831 15 p.

Research output: Contribution to journalArticle

Open Access
136 Citations (Scopus)

RNA Processing: Wilms' tumour - the splicing connection?

Lamond, A. I., Aug 1995, In : Current Biology. 5, 8, p. 862-865 4 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase

MACKELVIE, SARAH. H., ANDREWS, PAUL. D. & STARK, MICHAEL. J. R., Jul 1995, In : Molecular and Cellular Biology. 15, 7, p. 3777-3785 9 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)
1996

Analysis of intra-specific somatic hybrids of potato (Solanum tuberosum) using simple sequence repeats

Provan, J., Kumar, A., Shepherd, L., Powell, W. & Waugh, R., Dec 1996, In : Plant Cell Reports. 16, 3-4, p. 196-199 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

Weis, K., Dingwall, C. & Lamond, A. I., 16 Dec 1996, In : EMBO Journal. 15, 24, p. 7120-7128 9 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

Cis-acting elements distinct from the 5' splice site promote U1- independent pre-mRNA splicing

Crispino, J. D., Mermoud, J. E., Lamond, A. I. & Sharp, P. A., 19 Nov 1996, In : RNA. 2, 7, p. 664-673 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Mutations which block the binding of calmodulin to Spc110p cause multiple mitotic defects

Stirling, D. A., Rayner, T. F., Prescott, A. R. & Stark, M. J. R., 1996, In : Journal of Cell Science. 109, p. 1297-1310 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

RNA splicing: Unexpected spliceosome diversity

Kreivi, J. P. & Lamond, A. I., 1 Jan 1996, In : Current Biology. 6, 7, p. 802-805 4 p.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)

The conserved amino-terminal domain of hSRP1α is essential for nuclear protein import

Weis, K., Ryder, U. & Lamond, A. I., 15 Apr 1996, In : EMBO Journal. 15, 8, p. 1818-1825 8 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)

The dynamics of coiled bodies in the nucleus of adenovirus-infected cells

Rebelo, L., Almeida, F., Ramos, C., Bohmann, K., Lamond, A. I. & Carmo-Fonseca, M., 1 Jul 1996, In : Molecular Biology of the Cell. 7, 7, p. 1137-1151 15 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
16 Citations (Scopus)
1997
50 Citations (Scopus)

Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus

Lyon, C. E., Bohmann, K., Sleeman, J. & Lamond, A. I., 10 Jan 1997, In : Experimental Cell Research. 230, 1, p. 84-93 10 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Spatial organization of large-scale chromatin domains in the nucleus: A magnified view of single chromosome territories

Ferreira, J., Paolella, G., Ramos, C. & Lamond, A. I., 29 Dec 1997, In : Journal of Cell Biology. 139, 7, p. 1597-1610 14 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)
1998

Cloning and characterization of hSRP1γ, a tissue-specific nuclear transport factor

Nachury, M. V., Ryder, U. W., Lamond, A. I. & Weis, K., 20 Jan 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 2, p. 582-587 6 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein

Sleeman, J., Lyon, C. E., Platani, M., Kreivi, J. P. & Lamond, A. I., 15 Sep 1998, In : Experimental Cell Research. 243, 2, p. 290-304 15 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Identification and characterization of the KlCMD1 gene encoding Kluyveromyces lactis calmodulin

Rayner, T. F. & Stark, M. J. R., 1998, In : Yeast. 14, 9, p. 869-875 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins

Zachariae, W., Shevchenko, A., Andrews, P. D., Ciosk, R., Galova, M., Stark, M. J. R., Mann, M. & Nasmyth, K., 1998, In : Science. 279, 5354, p. 1216-1219 4 p.

Research output: Contribution to journalArticle

283 Citations (Scopus)

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

Neubauer, G., King, A., Rappsilber, J., Calvio, C., Watson, M., Ajuh, P., Sleeman, J., Lamond, A. & Mann, M., Sep 1998, In : Nature Genetics. 20, 1, p. 46-50 5 p.

Research output: Contribution to journalArticle

401 Citations (Scopus)

Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase

Thomson, A. M., Meyer, D. J. & Hayes, J. D., 15 Jul 1998, In : Biochemical Journal. 333 ( Pt 2), p. 317-25 9 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei

Chaves, I., Zomerdijk, J., Dirks-Mulder, A., Dirks, R. W., Raap, A. K. & Borst, P., 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 21, p. 12328-12333 6 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

Davies, R. C., Calvio, C., Bratt, E., Larsson, S. H., Lamond, A. I. & Hastie, N. D., 15 Oct 1998, In : Genes and Development. 12, 20, p. 3217-3225 9 p.

Research output: Contribution to journalArticle

193 Citations (Scopus)
1999

An extreme cytoplasmic bottleneck in the modern European cultivated potato (Solanum tuberosum) is not reflected in decreased levels of nuclear diversity

Provan, J., Powell, W., Dewar, H., Bryan, G., Machray, G. C. & Waugh, R., 22 Mar 1999, In : Proceedings of the Royal Society B: Biological Sciences. 266, 1419, p. 633-639 7 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins

Rowles, A., Tada, S. & Blow, J. J., 1999, In : Journal of Cell Science. 112 , 12, p. 2011-2018 8 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Control of the terminal step of intracellular membrane fusion by protein phosphatase 1

Peters, C., Andrews, P. D., Stark, M. J. R., Cesaro-Tadic, S., Glatz, A., Podtelejnikov, A., Mann, M. & Mayer, A., 1999, In : Science. 285, 5430, p. 1084-1087 4 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Purification and depletion of RNP particles by antisense affinity chromatography.

Blencowe, B. J. & Lamond, A. I., 1999, In : Methods in Molecular Biology (Clifton, N.J.). 118, p. 275-287 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p

Sassoon, I., Severin, F. F., Andrews, P. D., Taba, M-R., Kaplan, K. B., Ashford, A. J., Stark, M. J. R., Sorger, P. K. & Hyman, A. A., 1999, In : Genes & Development. 13, 5, p. 545-555 11 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)

Saying a firm 'no' to DNA re-replication

Blow, J. J. & Prokhorova, T. A., 1999, In : Nature Cell Biology. 1, 7, p. E175-E177 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The regulation of replication origin activation

Donaldson, A. D. & Blow, J. J., 1999, In : Current Opinion in Genetics & Development. 9, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

The RLF-B component of the replication licensing system is distinct from Cdc6 and functions after Cdc6 binds to chromatin

Tada, S., Chong, J. P. J., Mahbubani, H. M. & Blow, J. J., 1999, In : Current Biology. 9, 4, p. 211-214 4 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2000

A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans

Gartner, A., Milstein, S., Ahmed, S., Hodgkin, J. & Hengartner, M. O., 2000, In : Molecular Cell. 5, 3, p. 435-443 9 p.

Research output: Contribution to journalArticle

368 Citations (Scopus)

A novel 'two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans

Appleyard, M. V. C. L., McPheat, W. L. & Stark, M. J. R., 2000, In : Current Genetics. 37, 6, p. 364-372 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

A recQ family DNA helicase gene from Aspergillus nidulans

Appleyard, M. V. C. L., McPheat, W. L. & Stark, M. J. R., 2000, In : Mitochondrial DNA. 11, 3-4, p. 315-319 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cell cycle: a new check on issuing the licence

Blow, J. J. & Tada, S., 2000, In : Nature. 404, 6778, p. 560-561 2 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth

Andrews, P. D. & Stark, M. J. R., 2000, In : Journal of Cell Science. 113, 15, p. 2685-2693 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)