Gene Regulation and Expression

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2002

Cell type-specific responses of human cells to inhibition of replication licensing

Shreeram, S., Sparks, A., Lane, D. P. & Blow, J. J., 2002, In : Oncogene. 21, 43, p. 6624-6632 9 p.

Research output: Contribution to journalArticle

139 Citations (Scopus)

Directed proteomic analysis of the human nucleolus

Andersen, J. S., Lyon, C. E., Fox, A. H., Leung, A. K. L., Lam, Y. W., Steen, H., Mann, M. & Lamond, A. I., Jan 2002, In : Current Biology. 12, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

756 Citations (Scopus)

Essential functions of Sds22p in chromosome stability and nuclear localization of PP1

Peggie, M., MacKelvie, S., Bloecher, A., Knatko, E., Tatchell, K. & Stark, M., 2002, In : Journal of Cell Science. 115, 1, p. 195-206 12 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

Tanaka, T. U., Rachidi, N., Janke, C., Pereira, G., Galova, M., Schiebel, E., Stark, M. J. R. & Nasmyth, K., 2002, In : Cell. 108, 3, p. 317-329 13 p.

Research output: Contribution to journalArticle

527 Citations (Scopus)

Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

Kimber, W. A., Trinkle-Mulcahy, L., Cheung, P. C. F., Deak, M., Marsden, L. J., Kieloch, A., Watt, S., Javier, R. T., Gray, A., Downes, C. P., Lucocq, J. M. & Alessi, D. R., 1 Feb 2002, In : Biochemical Journal. 361, 3, p. 525-536 12 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation

Janke, C., Ortíz, J., Tanaka, T. U., Lechner, J. & Schiebel, E., 2002, In : EMBO Journal. 21, 1-2, p. 181-93 13 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import

Hodgson, B., Li, A., Tada, S. & Blow, J. J., 2002, In : Current Biology. 12, 8, p. 678-683 6 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Inhibition of autophagy in mitotic animal cells

Eskelinen, E-L., Prescott, A. R., Cooper, J., Brachmann, S. M., Wang, L., Tang, X., Backer, J. M. & Lucocq, J. M., 2002, In : Traffic. 3, 12, p. 878-893 16 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)
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43 Citations (Scopus)
676 Downloads (Pure)

Large-scale isolation of Cajal bodies from HeLa cells

Lam, Y. W., Lyon, C. E. & Lamond, A. I., Jul 2002, In : Molecular Biology of the Cell. 13, 7, p. 2461-2473 13 p.

Research output: Contribution to journalArticle

Open Access
64 Citations (Scopus)

Mammalian nuclei become licensed for DNA replication during late telophase

Dimitrova, D. S., Prokhorova, T. A., Blow, J. J., Todorov, I. T. & Gilbert, D. M., 2002, In : Journal of Cell Science. 115, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)
15 Citations (Scopus)

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, J. R., Hu, K., Andrews, P. D., Roos, D. S. & Murray, J. M., 19 Feb 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2014-2019 6 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-Kinase in 1321N1 astrocytoma cells

Tang, X., Batty, I. H. & Downes, C. P., Jan 2002, In : Journal of Biological Chemistry. 277, 1, p. 338-344 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry

Walsh, E. P., Lamont, D. J., Beattie, K. A. & Stark, M. J. R., 2002, In : Biochemistry. 41, 7, p. 2409-2420 12 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Nuclear processes controlled by molecular machines

Fox, A. H. & Lamond, A. I., 23 May 2002, In : Genome Biology. 3, 6, p. 4016.1-4016.3 3 p., 4016.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nup98 is a mobile nucleoporin with transcription-dependent dynamics

Griffis, E. R., Altan, N., Lippincott-Schwartz, J. & Powers, M. A., 2002, In : Molecular Biology of the Cell. 13, 4, p. 1282-97 16 p.

Research output: Contribution to journalArticle

184 Citations (Scopus)

P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2

Xirodimas, D. P., Chisholm, J., Desterro, J. M. S., Lane, D. P., Hay, R. T. & Celis, J. (ed.), 2002, In : FEBS Letters. 528, 1-3, p. 207-211 5 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Paraspeckles: a novel nuclear domain

Fox, A. H., Lam, Y. W., Leung, A. K. L., Lyon, C. E., Andersen, J., Mann, M. & Lamond, A. I., Jan 2002, In : Current Biology. 12, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

317 Citations (Scopus)

Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity

Fichtner, L., Frohloff, F., Jablonowski, D., Stark, M. J. R. & Schaffrath, R., Aug 2002, In : Molecular Microbiology. 45, 3, p. 817-26 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Replication licensing - origin licensing: defining the proliferative state?

Blow, J. J. & Hodgson, B., 2002, In : Trends in Cell Biology. 12, 2, p. 72-78 7 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)

Splicing regulation at the second catalytic step by Sex-lethal involves 3′ splice site recognition by SPF45

Lallena, M. J., Chalmers, K. J., Llamazares, S., Lamond, A. I. & Valcárcel, J., 3 May 2002, In : Cell. 109, 3, p. 285-296 12 p.

Research output: Contribution to journalArticle

Open Access
109 Citations (Scopus)

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells

Moore, W. J., Zhang, C. & Clarke, P. R., Aug 2002, In : Current Biology. 12, 16, p. 1442-1447 6 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98

Hodel, A. E., Hodel, M. R., Griffis, E. R., Hennig, K. A., Ratner, G. A., Xu, S. & Powers, M. A., 2002, In : Molecular Cell. 10, 2, p. 347-58 12 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Yeast Pescadillo is required for multiple activities during 60s ribosomal subunit synthesis

Oeffinger, M., Lueng, A., Lamond, A. & Tollervey, D., 21 May 2002, In : RNA. 8, 5, p. 626-636 11 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2003

An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export

Kendirgi, F., Barry, D. M., Griffis, E. R., Powers, M. A. & Wente, S. R., 2003, In : Journal of Cell Biology. 160, 7, p. 1029-40 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

A new role for Ran in ensuring precise duplication of chromosomal DNA

Blow, J. J., 2003, In : Cell. 113, 1, p. 2-4 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Asymmetry in the assembly of the RNAi enzyme complex

Schwarz, D. S., Hutvagner, G., Du, T., Xu, Z., Aronin, N. & Zamore, P. D., 2003, In : Cell. 115, 2, p. 199-208 10 p.

Research output: Contribution to journalArticle

2024 Citations (Scopus)

Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase

Jowsey, I. R., Thomson, R. E., Orton, T. C., Elcombe, C. R. & Hayes, J. D., 2003, In : Biochemical Journal. 373, Pt 2, p. 559-69 11 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo

Sleeman, J. E., Trinkle-Mulcahy, L., Prescott, A. R., Ogg, S. C. & Lamond, A. I., 1 Apr 2003, In : Journal of Cell Science. 116, 10, p. 2039-2050 12 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Collection and characterisation of bacterial membrane proteins

Saidijam, M., Psakis, G., Clough, J. L., Meuller, J., Suzuki, S., Hoyle, C. J., Palmer, S. L., Morrison, S. M., Pos, M. K., Essenberg, R. C., Maiden, M. C. J., Abu-bakr, A., Baumberg, S. G., Neyfakh, A. A., Griffith, J. K., Stark, M. J., Ward, A., O'Reilly, J., Rutherford, N. G., Phillips-Jones, M. K. & 4 others, Henderson, P. J. F., von Heijne, G. (ed.), Rydstrom, J. (ed.) & Brzezinski, P. (ed.), 27 Nov 2003, In : FEBS Letters. 555, 1, p. 170-5 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Degradation ensures integrity

Li, A. & Blow, J. J., 2003, In : Nature. 423, 6942, p. 818-9 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dynamic properties of nucleosomes during thermal and ATP-driven mobilization

Flaus, A. & Owen-Hughes, T., 2003, In : Molecular and Cellular Biology. 23, 21, p. 7767-7779 13 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex

Sutherland, C. M., Hawley, S. A., McCartney, R. R., Leech, A., Stark, M. J. R., Schmidt, M. C. & Hardie, D. G., 5 Aug 2003, In : Current Biology. 13, 15, p. 1299-1305 7 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)

Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification

Fichtner, L., Jablonowski, D., Schierhorn, A., Kitamoto, H. K., Stark, M. J. R. & Schaffrath, R., Sep 2003, In : Molecular Microbiology. 49, 5, p. 1297-307 11 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
51 Citations (Scopus)
27 Citations (Scopus)

Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities

Bruno, M., Flaus, A., Stockdale, C., Rencurel, C., Ferreira, H. & Owen-Hughes, T., 2003, In : Molecular Cell. 12, 6, p. 1599-1606 8 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)

hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing

Leonard, D., Ajuh, P. M., Lamond, A. I. & Legerski, R. J., 5 Sep 2003, In : Biochemical and Biophysical Research Communications. 308, 4, p. 793-801 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1

Ajuh, P. & Lamond, A. I., 1 Nov 2003, In : Nucleic Acids Research. 31, 21, p. 6104-6116 13 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Informatics and quantitative analysis in biological imaging

Swedlow, J. R., Goldberg, I., Brauner, E. & Sorger, P. K., Apr 2003, In : Science. 300, 5616, p. 100-102 3 p.

Research output: Contribution to journalArticle

182 Citations (Scopus)

Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I

Rabitsch, K. P., Petronczki, M., Javerzat, J-P., Genier, S., Chwalla, B., Schleiffer, A., Tanaka, T. U. & Nasmyth, K., 2003, In : Developmental Cell. 4, 4, p. 535-48 14 p.

Research output: Contribution to journalArticle

156 Citations (Scopus)

Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes

Griffis, E. R., Xu, S. & Powers, M. A., 2003, In : Molecular Biology of the Cell. 14, 2, p. 600-10 11 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

P300 transcriptional repression is mediated by SUMO modification

Girdwood, D., Bumpass, D., Vaughan, O. A., Thain, A., Anderson, L. A., Snowden, A. W., Garcia-Wilson, E., Perkins, N. D. & Hay, R. T., Apr 2003, In : Molecular Cell. 11, 4, p. 1043-1054 12 p.

Research output: Contribution to journalArticle

360 Citations (Scopus)

p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor

Rocha, S., Campbell, K. J. & Perkins, N. D., Jul 2003, In : Molecular Cell. 12, 1, p. 15-25 11 p.

Research output: Contribution to journalArticle

169 Citations (Scopus)

p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1

Rocha, S., Martin, A. M., Meek, D. W. & Perkins, N. D., Jul 2003, In : Molecular and Cellular Biology. 23, 13, p. 4713-4727 15 p.

Research output: Contribution to journalArticle

180 Citations (Scopus)

Prostaglandin D2 synthase enzymes and PPARγ are co-expressed in mouse 3T3-L1 adipocytes and human tissues

Jowsey, I. R., Murdock, P. R., Moore, G. B. T., Murphy, G. J., Smith, S. A. & Hayes, J. D., 2003, In : Prostaglandins & Other Lipid Mediators. 70, 3-4, p. 267-84 18 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Protein phosphatase 4 interacts with the survival of motor neurons complex and enhances the temporal localisation of snRNPs

Carnegie, G. K., Sleeman, J. E., Morrice, N., Hastie, C. J., Peggie, M. W., Philp, A., Lamond, A. I. & Cohen, P. T. W., May 2003, In : Journal of Cell Science. 116, 10, p. 1905-1913 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro

Rocha, S., Campbell, K. J., Roche, K. C. & Perkins, N. D., Sep 2003, In : BMC Molecular Biology. 4, 9

Research output: Contribution to journalArticle

50 Citations (Scopus)