Gene Regulation and Expression

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2003

The peroxisome proliferator activated receptor δ is required for the differentiation of THP-1 monocytic cells by phorbol ester

Vosper, H., Khoudoli, G. A. & Palmer, C. N. A., 11 Dec 2003, In : Nuclear Receptor. 1, 10 p., 9.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
46 Downloads (Pure)

The role of the replication licensing system in cell proliferation and cancer

Shreeram, S. & Blow, J., 2003, In : Progress in Cell Cycle Research. 5, p. 287-293 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Time-lapse Imaging Reveals Dynamic Relocalization of PP1γ throughout the Mammalian Cell Cycle

Trinkle-Mulcahy, L., Andrews, P. D., Wickramasinghe, S., Sleeman, J., Prescott, A., Lam, Y. W., Lyon, C., Swedlow, J. R. & Lamond, A. I., 1 Jan 2003, In : Molecular Biology of the Cell. 14, 1, p. 107-117 11 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)
2004

3D3/lyric: A novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus

Sutherland, H. G. E., Lam, Y. W., Briers, S., Lamond, A. I. & Bickmore, W. A., 10 Mar 2004, In : Experimental Cell Research. 294, 1, p. 94-105 12 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Active repression of antiapoptotic gene expression by RelA(p65) NF-kB

Campbell, K. J., Rocha, S. & Perkins, N. D., Mar 2004, In : Molecular Cell. 13, 6, p. 853-865 13 p.

Research output: Contribution to journalArticle

331 Citations (Scopus)

A proteomic study of SUMO-2 target proteins

Vertegaal, A. C. O., Ogg, S. C., Jaffray, E., Rodriguez, M. S., Hay, R. T., Andersen, J. S., Mann, M. & Lamond, A. I., 6 Aug 2004, In : Journal of Biological Chemistry. 279, 32, p. 33791-33798 8 p.

Research output: Contribution to journalArticle

Open Access
176 Citations (Scopus)

Aurora B regulates MCAK at the mitotic centromere

Andrews, P. D., Ovechkina, Y., Morrice, N., Wagenbach, M., Duncan, K., Wordeman, L. & Swedlow, J. R., 2004, In : Developmental Cell. 6, 2, p. 253-268 16 p.

Research output: Contribution to journalArticle

396 Citations (Scopus)

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

Jares, P., Luciani, M. G. & Blow, J. J., 2004, In : BMC Molecular Biology. 5, p. 1-14 14 p., 5.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus

Luciani, M. G., Oehlmann, M. & Blow, J. J., 1 Dec 2004, In : Journal of Cell Science. 117, 25, p. 6019-30 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility

Griffis, E. R., Craige, B., Dimaano, C., Ullman, K. S. & Powers, M. A., 2004, In : Molecular Biology of the Cell. 15, 4, p. 1991-2002 12 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

DNA replication licensing in somatic and germ cells

Eward, K. L., Obermann, E. C., Shreeram, S., Loddo, M., Fanshawe, T., Williams, C., Jung, H-I., Prevost, A. T., Blow, J. J., Stoeber, K. & Williams, G. H., 2004, In : Journal of Cell Science. 117, Pt 24, p. 5875-86 12 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

Xirodimas, D. P., Saville, M. K., Bourdon, J. C., Hay, R. T. & Lane, D. P., 9 Jul 2004, In : Cell. 118, 1, p. 83-97 15 p.

Research output: Contribution to journalArticle

368 Citations (Scopus)

Mechanical stress induces profound remodelling of keratin filaments and cell junctions in epidermolysis bullosa simplex keratinocytes

Russell, D., Andrews, P. D., James, J. & Lane, E. B., Oct 2004, In : Journal of Cell Science. 117, 22, p. 5233-5243 11 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line

Wicky, C., Alpi, A., Passannante, M., Rose, A., Gartner, A. & Muller, F., 2004, In : Molecular and Cellular Biology. 24, 11, p. 5016-5027 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing

Li, A. & Blow, J. J., 2004, In : Cell Cycle. 3, 4, p. 441-443 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination

Li, A. & Blow, J. J., Mar 2004, In : Nature Cell Biology. 6, 3, p. 260-267 8 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach

Khoudoli, G. A., Porter, I. M., Blow, J. J. & Swedlow, J. R., 9 Sep 2004, In : Proteome Science. 2, 1, 6.

Research output: Contribution to journalArticle

36 Citations (Scopus)

p14 arf promotes small ubiquitin-like modifier conjugation of Werners helicase

Woods, Y. L., Xirodimas, D. P., Prescott, A. R., Sparks, A., Lane, D. P. & Saville, M. K., 2004, In : Journal of Biological Chemistry. 279, 48, p. 50157-50166 10 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
85 Citations (Scopus)

Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis

Hutchins, J. R. A., Moore, W. J., Hood, F. E., Wilson, J. S. J., Andrews, P. D., Swedlow, J. R. & Clarke, P. R., Jun 2004, In : Current Biology. 14, 12, p. 1099-1104 6 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells

Leung, A. K. L., Gerlich, D., Miller, G., Lyon, C., Lam, Y. W., Lleres, D., Daigle, N., Zomerdijk, J., Ellenherg, J. & Lamond, A. I., 2004, In : Journal of Cell Biology. 166, 6, p. 787-800 14 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

Saville, M. K., Sparks, A., Xirodimas, D. P., Wardrop, J., Stevenson, L. F., Bourdon, J-C., Woods, Y. L. & Lane, D. P., 1 Oct 2004, In : Journal of Biological Chemistry. 279, 40, p. 42169-42181 13 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Sequence-specific inhibition of small RNA function

Hutvagner, G., Simard, M. J., Mello, C. C. & Zamore, P. D., 2004, In : PLoS Biology. 2, 4, p. e98

Research output: Contribution to journalArticle

533 Citations (Scopus)

Sin mutations alter inherent nucleosome mobility

Flaus, A., Rencurel, C., Ferreira, H., Wiechens, N. & Owen-Hughes, T., 2004, In : The EMBO Journal. 23, 2, p. 343-353 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Structure-based exploration of cyclic dipeptide chitinase inhibitors

Houston, D. R., Synstad, B., Eijsink, V. G. H., Stark, M. J. R., Eggleston, I. M. & van Aalten, D. M. F., 2004, In : Journal of Medicinal Chemistry. 47, 23, p. 5713-20 8 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle

Dewar, H., Tanaka, K., Nasmyth, K. & Tanaka, T. U., 2004, In : Nature. 428, 6978, p. 93-97 5 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)

The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage

Pohler, E., Craig, A. L., Cotton, J., Lawrie, L., Dillon, J. F., Ross, P., Kernohan, N. & Hupp, T. R., 2004, In : Molecular & Cellular Proteomics. 3, 6, p. 534-547 14 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

The development of a CDK2-docking site peptide that inhibits p53 and sensitizes cells to death

Ferguson, M., Luciani, M. G., Finlan, L., Rankin, E. M., Ibbotson, S., Fersht, A. & Hupp, T. R., Jan 2004, In : Cell Cycle. 3, 1, p. 80-89 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner

Wilson, B. J., Bates, G. J., Nicol, S. M., Gregory, D. J., Perkins, N. D. & Fuller-Pace, F. V., 6 Aug 2004, In : BMC Molecular Biology. 5, 15 p., 11.

Research output: Contribution to journalArticle

Open Access
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105 Citations (Scopus)
68 Downloads (Pure)

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation

Oehlmann, M., Score, A. J. & Blow, J. J., 2004, In : Journal of Cell Biology. 165, 2, p. 181-90 10 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

The STAT3 isoforms α and β have unique and specific functions

Maritano, D., Sugrue, M. L., Tininini, S., Dewilde, S., Strobl, B., Fu, X., Murray-Tait, V., Chiarle, R. & Poli, V., Apr 2004, In : Nature Immunology. 5, 4, p. 401-409 9 p.

Research output: Contribution to journalArticle

145 Citations (Scopus)

The yeast elongator histone acetylase requires Sit4-dependent dephosphorylation for toxin-target capacity

Jablonowski, D., Fichtner, L., Stark, M. J. R. & Schaffrath, R., 1 Mar 2004, In : Molecular Biology of the Cell. 15, 3, p. 1459-69 11 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa

Thomson, R. E., Bigley, A. L., Foster, J. R., Jowsey, I. R., Elcombe, C. R., Orton, T. C. & Hayes, J. D., May 2004, In : Journal of Histochemistry & Cytochemistry. 52, 5, p. 653-662 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2005

ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases

Rocha, S. & Perkins, N. D., Jun 2005, In : Cell Cycle. 4, 6, p. 756-9 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

A robust and selective method for the quantification of glycosylphosphatidylinositols in biological samples

MacRae, J. I. & Ferguson, M. A. J., Feb 2005, In : Glycobiology. 15, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

Li, A. & Blow, J. J., Jan 2005, In : The EMBO Journal. 24, 2, p. 395-404 10 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Characterization of hCINAP, a novel coilin-interacting protein by a transcript from the transcription factor TAFIID32 locus

Santama, N., Ogg, S. C., Malekkou, A., Zographos, S. E., Weis, K. & Lamond, A. I., 28 Oct 2005, In : Journal of Biological Chemistry. 280, 43, p. 36429-36441 13 p.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

Larance, M., Ramm, G., Stöckli, J., van Dam, E. M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J. R., Guilhaus, M. & James, D. E., 11 Nov 2005, In : Journal of Biological Chemistry. 280, 45, p. 37803-37813 11 p.

Research output: Contribution to journalArticle

292 Citations (Scopus)

Chromosome bi-orientation on the mitotic spindle

Tanaka, T. U., 2005, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 360, 1455, p. 581-9 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Condensed mitotic chromatin is accessible to transcription factors and chromatin structural protiens

Chen, D., Dundr, M., Wang, C., Leung, A., Lamond, A., Misteli, T. & Huang, S., Jan 2005, In : Journal of Cell Biology. 168, 1, p. 41-54 14 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations

Schofield, P., Chaplain, M. & Hubbard, S., 2005, In : Journal of Theoretical Biology. 237, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35

Chusainow, J., Ajuh, P. M., Trinkle-Mulcahy, L., Sleeman, J. E., Ellenberg, J. & Lamond, A. I., Aug 2005, In : RNA. 11, 8, p. 1201-1214 14 p.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

Functional domains of the Xenopus replication licensing factor Cdt1

Ferenbach, A., Li, A., Brito-Martins, M. & Blow, J. J., 2005, In : Nucleic Acids Research. 33, 1, p. 316-24 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Glutathione transferases

Hayes, J. D., Flanagan, J. U. & Jowsey, I. R., 2005, In : Annual Review of Pharmacology and Toxicology. 45, p. 51-88 38 p.

Research output: Contribution to journalArticle

2460 Citations (Scopus)

Interaction of U-box E3 ligase SNEV with PSMB4, the β7 subunit of the 20 S proteasome

Löscher, M., Fortschegger, K., Ritter, G., Wostry, M., Voglauer, R., Schmid, J. A., Watters, S., Rivett, A. J., Ajuh, P. M., Lamond, A. I., Katinger, H. & Grillari, J., 1 Jun 2005, In : Biochemical Journal. 388, 2, p. 593-603 11 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Kinetochore capture and bi-orientation on the mitotic spindle

Tanaka, T. U., Stark, M. J. R. & Tanaka, K., 2005, In : Nature Reviews Molecular Cell Biology. 6, 12, p. 929-42 14 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Mannosyl-diinositolphospho-ceramide, the major yeast plasma membrane sphingolipid, governs toxicity of Kluyveromyces lactis zymocin

Zink, S., Mehlgarten, C., Kitamoto, H. K., Nagase, J., Jablonowski, D., Dickson, R. C., Stark, M. J. R. & Schaffrath, R., May 2005, In : Eukaryotic Cell. 4, 5, p. 879-89 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Molecular mechanisms of kinetochore capture by spindle microtubules

Tanaka, K., Mukae, N., Dewar, H., Breugel, M. V., James, E. K., Prescott, A. R., Antony, C. & Tanaka, T. U., 2005, In : Nature. 434, 7036, p. 987-994 8 p.

Research output: Contribution to journalArticle

204 Citations (Scopus)

Nucleolar proteome dynamics

Andersen, J. S., Lam, Y. W., Leung, A. K. L., Ong, S. E., Lyon, C. E., Lamond, A. I. & Mann, M., 6 Jan 2005, In : Nature. 433, 7021, p. 77-83 7 p.

Research output: Contribution to journalArticle

840 Citations (Scopus)

p53 isoforms can regulate p53 transcriptional activity

Bourdon, J. C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K. & Lane, D. P., 15 Sep 2005, In : Genes & Development. 19, 18, p. 2122-2137 16 p.

Research output: Contribution to journalArticle

558 Citations (Scopus)