Gene Regulation and Expression

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2005

P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner

Fox, A. H., Bond, C. S. & Lamond, A. I., 1 Nov 2005, In : Molecular Biology of the Cell. 16, 11, p. 5304-5315 12 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions

Pendle, A. F., Clark, G. P., Boon, R., Lewandowska, D., Lam, Y. W., Andersen, J., Mann, M., Lamond, A. I., Brown, J. W. S. & Shaw, P. J., 2005, In : Molecular Biology of the Cell. 16, 1, p. 260-269 10 p.

Research output: Contribution to journalArticle

278 Citations (Scopus)

Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

Rocha, S., Garrett, M. D., Campbell, K. J., Schumm, K. & Perkins, N. D., Mar 2005, In : EMBO Journal. 24, 6, p. 1157-1169 13 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

RNA-polymerase-I-directed rDNA transcription, life and works

Russell, J. & Zomerdijk, J. C. B. M., 2005, In : Trends in Biochemical Sciences. 30, 2, p. 87-96 10 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly

Grillari, J., Ajuh, P., Stadler, G., Löscher, M., Voglauer, R., Ernst, W., Chusainow, J., Eisenhaber, F., Pokar, M., Fortschegger, K., Grey, M., Lamond, A. I. & Katinger, H., 1 Nov 2005, In : Nucleic Acids Research. 33, 21, p. 6868-6883 16 p.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)

Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1

Shen, L., Liu, H., Dong, C., Xirodimas, D., Naismith, J. H. & Hay, R. T., Apr 2005, In : The EMBO Journal. 24, 7, p. 1341-1351 11 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes

MacRae, J. I., Acosta-Serrano, A., Morrice, N. A., Mehlert, A. & Ferguson, M. A. J., 1 Apr 2005, In : Journal of Biological Chemistry. 280, 13, p. 12201-12211 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor

Blair, D. E., Schuettelkopf, A. W., MacRae, J. I., van Aalten, D. M. F. & Thornton, J. (ed.), 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 43, p. 15429-15434 6 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter

Friedrich, J. K., Panov, K. I., Cabart, P., Russell, J. & Zomerdijk, J. C. B. M., 2005, In : Journal of Biological Chemistry. 280, 33, p. 29551-29558 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

The chromosome cycle: coordinating replication and segregation

Blow, J. J. & Tanaka, T. U., 2005, In : EMBO Reports. 6, 11, p. 1028-34 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

Bates, G. J., Nicol, S. M., Wilson, B. J., Jacobs, A-M. F., Bourdon, J-C., Wardrop, J., Gregory, D. J., Lane, D. P., Perkins, N. D. & Fuller-Pace, F. V., 9 Feb 2005, In : The EMBO Journal. 24, 3, p. 543-553 11 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)

The nucleolus

Lam, Y. W., Trinkle-Mulcahy, L. & Lamond, A. I., 2005, In : Journal of Cell Science. 118, 7, p. 1335-1337 3 p.

Research output: Contribution to journalArticle

Open Access
137 Citations (Scopus)

The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging

Goldberg, I. G., Allan, C., Burel, J-M., Creager, D., Falconi, A., Hochheiser, H., Johnston, J., Mellen, J., Sorger, P. K. & Swedlow, J. R., 2005, In : Genome Biology. 6, 5, R47.

Research output: Contribution to journalArticle

151 Citations (Scopus)

The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcription

Nieduszynski, C. A., Blow, J. J. & Donaldson, A. D., 2005, In : Nucleic Acids Research. 33, 8, p. 2410-20 11 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number

Roper, J. R., Guther, M. L. S., MacRae, J. I., Prescott, A. R., Hallyburton, I., Acosta-Serrano, A. & Ferguson, M. A. J., 20 May 2005, In : Journal of Biological Chemistry. 280, 20, p. 19728-19736 9 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

Schumacher, B., Hanazawa, M., Lee, M-H., Nayak, S., Volkmann, K., Hofmann, R., Hengartner, M., Schedl, T. & Gartner, A., Feb 2005, In : Cell. 120, 3, p. 357-368 12 p.

Research output: Contribution to journalArticle

156 Citations (Scopus)

Two-dimensional liquid chromatography/tandem mass spectrometry analysis of Gradiflow fractionated native human plasma

Wasinger, V. C., Locke, V. L., Raftery, M. J., Larance, M., Rothemund, D., Liew, A., Bate, I. & Guilhaus, M., Aug 2005, In : Proteomics. 5, 13, p. 3397-3401 5 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection

Tatham, M. H., Kim, S., Jaffray, E., Song, J., Chen, Y. & Hay, R. T., Jan 2005, In : Nature Structural & Molecular Biology. 12, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)
2006

Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes

Stockdale, C., Flaus, A., Ferreira, H. & Owen-Hughes, T., 2006, In : Journal of Biological Chemistry. 281, 24, p. 16279-88 10 p.

Research output: Contribution to journalArticle

Open Access
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127 Citations (Scopus)
165 Downloads (Pure)

A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160

Ramm, G., Larance, M., Guilhaus, M. & James, D. E., 29 Sep 2006, In : Journal of Biological Chemistry. 281, 39, p. 29174-29180 7 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)

Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription

Panova, T. B., Panov, K. I., Russell, J. & Zomerdijk, J. C. B. M., 2006, In : Molecular and Cellular Biology. 26, 16, p. 5957-5968 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation

Campbell, K. J., Witty, J. M., Rocha, S. & Perkins, N. D., Jan 2006, In : Cancer Research. 66, 2, p. 929-935 7 p.

Research output: Contribution to journalArticle

Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis

Vagnarelli, P., Hudson, D. F., Ribeiro, S. A., Trinkle-Mulcahy, L., Spence, J. M., Lai, F., Farr, C. J., Lamond, A. I. & Earnshaw, W. C., 1 Oct 2006, In : Nature Cell Biology. 8, 10, p. 1133-1142 10 p.

Research output: Contribution to journalArticle

160 Citations (Scopus)

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision

Davidson, I. F., Li, A. & Blow, J. J., Nov 2006, In : Molecular Cell. 24, 3, p. 433-443 11 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Direct observation of DNA distortion by the RSC complex

Lia, G., Praly, E., Ferreira, H., Stockdale, C., Tse-Dinh, Y. C., Dunlap, D., Croquette, V., Bensimon, D. & Owen-Hughes, T., Feb 2006, In : Molecular Cell. 21, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics

Vertegaal, A. C. O., Andersen, J. S., Ogg, S. C., Hay, R. T., Mann, M. & Lamond, A. I., 1 Dec 2006, In : Molecular and Cellular Proteomics. 5, 12, p. 2298-2310 13 p.

Research output: Contribution to journalArticle

Open Access
220 Citations (Scopus)

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress

Woodward, A. M., Göhler, T., Luciani, M. G., Oehlmann, M., Ge, X., Gartner, A., Jackson, D. A. & Blow, J. J., 2006, In : Journal of Cell Biology. 173, 5, p. 673-83 11 p.

Research output: Contribution to journalArticle

236 Citations (Scopus)

Identification of multiple distinct Snf2 subfamilies with conserved structural motifs

Flaus, A., Martin, D. M. A., Barton, G. J. & Owen-Hughes, T., 2006, In : Nucleic Acids Research. 34, 10, p. 2887-905 19 p.

Research output: Contribution to journalArticle

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408 Citations (Scopus)
141 Downloads (Pure)

Identification of novel inhibitors of UDP-Glc 4 '-epimerase, a validated drug target for African sleeping sickness

Urbaniak, M. D., Tabudravu, J. N., Msaki, A., Matera, K. M., Brenk, R., Jaspars, M. & Ferguson, M. A. J., 15 Nov 2006, In : Bioorganic & Medicinal Chemistry Letters. 16, 22, p. 5744-5747 4 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories

Kitamura, E., Blow, J. J. & Tanaka, T. U., 2006, In : Cell. 125, 7, p. 1297-1308 12 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Mating-type locus control of killer toxins from Kluyveromyces lactis and Pichia acaciae

Klassen, R., Jablonowski, D., Stark, M. J. R., Schaffrath, R. & Meinhardt, F., May 2006, In : FEMS Yeast Research. 6, 3, p. 404-13 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications

Pearce, I. G., Chaplain, M. A. J., Schofield, P. G., Anderson, A. R. A. & Hubbard, S. F., 2006, In : Journal of Theoretical Biology. 241, 4, p. 876-886 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

NOPdb: Nucleolar proteome database

Leung, A. K. L., Trinkle-Mulcahy, L., Lam, Y. W., Andersen, J. S., Mann, M. & Lamond, A. I., 1 Jan 2006, In : Nucleic Acids Research. 34, Database Suppl. 1, p. D218-D220 3 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Regulating the licensing of DNA replication origins in metazoa

DePamphilis, M. L., Blow, J. J., Ghosh, S., Saha, T., Noguchi, K. & Vassilev, A., Jun 2006, In : Current Opinion in Cell Biology. 18, 3, p. 231-9 9 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit

Schumm, K., Rocha, S., Caamano, J. & Perkins, N. D., Oct 2006, In : The EMBO Journal. 25, 20, p. 4820-4832 13 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Repo-Man recruits PP1γ to chromatin and is essential for cell viability

Trinkle-Mulcahy, L., Andersen, J., Lam, Y. W., Moorhead, G., Mann, M. & Lamond, A. I., 27 Feb 2006, In : Journal of Cell Biology. 172, 5, p. 679-692 14 p.

Research output: Contribution to journalArticle

Open Access
181 Citations (Scopus)

RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor

Panov, K. I., Panova, T. B., Gadal, O., Nishiyama, K., Saito, T., Russell, J. & Zomerdijk, J. C. B. M., Jul 2006, In : Molecular and Cellular Biology. 26, 14, p. 5436-5448 13 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures

Dürr, H., Flaus, A., Owen-Hughes, T. & Hopfner, K-P., 2006, In : Nucleic Acids Research. 34, 15, p. 4160-7 8 p.

Research output: Contribution to journalArticle

Open Access
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75 Citations (Scopus)
180 Downloads (Pure)

SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes

Fujii, M., Lyakh, L. A., Bracken, C. P., Fukuoka, J., Hayakawa, M., Tsukiyama, T., Soll, S. J., Harris, M., Rocha, S., Roche, K. C., Tominaga, S., Jen, J., Perkins, N. D., Lechleider, R. J. & Roberts, A. B., 8 Dec 2006, In : Molecular Cell. 24, 5, p. 771-83 13 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

SUMO protease SENP1 induces isomerization of the scissile peptide bond

Shen, L., Tatham, M. H., Dong, C., Zagorska, A., Naismith, J. H. & Hay, R. T., Dec 2006, In : Nature Structural & Molecular Biology. 13, 12, p. 1069-1077 9 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

The DNA repair helicases XPD and FancJ have essential iron-sulfur domains

Rudolf, J., Makrantoni, V., Ingledew, W. J., Stark, M. J. R. & White, M. F., 15 Sep 2006, In : Molecular Cell. 23, 6, p. 801-8 8 p.

Research output: Contribution to journalArticle

235 Citations (Scopus)

The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin

Hastie, C. J., Vázquez-Martin, C., Philp, A., Stark, M. J. R. & Cohen, P. T. W., Jul 2006, In : FEBS Journal. 273, 14, p. 3322-34 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology

MacRae, J. I., Obado, S. O., Turnock, D. C., Roper, J. R., Kierans, M., Kelly, J. M. & Ferguson, M. A. J., May 2006, In : Molecular and Biochemical Parasitology. 147, 1, p. 126-136 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

UBF activates RNA polymerase I transcription by stimulating promoter escape

Panov, K. I., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M., 2006, In : The EMBO Journal. 25, 14, p. 3310-3322 13 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

UV-induced fragmentation of Cajal bodies

Cioce, M., Boulon, S., Matera, A. G. & Lamond, A. I., 6 Nov 2006, In : Journal of Cell Biology. 175, 3, p. 401-413 13 p.

Research output: Contribution to journalArticle

Open Access
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57 Citations (Scopus)
326 Downloads (Pure)
2007

A cell cycle regulatory network controlling NF-B subunit activity and function

Barre, B. & Perkins, N., 2007, In : The EMBO Journal. 26, 23, p. 4841-4855 15 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins

Lam, Y. W., Lamond, A. I., Mann, M. & Andersen, J. S., May 2007, In : Current Biology. 17, 9, p. 749-760 12 p.

Research output: Contribution to journalArticle

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242 Citations (Scopus)
284 Downloads (Pure)

A novel role for the yeast protein kinase Dbf2p in vacuolar H+-ATPase function and sorbic acid stress tolerance

Makrantoni, V., Dennison, P., Stark, M. J. R. & Coote, P. J., Dec 2007, In : Microbiology. 153, p. 4016-4026 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

Gorski, J. J., Pathak, S., Panov, K., Kasciukovic, T., Panova, T., Russell, J. & Zomerdijk, J. C. B. M., Mar 2007, In : The EMBO Journal. 26, 6, p. 1560-1568 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Bod1, a novel kinetochore protein required for chromosome biorientation

Porter, I. M., McClelland, S. E., Khoudoli, G. A., Hunter, C. J., Andersen, J. S., McAinsh, A. D., Blow, J. J. & Swedlow, J. R., 15 Oct 2007, In : Journal of Cell Biology. 179, 2, p. 187-197 11 p.

Research output: Contribution to journalArticle

Open Access
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40 Citations (Scopus)
263 Downloads (Pure)