Gene Regulation and Expression

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2007

Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing

Jantsch, V., Tang, L., Pasierbek, P., Penkner, A., Nayak, S., Baudrimont, A., Schedl, T., Gartner, A. & Loidl, J., Dec 2007, In : Molecular Biology of the Cell. 18, 12, p. 4911-4920 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Characterization of a new SUMO-1 nuclear body (SNB) enriched in pCREB, CBP, c-Jun in neuron-like UR61 cells

Navascues, J., Bengoechea, R., Tapia, O., Vaqué, J. P., Lafarga, M. & Berciano, M. T., 2007, In : Chromosoma. 116, 5, p. 441-451 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Disease induced dynamics in host-parasitoid systems: chaos and coexistence

Preedy, K. F., Schofield, P. G., Chaplain, M. A. J. & Hubbard, S. F., 2007, In : Journal of the Royal Society Interface. 4, 14, p. 463-471 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress

Ge, X. Q., Jackson, D. A. & Blow, J. J., 15 Dec 2007, In : Genes & Development. 21, 24, p. 3331-3341 11 p.

Research output: Contribution to journalArticle

341 Citations (Scopus)

ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing

Gillespie, P. J., Khoudoli, G. A., Stewart, G., Swedlow, J. R. & Blow, J. J., 9 Oct 2007, In : Current Biology. 17, 19, p. 1657-62 6 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Evaluating performance in three-dimensional fluorescence microscopy

Murray, J. M., Appleton, P. L., Swedlow, J. R. & Waters, J. C., Dec 2007, In : Journal of Microscopy. 228, 3, p. 390-405 16 p.

Research output: Contribution to journalArticle

Open Access
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85 Citations (Scopus)
248 Downloads (Pure)

FRG1P-mediated aggregation of proteins involved in pre-mRNA processing

van Koningsbruggen, S., Straasheijm, K. R., Sterrenburg, E., de Graaf, N., Dauwerse, H. G., Frants, R. R. & van der Maarel, S. M., 2007, In : Chromosoma. 116, 1, p. 53-64 12 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Gene regulation under low oxygen: holding your breath for transcription

Rocha, S., Aug 2007, In : Trends in Biochemical Sciences. 32, 8, p. 389-97 9 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms

Ferreira, H., Flaus, A. & Owen-Hughes, T., 30 Nov 2007, In : Journal of Molecular Biology. 374, 3, p. 563-579 17 p.

Research output: Contribution to journalArticle

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95 Citations (Scopus)
198 Downloads (Pure)

Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability

Ferreira, H., Somers, J., Webster, R., Flaus, A. & Owen-Hughes, T., 2007, In : Molecular and Cellular Biology. 27, 11, p. 4037-48 12 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Integrating cell-signalling pathways with NF-κB and IKK function

Perkins, N. D., Jan 2007, In : Nature Reviews Molecular Cell Biology. 8, 1, p. 49-62 14 p.

Research output: Contribution to journalArticle

1657 Citations (Scopus)

Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores

King, E., Rachidi, N., Morrice, N., Hardwick, K. G. & Stark, M. J. R., 2007, In : Genes & Development. 21, 10, p. 1163-1168 6 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Kinetochore-microtubule interaction during S phase in Saccharomyces cerevisiae

Kitamura, E., Tanaka, K., Kitamura, Y. & Tanaka, T. U., 15 Dec 2007, In : Genes & Development. 21, 24, p. 3319-3330 12 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord

Wilcock, A. C., Swedlow, J. R. & Storey, K. G., 15 May 2007, In : Development. 134, 10, p. 1943-54 12 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Molecular mechanisms of microtubule-dependent kinetochore transport toward spindle poles

Tanaka, K., Kitamura, E., Kitamura, Y. & Tanaka, T. U., 2007, In : Journal of Cell Biology. 178, 2, p. 269-81 13 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism

Maure, J-F., Kitamura, E. & Tanaka, T. U., 18 Dec 2007, In : Current Biology. 17, 24, p. 2175-2182 8 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

'Open minded' cells: how cells can change fate

Costa, S. & Shaw, P., Mar 2007, In : Trends in Cell Biology. 17, 3, p. 101-6 6 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-B- and p53-regulated gene targets

McTavish, N., Copeland, L. A., Saville, M. K., Perkins, N. D. & Spruce, B. A., 2007, In : Cell Death & Differentiation. 14, 9, p. 1700-1710 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Pyrosequencing positions nucleosomes precisely

Owen-Hughes, T. & Engeholm, M., 27 Jun 2007, In : Genome Biology. 8, 6, p. 217

Research output: Contribution to journalArticle

2 Citations (Scopus)

Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases

Fox, G. C., Shafiq, M., Briggs, D. C., Knowles, P. P., Collister, M., Didmon, M. J., Makrantoni, V., Dickinson, R. J., Hanrahan, S., Totty, N., Stark, M. J. R., Keyse, S. M. & McDonald, N. Q., 2007, In : Nature. 447, 7143, p. 487-492 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP1

Roche, K. C., Rocha, S., Bracken, C. P. & Perkins, N. D., 5 Jul 2007, In : Oncogene. 26, 31, p. 4523-30 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Screening and characterization of microbial inhibitors against eukaryotic protein phosphatases (PP1 and PP2A)

Ong, S. M., Voo, L. Y. C., Lai, N. S., Stark, M. J. R. & Ho, C. C., Mar 2007, In : Journal of Applied Microbiology. 102, 3, p. 680-92 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore

Griffis, E. R., Stuurman, N. & Vale, R. D., 2007, In : Journal of Cell Biology. 177, 6, p. 1005-15 11 p.

Research output: Contribution to journalArticle

138 Citations (Scopus)

SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1

Jacobs, A-M., Nicol, S. M., Hislop, R. G., Jaffray, E. G., Hay, R. T. & Fuller-Pace, F. V., 30 Aug 2007, In : Oncogene. 26, 40, p. 5866-76 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

SUMO-specific proteases: a twist in the tail

Hay, R. T., Aug 2007, In : Trends in Cell Biology. 17, 8, p. 370-6 7 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)

The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe

Miranda-Saavedra, D., Stark, M. J. R., Packer, J. C., Vivares, C. P., Doerig, C. & Barton, G. J., 2007, In : BMC Genomics. 8, 309.

Research output: Contribution to journalArticle

48 Citations (Scopus)

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

Stevenson, L. F., Sparks, A., Allende-Vega, N., Xirodimas, D. P., Lane, D. & Saville, M. K., 2007, In : The EMBO Journal. 26, 4, p. 976-986 11 p.

Research output: Contribution to journalArticle

178 Citations (Scopus)

The elusive determinants of replication origins

Costa, S. & Blow, J. J., 2007, In : EMBO Reports. 8, 4, p. 332-4 3 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The multifunctional nucleolus

Boisvert, F-M., van Koningsbruggen, S., Navascués, J. & Lamond, A. I., 2007, In : Nature Reviews Molecular Cell Biology. 8, 7, p. 574-585 12 p.

Research output: Contribution to journalArticle

886 Citations (Scopus)

The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G

Ulke-Lemée, A., Trinkle-Mulcahy, L., Chaulk, S., Bernstein, N. K., Morrice, N., Glover, M., Lamond, A. I. & Moorhead, G. B. G., 1 Oct 2007, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 10, p. 1339-1350 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The STAT3 oncogene as a predictive marker of drug resistance

Barré, B., Vigneron, A., Perkins, N., Roninson, I. B., Gamelin, E. & Coqueret, O., 2007, In : Trends in Molecular Medicine. 13, 1, p. 4-11 8 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

The tagged microarray marker (TAM) method for high-throughput detection of single nucleotide and indel polymorphisms

Jing, R., Bolshakov, V. & Flavell, A. J., 2007, In : Nature Protocols. 2, 1, p. 168-177 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Toward a high-resolution view of nuclear dynamics

Trinkle-Mulcahy, L. & Lamond, A. I., 2007, In : Science. 318, 5855, p. 1402-1407 6 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Transcriptional profiling of the LPS induced NF-kappaB response in macrophages

Sharif, O., Bolshakov, V. N., Raines, S., Newham, P. & Perkins, N. D., 2007, In : BMC Immunology. 8, p. 1

Research output: Contribution to journalArticle

227 Citations (Scopus)

Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins

Gonsalvez, G. B., Tian, L., Ospina, J. K., Boisvert, F. M., Lamond, A. I. & Matera, A. G., 27 Aug 2007, In : Journal of Cell Biology. 178, 5, p. 733-740 8 p.

Research output: Contribution to journalArticle

Open Access
100 Citations (Scopus)
2008

Argonaute proteins: key players in RNA silencing

Hutvagner, G. & Simard, M. J., Jan 2008, In : Nature Reviews Molecular Cell Biology. 9, 1, p. 22-32 11 p.

Research output: Contribution to journalArticle

778 Citations (Scopus)

ATP-dependent looping of DNA by ISWI

Lia, G., Indrieri, M., Owen-Hughes, T., Finzi, L., Podesta, A., Milani, P. & Dunlap, D., Sep 2008, In : Journal of Biophotonics. 1, 4, p. 280-286 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A versatile partner of eukaryotic protein complexes that is involved in multiple biological processes: Kti11/Dph3

Baer, C., Zabel, R., Liu, S., Stark, M. J. R. & Schaffrath, R., Sep 2008, In : Molecular Microbiology. 69, 5, p. 1221-1233 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis

Greiss, S., Hall, J., Ahmed, S. & Gartner, A., 15 Oct 2008, In : Genes & Development. 22, 20, p. 2831-2842 12 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes

Yip, M. F., Ramm, G., Larance, M., Hoehn, K. L., Wagner, M. C., Guilhaus, M. & James, D. E., 5 Nov 2008, In : Cell Metabolism. 8, 5, p. 384-398 15 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Cell cycle progression requires the CDC-48(UFD-1/NPL-4) complex for efficient DNA replication

Mouysset, J., Deichsel, A., Moser, S., Hoege, C., Hyman, A. A., Gartner, A. & Hoppe, T., 2 Sep 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12879-12884 6 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity

Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J., 1 Apr 2008, In : Cancer Research. 68, 7, p. 2409-2418 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Correction: Human topoisomerase 2 alpha conjugates with SUMO-2 (vol 68, pg 2409, 2008)

Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J., 15 Apr 2008, In : Cancer Research. 68, 8, p. 3076-3076 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Discovery, in vivo activity and mechanism of action of a small-molecule p53 activator

Lain, S., Hollick, J. J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Mathers, J., Holland, S. J., Stark, M. J. R., Pass, G., Woods, J., Lane, D. P. & Westwood, N. J., 6 May 2008, In : Cancer Cell. 13, 5, p. 454-463 10 p.

Research output: Contribution to journalArticle

366 Citations (Scopus)

Displacement affinity chromatography of protein phosphatase one (PP1) complexes

Moorhead, G. B. G., Trinkle-Mulcahy, L., Nimick, M., De Wever, V., Campbell, D. G., Gourlay, R., Lam, Y. W. & Lamond, A. I., 1 Jan 2008, In : BMC Biochemistry. 9, 1

Research output: Contribution to journalArticle

49 Citations (Scopus)

Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines

Liovic, M., Lee, B., Tomic-Canic, M., D'Alessandro, M., Bolshakov, V. N. & Lane, E. B., 2008, In : Experimental Cell Research. 314, 10, p. 2066-2075 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine

Seifert, A., Allan, L. A. & Clarke, P. R., Dec 2008, In : FEBS Journal. 275, 24, p. 6268-6280 13 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Germline survival and apoptosis

Gartner, A., Boag, P. R. & Blackwell, T. K., 1 Jan 2008, In : WormBook. p. 1-20 20 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes

Trinkle-Mulcahy, L., Boulon, S., Lam, Y. W., Urcia, R., Boisvert, F-M., Vandermoere, F., Morrice, N. A., Swift, S., Rothbauer, U., Leonhardt, H. & Lamond, A., 20 Oct 2008, In : Journal of Cell Biology. 183, 2, p. 223-239 17 p.

Research output: Contribution to journalArticle

Open Access
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321 Citations (Scopus)
324 Downloads (Pure)

In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy

Matic, I., van Hagen, M., Schimmel, J., Macek, B., Ogg, S. C., Tatham, M. H., Hay, R. T., Lamond, A. I., Mann, M. & Vertegaal, A. C. O., 1 Jan 2008, In : Molecular & Cellular Proteomics. 7, 1, p. 132-144 13 p.

Research output: Contribution to journalArticle

197 Citations (Scopus)