Gene Regulation and Expression

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1990

Synthesis and applications of oligoribonucleotides with selected 2′-o-methylation using the 2′-o-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting group

Beijer, B., Sulston, I., Sproat, B. S., Rider, P., Lamond, A. I. & Neuner, P., 11 Sep 1990, In : Nucleic Acids Research. 18, 17, p. 5143-5151 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly

Barabino, S. M. L., Blencowe, B. J., Ryder, U., Sproat, B. S. & Lamond, A. I., 19 Oct 1990, In : Cell. 63, 2, p. 293-302 10 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei

Zomerdijk, J. C. B. M., Ouellette, M., ten Asbroek, A. L. M. A., Kieft, R., Bommer, A. M. M., Clayton, C. E. & Borst, P., 1990, In : EMBO Journal. 9, 9, p. 2791-2801 11 p.

Research output: Contribution to journalArticle

The trimethylguanosine cap is a nuclear targeting signal for snRNPs

Lamond, A. I., Dec 1990, In : Trends in Biochemical Sciences. 15, 12, p. 451-452 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1989

Antisense probing of the human U4 U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides

Blencowe, B. J., Sproat, B. S., Ryder, U., Barabino, S. & Lamond, A. I., 3 Nov 1989, In : Cell. 59, 3, p. 531-539 9 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)
78 Citations (Scopus)

DNA replication and its control

Blow, J. J., Apr 1989, In : Current Opinion in Cell Biology. 1, 2, p. 263-267 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases

Sproat, B. S., Lamond, A. I., Beijer, B., Neuner, P. & Ryder, U., 11 May 1989, In : Nucleic Acids Research. 17, 9, p. 3373-3386 14 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)

Kluyveromyces lactis toxin does not inhibit yeast adenylyl cyclase

White, J. H., Butler, A. R. & Stark, M. J. R., 19 Oct 1989, In : Nature. 341, 6243, p. 666-668 3 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Mapping U2 snRNP-pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA

Barabino, S. M. L., Sproat, B. S., Ryder, U., Blencowe, B. J. & Lamond, A. I., 1 Dec 1989, In : EMBO Journal. 8, 13, p. 4171-4178 8 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Nuclear structure and the control of DNA replication in the Xenopus embryo

Blow, J. J., Sheehan, M. A., Watson, J. V. & Laskey, R. A., 1989, In : Journal of Cell Science. Supplement. 12, p. 183-195 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Probing the structure and function of U2 snRNP with antisense oligonucleotides made of 2′-OMe RNA

Lamond, A. I., Sproat, B., Ryder, U. & Hamm, J., 28 Jul 1989, In : Cell. 58, 2, p. 383-390 8 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Remarkable similarities between yeast and mammalian protein phosphatases

Cohen, P., Schelling, D. L. & Stark, M. J. R., 3 Jul 1989, In : FEBS Letters. 250, 2, p. 601-606 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

Mills, A. D., Blow, J. J., White, J. G., Amos, W. B., Wilcock, D. & Laskey, R. A., Nov 1989, In : Journal of Cell Science. 94 , 3, p. 471-477 7 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)

S phase of the cell cycle

Laskey, R. A., Fairman, M. P. & Blow, J. J., 3 Nov 1989, In : Science. 246, 4930, p. 609-614 6 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)

Tetrahymena telomerase contains an internal RNA template

Lamond, A. I., Jun 1989, In : Trends in Biochemical Sciences. 14, 6, p. 202-204 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The role of cyclin synthesis, modification and destruction in the control of cell division

Minshull, J., Pines, J., Golsteyn, R., Standart, N., Mackie, S., Colman, A., Blow, J., Ruderman, J. V., Wu, M. & Hunt, T., Feb 1989, In : Journal of Cell Science. 1989, Supplement 12, p. 77-97 21 p.

Research output: Contribution to journalArticle

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111 Citations (Scopus)
135 Downloads (Pure)

Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis

Minshull, J., Blow, J. J. & Hunt, T., 24 Mar 1989, In : Cell. 56, 6, p. 947-956 10 p.

Research output: Contribution to journalArticle

282 Citations (Scopus)
1988

Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial

Chung, S. C. S., Leung, J. W. C., Steele, R. J. C., Crofts, T. J. & Li, A. K., 1988, In : BMJ (Clinical Research Ed.). 296, 6637, p. 1631-1633 3 p.

Research output: Contribution to journalArticle

186 Citations (Scopus)

Eukaryotic DNA replication reconstituted outside the cell

Blow, J. J., May 1988, In : BioEssays. 8, 5, p. 149-152 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Resolution of sequence discrepancies in the ORF1 region of the Kluyveromyces lactis plasmid k1

Stark, M. J. R., 25 Jan 1988, In : Nucleic Acids Research. 16, 2, p. 771 1 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

RNA editing and the mysterious undercover genes of trypanosomatid mitochondria

Lamond, A. I., Aug 1988, In : Trends in Biochemical Sciences. 13, 8, p. 283-284 2 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein.

Lamond, A. I., Konarska, M. M., Grabowski, P. J. & Sharp, P. A., 1 Jan 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 2, p. 411-415 5 p.

Research output: Contribution to journalArticle

Open Access
115 Citations (Scopus)

Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs

Sheehan, M. A., Mills, A. D., Sleeman, A. M., Laskey, R. A. & Blow, J. J., Jan 1988, In : Journal of Cell Biology. 106, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)
1987

A mutational analysis of spliceosome assembly: evidence for splice site collaboration during spliceosome formation.

Lamond, A. I., Konarska, M. M. & Sharp, P. A., Aug 1987, In : Genes & Development. 1, 6, p. 532-543 12 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Chromosome replication in cell-free systems from Xenopus eggs

Blow, J. J., Dilworth, S. M., Dingwall, C., Mills, A. D. & Laskey, R. A., 15 Dec 1987, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 317, 1187, p. 483-494 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Hepatic metastases in Hong Kong Chinese: evidence for an East-West difference in gastric cancer

Steele, R. J. C., Chung, S. C., Li, A. K. & Crofts, T. J., 1987, In : Annals of the Royal College of Surgeons of England. 69, 2, p. 61-63 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei

Laird, P. W., Zomerdijk, J. C. B. M., de Korte, D. & Borst, P., 1987, In : EMBO Journal. 6, 4, p. 1055-1062 8 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Molecular cloning and over-expression of the glyoxylate bypass operon from Escherichia coli ML308

el-Mansi, E. M., MacKintosh, C., Duncan, K., Holms, W. H. & Nimmo, H. G., 1987, In : Biochemical Journal. 242, 3, p. 661-665 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system

Blow, J. J. & Watson, J. V., Jul 1987, In : EMBO Journal. 6, 7, p. 1997-2002 6 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Splicing of messenger RNA precursors

Sharp, P. A., Konarska, M. M., Grabowski, P. J., Lamond, A. I., Marciniak, R. & Seiler, S. R., 1987, In : Cold Spring Harbor Symposia on Quantitative Biology. 52, p. 277-285 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Two cases of eosinophilic enteritis presenting as large bowel perforation and small bowel haemorrhage

Steele, R. J. C., Mok, S. D., Crofts, T. J. & Li, A. K., 1987, In : Australian and New Zealand Journal of Surgery. 57, 5, p. 335-336 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
1986

Alteration of the growth-rate-dependent regulation of Escherichia coli tyrT expression by promoter mutations

Travers, A. A., Lamond, A. I. & Weeks, J. R., 5 May 1986, In : Journal of Molecular Biology. 189, 1, p. 251-255 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

Blow, J. J. & Laskey, R. A., 21 Nov 1986, In : Cell. 47, 4, p. 577-587 11 p.

Research output: Contribution to journalArticle

431 Citations (Scopus)
1985

Genetically separable functional elements mediate the optimal expression and stringent regulation of a bacterial tRNA gene

Lamond, A. I. & Travers, A. A., Feb 1985, In : Cell. 40, 2, p. 319-326 8 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle.

Rabbitts, P. H., Watson, J. V., Lamond, A., Forster, A., Stinson, M. A., Evan, G., Fischer, W., Atherton, E., Sheppard, R. & Rabbitts, T. H., 1 Aug 1985, In : EMBO Journal. 4, 8, p. 2009-2015 7 p.

Research output: Contribution to journalArticle

196 Citations (Scopus)

Supercoiling response of a bacterial tRNA gene.

Lamond, A. I., 1 Feb 1985, In : EMBO Journal. 4, 2, p. 501-507 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
1983

Requirement for an upstream element for optimal transcription of a bacterial tRNA gene

Lamond, A. I. & Travers, A. A., 15 Sep 1983, In : Nature. 305, 5931, p. 248-250 3 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

RNA polymerase interactions with the upstream region of the E. coli tyrT promoter

Travers, A. A., Lamond, A. I., Mace, H. A. F. & Berman, M. L., Nov 1983, In : Cell. 35, 1, p. 265-273 9 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
1982

Inter-replicon transposition of Tn1/3 occurs in two sequential genetically separable steps

Kitts, P. A., Lamond, A. & Sherratt, D. J., 18 Feb 1982, In : Nature. 295, 5850, p. 626-628 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

ppGpp regulates the binding of two RNA polymerase molecules to the tyrT promoter

Travers, A. A., Lamond, A. I. & Mace, H. A. F., 25 Aug 1982, In : Nucleic Acids Research. 10, 16, p. 5043-5057 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)