Gene Regulation and Expression

  • United Kingdom

Research Output

Filter
Article

Analysis of intra-specific somatic hybrids of potato (Solanum tuberosum) using simple sequence repeats

Provan, J., Kumar, A., Shepherd, L., Powell, W. & Waugh, R., Dec 1996, In : Plant Cell Reports. 16, 3-4, p. 196-199 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel Syndrome

Llorens-Agost, M., Luessing, J., van Beneden, A., Eykelenboom, J., O'Reilly, D., Bicknell, L. S., Reynolds, J. J., van Koegelenberg, M., Hurles, M. E., Brady, A. F., Jackson, A. P., Stewart, G. S. & Lowndes, N. F., Dec 2018, In : Human Mutation. 39, 12, p. 1847-1853 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
93 Downloads (Pure)

Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins

Lam, Y. W., Lamond, A. I., Mann, M. & Andersen, J. S., May 2007, In : Current Biology. 17, 9, p. 749-760 12 p.

Research output: Contribution to journalArticle

File
242 Citations (Scopus)
287 Downloads (Pure)

Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes

Stockdale, C., Flaus, A., Ferreira, H. & Owen-Hughes, T., 2006, In : Journal of Biological Chemistry. 281, 24, p. 16279-88 10 p.

Research output: Contribution to journalArticle

Open Access
File
127 Citations (Scopus)
166 Downloads (Pure)

Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA

Djupedal, I., Kos-Braun, I. C., Mosher, R. A., Soderholm, N., Simmer, F., Hardcastle, T. J., Fender, A., Heidrich, N., Kagansky, A., Bayne, E., Wagner, E. G. H., Baulcombe, D. C., Allshire, R. C. & Ekwall, K., 16 Dec 2009, In : EMBO Journal. 28, 24, p. 3832-3844 13 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Analysis of the response of Saccharomyces cerevisiae cells to Kluyveromyces lactis toxin

Butler, A. R., White, J. H. & Stark, M. J. R., 1 Jul 1991, In : Journal of General Microbiology. 137, 7, p. 1749-1757 9 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Analysis of the SUMO2 proteome during HSV-1 Infection

Sloan, E., Tatham, M. H., Groslambert, M., Glass, M., Orr, A., Hay, R. T. & Everett, R. D., 22 Jul 2015, In : PLoS Pathogens. 11, 7, 34 p., e1005059.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export

Kendirgi, F., Barry, D. M., Griffis, E. R., Powers, M. A. & Wente, S. R., 2003, In : Journal of Cell Biology. 160, 7, p. 1029-40 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

An evolutionarily conserved, alternatively spliced, intron in the p68/DDX5 DEAD-box RNA helicase gene encodes a novel miRNA

Moore, H. C., Johnston, M., Nicol, S. M., Bourdon, J-C., Thompson, A. M., Hutvagner, G. & Fuller-Pace, F. V., Apr 2011, In : RNA: a Publication of the RNA Society. 17, 4, p. 555-562 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A new role for Ran in ensuring precise duplication of chromosomal DNA

Blow, J. J., 2003, In : Cell. 113, 1, p. 2-4 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

An extreme cytoplasmic bottleneck in the modern European cultivated potato (Solanum tuberosum) is not reflected in decreased levels of nuclear diversity

Provan, J., Powell, W., Dewar, H., Bryan, G., Machray, G. C. & Waugh, R., 22 Mar 1999, In : Proceedings of the Royal Society B: Biological Sciences. 266, 1419, p. 633-639 7 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

ANIA: ANnotation and Integrated Analysis of the 14-3-3 interactome

Tinti, M., Madeira, F., Murugesan, G., Hoxhaj, G., Toth, R. & Mackintosh, C., 2014, In : Database: the Journal of Biological Databases and Curation. 2014, 15 p., bat085.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
177 Downloads (Pure)

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

Schmidt, N., Domingues, P., Golebiowski, F., Patzina, C., Tatham, M. H., Hay, R. T. & Hale, B. G., 27 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17399-17408 10 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
72 Downloads (Pure)

An intellectual disability syndrome with single nucleotide variants in O-GlcNAc Transferase

Pravata, V., Omelkova, M., Stavridis, M., Desbiens, C. M., Stephen, H. M., Lefeber, D. J., Gécz, J., Gundogdu, M., Õunap, K., Joss, S., Schwartz, C. E., Wells, L. & van Aalten, D., 20 Feb 2020, In : European Journal of Human Genetics. 9 p.

Research output: Contribution to journalArticle

Open Access
File
33 Downloads (Pure)

An intranucleolar body associated with rDNA

Hutten, S., Prescott, A., James, J., Riesenberg, S., Boulon, S., Lam, Y. W. & Lamond, A. I., Oct 2011, In : Chromosoma. 120, 5, p. 481-499 19 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing

Ajuh, P., Chusainow, J., Ryder, U. & Lamond, A. I., 1 Dec 2002, In : EMBO Journal. 21, 23, p. 6590-6602 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A novel reporter of notch signalling indicates regulated and random notch activation during vertebrate neurogenesis

Vilas-Boas, F., Fior, R., Swedlow, J. R., Storey, K. G. & Henrique, D., 31 Aug 2011, In : BMC Molecular Biology. 9, p. - 16 p., 58.

Research output: Contribution to journalArticle

27 Citations (Scopus)

A novel role for the yeast protein kinase Dbf2p in vacuolar H+-ATPase function and sorbic acid stress tolerance

Makrantoni, V., Dennison, P., Stark, M. J. R. & Coote, P. J., Dec 2007, In : Microbiology. 153, p. 4016-4026 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

Gorski, J. J., Pathak, S., Panov, K., Kasciukovic, T., Panova, T., Russell, J. & Zomerdijk, J. C. B. M., Mar 2007, In : The EMBO Journal. 26, 6, p. 1560-1568 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

A novel 'two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans

Appleyard, M. V. C. L., McPheat, W. L. & Stark, M. J. R., 2000, In : Current Genetics. 37, 6, p. 364-372 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Antagonistic crosstalk between APC and HIF-1 alpha

Nathke, I. & Rocha, S., 15 May 2011, In : Cell Cycle. 10, 10, p. 1545-1547 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Antibody RING-Mediated Destruction of Endogenous Proteins

Ibrahim, A. F. M., Shen, L., Tatham, M. H., Dickerson, D., Prescott, A. R., Abidi, N., Xirodimas, D. P. & Hay, R. T., 25 May 2020, In : Molecular Cell. 12 p.

Research output: Contribution to journalArticle

Open Access
File
14 Downloads (Pure)

Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features

Zomerdijk, J. C. B. M., Kieft, R., Duyndam, M., Shiels, P. G. & Borst, P., 1991, In : Nucleic Acids Research. 19, 7, p. 1359-1368 10 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Antigen receptor control of methionine metabolism in T cells

Sinclair, L. V., Howden, A., Brenes Murillo, A., Spinelli, L., Hukelmann, J., Macintyre, A. N., Liu, X., Thomson, S., Taylor, P., Rathmell, J. C., Locasale, J. W., Lamond, A. & Cantrell, D. A., 27 Mar 2019, In : eLife. 8, p. 1-29 29 p., e44210.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
105 Downloads (Pure)

Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts

Lamm, G. M., Blencowe, B. J., Sparoat, B. S., Iribarren, A. M., Ryder, U. & Lamond, A. I., 25 Jun 1991, In : Nucleic Acids Research. 19, 12, p. 3193-3198 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing

Barabino, S. M. L., Sproat, B. S. & Lamond, A. I., 11 Sep 1992, In : Nucleic Acids Research. 20, 17, p. 4457-4464 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Antisense probing of the human U4 U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides

Blencowe, B. J., Sproat, B. S., Ryder, U., Barabino, S. & Lamond, A. I., 3 Nov 1989, In : Cell. 59, 3, p. 531-539 9 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

APETALA2 control of barley internode elongation

Patil, V., McDermott, H. I., Mcallister, T., Cummins, M., Clara Silva, J., Mollison, E., Meikle, R., Morris, J. A., Hedley, P. E., Waugh, R., Dockter, C., Hansson, M. & McKim, S., 12 Jun 2019, In : Development. 146, 11, p. 1-16 16 p., 170373.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
91 Downloads (Pure)

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

Mishra, A., Oulès, B., Pisco, A. O., Ly, T., Liakath-Ali, K., Walko, G., Viswanathan, P., Tihy, M., Nijjhar, J., Dunn, S-J., Lamond, A. I. & Watt, F. M., 18 Oct 2017, In : eLife. 6, p. 1-20 20 p., e27356.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
209 Downloads (Pure)

A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

Tatham, M. H., Cole, C., Scullion, P., Wilkie, R., Westwood, N. J., Stark, L. A. & Hay, R. T., 1 Feb 2017, In : Molecular & Cellular Proteomics. 16, 2, p. 310-326 17 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
174 Downloads (Pure)

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells

Ly, T., Ahmad, Y., Shlien, A., Soroka, D., Mills, A., Emanuele, M. J., Stratton, M. R. & Lamond, A. I., 4 Mar 2014, In : eLife. 2014, 3, e01630.

Research output: Contribution to journalArticle

Open Access
File
70 Citations (Scopus)
102 Downloads (Pure)

A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58

Westman, B. J., Verheggen, C., Hutten, S., Lam, Y. W., Bertrand, E. & Lamond, A. I., 27 Aug 2010, In : Molecular Cell. 39, 4, p. 618-631 14 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

A proteomic study of SUMO-2 target proteins

Vertegaal, A. C. O., Ogg, S. C., Jaffray, E., Rodriguez, M. S., Hay, R. T., Andersen, J. S., Mann, M. & Lamond, A. I., 6 Aug 2004, In : Journal of Biological Chemistry. 279, 32, p. 33791-33798 8 p.

Research output: Contribution to journalArticle

Open Access
176 Citations (Scopus)

A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture

Dove, B. K., Surtees, R., Bean, T. J. H., Munday, D., Wise, H. M., Digard, P., Carroll, M. W., Ajuh, P., Barr, J. N. & Hiscox, J. A., May 2012, In : Proteomics. 12, 9, p. 1431-1436 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage

Boisvert, F-M., Lam, Y. W., Lamont, D. & Lamond, A. I., Mar 2010, In : Molecular & Cellular Proteomics. 9, 3, p. 457-470 14 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

A quantitative spatial proteomics analysis of proteome turnover in human cells

Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3, M111.011429.

Research output: Contribution to journalArticle

212 Citations (Scopus)

A recQ family DNA helicase gene from Aspergillus nidulans

Appleyard, M. V. C. L., McPheat, W. L. & Stark, M. J. R., 2000, In : Mitochondrial DNA. 11, 3-4, p. 315-319 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A regulated MET3-GLC7 gene fusion provides evidence of a mitotic role for Saccharomyces cerevisiae protein phosphatase 1.

Black, S., Andrews, P. D., Sneddon, A. A. & Stark, M. J. R., 30 Jun 1995, In : Yeast. 11, 8, p. 747-759 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases

Rocha, S. & Perkins, N. D., Jun 2005, In : Cell Cycle. 4, 6, p. 756-9 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Argonaute proteins: key players in RNA silencing

Hutvagner, G. & Simard, M. J., Jan 2008, In : Nature Reviews Molecular Cell Biology. 9, 1, p. 22-32 11 p.

Research output: Contribution to journalArticle

779 Citations (Scopus)

A ribosomal RNA gene promoter at the telomere of a mini-chromosome in Trypanosoma brucei

Zomerdijk, J. C. B. M., Kieft, R. & Borst, P., 1992, In : Nucleic Acids Research. 20, 11, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

A robust and selective method for the quantification of glycosylphosphatidylinositols in biological samples

MacRae, J. I. & Ferguson, M. A. J., Feb 2005, In : Glycobiology. 15, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160

Ramm, G., Larance, M., Guilhaus, M. & James, D. E., 29 Sep 2006, In : Journal of Biological Chemistry. 281, 39, p. 29174-29180 7 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)

A role for paralog-specific sumoylation in histone deacetylase 1 stability

Citro, S., Jaffray, E., Hay, R. T., Seiser, C. & Chiocca, S., 2013, In : Journal of Molecular Cell Biology. 5, 6, p. 416-427 12 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization

Gkikopoulos, T., Schofield, P., Singh, V., Pinskaya, M., Mellor, J., Smolle, M., Workman, J. L., Barton, G. J. & Owen-Hughes, T., 23 Sep 2011, In : Science. 333, 6050, p. 1758-1760 3 p.

Research output: Contribution to journalArticle

174 Citations (Scopus)

A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics

Westman, B. J. & Lamond, A. I., 1 Jan 2011, In : Nucleus. 2, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A role for the adenomatous Polyposis Coli protein in chromosome segregation

Kaplan, K. B., Burds, A. A., Swedlow, J. R., Bekir, S. S., Sorger, P. K. & Näthke, I. S., 2001, In : Nature Cell Biology. 3, 4, p. 429-432 4 p.

Research output: Contribution to journalArticle

445 Citations (Scopus)

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II

Hutten, S., Chachami, G., Winter, U., Melchior, F. & Lamond, A. I., 1 Mar 2014, In : Journal of Cell Science. 127, 5, p. 1065-1078 14 p.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
201 Downloads (Pure)

A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans

González-Huici, V., Wang, B. & Gartner, A., 1 Aug 2017, In : Genetics. 206, 4, p. 1853-1864 12 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
164 Downloads (Pure)

Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies

Geoffroy, M-C., Jaffray, E. G., Walker, K. J. & Hay, R. T., 1 Dec 2010, In : Molecular Biology of the Cell. 21, 23, p. 4227-4239 13 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)