Gene Regulation and Expression

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Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment

Natsume, T., Müller, C. A., Katou, Y., Retkute, R., Gierlinski, M., Araki, H., Blow, J. J., Shirahige, K., Nieduszynski, C. A. & Tanaka, T. U., 6 Jun 2013, In : Molecular Cell. 50, 5, p. 661-674 14 p.

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82 Citations (Scopus)

Kinetochores Generate Microtubules with Distal Plus Ends: Their Roles and Limited Lifetime in Mitosis

Kitamura, E., Tanaka, K., Komoto, S., Kitamura, Y., Antony, C. & Tanaka, T. U., 16 Feb 2010, In : Developmental Cell. 18, 2, p. 248-259 12 p.

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56 Citations (Scopus)

Kluyveromyces lactis killer system: ORF1 of pGKL2 has no function in immunity expression and is dispensable for killer plasmid replication and maintenance

Schaffrath, R., Stark, M. J. R., Gunge, N. & Meinhardt, F., Apr 1992, In : Current Genetics. 21, 4-5, p. 357-363 7 p.

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33 Citations (Scopus)

Kluyveromyces lactis toxin does not inhibit yeast adenylyl cyclase

White, J. H., Butler, A. R. & Stark, M. J. R., 19 Oct 1989, In : Nature. 341, 6243, p. 666-668 3 p.

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35 Citations (Scopus)

Kluyveromyces lactis toxin has an essential chitinase activity

BUTLER, A. R., O'DONNELL, R. W., MARTIN, V. J., GOODAY, G. W. & STARK, M. J. R., 15 Jul 1991, In : European Journal of Biochemistry. 199, 2, p. 483-488 6 p.

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81 Citations (Scopus)

Kluyveromyces lactis zymocin mode of action is linked to RNA polymerase II function via Elongator

Jablonowski, D., Frohloff, F., Fichtner, L., Stark, M. J. R. & Schaffrath, R., Nov 2001, In : Molecular Microbiology. 42, 4, p. 1095-105 11 p.

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59 Citations (Scopus)

Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator

Krutyhołowa, R., Hammermeister, A., Zabel, R., Abdel-Fattah, W., Reinhardt-Tews, A., Helm, M., Stark, M. J. R., Breunig, K. D., Schaffrath, R. & Glatt, S., 21 May 2019, In : Nucleic Acids Research. 47, 9, p. 4814-4830 17 p.

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LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis

Liu, B., Du, H., Rutkowski, R., Gartner, A. & Wang, X., 2012, In : Science. 337, 6092, p. 351-354 4 p.

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62 Citations (Scopus)

Large-scale isolation of Cajal bodies from HeLa cells

Lam, Y. W., Lyon, C. E. & Lamond, A. I., Jul 2002, In : Molecular Biology of the Cell. 13, 7, p. 2461-2473 13 p.

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64 Citations (Scopus)

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

Hong, Y., Sonneville, R., Wang, B., Scheidt, V., Meier, B., Woglar, A., Demetriou, S., Labib, K., Jantsch, V. & Gartner, A., 20 Feb 2018, In : Nature Communications. 9, p. 1-11 11 p., 728.

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9 Citations (Scopus)
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Length-dependent anisotropic scaling of spindle shape

Young, S., Besson, S. & Welburn, J. P. I., 15 Dec 2014, In : Open Biology. 3, 12, p. 1217-1223 7 p.

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13 Citations (Scopus)
111 Downloads (Pure)

LigaSure compared with ligatures and endoclips in experimental appendectomy: How safe is it?

Elemen, L., Tugay, M., Akay, A., Yazir, Y., Ceylan, S., Aydin, S. & Yanar, K., 2010, In : Pediatric Surgery International. 26, 5, p. 539-545 7 p.

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25 Citations (Scopus)

LimsPortal and BonsaiLIMS: development of a lab information management system for translational medicine

Bath, T. G., Bozdag, S., Afzal, V. & Crowther, D., 15 Sep 2011, In : Source code for biology and medicine. 6, p. 9

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6 Citations (Scopus)

Live-cell analysis of kinetochore-microtubule interaction in budding yeast

Tanaka, K., Kitamura, E. & Tanaka, T. U., 2010, In : Methods (San Diego, Calif.). 51, 2, p. 206-13 8 p.

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21 Citations (Scopus)

Live-cell imaging of marked chromosome regions reveals dynamics of mitotic chromosome resolution and compaction

Eykelenboom, J. K., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T. U., 17 May 2018, In : BioRxiv. 53 p.

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Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories

Kitamura, E., Blow, J. J. & Tanaka, T. U., 2006, In : Cell. 125, 7, p. 1297-1308 12 p.

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142 Citations (Scopus)

Live-cell imaging RNAi screen identifies PP2A-B55 alpha and importin-beta 1 as key mitotic exit regulators in human cells

Schmitz, M. H. A., Held, M., Janssens, V., Hutchins, J. R. A., Hudecz, O., Ivanova, E., Goris, J., Trinkle-Mulcahy, L., Lamond, A. I., Poser, I., Hyman, A. A., Mechtler, K., Peters, J-M. & Gerlich, D. W., Sep 2010, In : Nature Cell Biology. 12, 9, p. 886-893 8 p.

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215 Citations (Scopus)

Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis

Eykelenboom, J., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T., 6 May 2019, In : Journal of Cell Biology. 218, 5, p. 1531-1552 22 p.

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4 Citations (Scopus)
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Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J. & Chubb, J. R., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7350-7355 6 p.

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76 Citations (Scopus)

Localisation of splicing snRNPs in mammalian cells

Lamond, A. I. & Carmo-Fonseca, M., 1 Aug 1993, In : Molecular Biology Reports. 18, 2, p. 127-133 7 p.

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53 Citations (Scopus)

Locus-specific proteomics by TChP: targeted chromatin purification

Pourfarzad, F., Aghajanirefah, A., de Boer, E., Ten Have, S., Bryn van Dijk, T., Kheradmandkia, S., Stadhouders, R., Thongjuea, S., Soler, E., Gillemans, N., von Lindern, M., Demmers, J., Philipsen, S. & Grosveld, F., 15 Aug 2013, In : Cell Reports. 4, 3, p. 589-600 12 p.

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20 Citations (Scopus)

Long distance PELDOR measurements on the histone core particle

Ward, R., Bowman, A., El-Mkami, H., Owen-Hughes, T. & Norman, D. G., 4 Feb 2009, In : Journal of the American Chemical Society. 131, 4, p. 1348-+ 3 p.

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24 Citations (Scopus)

Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

Muha, V., Williamson, R., Hills, R., McNeilly, A., McWilliams, T. G., Alonso, J., Schimpl, M., Leney, A. C., Heck, A. J. R., Sutherland, C., Read, K., McCrimmon, R., Brooks, S. P. & van Aalten, D., 27 Nov 2019, In : Open Biology. 9, 11, p. 1-15 15 p.

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Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

Rasmussen, K. D., Jia, G., Johansen, J. V., Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, B. T., Bernard, O. A., Christensen, J. & Helin, K., 1 May 2015, In : Genes and Development. 29, 9, p. 910-922 13 p.

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107 Citations (Scopus)
69 Downloads (Pure)

Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage

Maure, J. F., Moser, S. C., Jaffray, E. G., Alpi, A. F. & Hay, R. T., 17 May 2016, In : Scientific Reports. 6, 10 p., 26178.

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3 Citations (Scopus)
137 Downloads (Pure)

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA

Izumikawa, K., Ishikawa, H., Yoshikawa, H., Fujiyama, S., Watanabe, A., Aburatani, H., Tachikawa, H., Hayano, T., Miura, Y., Isobe, T., Simpson, R. J., Li, L., Min, J. & Takahashi, N., 4 Nov 2019, In : Nucleic Acids Research. 47, 19, p. 10357-10372 16 p.

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MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF

Chang, E. Y., Ferreira, H., Somers, J., Nusinow, D. A., Owen-Hughes, T. & Narlikar, G. J., 23 Dec 2008, In : Biochemistry. 47, 51, p. 13726-13732 7 p.

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37 Citations (Scopus)

Maintenance of distinct melanocyte populations in the interfollicular epidermis

Glover, J. D., Knolle, S., Wells, K. L., Liu, D., Jackson, I. J., Mort, R. L. & Headon, D. J., 1 Jul 2015, In : Pigment Cell and Melanoma Research. 28, 4, p. 476-480 5 p.

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15 Citations (Scopus)

Making sense of transcribing chromatin

Owen-Hughes, T. & Gkikopoulos, T., 1 Jan 2012, In : Current Opinion in Cell Biology.

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16 Citations (Scopus)

Mammalian nuclei become licensed for DNA replication during late telophase

Dimitrova, D. S., Prokhorova, T. A., Blow, J. J., Todorov, I. T. & Gilbert, D. M., 2002, In : Journal of Cell Science. 115, 1, p. 51-59 9 p.

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83 Citations (Scopus)

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery

Carmo-Fonseca, M., Tollervey, D., Pepperkok, R., Barabino, S. M. L., Merdes, A., Brunner, C., Zamore, P. D., Green, M. R., Hurt, E. & Lamond, A. I., 1 Jan 1991, In : EMBO Journal. 10, 1, p. 195-206 12 p.

Research output: Contribution to journalArticle

176 Citations (Scopus)

Mannosyl-diinositolphospho-ceramide, the major yeast plasma membrane sphingolipid, governs toxicity of Kluyveromyces lactis zymocin

Zink, S., Mehlgarten, C., Kitamoto, H. K., Nagase, J., Jablonowski, D., Dickson, R. C., Stark, M. J. R. & Schaffrath, R., May 2005, In : Eukaryotic Cell. 4, 5, p. 879-89 11 p.

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21 Citations (Scopus)

Mapping U2 snRNP-pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA

Barabino, S. M. L., Sproat, B. S., Ryder, U., Blencowe, B. J. & Lamond, A. I., 1 Dec 1989, In : EMBO Journal. 8, 13, p. 4171-4178 8 p.

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40 Citations (Scopus)

Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins

Zachariae, W., Shevchenko, A., Andrews, P. D., Ciosk, R., Galova, M., Stark, M. J. R., Mann, M. & Nasmyth, K., 1998, In : Science. 279, 5354, p. 1216-1219 4 p.

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283 Citations (Scopus)

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

Neubauer, G., King, A., Rappsilber, J., Calvio, C., Watson, M., Ajuh, P., Sleeman, J., Lamond, A. & Mann, M., Sep 1998, In : Nature Genetics. 20, 1, p. 46-50 5 p.

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401 Citations (Scopus)

Mass spectrometry-based immuno-precipitation proteomics - The user's guide

ten Have, S., Boulon, S., Ahmad, Y. & Lamond, A. I., Mar 2011, In : Proteomics. 11, 6, p. 1153-1159 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
15 Citations (Scopus)

Mating-type locus control of killer toxins from Kluyveromyces lactis and Pichia acaciae

Klassen, R., Jablonowski, D., Stark, M. J. R., Schaffrath, R. & Meinhardt, F., May 2006, In : FEMS Yeast Research. 6, 3, p. 404-13 10 p.

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12 Citations (Scopus)

MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J., 1 Apr 2011, In : Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

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94 Citations (Scopus)

Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation

Gambus, A. & Blow, J. J., 15 Apr 2013, In : Cell Cycle. 12, 8, p. 1225-1232 8 p.

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11 Citations (Scopus)

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

Xirodimas, D. P., Saville, M. K., Bourdon, J. C., Hay, R. T. & Lane, D. P., 9 Jul 2004, In : Cell. 118, 1, p. 83-97 15 p.

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368 Citations (Scopus)

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, J. R., Hu, K., Andrews, P. D., Roos, D. S. & Murray, J. M., 19 Feb 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2014-2019 6 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Mechanical stress induces profound remodelling of keratin filaments and cell junctions in epidermolysis bullosa simplex keratinocytes

Russell, D., Andrews, P. D., James, J. & Lane, E. B., Oct 2004, In : Journal of Cell Science. 117, 22, p. 5233-5243 11 p.

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63 Citations (Scopus)

Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta

Almohammed, R., Osborn, K., Ramasubramanyan, S., Perez-Fernandez, I. B. N., Godfrey, A., Mancini, E. J. & Sinclair, A. J., 1 Jun 2018, In : Journal of General Virology. 99, 6, p. 805-817 13 p., 001056.

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Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations

Bueren-Calabuig, J., Bage, M., Cowling, V. & Pisliakov, A., 19 Sep 2019, In : Nucleic Acids Research. 47, 16, p. 8675-8692 18 p., gkz613.

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Mechanism of Hypoxia-Induced NF-kappa B

Culver, C., Sundqvist, A., Mudie, S., Melvin, A., Xirodimas, D. & Rocha, S., 10 Oct 2010, In : Molecular and Cellular Biology. 30, 20, p. 4901-4921 21 p.

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127 Citations (Scopus)

Mechanism of hypoxia-induced NFκB

Melvin, A., Mudie, S. & Rocha, S., 2011, In : Cell Cycle. 10, 6, p. 879-882 4 p.

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25 Citations (Scopus)

Mechanism of ubiquitylation by dimeric RING ligase RNF4

Plechanovova, A., Jaffray, E. G., McMahon, S. A., Johnson, K. A., Navratilova, I., Naismith, J. H. & Hay, R. T., Sep 2011, In : Nature Structural & Molecular Biology. 18, 9, p. 1052-1059 8 p.

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93 Citations (Scopus)

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

Narlikar, G. J., Sundaramoorthy, R. & Owen-Hughes, T., 2013, In : Cell. 154, 3, p. 490-503 14 p.

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286 Citations (Scopus)

Mechanisms mitigating problems with multiple kinetochores on one microtubule in early mitosis

Yue, Z., Komoto, S., Gierlinski, M., Pasquali, D., Kitamura, E. & Tanaka, T. U., 15 Jul 2017, In : Journal of Cell Science. 130, 14, p. 2266-2276 11 p.

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