Gene Regulation and Expression

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Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases

Fang, W., Sanz, A. B., Galan Bartual, S., Wang, B., Ferenbach, A., Farkaš, V., Hurtado-Guerrero, R., Arroyo, J. & van Aalten, D., 10 Apr 2019, In : Nature Communications. 10, 1, p. 1-10 10 p., 1669.

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1 Citation (Scopus)
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Mechanoaccumulative elements of the mammalian actin cytoskeleton

Schiffhauer, E. S., Luo, T., Mohan, K., Srivastava, V., Qian, X., Griffis, E. R., Iglesias, P. A. & Robinson, D. N., 6 Jun 2016, In : Current Biology. 26, 11, p. 1473-1479 7 p.

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31 Citations (Scopus)
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Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo

Miles, W. O., Jaffray, E., Campbell, S. G., Takeda, S., Bayston, L. J., Basu, S. P., Li, M., Raftery, L. A., Ashe, M. P., Hay, R. T. & Ashe, H. L., 15 Sep 2008, In : Genes & Development. 22, 18, p. 2578-2590 13 p.

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32 Citations (Scopus)

Metabolic complexity in the RNA world and implications for the origin of protein synthesis

Gibson, T. J. & Lamond, A. I., 1 Jan 1990, In : Journal of Molecular Evolution. 30, 1, p. 7-15 9 p.

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46 Citations (Scopus)

Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle.

Rabbitts, P. H., Watson, J. V., Lamond, A., Forster, A., Stinson, M. A., Evan, G., Fischer, W., Atherton, E., Sheppard, R. & Rabbitts, T. H., 1 Aug 1985, In : EMBO Journal. 4, 8, p. 2009-2015 7 p.

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195 Citations (Scopus)

Metadata management for high content screening in OMERO

Li, S., Besson, S., Blackburn, C., Carroll, M., Ferguson, R. K., Flynn, H., Gillen, K., Leigh, R., Lindner, D., Linkert, M., Moore, W. J., Ramalingam, B., Rozbicki, E., Rustici, G., Tarkowska, A., Walczysko, P., Williams, E., Allan, C., Burel, J. M., Moore, J. & 1 others, Swedlow, J. R., 1 Mar 2016, In : Methods. 96, p. 27-32 6 p.

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14 Citations (Scopus)
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Methylation of H3K4 is required for inheritance of active transcriptional states

Muramoto, T., Mueller, I., Thomas, G., Melvin, A. & Chubb, J. R., 9 Mar 2010, In : Current Biology. 20, 5, p. 397-406 10 p.

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112 Citations (Scopus)

Micrococcal Nuclease Does Not Substantially Bias Nucleosome Mapping

Allan, J., Fraser, R. M., Owen-Hughes, T. & Keszenman-Pereyra, D., 30 Mar 2012, In : Journal of Molecular Biology. 417, 3, p. 152-164 13 p.

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51 Citations (Scopus)
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Micro-proteomics with iterative data analysis: proteome analysis in C.elegans at the single worm level

Bensaddek, D., Narayan, V., Nicolas, A., Brenes Murillo, A., Gartner, A., Kenyon, C. & Lamond, A., 10 Feb 2016, In : Proteomics. 16, 3, p. 381-392

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13 Citations (Scopus)
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Microtubule assembly by the Apc protein is regulated by importin-beta-RanGTP

Dikovskaya, D., Li, Z., Newton, I. P., Davidson, I., Hutchins, J. R. A., Kalab, P., Clarke, P. R. & Nathke, I. S., 1 Mar 2010, In : Journal of Cell Science. 123, 5, p. 736-746 11 p.

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23 Citations (Scopus)

Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE)

Deutsch, E. W., Ball, C. A., Berman, J. J., Bova, G. S., Brazma, A., Bumgarner, R. E., Campbell, D., Causton, H. C., Christiansen, J. H., Daian, F., Dauga, D., Davidson, D. R., Gimenez, G., Goo, Y. A., Grimmond, S., Henrich, T., Herrmann, B. G., Johnson, M. H., Korb, M., Mills, J. C. & 20 others, Oudes, A. J., Parkinson, H. E., Pascal, L. E., Pollet, N., Quackenbush, J., Ramialison, M., Ringwald, M., Salgado, D., Sansone, S-A., Sherlock, G., Stoeckert, C. J., Swedlow, J., Taylor, R. C., Walashek, L., Warford, A., Wilkinson, D. G., Zhou, Y., Zon, L. I., Liu, A. Y. & True, L. D., Mar 2008, In : Nature Biotechnology. 26, 3, p. 305-312 8 p.

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87 Citations (Scopus)

Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes

Platani, M., Trinkle-Mulcahy, L., Porter, M., Jeyaprakash, A. A. & Earnshaw, W. C., 6 Jul 2015, In : Journal of Cell Biology. 210, 1, p. 45-62 18 p.

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8 Citations (Scopus)

miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

Remenyi, J., van den Bosch, M. W. M., Palygin, O., Mistry, R. B., McKenzie, C., Macdonald, A., Hutvagner, G., Arthur, J. S. C., Frenguelli, B. G. & Pankratov, Y., 26 Apr 2013, In : PLoS ONE. 8, 4, 14 p., e62509.

Research output: Contribution to journalArticle

90 Citations (Scopus)

Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord

Wilcock, A. C., Swedlow, J. R. & Storey, K. G., 15 May 2007, In : Development. 134, 10, p. 1943-54 12 p.

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74 Citations (Scopus)

Modelling contact spread of infection in host-parasitoid systems: Vertical transmission of pathogens can cause chaos

Preedy, K. F., Schofield, P. G., Liu, S., Matzavinos, A., Chaplain, M. A. J. & Hubbard, S. F., 7 Feb 2010, In : Journal of Theoretical Biology. 262, 3, p. 441-451 11 p.

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4 Citations (Scopus)
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3 Citations (Scopus)
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Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications

Pearce, I. G., Chaplain, M. A. J., Schofield, P. G., Anderson, A. R. A. & Hubbard, S. F., 2006, In : Journal of Theoretical Biology. 241, 4, p. 876-886 11 p.

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26 Citations (Scopus)

Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex

Pereira, G., Tanaka, T. U., Nasmyth, K. & Schiebel, E., 2001, In : EMBO Journal. 20, 22, p. 6359-70 12 p.

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205 Citations (Scopus)

Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle

Risso, G., Pelisch, F., Pozzi, B., Mammi, P., Blaustein, M., Colman-Lerner, A. & Srebrow, A., 2013, In : Cell Cycle. 12, 19, p. 3165-3174 10 p.

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12 Citations (Scopus)

Modulation of activation-associated host cell gene expression by the apicomplexan parasite Theileria annulata

Durrani, Z., Weir, W., Pillai, S., Kinnaird, J. & Shiels, B., 2012, In : Cellular Microbiology.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Modulation of higher order chromatin conformation in mammalian cell nuclei can be mediated by polyamines and divalent cations

Visvanathan, A., Ahmed, K., Even-Faitelson, L., Lleres, D., Bazett-Jones, D. P. & Lamond, A. I., 2013, In : PLoS ONE. 8, 6, 16 p., e67689.

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36 Citations (Scopus)

Molecular analysis of the coiled body

Bohmann, K., Ferreira, J., Santama, N., Weis, K. & Lamond, A. I., 1 Jan 1995, In : Journal of Cell Science. 108, SUPPL. 19, p. 107-113 7 p.

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81 Citations (Scopus)

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

Varshney, D., Petit, A-P., Bueren-Calabuig, J. A., Jansen, C., Fletcher, D. A., Peggie, M., Weidlich, S., Scullion, P., Pisliakov, A. V. & Cowling, V. H., 1 Dec 2016, In : Nucleic Acids Research. 44, 21, p. 10423-10436 14 p.

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15 Citations (Scopus)
356 Downloads (Pure)

Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation

Hamilton, D. L., Philp, A., MacKenzie, M. G., Patton, A., Towler, M. C., Gallagher, I. J., Bodine, S. C. & Baar, K., 15 Aug 2014, In : American Journal of Physiology, Endocrinology and Metabolism. 307, 4, p. E365-E373 9 p.

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22 Citations (Scopus)
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Molecular cloning and over-expression of the glyoxylate bypass operon from Escherichia coli ML308

el-Mansi, E. M., MacKintosh, C., Duncan, K., Holms, W. H. & Nimmo, H. G., 1987, In : Biochemical Journal. 242, 3, p. 661-665 5 p.

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19 Citations (Scopus)

Molecular mechanisms facilitating the initial kinetochore encounter with spindle microtubules

Vasileva, V., Gierlinski, M., Yue, Z., O'Reilly, N., Kitamura, E. & Tanaka, T. U., 26 Apr 2017, In : Journal of Cell Biology. 216, 6, p. 1809-1822 14 p.

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7 Citations (Scopus)
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Molecular mechanisms of kinetochore capture by spindle microtubules

Tanaka, K., Mukae, N., Dewar, H., Breugel, M. V., James, E. K., Prescott, A. R., Antony, C. & Tanaka, T. U., 2005, In : Nature. 434, 7036, p. 987-994 8 p.

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205 Citations (Scopus)

Molecular mechanisms of microtubule-dependent kinetochore transport toward spindle poles

Tanaka, K., Kitamura, E., Kitamura, Y. & Tanaka, T. U., 2007, In : Journal of Cell Biology. 178, 2, p. 269-81 13 p.

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116 Citations (Scopus)

Monitoring Keap1-Nrf2 interactions in single live cells

Baird, L., Swift, S., Llères, D. & Dinkova-Kostova, A. T., 1 Nov 2014, In : Biotechnology Advances. 32, 6, p. 1133-1144 12 p.

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75 Citations (Scopus)
338 Downloads (Pure)

Morphological and genetic characterisation of the root system architecture of selected barley recombinant chromosome substitution lines using an integrated phenotyping approach

Canto, C. D. L. F., Kalogiros, D. I., Ptashnyk, M., George, T. S., Waugh, R., Bengough, A. G., Russell, J. & Dupuy, L. X., 14 Jun 2018, In : Journal of Theoretical Biology. 447, p. 84-97 14 p.

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2 Citations (Scopus)
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Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism

Maure, J-F., Kitamura, E. & Tanaka, T. U., 18 Dec 2007, In : Current Biology. 17, 24, p. 2175-2182 8 p.

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77 Citations (Scopus)

mRNA Cap methylation in pluripotency and differentiation

Grasso, L., Suska, O., Davidson, L., Gonatopoulos-Pournatzis, T., Williamson, R., Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M. P. & Cowling, V. H., 2 Aug 2016, In : Cell Reports. 16, 5, p. 1352-1365 14 p.

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12 Citations (Scopus)
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mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II-dependent transcription

Varshney, D., Lombardi, O., Schweikert, G., Dunn, S., Suska, O. & Cowling, V., May 2018, In : Cell Reports. 23, 5, p. 1530-1542 13 p.

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8 Citations (Scopus)
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Multi-batch TMT reveals false positives, batch effects and missing values

Brenes Murillo, A., Hukelmann, J., Bensaddek, D. & Lamond, A., 1 Oct 2019, In : Molecular and Cellular Proteomics. 18, 10, p. 1967-1980 14 p.

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10 Citations (Scopus)
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Multidimentional proteomics for cell biology

Larance, M. & Lamond, A. I., May 2015, In : Nature Reviews Molecular Cell Biology. 16, 5, p. 269-280 12 p.

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204 Citations (Scopus)
275 Downloads (Pure)

Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation

Wang, Y., Tatham, M. H., Schmidt-Heck, W., Swann, C., Singh-Dolt, K., Meseguer-Ripolles, J., Lucendo-Villarin, B., Kunath, T., Rudd, T. R., Smith, A. J. H., Hengstler, J. G., Godoy, P., Hay, R. T. & Hay, D. C., 28 Jun 2019, In : iScience. 16, p. 206-217 12 p.

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5 Citations (Scopus)
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Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans

Harvald, E. B., Sprenger, R. R., Dall, K. B., Ejsing, C. S., Nielsen, R., Mandrup, S., Brenes Murillo, A., Larance, M., Gartner, A., Lamond, A. & Færgeman, N. J., 26 Jul 2017, In : Cell Systems. 5, 1, p. 38-52.e4 13 p.

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10 Citations (Scopus)
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Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line

Wicky, C., Alpi, A., Passannante, M., Rose, A., Gartner, A. & Muller, F., 2004, In : Molecular and Cellular Biology. 24, 11, p. 5016-5027 12 p.

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54 Citations (Scopus)

Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-Kinase in 1321N1 astrocytoma cells

Tang, X., Batty, I. H. & Downes, C. P., Jan 2002, In : Journal of Biological Chemistry. 277, 1, p. 338-344 7 p.

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39 Citations (Scopus)

Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus

Bohmann, K., Ferreira, J. A. & Lamond, A. I., 15 Nov 1995, In : Journal of Cell Biology. 131, 4, p. 817-831 15 p.

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136 Citations (Scopus)

Mutational signatures are jointly shaped by DNA damage and repair

Volkova, N. V., Meier, B., González-Huici, V., Bertolini, S., Gonzalez, S., Vöhringer, H., Abascal, F., Martincorena, I., Campbell, P. J., Gartner, A. & Gerstung, M., 1 May 2020, In : Nature Communications. 11, p. 1-15 15 p., 2169.

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Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers

Meier, B., Volkova, N. V., Hong, Y., Schofield, P., Campbell, P. J., Gerstung, M. & Gartner, A., May 2018, In : Genome Research. 28, 5, p. 666-675 10 p.

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19 Citations (Scopus)
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Mutations in Caenorhabditis elegans neuroligin-like glit-1, the apoptosis pathway and the calcium chaperone crt-1 increase dopaminergic neurodegeneration after 6-OHDA treatment

Offenburger, S-L., Jongsma, E. & Gartner, A., 18 Jan 2018, In : PLoS Genetics. 14, 1, p. 1-34 34 p., e1007106.

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6 Citations (Scopus)
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Mutations of NFKBIA, encoding I kappa B alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases

Lake, A., Shield, L. A., Cordano, P., Chui, D. T. Y., Osborne, J., Crae, S., Wilson, K. S., Tosi, S., Knight, S. J. L., Gesk, S., Siebert, R., Hay, R. T. & Jarrett, R. F., 15 Sep 2009, In : International Journal of Cancer. 125, 6, p. 1334-1342 9 p.

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51 Citations (Scopus)

Mutations to the histone H3 alpha N region selectively alter the outcome of ATP-dependent nucleosome-remodelling reactions

Somers, J. & Owen-Hughes, T., May 2009, In : Nucleic Acids Research. 37, 8, p. 2504-2513 10 p.

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17 Citations (Scopus)
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Mutations which block the binding of calmodulin to Spc110p cause multiple mitotic defects

Stirling, D. A., Rayner, T. F., Prescott, A. R. & Stark, M. J. R., 1996, In : Journal of Cell Science. 109, p. 1297-1310 14 p.

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33 Citations (Scopus)

Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse

Mastromina, I., Verrier, L., Clara Silva, J., Storey, K. & Dale, J., 30 Jul 2018, In : Development. 145, 14, p. 1-14 14 p., dev161091.

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3 Citations (Scopus)
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MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia

Pippa, R., Dominguez, A., Malumbres, R., Endo, A., Arriazu, E., Marcotegui, N., Guruceaga, E. & Odero, M. D., 6 Jun 2016, In : Oncotarget. 8, p. 53989-54003 15 p.

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8 Citations (Scopus)
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