Gene Regulation and Expression

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Eukaryotic DNA replication reconstituted outside the cell

Blow, J. J., May 1988, In : BioEssays. 8, 5, p. 149-152 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Evaluating performance in three-dimensional fluorescence microscopy

Murray, J. M., Appleton, P. L., Swedlow, J. R. & Waters, J. C., Dec 2007, In : Journal of Microscopy. 228, 3, p. 390-405 16 p.

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85 Citations (Scopus)
248 Downloads (Pure)

Evaluating the use of HILIC in large-scale, multi dimensional proteomics: horses for courses?

Bensaddek, D., Nicolas, A. & Lamond, A. I., 30 Nov 2015, In : International Journal of Mass Spectrometry. 391, p. 105-114 10 p.

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5 Citations (Scopus)
145 Downloads (Pure)

Evaluation of the CaMAL2 promoter for regulated expression of genes in Candida albicans

Backen, A. C., Broadbent, I. D., Fetherston, R. W., Rosamond, J. D. C., Schnell, N. F. & Stark, M. J. R., 2000, In : Yeast. 16, 12, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity

Sasaki, T., Li, A., Gillespie, P. J., Blow, J. J. & Gilbert, D. M., Sep 2011, In : Nucleus. 2, 5, p. 455-464

Research output: Contribution to journalArticle

4 Citations (Scopus)

Evidence for substrate assisted catalysis in N-acetylphosphoglucosamine mutase

Raimi, O. G., Hurtado Guerrero, R. & van Aalten, D. M. F., 16 Aug 2018, In : The Biochemical journal. 475, 15, p. 2547-2557 11 p.

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Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction

Pourkarimi, E., Greiss, S. & Gartner, A., Mar 2012, In : Cell Death & Differentiation. 19, 3, p. 406-415 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

Tanaka, T. U., Rachidi, N., Janke, C., Pereira, G., Galova, M., Schiebel, E., Stark, M. J. R. & Nasmyth, K., 2002, In : Cell. 108, 3, p. 317-329 13 p.

Research output: Contribution to journalArticle

527 Citations (Scopus)

Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

Kimber, W. A., Trinkle-Mulcahy, L., Cheung, P. C. F., Deak, M., Marsden, L. J., Kieloch, A., Watt, S., Javier, R. T., Gray, A., Downes, C. P., Lucocq, J. M. & Alessi, D. R., 1 Feb 2002, In : Biochemical Journal. 361, 3, p. 525-536 12 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Evolutionary conserved regulation of HIF-1 beta by NF-kappa B

van Uden, P., Kenneth, N. S., Webster, R., Muller, H. A., Mudie, S. & Rocha, S., Jan 2011, In : PLoS Genetics. 7, 1, p. - 15 p., e1001285.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations

Schofield, P., Chaplain, M. & Hubbard, S., 2005, In : Journal of Theoretical Biology. 237, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress

Woodward, A. M., Göhler, T., Luciani, M. G., Oehlmann, M., Ge, X., Gartner, A., Jackson, D. A. & Blow, J. J., 2006, In : Journal of Cell Biology. 173, 5, p. 673-83 11 p.

Research output: Contribution to journalArticle

236 Citations (Scopus)

Exo70, a subunit of the exocyst complex, interacts with SNEVhPrp19/hPso4 and is involved in pre-mRNA splicing

Dellago, H., Löscher, M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A. I. & Grillari, J., 15 Aug 2011, In : Biochemical Journal. 438, p. 81-91 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Expanded Interactome of the Intrinsically Disordered Protein Dss1

Schenstrøm, S. M., Rebula, C. A., Tatham, M. H., Hendus-Altenburger, R., Jourdain, I., Hay, R. T., Kragelund, B. B. & Hartmann-Petersen, R., 23 Oct 2018, In : Cell Reports. 25, 4, p. 862-870 9 p.

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2 Citations (Scopus)
118 Downloads (Pure)

Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth

Huart, A-S., MacLaine, N. J., Narayan, V. & Hupp, T. R., 20 Aug 2012, In : PLoS ONE. 7, 8, e43391.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Expression of reducing sugar accumulation in interspecific somatic hybrids of potato

Craig, A. L., Morrison, I., Baird, E., Waugh, R., Coleman, M., Davie, P. & Powell, W., 1 Apr 1994, In : Plant Cell Reports. 13, 7, p. 401-405 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
51 Citations (Scopus)
27 Citations (Scopus)

Fa1p is a 171 kDa protein essential for axonemal microtubule severing in Chlamydomonas

Finst, R. J., Kim, P. J., Griffis, E. R. & Quarmby, L. M., 2000, In : Journal of Cell Science. 113, 11, p. 1963-71 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

FACT facilitates chromatin transcription by RNA polymerases I and III

Birch, J. L., Tan, B. C-M., Panov, K. I., Panova, T. B., Andersen, J. S., Owen-Hughes, T. A., Russell, J., Lee, S-C. & Zomerdijk, J. C. B. M., 8 Apr 2009, In : EMBO Journal. 28, 7, p. 854-865 12 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Family-wide analysis of poly(ADP-ribose) polymerase activity

Vyas, S., Matic, I., Uchima, L., Rood, J., Zaja, R., Hay, R. T., Ahel, I. & Chang, P., 21 Jul 2014, In : Nature Communications. 5, 13 p., 4426.

Research output: Contribution to journalArticle

Open Access
174 Citations (Scopus)

Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J., 21 Sep 2012, In : Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Farmers without borders-genetic structuring in century old barley (Hordeum vulgare)

Forsberg, N. E. G., Russell, J., Macaulay, M., Leino, M. W. & Hagenblad, J., Feb 2015, In : Heredity. 114, 2, p. 195-206

Research output: Contribution to journalArticle

13 Citations (Scopus)

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

Cole, C., Sobala, A., Lu, C., Thatcher, S. R., Bowman, A., Brown, J. W. S., Green, P. J., Barton, G. J. & Hutvagner, G., Dec 2009, In : RNA: a Publication of the RNA Society. 15, 12, p. 2147-2160 14 p.

Research output: Contribution to journalArticle

333 Citations (Scopus)

FMDV replicons encoding green fluorescent protein are replication competent

Tulloch, F., Pathania, U., Luke, G. A., Nicholson, J., Stonehouse, N. J., Rowlands, D. J., Jackson, T., Tuthill, T., Haas, J., Lamond, A. I. & Ryan, M. D., 1 Dec 2014, In : Journal of Virological Methods. 209, p. 35-40 6 p.

Research output: Contribution to journalArticle

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12 Citations (Scopus)
117 Downloads (Pure)

FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21

Yamada, K., Ono, M., Bensaddek, D., Lamond, A. I. & Rocha, S., 1 Aug 2013, In : Cell cycle (Georgetown, Tex.). 12, 15, p. 2348-2354 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation

Janke, C., Ortíz, J., Tanaka, T. U., Lechner, J. & Schiebel, E., 2002, In : EMBO Journal. 21, 1-2, p. 181-93 13 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35

Chusainow, J., Ajuh, P. M., Trinkle-Mulcahy, L., Sleeman, J. E., Ellenberg, J. & Lamond, A. I., Aug 2005, In : RNA. 11, 8, p. 1201-1214 14 p.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

FRG1P-mediated aggregation of proteins involved in pre-mRNA processing

van Koningsbruggen, S., Straasheijm, K. R., Sterrenburg, E., de Graaf, N., Dauwerse, H. G., Frants, R. R. & van der Maarel, S. M., 2007, In : Chromosoma. 116, 1, p. 53-64 12 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

From snoRNA to miRNA: Dual function regulatory non-coding RNAs

Scott, M. S. & Ono, M., 1 Nov 2011, In : Biochimie. 93, 11, p. 1987-1992 6 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

Full volume super-resolution imaging of thick mitotic spindle using 3D AO STED microscope

McGloin, D., Swedlow, J. & Zdankowski, P., 1 Apr 2019, In : Biomedical Optics Express. 10, 4, p. 1999-2009 11 p., #352466.

Research output: Contribution to journalArticle

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6 Citations (Scopus)
127 Downloads (Pure)

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

Ajuh, P., Kuster, B., Panov, K., Zomerdijk, J. C. B. M., Mann, M. & Lamond, A. I., 2000, In : EMBO Journal. 19, 23, p. 6569-6581 13 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)
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48 Downloads (Pure)

Functional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline development

Moser, S. C., von Elsner, S., Buessing, I., Alpi, A., Schnabel, R. & Gartner, A., Apr 2009, In : PLoS Genetics. 5, 4, p. - 15 p., e1000451.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Functional domains of the Xenopus replication licensing factor Cdt1

Ferenbach, A., Li, A., Brito-Martins, M. & Blow, J. J., 2005, In : Nucleic Acids Research. 33, 1, p. 316-24 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Functional interactions between ubiquitin E2 enzymes and TRIM proteins

Napolitano, L. M., Jaffray, E. G., Hay, R. T. & Meroni, G., 1 Mar 2011, In : Biochemical Journal. 434, p. 309-319 11 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star

Hsiung, F., Griffis, E. R., Pickup, A., Powers, M. A. & Moses, K., 2001, In : Mechanisms of Development. 107, 1-2, p. 13-23 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import

Hodgson, B., Li, A., Tada, S. & Blow, J. J., 2002, In : Current Biology. 12, 8, p. 678-683 6 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)
Open Access
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11 Citations (Scopus)
177 Downloads (Pure)

Gene regulation under low oxygen: holding your breath for transcription

Rocha, S., Aug 2007, In : Trends in Biochemical Sciences. 32, 8, p. 389-97 9 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Genetically separable functional elements mediate the optimal expression and stringent regulation of a bacterial tRNA gene

Lamond, A. I. & Travers, A. A., Feb 1985, In : Cell. 40, 2, p. 319-326 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

Gorelik, A., Galan Bartual, S., Borodkin, V., Varghese, J., Ferenbach, A. & van Aalten, D., Nov 2019, In : Nature Structural & Molecular Biology. 26, 11, p. 1071-1077 7 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
14 Downloads (Pure)

Germline survival and apoptosis

Gartner, A., Boag, P. R. & Blackwell, T. K., 1 Jan 2008, In : WormBook. p. 1-20 20 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Global membrane protein interactome analysis using in vivo crosslinking and MS-based protein correlation profiling

Larance, M., Kirkwood, K. J., Tinti, M., Brenes Murillo, A., Ferguson, M. & Lamond, A., 1 Jul 2016, In : Molecular & Cellular Proteomics. 15, 7, p. 2476-2490 15 p.

Research output: Contribution to journalArticle

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27 Citations (Scopus)
114 Downloads (Pure)

Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3

Larance, M., Rowland, A. F., Hoehn, K. L., Humphreys, D. T., Preiss, T., Guilhaus, M. & James, D. E., Apr 2010, In : Molecular & Cellular Proteomics. 9, 4, p. 682-694 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Global proteomics analysis of the response to starvation in C. elegans

Larance, M., Pourkarimi, E., Wang, B., Brenes Murillo, A., Kent, R., Lamond, A. I. & Gartner, A., 1 Jul 2015, In : Molecular & Cellular Proteomics. 14, 7, p. 1989-2001 13 p.

Research output: Contribution to journalArticle

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20 Citations (Scopus)
163 Downloads (Pure)

Global Reprogramming of Host SUMOylation during Influenza Virus Infection

Domingues, P., Golebiowski, F., Tatham, M. H., Lopes, A. M., Taggart, A., Hay, R. T. & Hale, B. G., 17 Nov 2015, In : Cell Reports. 13, 7, p. 1467-1480 14 p.

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24 Citations (Scopus)
143 Downloads (Pure)

Global subcellular characterization of protein degradation using quantitative proteomics

Larance, M., Ahmad, Y., Kirkwood, K. J., Ly, T. & Lamond, A. I., Mar 2013, In : Molecular & Cellular Proteomics. 12, 3, p. 638-650 13 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Glutathione transferases

Hayes, J. D., Flanagan, J. U. & Jowsey, I. R., 2005, In : Annual Review of Pharmacology and Toxicology. 45, p. 51-88 38 p.

Research output: Contribution to journalArticle

2460 Citations (Scopus)

Glycosylation Directs Targeting and Activation of Cystatin F from Intracellular and Extracellular Sources

Colbert, J. D., Plechanovova, A. & Watts, C., Apr 2009, In : Traffic. 10, 4, p. 425-437 13 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)