Gene Regulation and Expression

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A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans

González-Huici, V., Wang, B. & Gartner, A., 1 Aug 2017, In : Genetics. 206, 4, p. 1853-1864 12 p.

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3 Citations (Scopus)
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Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies

Geoffroy, M-C., Jaffray, E. G., Walker, K. J. & Hay, R. T., 1 Dec 2010, In : Molecular Biology of the Cell. 21, 23, p. 4227-4239 13 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

A Screen for Novel Phosphoinositide 3-kinase Effector Proteins

Dixon, M. J., Gray, A., Boisvert, F-M., Agacan, M., Morrice, N. A., Gourlay, R., Leslie, N. R., Downes, C. P. & Batty, I. H., Apr 2011, In : Molecular & Cellular Proteomics. 10, 4, p. - 13 p., 003178.

Research output: Contribution to journalArticle

25 Citations (Scopus)

ASF/SF2: a splice site selector

Lamond, A. I., 1991, In : Trends in Biochemical Sciences. 16, C, p. 452-453 2 p.

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2 Citations (Scopus)

Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis - Evidence that the coiled body is a kinetic nuclear structure

Carmo-Fonseca, M., Ferreira, J. & Lamond, A. I., 26 Feb 1993, In : Journal of Cell Biology. 120, 4, p. 841-852 12 p.

Research output: Contribution to journalArticle

175 Citations (Scopus)

Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits

Zomerdijk, J. C., Beckmann, H., Comai, L. & Tjian, R., 1994, In : Science. 266, 5193, p. 2015-2018 4 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)
45 Citations (Scopus)

A SUMO-Dependent Protein Network Regulates Chromosome Congression During Oocyte Meiosis

Pelisch, F., Tammsalu, T., Wang, B., Jaffray, E. G., Gartner, A. & Hay, R. T., 5 Jan 2017, In : Molecular Cell. 65, 1, p. 66-77 12 p.

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21 Citations (Scopus)
323 Downloads (Pure)

Asymmetry in the assembly of the RNAi enzyme complex

Schwarz, D. S., Hutvagner, G., Du, T., Xu, Z., Aronin, N. & Zamore, P. D., 2003, In : Cell. 115, 2, p. 199-208 10 p.

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2030 Citations (Scopus)

ATP-dependent looping of DNA by ISWI

Lia, G., Indrieri, M., Owen-Hughes, T., Finzi, L., Podesta, A., Milani, P. & Dunlap, D., Sep 2008, In : Journal of Biophotonics. 1, 4, p. 280-286 7 p.

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10 Citations (Scopus)

ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA

De Cian, A., Praly, E., Ding, F., Singh, V., Lavelle, C., Le Cam, E., Croquette, V., Pietrement, O. & Bensimon, D., 2012, In : PLoS ONE. 7, 2, p. - 13 p., e31845.

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6 Citations (Scopus)
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12 Citations (Scopus)
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Aurora B regulates MCAK at the mitotic centromere

Andrews, P. D., Ovechkina, Y., Morrice, N., Wagenbach, M., Duncan, K., Wordeman, L. & Swedlow, J. R., 2004, In : Developmental Cell. 6, 2, p. 253-268 16 p.

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396 Citations (Scopus)

Autophagosomes cooperate in the degradation of intracellular C-terminal fragments of the amyloid precursor protein via the MVB/lysosomal pathway

González, A. E., Muñoz, V. C., Cavieres, V. A., Bustamante, H. A., Cornejo, V-H., Januário, Y. C., González, I., Hetz, C., daSilva, L. L., Rojas-Fernández, A., Hay, R. T., Mardones, G. A. & Burgos, P. V., Jun 2017, In : FASEB Journal. 31, 6, p. 2446-2459 14 p.

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18 Citations (Scopus)
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A versatile partner of eukaryotic protein complexes that is involved in multiple biological processes: Kti11/Dph3

Baer, C., Zabel, R., Liu, S., Stark, M. J. R. & Schaffrath, R., Sep 2008, In : Molecular Microbiology. 69, 5, p. 1221-1233 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

Jares, P., Luciani, M. G. & Blow, J. J., 2004, In : BMC Molecular Biology. 5, p. 1-14 14 p., 5.

Research output: Contribution to journalArticle

21 Citations (Scopus)

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 others, Greb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-Puxbaum, A., Ehrenhöfer-Wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M-Y., Owen-Hughes, T., Ettmayer, P., Pearson, M., McConnell, D. B. & Ciulli, A., Jul 2019, In : Nature Chemical Biology. 15, 7, p. 672-680 9 p.

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35 Citations (Scopus)
65 Downloads (Pure)
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38 Citations (Scopus)

Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase

Jowsey, I. R., Thomson, R. E., Orton, T. C., Elcombe, C. R. & Hayes, J. D., 2003, In : Biochemical Journal. 373, Pt 2, p. 559-69 11 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Bi-orienting chromosomes on the mitotic spindle

Tanaka, T. U., 2002, In : Current Opinion in Cell Biology. 14, 3, p. 365-71 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication

Kundu, L. R., Seki, M., Watanabe, N., Murofushi, H., Furukohri, A., Waga, S., Score, A. J., Blow, J. J., Horikoshi, M., Enomoto, T. & Tada, S., Jun 2011, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 6, p. 1129-1136 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Blom7 alpha Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEVPrp19-Pso4

Grillari, J., Löscher, M., Denegri, M., Lee, K., Fortschegger, K., Eisenhaber, F., Ajuh, P., Lamond, A. I., Katinger, H. & Grillari-Voglauer, R., 16 Oct 2009, In : Journal of Biological Chemistry. 284, 42, p. 29193-29204 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Bod1, a novel kinetochore protein required for chromosome biorientation

Porter, I. M., McClelland, S. E., Khoudoli, G. A., Hunter, C. J., Andersen, J. S., McAinsh, A. D., Blow, J. J. & Swedlow, J. R., 15 Oct 2007, In : Journal of Cell Biology. 179, 2, p. 187-197 11 p.

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40 Citations (Scopus)
267 Downloads (Pure)

BOD1 Is Required for Cognitive Function in Humans and Drosophila

Esmaeeli-Nieh, S., Fenckova, M., Porter, I. M., Motazacker, M. M., Nijhof, B., Castells-Nobau, A., Asztalos, Z., Weißmann, R., Behjati, F., Tzschach, A., Felbor, U., Scherthan, H., Sayfati, S. M., Ropers, H. H., Kahrizi, K., Najmabadi, H., Swedlow, J. R., Schenck, A. & Kuss, A. W., 11 May 2016, In : PLoS Genetics. 12, 5, p. 1-22 22 p., e1006022.

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8 Citations (Scopus)
128 Downloads (Pure)

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

Porter, I., Schleicher, K., Porter, M. & Swedlow, J., 25 Oct 2013, In : Nature Communications. 4, 2677.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Body image and weight consciousness among South Asian, Italian and general population women in Britain

Bush, H. M., Williams, R. G. A., Lean, M. E. J. & Anderson, A. S., Dec 2001, In : Appetite. 37, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos

Sonneville, R., Craig, G., Labib, K., Gartner, A. & Blow, J. J., 21 Jul 2015, In : Cell Reports. 12, 3, p. 405-417 13 p.

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15 Citations (Scopus)
197 Downloads (Pure)

Both isoforms of protein phosphatase Z are essential for the maintenance of cell size and integrity in Saccharomyces cerevisiae in response to osmotic stress

Hughes, V., Müller, A., Stark, M. J. R. & Cohen, P. T. W., Aug 1993, In : European Journal of Biochemistry. 216, 1, p. 269-279 11 p.

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43 Citations (Scopus)
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6 Citations (Scopus)
178 Downloads (Pure)

BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., González-Aguilera, C., Lambert, J. P., Lee, S. B., Zhao, X., Alabert, C., Johansen, J. V., Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, A., 18 Jan 2016, In : EMBO Journal. 35, 2, p. 176-192 17 p.

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42 Citations (Scopus)

BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm

Hobley, L., Ostrowski, A., Rao, F. V., Bromley, K. M., Porter, M., Prescott, A. R., Macphee, C. E., van Aalten, D. M. F. & Stanley-Wall, N. R., 13 Aug 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. 13600-13605 6 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In : eLife. 3, p. 1-28 28 p., e02863.

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16 Citations (Scopus)
171 Downloads (Pure)

Building a scientific data grid with DIGS

Beckett, M. G., Allton, C. R., Davies, C. T. H., Davis, I., Flynn, J. M., Grant, E. J., Hamilton, R. S., Irving, A. C., Kenway, R. D., Ostrowski, R. H., Perry, J. T., Swedlow, J. R. & Trew, A., 28 Jun 2009, In : Philosophical Transactions of the Royal Society A - Mathematical Physical and Engineering Sciences. 367, 1897, p. 2471-2481 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

Ahmed, S., Alpi, A., Hengartner, M. O. & Gartner, A., Dec 2001, In : Current Biology. 11, 24, p. 1934-1944 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis

Greiss, S., Hall, J., Ahmed, S. & Gartner, A., 15 Oct 2008, In : Genes & Development. 22, 20, p. 2831-2842 12 p.

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57 Citations (Scopus)

C. elegans whole genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency.

Meier, B., Cooke, S. L., Weiss, J., Bailly, A. P., Alexandrov, L. B., Marshall, J., Raine, K., Maddison, M., Anderson, E., Stratton, M. R., Gartner, A. & Campbell, P. J., 2014, In : Genome Research. 24, p. 1624-1636 14 p.

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82 Citations (Scopus)
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1 Citation (Scopus)
206 Downloads (Pure)

Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing

Jantsch, V., Tang, L., Pasierbek, P., Penkner, A., Nayak, S., Baudrimont, A., Schedl, T., Gartner, A. & Loidl, J., Dec 2007, In : Molecular Biology of the Cell. 18, 12, p. 4911-4920 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cajal body dynamics and association with chromatin are ATP-dependent

Platani, M., Goldberg, I., Lamond, A. I. & Swedlow, J. R., Feb 2002, In : Nature Cell Biology. 4, 7, p. 502-508 7 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo

Sleeman, J. E., Trinkle-Mulcahy, L., Prescott, A. R., Ogg, S. C. & Lamond, A. I., 1 Apr 2003, In : Journal of Cell Science. 116, 10, p. 2039-2050 12 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP

Fogarty, S., Hawley, S. A., Green, K. A., Saner, N., Mustard, K. J. & Hardie, D. G., 15 Feb 2010, In : Biochemical Journal. 426, p. 109-118 10 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes

Yip, M. F., Ramm, G., Larance, M., Hoehn, K. L., Wagner, M. C., Guilhaus, M. & James, D. E., 5 Nov 2008, In : Cell Metabolism. 8, 5, p. 384-398 15 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

CAPAM: the mRNA cap adenosine N6 methyltransferase

Cowling, V., 1 Mar 2019, In : Trends in Biochemical Sciences. 44, 3, p. 183-185 3 p., 1545.

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5 Citations (Scopus)
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CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures

Galloway, A., Atrih, A., Grzela, R., Darzynkiewicz, E., Ferguson, M. A. J. & Cowling, V. H., 26 Feb 2020, In : Open Biology. 10, 2, p. 1-13 13 p., 190306.

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1 Citation (Scopus)
40 Downloads (Pure)

Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes

McCarthy, D. J., Rostom, R., Huang, Y., Kunz, D. J., Danecek, P., Bonder, M. J., Hagai, T., Lyu, R., Wang, W., Gaffney, D. J., Simons, B. D., Stegle, O. & Teichmann, S. A., 16 Mar 2020, In : Nature Methods. 17, 4, p. 414-421 8 p.

Research output: Contribution to journalArticle

Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription

Panova, T. B., Panov, K. I., Russell, J. & Zomerdijk, J. C. B. M., 2006, In : Molecular and Cellular Biology. 26, 16, p. 5957-5968 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

Pravata, V., Muha, V., Gundogdu, M., Ferenbach, A., Kakade, P., Vandadi, V., Wilmes, A. C., Borodkin, V., Joss, S., Stavridis, M. & van Aalten, D., 23 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 30, p. 14961-14970 10 p.

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6 Citations (Scopus)
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Catalytic RNA and the origin of genetic systems

Lamond, A. I. & Gibson, T. J., 1990, In : Trends in Genetics. 6, C, p. 145-149 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

Franz, A., Orth, M., Pirson, P. A., Sonneville, R., Blow, J. J., Gartner, A., Stemmann, O. & Hoppe, T., 7 Oct 2011, In : Molecular Cell. 44, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription

Aregger, M., Kaskar, A., Varshney, D., Fernandez-Sanchez, M. E., Inesta-Vaquera, F. A., Weidlich, S. & Cowling, V. H., 3 Mar 2016, In : Molecular Cell. 61, 5, p. 734-746 13 p.

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20 Citations (Scopus)
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