Gene Regulation and Expression

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2006

Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures

Dürr, H., Flaus, A., Owen-Hughes, T. & Hopfner, K-P., 2006, In : Nucleic Acids Research. 34, 15, p. 4160-7 8 p.

Research output: Contribution to journalArticle

Open Access
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75 Citations (Scopus)
180 Downloads (Pure)

SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes

Fujii, M., Lyakh, L. A., Bracken, C. P., Fukuoka, J., Hayakawa, M., Tsukiyama, T., Soll, S. J., Harris, M., Rocha, S., Roche, K. C., Tominaga, S., Jen, J., Perkins, N. D., Lechleider, R. J. & Roberts, A. B., 8 Dec 2006, In : Molecular Cell. 24, 5, p. 771-83 13 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

SUMO protease SENP1 induces isomerization of the scissile peptide bond

Shen, L., Tatham, M. H., Dong, C., Zagorska, A., Naismith, J. H. & Hay, R. T., Dec 2006, In : Nature Structural & Molecular Biology. 13, 12, p. 1069-1077 9 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

The DNA repair helicases XPD and FancJ have essential iron-sulfur domains

Rudolf, J., Makrantoni, V., Ingledew, W. J., Stark, M. J. R. & White, M. F., 15 Sep 2006, In : Molecular Cell. 23, 6, p. 801-8 8 p.

Research output: Contribution to journalArticle

235 Citations (Scopus)

The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin

Hastie, C. J., Vázquez-Martin, C., Philp, A., Stark, M. J. R. & Cohen, P. T. W., Jul 2006, In : FEBS Journal. 273, 14, p. 3322-34 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology

MacRae, J. I., Obado, S. O., Turnock, D. C., Roper, J. R., Kierans, M., Kelly, J. M. & Ferguson, M. A. J., May 2006, In : Molecular and Biochemical Parasitology. 147, 1, p. 126-136 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

UBF activates RNA polymerase I transcription by stimulating promoter escape

Panov, K. I., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M., 2006, In : The EMBO Journal. 25, 14, p. 3310-3322 13 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

UV-induced fragmentation of Cajal bodies

Cioce, M., Boulon, S., Matera, A. G. & Lamond, A. I., 6 Nov 2006, In : Journal of Cell Biology. 175, 3, p. 401-413 13 p.

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Open Access
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57 Citations (Scopus)
326 Downloads (Pure)
2005

ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases

Rocha, S. & Perkins, N. D., Jun 2005, In : Cell Cycle. 4, 6, p. 756-9 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

A robust and selective method for the quantification of glycosylphosphatidylinositols in biological samples

MacRae, J. I. & Ferguson, M. A. J., Feb 2005, In : Glycobiology. 15, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

Li, A. & Blow, J. J., Jan 2005, In : The EMBO Journal. 24, 2, p. 395-404 10 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Characterization of hCINAP, a novel coilin-interacting protein by a transcript from the transcription factor TAFIID32 locus

Santama, N., Ogg, S. C., Malekkou, A., Zographos, S. E., Weis, K. & Lamond, A. I., 28 Oct 2005, In : Journal of Biological Chemistry. 280, 43, p. 36429-36441 13 p.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

Larance, M., Ramm, G., Stöckli, J., van Dam, E. M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J. R., Guilhaus, M. & James, D. E., 11 Nov 2005, In : Journal of Biological Chemistry. 280, 45, p. 37803-37813 11 p.

Research output: Contribution to journalArticle

292 Citations (Scopus)

Chromosome bi-orientation on the mitotic spindle

Tanaka, T. U., 2005, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 360, 1455, p. 581-9 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Condensed mitotic chromatin is accessible to transcription factors and chromatin structural protiens

Chen, D., Dundr, M., Wang, C., Leung, A., Lamond, A., Misteli, T. & Huang, S., Jan 2005, In : Journal of Cell Biology. 168, 1, p. 41-54 14 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations

Schofield, P., Chaplain, M. & Hubbard, S., 2005, In : Journal of Theoretical Biology. 237, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35

Chusainow, J., Ajuh, P. M., Trinkle-Mulcahy, L., Sleeman, J. E., Ellenberg, J. & Lamond, A. I., Aug 2005, In : RNA. 11, 8, p. 1201-1214 14 p.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

Functional domains of the Xenopus replication licensing factor Cdt1

Ferenbach, A., Li, A., Brito-Martins, M. & Blow, J. J., 2005, In : Nucleic Acids Research. 33, 1, p. 316-24 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Glutathione transferases

Hayes, J. D., Flanagan, J. U. & Jowsey, I. R., 2005, In : Annual Review of Pharmacology and Toxicology. 45, p. 51-88 38 p.

Research output: Contribution to journalArticle

2460 Citations (Scopus)

Interaction of U-box E3 ligase SNEV with PSMB4, the β7 subunit of the 20 S proteasome

Löscher, M., Fortschegger, K., Ritter, G., Wostry, M., Voglauer, R., Schmid, J. A., Watters, S., Rivett, A. J., Ajuh, P. M., Lamond, A. I., Katinger, H. & Grillari, J., 1 Jun 2005, In : Biochemical Journal. 388, 2, p. 593-603 11 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Kinetochore capture and bi-orientation on the mitotic spindle

Tanaka, T. U., Stark, M. J. R. & Tanaka, K., 2005, In : Nature Reviews Molecular Cell Biology. 6, 12, p. 929-42 14 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Mannosyl-diinositolphospho-ceramide, the major yeast plasma membrane sphingolipid, governs toxicity of Kluyveromyces lactis zymocin

Zink, S., Mehlgarten, C., Kitamoto, H. K., Nagase, J., Jablonowski, D., Dickson, R. C., Stark, M. J. R. & Schaffrath, R., May 2005, In : Eukaryotic Cell. 4, 5, p. 879-89 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Molecular mechanisms of kinetochore capture by spindle microtubules

Tanaka, K., Mukae, N., Dewar, H., Breugel, M. V., James, E. K., Prescott, A. R., Antony, C. & Tanaka, T. U., 2005, In : Nature. 434, 7036, p. 987-994 8 p.

Research output: Contribution to journalArticle

204 Citations (Scopus)

Nucleolar proteome dynamics

Andersen, J. S., Lam, Y. W., Leung, A. K. L., Ong, S. E., Lyon, C. E., Lamond, A. I. & Mann, M., 6 Jan 2005, In : Nature. 433, 7021, p. 77-83 7 p.

Research output: Contribution to journalArticle

840 Citations (Scopus)

p53 isoforms can regulate p53 transcriptional activity

Bourdon, J. C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K. & Lane, D. P., 15 Sep 2005, In : Genes & Development. 19, 18, p. 2122-2137 16 p.

Research output: Contribution to journalArticle

558 Citations (Scopus)

P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner

Fox, A. H., Bond, C. S. & Lamond, A. I., 1 Nov 2005, In : Molecular Biology of the Cell. 16, 11, p. 5304-5315 12 p.

Research output: Contribution to journalArticle

143 Citations (Scopus)

Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions

Pendle, A. F., Clark, G. P., Boon, R., Lewandowska, D., Lam, Y. W., Andersen, J., Mann, M., Lamond, A. I., Brown, J. W. S. & Shaw, P. J., 2005, In : Molecular Biology of the Cell. 16, 1, p. 260-269 10 p.

Research output: Contribution to journalArticle

278 Citations (Scopus)

Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

Rocha, S., Garrett, M. D., Campbell, K. J., Schumm, K. & Perkins, N. D., Mar 2005, In : EMBO Journal. 24, 6, p. 1157-1169 13 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

RNA-polymerase-I-directed rDNA transcription, life and works

Russell, J. & Zomerdijk, J. C. B. M., 2005, In : Trends in Biochemical Sciences. 30, 2, p. 87-96 10 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly

Grillari, J., Ajuh, P., Stadler, G., Löscher, M., Voglauer, R., Ernst, W., Chusainow, J., Eisenhaber, F., Pokar, M., Fortschegger, K., Grey, M., Lamond, A. I. & Katinger, H., 1 Nov 2005, In : Nucleic Acids Research. 33, 21, p. 6868-6883 16 p.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)

Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1

Shen, L., Liu, H., Dong, C., Xirodimas, D., Naismith, J. H. & Hay, R. T., Apr 2005, In : The EMBO Journal. 24, 7, p. 1341-1351 11 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes

MacRae, J. I., Acosta-Serrano, A., Morrice, N. A., Mehlert, A. & Ferguson, M. A. J., 1 Apr 2005, In : Journal of Biological Chemistry. 280, 13, p. 12201-12211 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor

Blair, D. E., Schuettelkopf, A. W., MacRae, J. I., van Aalten, D. M. F. & Thornton, J. (ed.), 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 43, p. 15429-15434 6 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter

Friedrich, J. K., Panov, K. I., Cabart, P., Russell, J. & Zomerdijk, J. C. B. M., 2005, In : Journal of Biological Chemistry. 280, 33, p. 29551-29558 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

The chromosome cycle: coordinating replication and segregation

Blow, J. J. & Tanaka, T. U., 2005, In : EMBO Reports. 6, 11, p. 1028-34 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

Bates, G. J., Nicol, S. M., Wilson, B. J., Jacobs, A-M. F., Bourdon, J-C., Wardrop, J., Gregory, D. J., Lane, D. P., Perkins, N. D. & Fuller-Pace, F. V., 9 Feb 2005, In : The EMBO Journal. 24, 3, p. 543-553 11 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)

The nucleolus

Lam, Y. W., Trinkle-Mulcahy, L. & Lamond, A. I., 2005, In : Journal of Cell Science. 118, 7, p. 1335-1337 3 p.

Research output: Contribution to journalArticle

Open Access
137 Citations (Scopus)

The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging

Goldberg, I. G., Allan, C., Burel, J-M., Creager, D., Falconi, A., Hochheiser, H., Johnston, J., Mellen, J., Sorger, P. K. & Swedlow, J. R., 2005, In : Genome Biology. 6, 5, R47.

Research output: Contribution to journalArticle

151 Citations (Scopus)

The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcription

Nieduszynski, C. A., Blow, J. J. & Donaldson, A. D., 2005, In : Nucleic Acids Research. 33, 8, p. 2410-20 11 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number

Roper, J. R., Guther, M. L. S., MacRae, J. I., Prescott, A. R., Hallyburton, I., Acosta-Serrano, A. & Ferguson, M. A. J., 20 May 2005, In : Journal of Biological Chemistry. 280, 20, p. 19728-19736 9 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

Schumacher, B., Hanazawa, M., Lee, M-H., Nayak, S., Volkmann, K., Hofmann, R., Hengartner, M., Schedl, T. & Gartner, A., Feb 2005, In : Cell. 120, 3, p. 357-368 12 p.

Research output: Contribution to journalArticle

156 Citations (Scopus)

Two-dimensional liquid chromatography/tandem mass spectrometry analysis of Gradiflow fractionated native human plasma

Wasinger, V. C., Locke, V. L., Raftery, M. J., Larance, M., Rothemund, D., Liew, A., Bate, I. & Guilhaus, M., Aug 2005, In : Proteomics. 5, 13, p. 3397-3401 5 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection

Tatham, M. H., Kim, S., Jaffray, E., Song, J., Chen, Y. & Hay, R. T., Jan 2005, In : Nature Structural & Molecular Biology. 12, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)
2004

3D3/lyric: A novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus

Sutherland, H. G. E., Lam, Y. W., Briers, S., Lamond, A. I. & Bickmore, W. A., 10 Mar 2004, In : Experimental Cell Research. 294, 1, p. 94-105 12 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Active repression of antiapoptotic gene expression by RelA(p65) NF-kB

Campbell, K. J., Rocha, S. & Perkins, N. D., Mar 2004, In : Molecular Cell. 13, 6, p. 853-865 13 p.

Research output: Contribution to journalArticle

331 Citations (Scopus)

A proteomic study of SUMO-2 target proteins

Vertegaal, A. C. O., Ogg, S. C., Jaffray, E., Rodriguez, M. S., Hay, R. T., Andersen, J. S., Mann, M. & Lamond, A. I., 6 Aug 2004, In : Journal of Biological Chemistry. 279, 32, p. 33791-33798 8 p.

Research output: Contribution to journalArticle

Open Access
176 Citations (Scopus)

Aurora B regulates MCAK at the mitotic centromere

Andrews, P. D., Ovechkina, Y., Morrice, N., Wagenbach, M., Duncan, K., Wordeman, L. & Swedlow, J. R., 2004, In : Developmental Cell. 6, 2, p. 253-268 16 p.

Research output: Contribution to journalArticle

396 Citations (Scopus)

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

Jares, P., Luciani, M. G. & Blow, J. J., 2004, In : BMC Molecular Biology. 5, p. 1-14 14 p., 5.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus

Luciani, M. G., Oehlmann, M. & Blow, J. J., 1 Dec 2004, In : Journal of Cell Science. 117, 25, p. 6019-30 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility

Griffis, E. R., Craige, B., Dimaano, C., Ullman, K. S. & Powers, M. A., 2004, In : Molecular Biology of the Cell. 15, 4, p. 1991-2002 12 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)