Gene Regulation and Expression

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2002

A microRNA in a multiple-turnover RNAi enzyme complex

Hutvagner, G. & Zamore, P. D., 2002, In : Science. 297, 5589, p. 2056-2060 5 p.

Research output: Contribution to journalArticle

1499 Citations (Scopus)

A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing

Ajuh, P., Chusainow, J., Ryder, U. & Lamond, A. I., 1 Dec 2002, In : EMBO Journal. 21, 23, p. 6590-6602 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Bi-orienting chromosomes on the mitotic spindle

Tanaka, T. U., 2002, In : Current Opinion in Cell Biology. 14, 3, p. 365-71 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Cajal body dynamics and association with chromatin are ATP-dependent

Platani, M., Goldberg, I., Lamond, A. I. & Swedlow, J. R., Feb 2002, In : Nature Cell Biology. 4, 7, p. 502-508 7 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Cell type-specific responses of human cells to inhibition of replication licensing

Shreeram, S., Sparks, A., Lane, D. P. & Blow, J. J., 2002, In : Oncogene. 21, 43, p. 6624-6632 9 p.

Research output: Contribution to journalArticle

139 Citations (Scopus)

Directed proteomic analysis of the human nucleolus

Andersen, J. S., Lyon, C. E., Fox, A. H., Leung, A. K. L., Lam, Y. W., Steen, H., Mann, M. & Lamond, A. I., Jan 2002, In : Current Biology. 12, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

756 Citations (Scopus)

Essential functions of Sds22p in chromosome stability and nuclear localization of PP1

Peggie, M., MacKelvie, S., Bloecher, A., Knatko, E., Tatchell, K. & Stark, M., 2002, In : Journal of Cell Science. 115, 1, p. 195-206 12 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

Tanaka, T. U., Rachidi, N., Janke, C., Pereira, G., Galova, M., Schiebel, E., Stark, M. J. R. & Nasmyth, K., 2002, In : Cell. 108, 3, p. 317-329 13 p.

Research output: Contribution to journalArticle

527 Citations (Scopus)

Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

Kimber, W. A., Trinkle-Mulcahy, L., Cheung, P. C. F., Deak, M., Marsden, L. J., Kieloch, A., Watt, S., Javier, R. T., Gray, A., Downes, C. P., Lucocq, J. M. & Alessi, D. R., 1 Feb 2002, In : Biochemical Journal. 361, 3, p. 525-536 12 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation

Janke, C., Ortíz, J., Tanaka, T. U., Lechner, J. & Schiebel, E., 2002, In : EMBO Journal. 21, 1-2, p. 181-93 13 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import

Hodgson, B., Li, A., Tada, S. & Blow, J. J., 2002, In : Current Biology. 12, 8, p. 678-683 6 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Inhibition of autophagy in mitotic animal cells

Eskelinen, E-L., Prescott, A. R., Cooper, J., Brachmann, S. M., Wang, L., Tang, X., Backer, J. M. & Lucocq, J. M., 2002, In : Traffic. 3, 12, p. 878-893 16 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)
Open Access
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43 Citations (Scopus)
676 Downloads (Pure)

Large-scale isolation of Cajal bodies from HeLa cells

Lam, Y. W., Lyon, C. E. & Lamond, A. I., Jul 2002, In : Molecular Biology of the Cell. 13, 7, p. 2461-2473 13 p.

Research output: Contribution to journalArticle

Open Access
64 Citations (Scopus)

Mammalian nuclei become licensed for DNA replication during late telophase

Dimitrova, D. S., Prokhorova, T. A., Blow, J. J., Todorov, I. T. & Gilbert, D. M., 2002, In : Journal of Cell Science. 115, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)
15 Citations (Scopus)

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, J. R., Hu, K., Andrews, P. D., Roos, D. S. & Murray, J. M., 19 Feb 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2014-2019 6 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-Kinase in 1321N1 astrocytoma cells

Tang, X., Batty, I. H. & Downes, C. P., Jan 2002, In : Journal of Biological Chemistry. 277, 1, p. 338-344 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry

Walsh, E. P., Lamont, D. J., Beattie, K. A. & Stark, M. J. R., 2002, In : Biochemistry. 41, 7, p. 2409-2420 12 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Nuclear processes controlled by molecular machines

Fox, A. H. & Lamond, A. I., 23 May 2002, In : Genome Biology. 3, 6, p. 4016.1-4016.3 3 p., 4016.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Nup98 is a mobile nucleoporin with transcription-dependent dynamics

Griffis, E. R., Altan, N., Lippincott-Schwartz, J. & Powers, M. A., 2002, In : Molecular Biology of the Cell. 13, 4, p. 1282-97 16 p.

Research output: Contribution to journalArticle

184 Citations (Scopus)

P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2

Xirodimas, D. P., Chisholm, J., Desterro, J. M. S., Lane, D. P., Hay, R. T. & Celis, J. (ed.), 2002, In : FEBS Letters. 528, 1-3, p. 207-211 5 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Paraspeckles: a novel nuclear domain

Fox, A. H., Lam, Y. W., Leung, A. K. L., Lyon, C. E., Andersen, J., Mann, M. & Lamond, A. I., Jan 2002, In : Current Biology. 12, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

317 Citations (Scopus)

Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity

Fichtner, L., Frohloff, F., Jablonowski, D., Stark, M. J. R. & Schaffrath, R., Aug 2002, In : Molecular Microbiology. 45, 3, p. 817-26 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Replication licensing - origin licensing: defining the proliferative state?

Blow, J. J. & Hodgson, B., 2002, In : Trends in Cell Biology. 12, 2, p. 72-78 7 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)

Splicing regulation at the second catalytic step by Sex-lethal involves 3′ splice site recognition by SPF45

Lallena, M. J., Chalmers, K. J., Llamazares, S., Lamond, A. I. & Valcárcel, J., 3 May 2002, In : Cell. 109, 3, p. 285-296 12 p.

Research output: Contribution to journalArticle

Open Access
109 Citations (Scopus)

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells

Moore, W. J., Zhang, C. & Clarke, P. R., Aug 2002, In : Current Biology. 12, 16, p. 1442-1447 6 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98

Hodel, A. E., Hodel, M. R., Griffis, E. R., Hennig, K. A., Ratner, G. A., Xu, S. & Powers, M. A., 2002, In : Molecular Cell. 10, 2, p. 347-58 12 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Yeast Pescadillo is required for multiple activities during 60s ribosomal subunit synthesis

Oeffinger, M., Lueng, A., Lamond, A. & Tollervey, D., 21 May 2002, In : RNA. 8, 5, p. 626-636 11 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2001

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

Hutvagner, G., McLachlan, J., Pasquinelli, A. E., Balint, E., Tuschl, T. & Zamore, P. D., 2001, In : Science. 293, 5531, p. 834-838 5 p.

Research output: Contribution to journalArticle

1951 Citations (Scopus)

A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing

Ajuh, P., Sleeman, J., Chusainow, J. & Lamond, A. I., 2001, In : Journal of Biological Chemistry. 276, 45, p. 42370-42381 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

A role for the adenomatous Polyposis Coli protein in chromosome segregation

Kaplan, K. B., Burds, A. A., Swedlow, J. R., Bekir, S. S., Sorger, P. K. & Näthke, I. S., 2001, In : Nature Cell Biology. 3, 4, p. 429-432 4 p.

Research output: Contribution to journalArticle

445 Citations (Scopus)
45 Citations (Scopus)

Body image and weight consciousness among South Asian, Italian and general population women in Britain

Bush, H. M., Williams, R. G. A., Lean, M. E. J. & Anderson, A. S., Dec 2001, In : Appetite. 37, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

Ahmed, S., Alpi, A., Hengartner, M. O. & Gartner, A., Dec 2001, In : Current Biology. 11, 24, p. 1934-1944 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Chromatin-associated Protein Phosphatase I Regulates Aurora-B and Histone H3 Phosphorylation

Murnion, M. E., Adams, R. R., Callister, D. M., Allis, C. D., Earnshaw, W. C. & Swedlow, J. R., 13 Jul 2001, In : Journal of Biological Chemistry. 276, 28, p. 26656-26665 10 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)

Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53

Xirodimas, D., Stephen, C. W. & Lane, D., Oct 2001, In : Experimental Cell Research. 270, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Control of chromosomal DNA replication in the early Xenopus embryo

Blow, J. J., 2001, In : EMBO Journal. 20, 13, p. 3293-3297 5 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo

Xirodimas, D., Saville, M. K., Edling, C., Lane, D. & Lain, S., 2001, In : Oncogene. 20, 36, p. 4972-4983 12 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)

DNA replication: stable driving prevents fatal smashes

Donaldson, A. D. & Blow, J. J., 2001, In : Current Biology. 11, 23, p. R979-R982 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells

Trinkle-Mulcahy, L., Sleeman, J. E. & Lamond, A. I., 27 Dec 2001, In : Journal of Cell Science. 114, 23, p. 4219-4228 10 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star

Hsiung, F., Griffis, E. R., Pickup, A., Powers, M. A. & Moses, K., 2001, In : Mechanisms of Development. 107, 1-2, p. 13-23 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters

Miller, G., Panov, K. I., Friedrich, J. K., Trinkle-Mulcahy, L., Lamond, A. I. & Zomerdijk, J. C. B. M., Mar 2001, In : The EMBO Journal. 20, 6, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

133 Citations (Scopus)

Kluyveromyces lactis zymocin mode of action is linked to RNA polymerase II function via Elongator

Jablonowski, D., Frohloff, F., Fichtner, L., Stark, M. J. R. & Schaffrath, R., Nov 2001, In : Molecular Microbiology. 42, 4, p. 1095-105 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex

Pereira, G., Tanaka, T. U., Nasmyth, K. & Schiebel, E., 2001, In : EMBO Journal. 20, 22, p. 6359-70 12 p.

Research output: Contribution to journalArticle

204 Citations (Scopus)
104 Citations (Scopus)

Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times

Blow, J. J., Gillespie, P. J., Francis, D. & Jackson, D. A., 2001, In : Journal of Cell Biology. 152, 1, p. 15-25 11 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

Tada, S., Li, A., Maiorano, D., Mechali, M. & Blow, J. J., 2001, In : Nature Cell Biology. 3, 2, p. 107-113 7 p.

Research output: Contribution to journalArticle

381 Citations (Scopus)

Saccharomyces cerevisiae cell wall chitin, the Kluyveromyces lactis zymocin receptor

Jablonowski, D., Fichtner, L., Martin, V. J., Klassen, R., Meinhardt, F., Stark, M. J. R. & Schaffrath, R., Oct 2001, In : Yeast. 18, 14, p. 1285-99 15 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)