Gene Regulation and Expression

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Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus

Lyon, C. E., Bohmann, K., Sleeman, J. & Lamond, A. I., 10 Jan 1997, In : Experimental Cell Research. 230, 1, p. 84-93 10 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Spatial organization of large-scale chromatin domains in the nucleus: A magnified view of single chromosome territories

Ferreira, J., Paolella, G., Ramos, C. & Lamond, A. I., 29 Dec 1997, In : Journal of Cell Biology. 139, 7, p. 1597-1610 14 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)
1996

Analysis of intra-specific somatic hybrids of potato (Solanum tuberosum) using simple sequence repeats

Provan, J., Kumar, A., Shepherd, L., Powell, W. & Waugh, R., Dec 1996, In : Plant Cell Reports. 16, 3-4, p. 196-199 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

Weis, K., Dingwall, C. & Lamond, A. I., 16 Dec 1996, In : EMBO Journal. 15, 24, p. 7120-7128 9 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

Cis-acting elements distinct from the 5' splice site promote U1- independent pre-mRNA splicing

Crispino, J. D., Mermoud, J. E., Lamond, A. I. & Sharp, P. A., 19 Nov 1996, In : RNA. 2, 7, p. 664-673 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Mutations which block the binding of calmodulin to Spc110p cause multiple mitotic defects

Stirling, D. A., Rayner, T. F., Prescott, A. R. & Stark, M. J. R., 1996, In : Journal of Cell Science. 109, p. 1297-1310 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

RNA splicing: Unexpected spliceosome diversity

Kreivi, J. P. & Lamond, A. I., 1 Jan 1996, In : Current Biology. 6, 7, p. 802-805 4 p.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)

The conserved amino-terminal domain of hSRP1α is essential for nuclear protein import

Weis, K., Ryder, U. & Lamond, A. I., 15 Apr 1996, In : EMBO Journal. 15, 8, p. 1818-1825 8 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)

The dynamics of coiled bodies in the nucleus of adenovirus-infected cells

Rebelo, L., Almeida, F., Ramos, C., Bohmann, K., Lamond, A. I. & Carmo-Fonseca, M., 1 Jul 1996, In : Molecular Biology of the Cell. 7, 7, p. 1137-1151 15 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
16 Citations (Scopus)
1995

A regulated MET3-GLC7 gene fusion provides evidence of a mitotic role for Saccharomyces cerevisiae protein phosphatase 1.

Black, S., Andrews, P. D., Sneddon, A. A. & Stark, M. J. R., 30 Jun 1995, In : Yeast. 11, 8, p. 747-759 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Dynamic organization of splicing factors in adenovirus-infected cells

Bridge, E., Xia, D. X., Carmo-Fonseca, M., Cardinali, B., Lamond, A. I. & Pettersson, U., 1 Jan 1995, In : Journal of Virology. 69, 1, p. 281-290 10 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Identification of hnRNP P2 as TLS/FUS using electrospray mass spectrometry

Calvio, C., Neubauer, G., Mann, M. & Lamond, A. I., Sep 1995, In : RNA. 1, 7, p. 724-733 10 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Identification of hSRP1α as a functional receptor for nuclear localization sequences

Weis, K., Mattaj, I. W. & Lamond, A. I., 19 May 1995, In : Science. 268, 5213, p. 1049-1053 5 p.

Research output: Contribution to journalArticle

300 Citations (Scopus)

Influenza virus NS1 protein alters the subnuclear localization of cellular splicing components

Fortes, P., Lamond, A. I. & Ortin, J., 1 Apr 1995, In : Journal of General Virology. 76, 4, p. 1001-1007 7 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Molecular analysis of the coiled body

Bohmann, K., Ferreira, J., Santama, N., Weis, K. & Lamond, A. I., 1 Jan 1995, In : Journal of Cell Science. 108, SUPPL. 19, p. 107-113 7 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus

Bohmann, K., Ferreira, J. A. & Lamond, A. I., 15 Nov 1995, In : Journal of Cell Biology. 131, 4, p. 817-831 15 p.

Research output: Contribution to journalArticle

Open Access
136 Citations (Scopus)

RNA Processing: Wilms' tumour - the splicing connection?

Lamond, A. I., Aug 1995, In : Current Biology. 5, 8, p. 862-865 4 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase

MACKELVIE, SARAH. H., ANDREWS, PAUL. D. & STARK, MICHAEL. J. R., Jul 1995, In : Molecular and Cellular Biology. 15, 7, p. 3777-3785 9 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)
1994

Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits

Zomerdijk, J. C., Beckmann, H., Comai, L. & Tjian, R., 1994, In : Science. 266, 5193, p. 2015-2018 4 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Characterization of the S-adenosylmethionine decarboxylase (SAMDC) gene of potato

Arif, S. A. M., Taylor, M. A., George, L. A., Butler, A. R., Burch, L. R., Davies, H. V., Stark, M. J. R. & Kumar, A., Oct 1994, In : Plant Molecular Biology. 26, 1, p. 327-338 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei

Ferreira, J. A., Carmo-Fonseca, M. & Lamond, A. I., 1 Jul 1994, In : Journal of Cell Biology. 126, 1, p. 11-23 13 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Expression of reducing sugar accumulation in interspecific somatic hybrids of potato

Craig, A. L., Morrison, I., Baird, E., Waugh, R., Coleman, M., Davie, P. & Powell, W., 1 Apr 1994, In : Plant Cell Reports. 13, 7, p. 401-405 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inositol trisphosphate metabolism in Saccharomyces cerevisiae - identification, purification and properties of Inositol 1,4,5-trisphosphae 6-kinase

ESTEVEZ, F., PULFORD, D., STARK, M. J. R., CARTER, A. N. & Downes, C. P., 15 Sep 1994, In : Biochemical Journal. 302, p. 709-716 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Interaction with calmodulin is required for the function of Spc110p, an essential component of the yeast spindle pole body

Stirling, D. A., Welch, K. A. & Stark, M. J. R., 1994, In : EMBO Journal. 13, 18, p. 4329-4342 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel solid-phase synthesis of branched oligoribonucleotides, including a substrate for the RNA debranching enzyme

Sproat, B. S., Beijer, B., Grøtli, M., Ryder, U., Morand, K. L. & Lamond, A. I., 1 Dec 1994, In : Journal of the Chemical Society, Perkin Transactions 1. 4, p. 419-431 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract

Cardinali, B., Cohen, P. T. W. & Lamond, A. I., 3 Oct 1994, In : FEBS Letters. 352, 3, p. 276-280 5 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits

Comai, L. ., Zomerdijk, J. C., Beckmann, H., Zhou, S., Admon, A. & Tjian, R., 1994, In : Science. 266, 5193, p. 1966-1972 7 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism

Mermoud, J. E., Cohen, P. T. W. & Lamond, A. I., 1 Dec 1994, In : EMBO Journal. 13, 23, p. 5679-5688 10 p.

Research output: Contribution to journalArticle

257 Citations (Scopus)

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

Weis, K., Rambaud, S., Lavau, C., Jansen, J., Carvalho, T., Carmo-Fonseca, M., Lamond, A. & Dejean, A., 28 Jan 1994, In : Cell. 76, 2, p. 345-356 12 p.

Research output: Contribution to journalArticle

604 Citations (Scopus)
76 Citations (Scopus)

The linear-plasmid-encoded toxin produced by the yeast Pichia acaciae : characterization and comparison with the toxin of Kluyveromyces lactis

McCracken, D. A., Martin, V. J., Stark, M. J. R. & Bolen, P. L., Feb 1994, In : Microbiology. 140, p. 425-431 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Two Saccharomyces cerevisiae genes which control sensitivity to G1 arrest induced by Kluyveromyces lactis toxin

BUTLER, ANDREW. R., WHITE, JOHN. H., FOLAWIYO, YETUNDE., EDLIN, ANGELA., GARDINER, DONALD. & STARK, MICHAEL. J. R., Sep 1994, In : Molecular and Cellular Biology. 14, 9, p. 6306-6316 11 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)
1993
7 Citations (Scopus)

A glimpse into the spliceosome

Lamond, A. I., Jan 1993, In : Current Biology. 3, 1, p. 62-64 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A herpes simplex virus type 1 immediate-early gene product, IE63, regulates small nuclear ribonucleoprotein distribution

Phelan, A., Carmo-Fonseca, M., Mclauchlan, J., Lamond, A. I. & Clements, J. B., 1 Oct 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 19, p. 9056-9060 5 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis - Evidence that the coiled body is a kinetic nuclear structure

Carmo-Fonseca, M., Ferreira, J. & Lamond, A. I., 26 Feb 1993, In : Journal of Cell Biology. 120, 4, p. 841-852 12 p.

Research output: Contribution to journalArticle

175 Citations (Scopus)

Both isoforms of protein phosphatase Z are essential for the maintenance of cell size and integrity in Saccharomyces cerevisiae in response to osmotic stress

Hughes, V., Müller, A., Stark, M. J. R. & Cohen, P. T. W., Aug 1993, In : European Journal of Biochemistry. 216, 1, p. 269-279 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Interaction of the human autoantigen p150 with splicing snRNPs

Blencowe, B. J., Carmo-Fonseca, M., Behrens, S. E., Luhrmann, R. & Lamond, A. I., 1 Jul 1993, In : Journal of Cell Science. 105, 3, p. 685-697 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Localisation of splicing snRNPs in mammalian cells

Lamond, A. I. & Carmo-Fonseca, M., 1 Aug 1993, In : Molecular Biology Reports. 18, 2, p. 127-133 7 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Nuclear organization of splicing small nuclear ribonucleoproteins in adenovirus-infected cells

Bridge, E., Carmo-Fonseca, M., Lamond, A. & Pettersson, U., 1 Oct 1993, In : Journal of Virology. 67, 10, p. 5792-5802 11 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Nuclear organization of splicing snRNPs during differentiation of murine erythroleukemia cells in vitro

Antoniou, M., Carmo-Fonseca, M., Ferreira, J. & Lamond, A. I., 1 Dec 1993, In : Journal of Cell Biology. 123, 5, p. 1055-1068 14 p.

Research output: Contribution to journalArticle

Open Access
45 Citations (Scopus)

Secretion of β-lactamase from K. lactis using pEPS1, a convenient episomal vector designed for the secretion of foreign proteins

Macreadie, I. G., Castelli, L. A., Ward, A. C., Stark, M. J. R. & Azad, A. A., Mar 1993, In : Biotechnology Letters. 15, 3, p. 213-218 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The coiled body

Lamond, A. I. & Carmo-Fonseca, M., Jun 1993, In : Trends in Cell Biology. 3, 6, p. 198-203 6 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)
1992

Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing

Barabino, S. M. L., Sproat, B. S. & Lamond, A. I., 11 Sep 1992, In : Nucleic Acids Research. 20, 17, p. 4457-4464 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A ribosomal RNA gene promoter at the telomere of a mini-chromosome in Trypanosoma brucei

Zomerdijk, J. C. B. M., Kieft, R. & Borst, P., 1992, In : Nucleic Acids Research. 20, 11, p. 2725-2734 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit

Zhang, M., Zamore, P. D., Carmo-Fonseca, M., Lamond, A. I. & Green, M. R., 15 Sep 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 18, p. 8769-8773 5 p.

Research output: Contribution to journalArticle

Open Access
161 Citations (Scopus)