Gene Regulation and Expression

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1992

Kluyveromyces lactis killer system: ORF1 of pGKL2 has no function in immunity expression and is dispensable for killer plasmid replication and maintenance

Schaffrath, R., Stark, M. J. R., Gunge, N. & Meinhardt, F., Apr 1992, In : Current Genetics. 21, 4-5, p. 357-363 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Nuclease resistant ribozymes with high catalytic activity

Paolella, G., Sproat, B. S. & Lamond, A. I., 1 May 1992, In : EMBO Journal. 11, 5, p. 1913-1919 7 p.

Research output: Contribution to journalArticle

140 Citations (Scopus)

Protein A-calmodulin fusions: a novel approach for investigating calmodulin function in yeast

Stirling, D. A., Petrie, A., Pulford, D. J., Paterson, D. T. W. & Stark, M. J. R., 1992, In : Molecular Microbiology. 6, 6, p. 703-713 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Ser/thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

Mermoud, J. E., Cohen, P. & Lamond, A. I., 25 Oct 1992, In : Nucleic Acids Research. 20, 20, p. 5263-5269 7 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)

The regulation of chromosome replication

Blow, J. J., Jun 1992, In : Journal of Pathology. 167, 2, p. 175-179 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The use of field emission in-lens scanning electron microscopy to study the steps of assembly of the nuclear envelope in vitro

Goldberg, M. W., Blow, J. J. & Allen, T. D., May 1992, In : Journal of Structural Biology. 108, 3, p. 257-268 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

Carmo-Fonseca, M., Pepperkok, R., Carvalho, M. T. & Lamond, A. I., 1 Apr 1992, In : Journal of Cell Biology. 117, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

332 Citations (Scopus)
1991

2'-O-alkyloligoribonucleotides: Synthesis and applications in studying rna splicing

Sproat, B. S., Iribarren, A., Beijer, B., Pieles, U. & Lamond, A. I., 1991, In : Nucleosides and Nucleotides. 10, 1-3, p. 25-36 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

2'-O-alkyloligoribonucleotides, synthesis and applications in molecular biology.

Sproat, B. S., Lamond, A. I., Garcia, R. G., Beijer, B., Pieles, U., Douglas, M., Bohmann, K., Carmo-Fonseco, M., Weston, S. & O'Loughlin, S., 1991, In : Nucleic acids symposium series. 24, p. 59-62 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Alfalfa heat shock genes are differentially expressed during somatic embryogenesis

Györgyey, J., Gartner, A., Németh, K., Magyar, Z., Hirt, H., Heberle-Bors, E. & Dudits, D., 1 Jun 1991, In : Plant Molecular Biology. 16, 6, p. 999-1007 9 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)
91 Citations (Scopus)

Analysis of the response of Saccharomyces cerevisiae cells to Kluyveromyces lactis toxin

Butler, A. R., White, J. H. & Stark, M. J. R., 1 Jul 1991, In : Journal of General Microbiology. 137, 7, p. 1749-1757 9 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features

Zomerdijk, J. C. B. M., Kieft, R., Duyndam, M., Shiels, P. G. & Borst, P., 1991, In : Nucleic Acids Research. 19, 7, p. 1359-1368 10 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts

Lamm, G. M., Blencowe, B. J., Sparoat, B. S., Iribarren, A. M., Ryder, U. & Lamond, A. I., 25 Jun 1991, In : Nucleic Acids Research. 19, 12, p. 3193-3198 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

ASF/SF2: a splice site selector

Lamond, A. I., 1991, In : Trends in Biochemical Sciences. 16, C, p. 452-453 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cell cycle control of DNA replication by p34cdc2

Blow, J. J., Aug 1991, In : Seminars in Cell & Developmental Biology. 2, 4, p. 243-250 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei

Zomerdijk, J. C. B. M., Kieft, R. & Borst, P., 1991, In : Nature. 353, 6346, p. 772-775 4 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)
52 Citations (Scopus)

In vivo detection of snRNP-rich organelles in the nuclei of mammalian cells

Carmo-Fonseca, M., Pepperkok, R., Sproat, B. S., Ansorge, W., Swanson, M. S. & Lamond, A. I., 5 Jul 1991, In : EMBO Journal. 10, 7, p. 1863-1873 11 p.

Research output: Contribution to journalArticle

110 Citations (Scopus)

Kluyveromyces lactis toxin has an essential chitinase activity

BUTLER, A. R., O'DONNELL, R. W., MARTIN, V. J., GOODAY, G. W. & STARK, M. J. R., 15 Jul 1991, In : European Journal of Biochemistry. 199, 2, p. 483-488 6 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery

Carmo-Fonseca, M., Tollervey, D., Pepperkok, R., Barabino, S. M. L., Merdes, A., Brunner, C., Zamore, P. D., Green, M. R., Hurt, E. & Lamond, A. I., 1 Jan 1991, In : EMBO Journal. 10, 1, p. 195-206 12 p.

Research output: Contribution to journalArticle

176 Citations (Scopus)

Nuclear RNA processing

Lamond, A. I., Jun 1991, In : Current Opinion in Cell Biology. 3, 3, p. 493-501 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates

Norbury, C., Blow, J. & Nurse, P., Nov 1991, In : EMBO Journal. 10, 11, p. 3321-9 9 p.

Research output: Contribution to journalArticle

375 Citations (Scopus)

Site-directed ribose methylation identifies 2′-OH groups in polyadenylation substrates critical for AAUAAA recognition and poly(A) addition

Bardwell, V. J., Wickens, M., Bienroth, S., Keller, W., Sproat, B. S. & Lamond, A. I., 5 Apr 1991, In : Cell. 65, 1, p. 125-133 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
1990

2'-O-alkyl oligoribonucleotides as antisense probes

Iribarren, A. M., Sproat, B. S., Neuner, P., Sulston, I., Ryder, U. & Lamond, A. I., 1 Oct 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 19, p. 7747-7751 5 p.

Research output: Contribution to journalArticle

Open Access
100 Citations (Scopus)

2′-O-alkyl oligoribonucleotides as antisense probes

Iribarren, A. M., Sproat, B. S., Neuner, P., Sulston, I., Ryder, U. & Lamond, A. I., 1 Dec 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 19, p. 7752-7756 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

Blow, J. J. & Nurse, P., 7 Sep 1990, In : Cell. 62, 5, p. 855-862 8 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Catalytic RNA and the origin of genetic systems

Lamond, A. I. & Gibson, T. J., 1990, In : Trends in Genetics. 6, C, p. 145-149 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Components involved in nuclear pre-mRNA splicing

Krämer, A., Utans, U., Keller, W. & Lamond, A., Jun 1990, In : Molecular Biology Reports. 14, 2-3, p. 199-200 2 p.

Research output: Contribution to journalArticle

Control of surface antigen genes in African trypanosomes

Borst, P., Gommersampt, J. H., Lutgerink, J., Ouellette, M., Ten Asbroek, A. L. M. A. & Zomerdijk, J. C. B. M., 1990, In : Biochemical Society Transactions. 18, 5, p. 741-742 2 p.

Research output: Contribution to journalArticle

Metabolic complexity in the RNA world and implications for the origin of protein synthesis

Gibson, T. J. & Lamond, A. I., 1 Jan 1990, In : Journal of Molecular Evolution. 30, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Replication of purified DNA in Xenopus egg extract is dependent on nuclear assembly

Blow, J. J. & Sleeman, A. M., Mar 1990, In : Journal of Cell Science. 95 , 3, p. 383-391 9 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes

Sneddon, A. A., Cohen, P. T. W. & Stark, M. J. R., Dec 1990, In : EMBO Journal. 9, 13, p. 4339-4346 8 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Sequence-specific affinity selection of mammalian splicing complexes

Ryder, U., Sproat, B. S. & Lamond, A. I., 1 Dec 1990, In : Nucleic Acids Research. 18, 24, p. 7373-7379 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Studying pre-mRNA splicing using antisense 2-OMe RNA oligonucleotides

Lamond, A. I., Barabino, S., Blencowe, B. J., Sproat, B. & Ryder, U., Jun 1990, In : Molecular Biology Reports. 14, 2-3, 1 p., 201.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis and applications of oligoribonucleotides with selected 2′-o-methylation using the 2′-o-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting group

Beijer, B., Sulston, I., Sproat, B. S., Rider, P., Lamond, A. I. & Neuner, P., 11 Sep 1990, In : Nucleic Acids Research. 18, 17, p. 5143-5151 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly

Barabino, S. M. L., Blencowe, B. J., Ryder, U., Sproat, B. S. & Lamond, A. I., 19 Oct 1990, In : Cell. 63, 2, p. 293-302 10 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei

Zomerdijk, J. C. B. M., Ouellette, M., ten Asbroek, A. L. M. A., Kieft, R., Bommer, A. M. M., Clayton, C. E. & Borst, P., 1990, In : EMBO Journal. 9, 9, p. 2791-2801 11 p.

Research output: Contribution to journalArticle

The trimethylguanosine cap is a nuclear targeting signal for snRNPs

Lamond, A. I., Dec 1990, In : Trends in Biochemical Sciences. 15, 12, p. 451-452 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1989

Antisense probing of the human U4 U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides

Blencowe, B. J., Sproat, B. S., Ryder, U., Barabino, S. & Lamond, A. I., 3 Nov 1989, In : Cell. 59, 3, p. 531-539 9 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)
78 Citations (Scopus)

DNA replication and its control

Blow, J. J., Apr 1989, In : Current Opinion in Cell Biology. 1, 2, p. 263-267 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases

Sproat, B. S., Lamond, A. I., Beijer, B., Neuner, P. & Ryder, U., 11 May 1989, In : Nucleic Acids Research. 17, 9, p. 3373-3386 14 p.

Research output: Contribution to journalArticle

202 Citations (Scopus)

Kluyveromyces lactis toxin does not inhibit yeast adenylyl cyclase

White, J. H., Butler, A. R. & Stark, M. J. R., 19 Oct 1989, In : Nature. 341, 6243, p. 666-668 3 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Mapping U2 snRNP-pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA

Barabino, S. M. L., Sproat, B. S., Ryder, U., Blencowe, B. J. & Lamond, A. I., 1 Dec 1989, In : EMBO Journal. 8, 13, p. 4171-4178 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Nuclear structure and the control of DNA replication in the Xenopus embryo

Blow, J. J., Sheehan, M. A., Watson, J. V. & Laskey, R. A., 1989, In : Journal of Cell Science. Supplement. 12, p. 183-195 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Probing the structure and function of U2 snRNP with antisense oligonucleotides made of 2′-OMe RNA

Lamond, A. I., Sproat, B., Ryder, U. & Hamm, J., 28 Jul 1989, In : Cell. 58, 2, p. 383-390 8 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Remarkable similarities between yeast and mammalian protein phosphatases

Cohen, P., Schelling, D. L. & Stark, M. J. R., 3 Jul 1989, In : FEBS Letters. 250, 2, p. 601-606 6 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

Mills, A. D., Blow, J. J., White, J. G., Amos, W. B., Wilcock, D. & Laskey, R. A., Nov 1989, In : Journal of Cell Science. 94 , 3, p. 471-477 7 p.

Research output: Contribution to journalArticle

145 Citations (Scopus)

S phase of the cell cycle

Laskey, R. A., Fairman, M. P. & Blow, J. J., 3 Nov 1989, In : Science. 246, 4930, p. 609-614 6 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)