Gene Regulation and Expression

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2000

Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth

Andrews, P. D. & Stark, M. J. R., 2000, In : Journal of Cell Science. 113, 15, p. 2685-2693 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Editorial overview

Blow, J. J., 2000, In : Current Opinion in Cell Biology. 12, 6, p. 655-657 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evaluation of the CaMAL2 promoter for regulated expression of genes in Candida albicans

Backen, A. C., Broadbent, I. D., Fetherston, R. W., Rosamond, J. D. C., Schnell, N. F. & Stark, M. J. R., 2000, In : Yeast. 16, 12, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Fa1p is a 171 kDa protein essential for axonemal microtubule severing in Chlamydomonas

Finst, R. J., Kim, P. J., Griffis, E. R. & Quarmby, L. M., 2000, In : Journal of Cell Science. 113, 11, p. 1963-71 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

Ajuh, P., Kuster, B., Panov, K., Zomerdijk, J. C. B. M., Mann, M. & Lamond, A. I., 2000, In : EMBO Journal. 19, 23, p. 6569-6581 13 p.

Research output: Contribution to journalArticle

150 Citations (Scopus)

Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex

Romanowski, P., Marr, J., Madine, M. A., Rowles, A., Blow, J. J., Gautier, J. & Laskey, R. A., 2000, In : Journal of Biological Chemistry. 275, 6, p. 4239-4243 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

In vivo analysis of Cajal body movement, separation, and joining in live human cells

Platani, M., Goldberg, I., Swedlow, J. R. & Lamond, A. I., 31 Dec 2000, In : Journal of Cell Biology. 151, 7, p. 1561-1574 14 p.

Research output: Contribution to journalArticle

Open Access
196 Citations (Scopus)
36 Citations (Scopus)

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

Zhou, X. Z., Kops, O., Werner, A., Lu, P-J., Shen, M., Stoller, G., Kullertz, G., Stark, M., Fischer, G. & Lu, K. P., 2000, In : Molecular Cell. 6, 4, p. 873-883 11 p.

Research output: Contribution to journalArticle

448 Citations (Scopus)

Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity

Prokhorova, T. A. & Blow, J. J., 2000, In : Journal of Biological Chemistry. 275, 4, p. 2491-2498 8 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?

Jares, P., Donaldson, A. & Blow, J. J., 2000, In : EMBO Reports. 1, 4, p. 319-322 4 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

The manganese cation disrupts membrane dynamics along the secretory pathway

Towler, M. C., Prescott, A. R., James, J., Lucocq, J. M. & Ponnambalam, S., 25 Aug 2000, In : Experimental Cell Research. 259, 1, p. 167-179 13 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

The nucleolus

Lyon, C. E. & Lamond, A. I., 1 May 2000, In : Current biology : CB. 10, 9, p. R323 1 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins

Sun, W., Hola, M., Pedley, K., Tada, S., Blow, J. J., Todorov, I. T., Kearsey, S. E. & Brooks, R. F., 2000, In : Journal of Cell Science. 113 , 4, p. 683-695 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
67 Citations (Scopus)

Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading

Jares, P. & Blow, J. J., 2000, In : Genes & Development. 14, 12, p. 1528-1540 13 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)
2001

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

Hutvagner, G., McLachlan, J., Pasquinelli, A. E., Balint, E., Tuschl, T. & Zamore, P. D., 2001, In : Science. 293, 5531, p. 834-838 5 p.

Research output: Contribution to journalArticle

1967 Citations (Scopus)

A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing

Ajuh, P., Sleeman, J., Chusainow, J. & Lamond, A. I., 2001, In : Journal of Biological Chemistry. 276, 45, p. 42370-42381 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

A role for the adenomatous Polyposis Coli protein in chromosome segregation

Kaplan, K. B., Burds, A. A., Swedlow, J. R., Bekir, S. S., Sorger, P. K. & Näthke, I. S., 2001, In : Nature Cell Biology. 3, 4, p. 429-432 4 p.

Research output: Contribution to journalArticle

445 Citations (Scopus)
45 Citations (Scopus)

Body image and weight consciousness among South Asian, Italian and general population women in Britain

Bush, H. M., Williams, R. G. A., Lean, M. E. J. & Anderson, A. S., Dec 2001, In : Appetite. 37, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

Ahmed, S., Alpi, A., Hengartner, M. O. & Gartner, A., Dec 2001, In : Current Biology. 11, 24, p. 1934-1944 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Chromatin-associated Protein Phosphatase I Regulates Aurora-B and Histone H3 Phosphorylation

Murnion, M. E., Adams, R. R., Callister, D. M., Allis, C. D., Earnshaw, W. C. & Swedlow, J. R., 13 Jul 2001, In : Journal of Biological Chemistry. 276, 28, p. 26656-26665 10 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)

Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53

Xirodimas, D., Stephen, C. W. & Lane, D., Oct 2001, In : Experimental Cell Research. 270, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Control of chromosomal DNA replication in the early Xenopus embryo

Blow, J. J., 2001, In : EMBO Journal. 20, 13, p. 3293-3297 5 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo

Xirodimas, D., Saville, M. K., Edling, C., Lane, D. & Lain, S., 2001, In : Oncogene. 20, 36, p. 4972-4983 12 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)

DNA replication: stable driving prevents fatal smashes

Donaldson, A. D. & Blow, J. J., 2001, In : Current Biology. 11, 23, p. R979-R982 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells

Trinkle-Mulcahy, L., Sleeman, J. E. & Lamond, A. I., 27 Dec 2001, In : Journal of Cell Science. 114, 23, p. 4219-4228 10 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star

Hsiung, F., Griffis, E. R., Pickup, A., Powers, M. A. & Moses, K., 2001, In : Mechanisms of Development. 107, 1-2, p. 13-23 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters

Miller, G., Panov, K. I., Friedrich, J. K., Trinkle-Mulcahy, L., Lamond, A. I. & Zomerdijk, J. C. B. M., Mar 2001, In : The EMBO Journal. 20, 6, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

133 Citations (Scopus)

Kluyveromyces lactis zymocin mode of action is linked to RNA polymerase II function via Elongator

Jablonowski, D., Frohloff, F., Fichtner, L., Stark, M. J. R. & Schaffrath, R., Nov 2001, In : Molecular Microbiology. 42, 4, p. 1095-105 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex

Pereira, G., Tanaka, T. U., Nasmyth, K. & Schiebel, E., 2001, In : EMBO Journal. 20, 22, p. 6359-70 12 p.

Research output: Contribution to journalArticle

208 Citations (Scopus)
105 Citations (Scopus)

Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times

Blow, J. J., Gillespie, P. J., Francis, D. & Jackson, D. A., 2001, In : Journal of Cell Biology. 152, 1, p. 15-25 11 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

Tada, S., Li, A., Maiorano, D., Mechali, M. & Blow, J. J., 2001, In : Nature Cell Biology. 3, 2, p. 107-113 7 p.

Research output: Contribution to journalArticle

383 Citations (Scopus)

Saccharomyces cerevisiae cell wall chitin, the Kluyveromyces lactis zymocin receptor

Jablonowski, D., Fichtner, L., Martin, V. J., Klassen, R., Meinhardt, F., Stark, M. J. R. & Schaffrath, R., Oct 2001, In : Yeast. 18, 14, p. 1285-99 15 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Sit4p protein phosphatase is required for sensitivity of Saccharomyces cerevisiae to Kluyveromyces lactis zymocin

Jablonowski, D., Butler, A. R., Fichtner, L., Gardiner, D., Schaffrath, R. & Stark, M. J. R., Dec 2001, In : Genetics. 159, 4, p. 1479-1489 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN

Sleeman, J. E., Ajuh, P. & Lamond, A. I., 1 Dec 2001, In : Journal of Cell Science. 114, 24, p. 4407-4419 13 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

Schumacher, B., Hofmann, K., Boulton, S. & Gartner, A., Oct 2001, In : Current Biology. 11, 21, p. 1722-1727 6 p.

Research output: Contribution to journalArticle

254 Citations (Scopus)

The human oesophageal squamous epithelium exhibits a novel type of heat shock protein response

Yagui-Beltran, A., Craig, A. L., Lawrie, L., Thompson, D., Pospisilova, S., Johnston, D., Kernohan, N., Hopwood, D., Dillon, J. F. & Hupp, T. R., Oct 2001, In : European Journal of Biochemistry. 268, 20, p. 5343-5355 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The Induction of Cyclooxygenase-2 mRNA in Macrophages Is Biphasic and Requires both CCAAT Enhancer-binding protein β (C/EBPβ) and C/EBPδ Transcription Factors

Caivano, M., Gorgoni, B., Cohen, P. & Poli, V., 28 Dec 2001, In : Journal of Biological Chemistry. 276, 52, p. 48693-48701 9 p.

Research output: Contribution to journalArticle

Open Access
134 Citations (Scopus)

The origin of CDK regulation

Li, A. & Blow, J. J., 2001, In : Nature Cell Biology. 3, 8, p. E182-E184 3 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages

Vosper, H., Patel, L., Graham, T. L., Khoudoli, G. A., Hill, A., Macphee, C. H., Pinto, I., Smith, S. A., Suckling, K. E., Wolf, C. R. & Palmer, C. N. A., Nov 2001, In : Journal of Biological Chemistry. 276, 47, p. 44258-44265 8 p.

Research output: Contribution to journalArticle

221 Citations (Scopus)

The Saccharomyces cerevisiae phosphotyrosyl phosphatase activator proteins are required for a subset of the functions disrupted by protein phosphatase 2A mutations

Van Hoof, C., Janssens, V., De Baere, I., Stark, M. J. R., de Winde, J. H., Winderickx, J., Thevelein, J. M., Merlevede, W. & Goris, J., 2001, In : Experimental Cell Research. 264, 2, p. 372-387 16 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Use of peptides from p21 (Waf1/Cip1) to investigate PCNA function in Xenopus egg extracts

Mattock, H., Jares, P., Zheleva, D. I., Lane, D. P., Warbrick, E. & Blow, J. J., 2001, In : Experimental Cell Research. 265, 2, p. 242-251 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
15 Citations (Scopus)
2002

A microRNA in a multiple-turnover RNAi enzyme complex

Hutvagner, G. & Zamore, P. D., 2002, In : Science. 297, 5589, p. 2056-2060 5 p.

Research output: Contribution to journalArticle

1520 Citations (Scopus)

A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing

Ajuh, P., Chusainow, J., Ryder, U. & Lamond, A. I., 1 Dec 2002, In : EMBO Journal. 21, 23, p. 6590-6602 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Bi-orienting chromosomes on the mitotic spindle

Tanaka, T. U., 2002, In : Current Opinion in Cell Biology. 14, 3, p. 365-71 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)