Gene Regulation and Expression

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50 Citations (Scopus)

Cell cycle: a new check on issuing the licence

Blow, J. J. & Tada, S., 2000, In : Nature. 404, 6778, p. 560-561 2 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cell cycle control of DNA replication by p34cdc2

Blow, J. J., Aug 1991, In : Seminars in Cell & Developmental Biology. 2, 4, p. 243-250 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cell cycle progression in response to oxygen levels

Ortmann, B., Druker, J. & Rocha, S., Sep 2014, In : Cellular and Molecular Life Sciences. 71, 18, p. 3569-3582 14 p.

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34 Citations (Scopus)

Cell cycle progression requires the CDC-48(UFD-1/NPL-4) complex for efficient DNA replication

Mouysset, J., Deichsel, A., Moser, S., Hoege, C., Hyman, A. A., Gartner, A. & Hoppe, T., 2 Sep 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12879-12884 6 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Cell cycle RNA regulons coordinating early lymphocyte development

Galloway, A. & Turner, M., 2017, In : Wiley Interdisciplinary Reviews: RNA. 8, 5, p. 1-15 15 p., e1419.

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5 Citations (Scopus)
130 Downloads (Pure)

Cell fate decisions are specified by the dynamic ERK interactome

von Kriegsheim, A., Baiocchi, D., Birtwistle, M., Sumpton, D., Bienvenut, W., Morrice, N., Yamada, K., Lamond, A., Kalna, G., Orton, R., Gilbert, D. & Kolch, W., Dec 2009, In : Nature Cell Biology. 11, 12, p. 1458-1464 7 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)

Cell-Nonautonomous Regulation of C. elegans Germ Cell Death by kri-1

Ito, S., Greiss, S., Gartner, A. & Derry, W. B., 23 Feb 2010, In : Current Biology. 20, 4, p. 333-338 6 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Cell type-specific responses of human cells to inhibition of replication licensing

Shreeram, S., Sparks, A., Lane, D. P. & Blow, J. J., 2002, In : Oncogene. 21, 43, p. 6624-6632 9 p.

Research output: Contribution to journalArticle

139 Citations (Scopus)

CENP-A confers a reduction in height on octameric nucleosomes

Miell, M. D. D., Barysz, H. M., Rappsilber, J., Allshire, R. C., Fuller, C. J., Straight, A. F., Guse, A., Downes, A. & Owen-Hughes, T., 2013, In : Nature Structural & Molecular Biology.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner

Bremm, A., Moniz, S., Mader, J., Rocha, S. & Komander, D., 1 Dec 2014, In : EMBO Reports. 15, 12, p. 1268-1277 10 p.

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43 Citations (Scopus)
66 Downloads (Pure)

Cezanne regulates E2F1-dependent HIF2α expression

Moniz, S., Bandarra, D., Biddlestone, J., Campbell, K. J., Komander, D., Bremm, A. & Rocha, S., 15 Aug 2015, In : Journal of Cell Science. 128, 16, p. 3082-3093 12 p., JOCES/2015/168864.

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31 Citations (Scopus)
132 Downloads (Pure)

Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins

Rowles, A., Tada, S. & Blow, J. J., 1999, In : Journal of Cell Science. 112 , 12, p. 2011-2018 8 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Characterisation of the biflavonoid hinokiflavone as a premRNA splicing modulator that inhibits SENP

Pawellek, A., Ryder, U., Tammsalu, T., King, L. J., Kreinin, H., Ly, T., Hay, R. T., Hartley, R. & Lamond, A., 8 Sep 2017, In : eLife. 6, e27402.

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8 Citations (Scopus)
149 Downloads (Pure)

Characterization and prediction of protein nucleolar localization sequences

Scott, M. S., Boisvert, F-M., McDowall, M. D., Lamond, A. I. & Barton, G. J., Nov 2010, In : Nucleic Acids Research. 38, 21, p. 7388-7399 12 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Characterization of a new SUMO-1 nuclear body (SNB) enriched in pCREB, CBP, c-Jun in neuron-like UR61 cells

Navascues, J., Bengoechea, R., Tapia, O., Vaqué, J. P., Lafarga, M. & Berciano, M. T., 2007, In : Chromosoma. 116, 5, p. 441-451 11 p.

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11 Citations (Scopus)

Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus

Luciani, M. G., Oehlmann, M. & Blow, J. J., 1 Dec 2004, In : Journal of Cell Science. 117, 25, p. 6019-30 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Characterization of hCINAP, a novel coilin-interacting protein by a transcript from the transcription factor TAFIID32 locus

Santama, N., Ogg, S. C., Malekkou, A., Zographos, S. E., Weis, K. & Lamond, A. I., 28 Oct 2005, In : Journal of Biological Chemistry. 280, 43, p. 36429-36441 13 p.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway

Larance, M., Kirkwood, K. J., Xirodimas, D. P., Lundberg, E., Uhlen, M. & Lamond, A. I., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3

Research output: Contribution to journalArticle

17 Citations (Scopus)

Characterization of Native Protein Complexes and Protein Isoform Variation Using Size-fractionation-based Quantitative Proteomics

Kirkwood, K. J., Ahmad, Y., Larance, M. & Lamond, A. I., 1 Dec 2013, In : Molecular & Cellular Proteomics. 12, 12, p. 3851-3873 23 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Characterization of SENP7, a SUMO-2/3-specific isopeptidase

Shen, L. N., Geoffroy, M-C., Jaffray, E. G. & Hay, R. T., 15 Jul 2009, In : Biochemical Journal. 421, p. 223-230 8 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities

Weis, K., Dingwall, C. & Lamond, A. I., 16 Dec 1996, In : EMBO Journal. 15, 24, p. 7120-7128 9 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

Larance, M., Ramm, G., Stöckli, J., van Dam, E. M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J. R., Guilhaus, M. & James, D. E., 11 Nov 2005, In : Journal of Biological Chemistry. 280, 45, p. 37803-37813 11 p.

Research output: Contribution to journalArticle

293 Citations (Scopus)

Characterization of the S-adenosylmethionine decarboxylase (SAMDC) gene of potato

Arif, S. A. M., Taylor, M. A., George, L. A., Butler, A. R., Burch, L. R., Davies, H. V., Stark, M. J. R. & Kumar, A., Oct 1994, In : Plant Molecular Biology. 26, 1, p. 327-338 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

Ge, X. Q. & Blow, J. J., 27 Dec 2010, In : Journal of Cell Biology. 191, 7, p. 1285-1297 13 p.

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128 Citations (Scopus)
152 Downloads (Pure)

Chromatin and oxygen sensing in the context of JmjC histone demethylases

Shmakova, A., Batie, M., Druker, J. & Rocha, S., 15 Sep 2014, In : Biochemical Journal. 462, 3, p. 385-395 11 p.

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45 Citations (Scopus)
158 Downloads (Pure)

Chromatin-associated Protein Phosphatase I Regulates Aurora-B and Histone H3 Phosphorylation

Murnion, M. E., Adams, R. R., Callister, D. M., Allis, C. D., Earnshaw, W. C. & Swedlow, J. R., 13 Jul 2001, In : Journal of Biological Chemistry. 276, 28, p. 26656-26665 10 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)

Chromosome bi-orientation on the mitotic spindle

Tanaka, T. U., 2005, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 360, 1455, p. 581-9 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Chromosome replication in cell-free systems from Xenopus eggs

Blow, J. J., Dilworth, S. M., Dingwall, C., Mills, A. D. & Laskey, R. A., 15 Dec 1987, In : Philosophical Transactions of the Royal Society B - Biological Sciences. 317, 1187, p. 483-494 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, C. S., Bartek, J. & Gorgoulis, V. G., Jul 2016, In : Nature Cell Biology. 18, 7, p. 777-789 13 p.

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104 Citations (Scopus)
576 Downloads (Pure)

Chtop (Chromatin target of Prmt1) auto-regulates its expression level via intron retention and nonsense-mediated decay of its own mRNA

Izumikawa, K., Yoshikawa, H., Ishikawa, H., Nobe, Y., Yamauchi, Y., Philipsen, S., Simpson, R. J., Isobe, T. & Takahashi, N., Nov 2016, In : Nucleic Acids Research. 44, 20, p. 9847-9859 13 p.

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8 Citations (Scopus)
315 Downloads (Pure)

Cis-acting elements distinct from the 5' splice site promote U1- independent pre-mRNA splicing

Crispino, J. D., Mermoud, J. E., Lamond, A. I. & Sharp, P. A., 19 Nov 1996, In : RNA. 2, 7, p. 664-673 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation

Campbell, K. J., Witty, J. M., Rocha, S. & Perkins, N. D., Jan 2006, In : Cancer Research. 66, 2, p. 929-935 7 p.

Research output: Contribution to journalArticle

Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS

Hodge, K., Ten Have, S., Hutton, L. & Lamond, A. I., 2 Aug 2013, In : Journal of Proteomics. 88, p. 92-103 12 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Clinical proteomics stretch goals: EuPA 2012 roundtable report

O'Neil, S. E., Palviainen, M. J., Ten Have, S., Filiou, M., Gonzalez, A., Hodge, K., Surinova, S., Penque, D. & Baker, M. S., 2 Aug 2013, In : Journal of Proteomics. 88, p. 37-40 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
78 Citations (Scopus)

Cloning and characterization of hSRP1γ, a tissue-specific nuclear transport factor

Nachury, M. V., Ryder, U. W., Lamond, A. I. & Weis, K., 20 Jan 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 2, p. 582-587 6 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit

Zhang, M., Zamore, P. D., Carmo-Fonseca, M., Lamond, A. I. & Green, M. R., 15 Sep 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 18, p. 8769-8773 5 p.

Research output: Contribution to journalArticle

Open Access
161 Citations (Scopus)

Clusters, factories and domains: The complex structure of S-phase comes into focus

Gillespie, P. J. & Blow, J., 15 Aug 2010, In : Cell Cycle. 9, 16, p. 3218-3226 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

Dunn, S., Lombardi, O. & Cowling, V., 20 Jan 2017, In : Biochemical Journal. 474, 3, p. 377-384 8 p.

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3 Citations (Scopus)
160 Downloads (Pure)

c-Myc deregulation induces mRNA capping enzyme dependency

Lombardi, O., Varshney, D., Phillips, N. M. & Cowling, V. H., 16 Oct 2016, In : Oncotarget. 7, 50, p. 82273-82288 16 p.

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7 Citations (Scopus)
150 Downloads (Pure)

Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore

Bock, L. J., Pagliuca, C., Alfieri, C., Golfieri, C., Dal Maschio, M., De Wulf, P., Kobayashi, N., Oku, Y., Tanaka, T. U., Grove, R. A., Shrestha, K., Hazbun, T. R., Oldani, A. & Bermejo, R., 2012, In : Nature Cell Biology. 14, 6, p. 614-624 11 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53

Xirodimas, D., Stephen, C. W. & Lane, D., Oct 2001, In : Experimental Cell Research. 270, 1, p. 66-77 12 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5′-3′ exoribonuclease) in the nucleoplasm

Sato, S., Ishikawa, H., Yoshikawa, H., Izumikawa, K., Simpson, R. J. & Takahashi, N., 2 Dec 2015, In : Nucleic Acids Research. 43, 21, p. 10397-10410 14 p.

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11 Citations (Scopus)
258 Downloads (Pure)

Collection and characterisation of bacterial membrane proteins

Saidijam, M., Psakis, G., Clough, J. L., Meuller, J., Suzuki, S., Hoyle, C. J., Palmer, S. L., Morrison, S. M., Pos, M. K., Essenberg, R. C., Maiden, M. C. J., Abu-bakr, A., Baumberg, S. G., Neyfakh, A. A., Griffith, J. K., Stark, M. J., Ward, A., O'Reilly, J., Rutherford, N. G., Phillips-Jones, M. K. & 4 others, Henderson, P. J. F., von Heijne, G. (ed.), Rydstrom, J. (ed.) & Brzezinski, P. (ed.), 27 Nov 2003, In : FEBS Letters. 555, 1, p. 170-5 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

Agostinho, A., Meier, B., Sonneville, R., Jagut, M., Woglar, A., Blow, J., Jantsch, V. & Gartner, A., 18 Jul 2013, In : PLoS Genetics. 9, 7, e1003591.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Common genetic variation drives molecular heterogeneity in human iPSCs

Kilpinen, H., Goncalves, A., Leha, A., Afzal, V., Alasoo, K., Ashford, S., Bala, S., Bensaddek, D., Casale, F. P., Culley, O. J., Danecek, P., Faulconbridge, A., Harrison, P. W., Kathuria, A., McCarthy, D. J., McCarthy, S. A., Meleckyte, R., Memari, Y., Moens, N., Soares, F. & 23 others, Mann, A., Streeter, I., Agu, C. A., Alderton, A., Nelson, R., Harper, S., Patel, M., White, A., Patel, S. R., Clarke, L., Halai, R., Kirton, C. M., Kolb-Kokocinski, A., Beales, P. L., Birney, E., Danovi, D., Lamond, A. I., Ouwehand, W. H., Vallier, L., Watt, F. M., Durbin, R., Stegle, O. & Gaffney, D. J., 15 Jun 2017, In : Nature. 546, 7658, p. 370-375 6 p.

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134 Citations (Scopus)
148 Downloads (Pure)
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4 Citations (Scopus)
166 Downloads (Pure)