Gene Regulation and Expression

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Comparative proteomic analysis identifies a role for SUMO in protein quality control

Tatham, M. H., Matic, I., Mann, M. & Hay, R. T., 21 Jun 2011, In : Science Signaling. 4, 178, p. - 12 p., rs4.

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124 Citations (Scopus)

Comparison of bipolar electrosurgical devices with ligatures and endoclips in the rat appendicitis model

Elemen, L., Yazir, Y., Akay, A., Boyacioǧlu, Z., Ceyran, B. & Ceylan, S., 2011, In : Journal of Pediatric Surgery. 46, 10, p. 1923-1929 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Components involved in nuclear pre-mRNA splicing

Krämer, A., Utans, U., Keller, W. & Lamond, A., Jun 1990, In : Molecular Biology Reports. 14, 2-3, p. 199-200 2 p.

Research output: Contribution to journalArticle

Composition of the Survival Motor Neuron (SMN) complex in Drosophila melanogaster

Matera, A. G., Raimer, A. C., Schmidt, C. A., Kelly, J. A., Droby, G. N., Baillat, D., Ten Have, S., Lamond, A. I., Wagner, E. J. & Gray, K. M., 1 Feb 2019, In : G3 : Genes, Genomes, Genetics. 9, 2, p. 491-503 13 p.

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2 Citations (Scopus)
119 Downloads (Pure)

Compton scattering as the explanation of the peculiar X-ray properties of Cyg X-3

Zdziarski, A. A., Misra, R. & Gierliński, M., 21 Feb 2010, In : Monthly Notices of the Royal Astronomical Society. 402, 2, p. 767-775 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Computational Modelling of Cancer Development and Growth: Modelling at Multiple Scales and Multiscale Modelling

Szymańska, Z., Cytowski, M., Mitchell, E., Macnamara, C. K. & Chaplain, M., 1 May 2018, In : Bulletin of Mathematical Biology. 80, 5, p. 1366-1403 38 p.

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7 Citations (Scopus)

Condensed mitotic chromatin is accessible to transcription factors and chromatin structural protiens

Chen, D., Dundr, M., Wang, C., Leung, A., Lamond, A., Misteli, T. & Huang, S., Jan 2005, In : Journal of Cell Biology. 168, 1, p. 41-54 14 p.

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167 Citations (Scopus)

Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis

Vagnarelli, P., Hudson, D. F., Ribeiro, S. A., Trinkle-Mulcahy, L., Spence, J. M., Lai, F., Farr, C. J., Lamond, A. I. & Earnshaw, W. C., 1 Oct 2006, In : Nature Cell Biology. 8, 10, p. 1133-1142 10 p.

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160 Citations (Scopus)

Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation

Renshaw, M. J., Ward, J. J., Kanemaki, M., Natsume, K., Nedelec, F. J. & Tanaka, T. U., 17 Aug 2010, In : Developmental Cell. 19, 2, p. 232-244 13 p.

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45 Citations (Scopus)

Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity

Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J., 1 Apr 2008, In : Cancer Research. 68, 7, p. 2409-2418 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

Ugun-Klusek, A., Tatham, M. H., Elkharaz, J., Constantin-Teodosiu, D., Lawler, K., Mohamed, H., Paine, S. M. L., Anderson, G., John Mayer, R., Lowe, J., Ellen Billett, E. & Bedford, L., Jan 2017, In : Cell Death and Disease. 8, p. 1-12 12 p., e2531.

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13 Citations (Scopus)
154 Downloads (Pure)

Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

Booth, A. J. R., Yue, Z., Eykelenboom, J. K., Stiff, T., Luxton, G. W. G., Hochegger, H. & Tanaka, T., 16 Jul 2019, In : eLife. 8, p. 1-21 21 p., e46902.

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1 Citation (Scopus)
76 Downloads (Pure)

Controlling and co-ordinating chitinase secretion in a Serratia marcescens population

Costa, M. D. A. A., Owen, R. A., Tammsalu, T., Buchanan, G., Palmer, T. & Sargent, F., Nov 2019, In : Microbiology. 165, 11, p. 1233-1244 12 p.

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Control of amino-acid transport coordinates metabolic reprogramming in T cell malignancy

Grzes, K. M., Swamy, M., Hukelmann, J. L., Emslie, E., Sinclair, L. V. & Cantrell, D. A., 26 May 2017, In : Leukemia. 31, p. 2771-2779 9 p.

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11 Citations (Scopus)
136 Downloads (Pure)

Control of chromosomal DNA replication in the early Xenopus embryo

Blow, J. J., 2001, In : EMBO Journal. 20, 13, p. 3293-3297 5 p.

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71 Citations (Scopus)

Control of surface antigen genes in African trypanosomes

Borst, P., Gommersampt, J. H., Lutgerink, J., Ouellette, M., Ten Asbroek, A. L. M. A. & Zomerdijk, J. C. B. M., 1990, In : Biochemical Society Transactions. 18, 5, p. 741-742 2 p.

Research output: Contribution to journalArticle

Control of the terminal step of intracellular membrane fusion by protein phosphatase 1

Peters, C., Andrews, P. D., Stark, M. J. R., Cesaro-Tadic, S., Glatz, A., Podtelejnikov, A., Mann, M. & Mayer, A., 1999, In : Science. 285, 5430, p. 1084-1087 4 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

Narayan, V., Eckert, M., Zylicz, A., Zylicz, M. & Ball, K. L., 18 Sep 2009, In : Journal of Biological Chemistry. 284, 38, p. 25889-25899 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Correction: Human topoisomerase 2 alpha conjugates with SUMO-2 (vol 68, pg 2409, 2008)

Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J., 15 Apr 2008, In : Cancer Research. 68, 8, p. 3076-3076 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Correlative imaging of fluorescent proteins in resin-embedded plant material

Bell, K., Mitchell, S., Paultre, D., Posch, M. & Oparka, K., Apr 2013, In : Plant Physiology. 161, 4, p. 1595-1603 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA

Liu, Y., Freeman, A. D. J., Déclais, A. C., Wilson, T. J., Gartner, A. & Lilley, D. M. J., 22 Dec 2015, In : Cell Reports. 13, 11, p. 2565-2575 11 p.

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22 Citations (Scopus)
129 Downloads (Pure)

CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis

Sonneville, R., Priego Moreno, S., Knebel, A., Johnson, C., Hastie, C. J., Gartner, A., Gambus, A. & Labib, K., 3 Apr 2017, In : Nature Cell Biology. 19, p. 468-479 11 p.

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23 Citations (Scopus)
151 Downloads (Pure)

Cutting Edge: Building bridges between cellular and molecular structural biology

Patwardhan, A., Brandt, R., Butcher, S. J., Collinson, L., Gault, D., Grünewald, K., Hecksel, C., Huiskonen, J. T., Iudin, A., Jones, M. L., Korir, P. K., Koster, A. J., Lagerstedt, I., Lawson, C. L., Mastronarde, D., McCormick, M., Parkinson, H. E., Rosenthal, P. B., Saalfeld, S., Saibil, H. R. & 7 others, Sarntivijai, S., Solanes Valero, I., Subramaniam, S., Swedlow, J. R., Tudose, I., Winn, M. & Kleywegt, G. J., 24 Jul 2017, In : eLife. 6, p. 1-11 11 p., e25835.

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6 Citations (Scopus)
103 Downloads (Pure)

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

Hegarat, N., Crncec, A., Suarez Peredoa Rodriguez, M. F., Iturra, F. E., Gu, Y., Busby, O., Lang, P. F., Barr, A. R., Bakal, C., Kanemaki, M. T., Lamond, A. I., Novak, B., Ly, T. & Hochegger, H., 30 Apr 2020, In : EMBO Journal. p. 1-23 23 p., e104419.

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Cytosolic entry of shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active hrd1p

Li, S., Spooner, R. A., Hampton, R. Y., Lord, J. M. & Roberts, L. M., 2012, In : PLoS ONE. 7, 7, e41119.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Decoding the SUMO signal

Hay, R. T., Apr 2013, In : Biochemical Society Transactions. 41, 2, p. 463-473 11 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Deep Proteome Analysis Identifies Age-Related Processes in C. elegans

Narayan, V., Ly, T., Pourkarimi, E., Brenes Murillo, A., Gartner, A., Lamond, A. & Kenyon, C., 24 Aug 2016, In : Cell Systems. 3, 2, p. 144-159 15 p.

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33 Citations (Scopus)
276 Downloads (Pure)

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

Sharifi, R., Morra, R., Appel, C. D., Tallis, M., Chioza, B., Jankevicius, G., Simpson, M. A., Matic, I., Ozkan, E., Golia, B., Schellenberg, M. J., Weston, R., Williams, J. G., Rossi, M. N., Galehdari, H., Krahn, J., Wan, A., Trembath, R. C., Crosby, A. H., Ahel, D. & 5 others, Hay, R., Ladurner, A. G., Timinszky, G., Williams, R. S. & Ahel, I., 2 May 2013, In : EMBO Journal. 32, 9, p. 1225-1237 13 p.

Research output: Contribution to journalArticle

156 Citations (Scopus)

Degradation ensures integrity

Li, A. & Blow, J. J., 2003, In : Nature. 423, 6942, p. 818-9 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Depth Evaluation of Soft Tissue Mimicking Phantoms Using Surface Acoustic Waves

Li, C., Li, S., Wei, C., Wang, R. K. & Huang, Z., 2015, In : Physics Procedia. 63, p. 177-181 5 p.

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1 Citation (Scopus)
140 Downloads (Pure)

Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template

Neelsen, K. J., Zanini, I. M. Y., Mijic, S., Herrador, R., Zellweger, R., Chaudhuri, A. R., Creavin, K., Blow, J. J. & Lopes, M., 1 Dec 2013, In : Genes and Development. 27, 23, p. 2537-2542 6 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision

Davidson, I. F., Li, A. & Blow, J. J., Nov 2006, In : Molecular Cell. 24, 3, p. 433-443 11 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Detection and Mitigation of Spurious Antisense RNA-seq Reads with RoSA

Mourão, K., Schurch, N. J., Lukoszek, R., Froussios, K., Mackinnon, K., Duc, C., Simpson, G. & Barton, G., 7 Jun 2019, In : F1000 Research. 8, p. 1-7 7 p., 819.

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Detection of protein SUMOylation in vivo

Tatham, M. H., Rodriguez, M. S., Xirodimas, D. P. & Hay, R. T., 2009, In : Nature Protocols. 4, 9, p. 1363-1371 9 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Determinants of Myosin II Cortical Localization during Cytokinesis

Uehara, R., Goshima, G., Mabuchi, I., Vale, R. D., Spudich, J. A. & Griffis, E. R., 22 Jun 2010, In : Current Biology. 20, 12, p. 1080-1085 6 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

Inesta-Vaquera, F., Chaugule, V. K., Galloway, A., Chandler, L., Rojas-Fernandez, A., Weidlich, S., Peggie, M. & Cowling, V., 18 Jun 2018, In : Life Science Alliance. 1, 3, 18 p., e201800092.

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9 Citations (Scopus)
137 Downloads (Pure)

Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis

Matai, L., Sarkar, G. C., Chamoli, M., Malik, Y., Kumar, S. S., Rautela, U., Jana, N. R., Chakraborty, K. & Mukhopadhyay, A., 27 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17383-17392 10 p.

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8 Citations (Scopus)
87 Downloads (Pure)

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo

Xirodimas, D., Saville, M. K., Edling, C., Lane, D. & Lain, S., 2001, In : Oncogene. 20, 36, p. 4972-4983 12 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)

Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei

Ferreira, J. A., Carmo-Fonseca, M. & Lamond, A. I., 1 Jul 1994, In : Journal of Cell Biology. 126, 1, p. 11-23 13 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Directed proteomic analysis of the human nucleolus

Andersen, J. S., Lyon, C. E., Fox, A. H., Leung, A. K. L., Lam, Y. W., Steen, H., Mann, M. & Lamond, A. I., Jan 2002, In : Current Biology. 12, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

756 Citations (Scopus)

Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity

Kasprzyk, R., Fido, M., Mamot, A., Wanat, P., Smietanski, M., Kopcial, M., Cowling, V., Kowalska, J. & Jemielity, J., 7 Apr 2020, In : Chemistry: a European Journal.

Research output: Contribution to journalArticle

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

Lleres, D., Denegri, M., Biggiogera, M., Ajuh, P. & Lamond, A. I., Jun 2010, In : EMBO Reports. 11, 6, p. 445-451 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Direct Monitoring of Protein O-GlcNAcylation by High-Resolution Native Mass Spectrometry

Leney, A. C., Rafie, K., Van Aalten, D. M. F. & Heck, A. J. R., 18 Aug 2017, In : ACS Chemical Biology. 12, 8, p. 2078-2084 7 p.

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6 Citations (Scopus)
133 Downloads (Pure)

Direct non transcriptional role of NF-Y in DNA replication

Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C., 1 Apr 2016, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

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8 Citations (Scopus)
129 Downloads (Pure)

Direct observation of DNA distortion by the RSC complex

Lia, G., Praly, E., Ferreira, H., Stockdale, C., Tse-Dinh, Y. C., Dunlap, D., Croquette, V., Bensimon, D. & Owen-Hughes, T., Feb 2006, In : Molecular Cell. 21, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Discovery, in vivo activity and mechanism of action of a small-molecule p53 activator

Lain, S., Hollick, J. J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Mathers, J., Holland, S. J., Stark, M. J. R., Pass, G., Woods, J., Lane, D. P. & Westwood, N. J., 6 May 2008, In : Cancer Cell. 13, 5, p. 454-463 10 p.

Research output: Contribution to journalArticle

366 Citations (Scopus)

Discovery of an unconventional centromere in budding yeast redefines evolution of point centromeres

Kobayashi, N., Suzuki, Y., Schoenfeld, L., Müller, C., Nieduszynski, C., Wolfe, K. & Tanaka, T., 3 Aug 2015, In : Current Biology. 25, 15, p. 2026-2033 8 p.

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18 Citations (Scopus)
185 Downloads (Pure)

Disease induced dynamics in host-parasitoid systems: chaos and coexistence

Preedy, K. F., Schofield, P. G., Chaplain, M. A. J. & Hubbard, S. F., 2007, In : Journal of the Royal Society Interface. 4, 14, p. 463-471 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Displacement affinity chromatography of protein phosphatase one (PP1) complexes

Moorhead, G. B. G., Trinkle-Mulcahy, L., Nimick, M., De Wever, V., Campbell, D. G., Gourlay, R., Lam, Y. W. & Lamond, A. I., 1 Jan 2008, In : BMC Biochemistry. 9, 1

Research output: Contribution to journalArticle

49 Citations (Scopus)

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

Kumar, A., Aguirre, J. D., Condos, T. E. C., Martinez-Torres, R. J., Chaugule, V. K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D. E., Barber, K. R., Shaw, G. S. & Walden, H., 14 Oct 2015, In : EMBO Journal. 34, 20, p. 2506-2521 16 p.

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86 Citations (Scopus)
342 Downloads (Pure)