Gene Regulation and Expression

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Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility

Griffis, E. R., Craige, B., Dimaano, C., Ullman, K. S. & Powers, M. A., 2004, In : Molecular Biology of the Cell. 15, 4, p. 1991-2002 12 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Distinct subsets of Sit4 holophosphatases are required for inhibition of saccharomyces cerevisiae growth by rapamycin and zymocin

Jablonowski, D., Taeubert, J-E., Baer, C., Stark, M. J. R. & Schaffrath, R., Nov 2009, In : Eukaryotic Cell. 8, 11, p. 1637-1647 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

DNA-binding regulates site-specific ubiquitination of IRF-1

Landré, V., Pion, E., Narayan, V., Xirodimas, D. P. & Ball, K. L., 1 Feb 2013, In : Biochemical Journal. 449, 3, p. 707-717 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

DNA repair factor APLF is a histone chaperone

Mehrotra, P. V., Ahel, D., Ryan, D. P., Weston, R., Wiechens, N., Kraehenbuehl, R., Owen-Hughes, T. & Ahel, I., 7 Jan 2011, In : Molecular Cell. 41, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

DNA replication: stable driving prevents fatal smashes

Donaldson, A. D. & Blow, J. J., 2001, In : Current Biology. 11, 23, p. R979-R982 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

DNA replication and its control

Blow, J. J., Apr 1989, In : Current Opinion in Cell Biology. 1, 2, p. 263-267 5 p.

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2 Citations (Scopus)

DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts

Mahbubani, H. M., Paull, T., Elder, J. K. & Blow, J. J., 11 Apr 1992, In : Nucleic Acids Research. 20, 7, p. 1457-1462 6 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

DNA replication licensing in somatic and germ cells

Eward, K. L., Obermann, E. C., Shreeram, S., Loddo, M., Fanshawe, T., Williams, C., Jung, H-I., Prevost, A. T., Blow, J. J., Stoeber, K. & Williams, G. H., 2004, In : Journal of Cell Science. 117, Pt 24, p. 5875-86 12 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

Narayan, V., Pion, E., Landré, V., Müller, P. & Ball, K. L., 7 Jan 2011, In : Journal of Biological Chemistry. 286, 1, p. 607-619 13 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes

Alabert, C., Loos, C., Voelker-Albert, M., Graziano, S., Forné, I., Reveron-Gomez, N., Schuh, L., Hasenauer, J., Marr, C., Imhof, A. & Groth, A., 28 Jan 2020, In : Cell Reports. 30, 4, p. 1223-1234.e8 21 p.

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Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

McIntosh, D. & Blow, J. J., Oct 2012, In : Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress

Ge, X. Q., Jackson, D. A. & Blow, J. J., 15 Dec 2007, In : Genes & Development. 21, 24, p. 3331-3341 11 p.

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340 Citations (Scopus)

Dose-dependent effects of Allopurinol on human foreskin fibroblast cell and human umbilical vein endothelial cell under hypoxia

Sun, Y., George, J. & Rocha, S., 1 Apr 2015, In : PLoS ONE. 10, 4, 12 p., e0123649.

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6 Citations (Scopus)
129 Downloads (Pure)

Dss1 is a 26S proteasome ubiquitin receptor

Paraskevopoulos, K., Kriegenburg, F., Tatham, M. H., Rösner, H. I., Medina, B., Larsen, I. B., Brandstrup, R., Hardwick, K. G., Hay, R. T., Kragelund, B. B., Hartmann-Petersen, R. & Gordon, C., 6 Nov 2014, In : Molecular Cell. 56, 3, p. 453-461 9 p.

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44 Citations (Scopus)
133 Downloads (Pure)

Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines

Liovic, M., Lee, B., Tomic-Canic, M., D'Alessandro, M., Bolshakov, V. N. & Lane, E. B., 2008, In : Experimental Cell Research. 314, 10, p. 2066-2075 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth

Andrews, P. D. & Stark, M. J. R., 2000, In : Journal of Cell Science. 113, 15, p. 2685-2693 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein

Sleeman, J., Lyon, C. E., Platani, M., Kreivi, J. P. & Lamond, A. I., 15 Sep 1998, In : Experimental Cell Research. 243, 2, p. 290-304 15 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Dynamic localisation of Ran GTPase during the cell cycle

Hutchins, J. R. A., Moore, W. J. & Clarke, P. R., 18 Sep 2009, In : BMC Cell Biology. 10, p. - 10 p., 66.

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20 Citations (Scopus)

Dynamic organization of splicing factors in adenovirus-infected cells

Bridge, E., Xia, D. X., Carmo-Fonseca, M., Cardinali, B., Lamond, A. I. & Pettersson, U., 1 Jan 1995, In : Journal of Virology. 69, 1, p. 281-290 10 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Dynamic properties of nucleosomes during thermal and ATP-driven mobilization

Flaus, A. & Owen-Hughes, T., 2003, In : Molecular and Cellular Biology. 23, 21, p. 7767-7779 13 p.

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76 Citations (Scopus)

Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells

Vale, R. D., Spudich, J. A. & Griffis, E. R., 7 Sep 2009, In : Journal of Cell Biology. 186, 5, p. 727-738 12 p.

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47 Citations (Scopus)
196 Downloads (Pure)
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25 Citations (Scopus)

Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells

Trinkle-Mulcahy, L., Sleeman, J. E. & Lamond, A. I., 27 Dec 2001, In : Journal of Cell Science. 114, 23, p. 4219-4228 10 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine

Seifert, A., Allan, L. A. & Clarke, P. R., Dec 2008, In : FEBS Journal. 275, 24, p. 6268-6280 13 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression

Müncheberg, S., Hay, R. T., Ip, W. H., Meyer, T., Weiß, C., Brenke, J., Masser, S., Hadian, K., Dobner, T. & Schreiner, S., Jul 2018, In : Journal of Virology. 92, 13, 18 p., e00164-18.

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4 Citations (Scopus)
148 Downloads (Pure)

E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin

MacKay, C., Carroll, E., Ibrahim, A. F. M., Garg, A., Inman, G. J., Hay, R. T. & Alpi, A. F., 15 Apr 2014, In : Cancer Research. 74, 8, p. 2246-2257 12 p.

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Open Access
33 Citations (Scopus)

E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis

Ackermann, L., Schell, M., Pokrzywa, W., Kevei, É., Gartner, A., Schumacher, B. & Hoppe, T., Nov 2016, In : Nature Structural & Molecular Biology. 23, 11, p. 995-1002 8 p.

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12 Citations (Scopus)
692 Downloads (Pure)

Editorial overview

Blow, J. J., 2000, In : Current Opinion in Cell Biology. 12, 6, p. 655-657 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effector-Decoy Pairs: Another Countermeasure Emerging during Host-Microbe Co-evolutionary Arms Races?

Cummins, M. & Huitema, E., 1 May 2017, In : Molecular Plant. 10, 5, p. 662-664 3 p.

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1 Citation (Scopus)
171 Downloads (Pure)

Effects of hypo O-GlcNAcylation on Drosophila development

Mariappa, D. N., Ferenbach, A. & van Aalten, D. M. F., 11 May 2018, In : Journal of Biological Chemistry. 293, 19, p. 7209-7221 13 p.

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5 Citations (Scopus)
112 Downloads (Pure)

Efficient Analysis of Mammalian Polysomes in cells and tissues using Ribo Mega-SEC

Yoshikawa, H., Larance, M., Harney, D. J., Sundaramoorthy, R., Ly, T., Owen-Hughes, T. & Lamond, A. I., 10 Aug 2018, In : eLife. 7, 7, p. 1-26 26 p., e36530.

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2 Citations (Scopus)
122 Downloads (Pure)

Efficient chromosome biorientation and the tension checkpoint in saccharomyces cerevisiae both require Bir1

Makrantoni, V. & Stark, M. J. R., 15 Aug 2009, In : Molecular and Cellular Biology. 29, 16, p. 4552-4562 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei

Zomerdijk, J. C. B. M., Kieft, R. & Borst, P., 1991, In : Nature. 353, 6346, p. 772-775 4 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex

Sutherland, C. M., Hawley, S. A., McCartney, R. R., Leech, A., Stark, M. J. R., Schmidt, M. C. & Hardie, D. G., 5 Aug 2003, In : Current Biology. 13, 15, p. 1299-1305 7 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)

Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4

Mehlgarten, C., Jablonowski, D., Breunig, K. D., Stark, M. J. R. & Schaffrath, R., Sep 2009, In : Molecular Microbiology. 73, 5, p. 869-881 13 p.

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37 Citations (Scopus)

Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification

Fichtner, L., Jablonowski, D., Schierhorn, A., Kitamoto, H. K., Stark, M. J. R. & Schaffrath, R., Sep 2003, In : Molecular Microbiology. 49, 5, p. 1297-307 11 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing

Gillespie, P. J., Khoudoli, G. A., Stewart, G., Swedlow, J. R. & Blow, J. J., 9 Oct 2007, In : Current Biology. 17, 19, p. 1657-62 6 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

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2 Citations (Scopus)

Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial

Chung, S. C. S., Leung, J. W. C., Steele, R. J. C., Crofts, T. J. & Li, A. K., 1988, In : BMJ (Clinical Research Ed.). 296, 6637, p. 1631-1633 3 p.

Research output: Contribution to journalArticle

186 Citations (Scopus)

Enhanced snoMEN Vectors Facilitate Establishment of GFP–HIF-1α Protein Replacement Human Cell Lines

Ono, M., Ono, K., Bensaddek, D., Afzal, V., Biddlestone, J., Ortmann, B., Mudie, S., Boivin, V., S. Scott, M., Rocha, S. & Lamond, A. I., 29 Apr 2016, In : PLoS ONE. 11, 4, 28 p., e0154759.

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1 Citation (Scopus)
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EPR distance measurements in deuterated proteins

Ward, R., Bowman, A., Sozudogru, E., El-Mkami, H., Owen-Hughes, T. & Norman, D. G., Nov 2010, In : Journal of Magnetic Resonance Imaging. 207, 1, p. 164-167 4 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Erratum: Further insights into the mechanism of hypoxia-induced NFκB (Cell Cycle (2011) 10 (879-82))

Melvin, A., Mudie, S. & Rocha, S., 2011, In : Cell Cycle. 10, 12, p. 2041 1 p.

Research output: Contribution to journalArticle

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

Grover, A., Mancini, E., Moore, S., Mead, A. J., Atkinson, D., Rasmussen, K. D., O'Carroll, D., Jacobsen, S. E. W. & Nerlov, C., 10 Feb 2014, In : Journal of Experimental Medicine. 211, 2, p. 181-188 8 p.

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68 Citations (Scopus)
97 Downloads (Pure)

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

Earnshaw, W. C., Allshire, R. C., Black, B. E., Bloom, K., Salmon, E. D., Brinkley, B. R., Brown, W., Cheeseman, I. M., Choo, K. H. A., Copenhaver, G. P., DeLuca, J. G., Luger, K., Desai, A., Oegema, K., Cleveland, D. W., Diekmann, S., Erhardt, S., Fitzgerald-Hayes, M., Foltz, D., Fukagawa, T. & 37 others, Gassmann, R., Maiato, H., Gerlich, D. W., Glover, D. M., Gorbsky, G. J., Harrison, S. C., Heun, P., Hirota, T., Jansen, L. E. T., Karpen, G., Kops, G. J. P. L., Lampson, M. A., Lens, S. M., Losada, A., Maddox, P. S., Margolis, R. L., Masumoto, H., McAinsh, A. D., Mellone, B. G., O'Neill, R. J., Meraldi, P., Musacchio, A., Scott, K. C., Sullivan, B. A., Straight, A. F., Stukenberg, P. T., Sullivan, K. F., Sunkel, C. E., Swedlow, J. R., Walczak, C. E., Warburton, P. E., Westermann, S., Willard, H. F., Wordeman, L., Yanagida, M., Yen, T. J. & Yoda, K., 2013, In : Chromosome Research. 21, 2, p. 101-106 6 p.

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27 Citations (Scopus)

Essential functions of Sds22p in chromosome stability and nuclear localization of PP1

Peggie, M., MacKelvie, S., Bloecher, A., Knatko, E., Tatchell, K. & Stark, M., 2002, In : Journal of Cell Science. 115, 1, p. 195-206 12 p.

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38 Citations (Scopus)

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Rugjee, K. N., An, S. & Ryan, R. P., 30 Jun 2016, In : JoVE: Journal of Visualized Experiments. 112, 7 p., e54115.

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2 Citations (Scopus)
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Establishment of a promoter based chromatin architecture on recently replicated DNA can accommodate variable internucleosome spacing

Fennessy, R. T. & Owen-Hughes, T., 6 Sep 2016, In : Nucleic Acids Research. 44, 15, p. 7189-7203 15 p.

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27 Citations (Scopus)
165 Downloads (Pure)

Establishment of a protein frequency library and its application in the reliable identification of specific protein interaction partners

Boulon, S., Ahmad, Y., Trinkle-Mulcahy, L., Verheggen, C., Cobley, A., Gregor, P., Bertrand, E., Whitehorn, M. & Lamond, A. I., May 2010, In : Molecular & Cellular Proteomics. 9, 5, p. 861-879 19 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Eukaryotic DNA replication reconstituted outside the cell

Blow, J. J., May 1988, In : BioEssays. 8, 5, p. 149-152 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)