Gene Regulation and Expression

  • United Kingdom

Research Output 1985 2020

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Letter
2018
11 Citations (Scopus)
169 Downloads (Pure)

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

Liakath-Ali, K., Mills, E. W., Sequeira, I., Lichtenberger, B. M., Pisco, A. O., Sipilä, K. H., Mishra, A., Yoshikawa, H., Wu, C. C-C., Ly, T., Lamond, A. I., Adham, I. M., Green, R. & Watt, F. M., 11 Apr 2018, In : Nature. 556, p. 376-380 5 p.

Research output: Contribution to journalLetter

Open Access
File
Ribosomes
Homeostasis
Stem Cells
Sirolimus
Quality Control
2017
44 Citations (Scopus)

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Zabala-Letona, A., Arruabarrena-Aristorena, A., Martín-Martín, N., Fernandez-Ruiz, S., Sutherland, J. D., Clasquin, M., Tomas-Cortazar, J., Jimenez, J., Torres, I., Quang, P., Ximenez-Embun, P., Bago, R., Ugalde-Olano, A., Loizaga-Iriarte, A., Lacasa-Viscasillas, I., Unda, M., Torrano, V., Cabrera, D., van Liempd, S. M., Cendon, Y. & 44 others, Polentinos-Castro, E., Murray, S., Revandkar, A., Alimonti, A., Zhang, Y., Barnett, A., Lein, G., Pirman, D., Cortazar, A. R., Arreal, L., Prudkin, L., Astobiza, I., Valcarcel-Jimenez, L., Zuñiga-García, P., Fernandez-Dominguez, I., Piva, M., Caro-Maldonado, A., Sánchez-Mosquera, P., Castillo-Martín, M., Serra, V., Beraza, N., Gentilella, A., Thomas, G., Azkargorta, M., Elortza, F., Farràs, R., Olmos, D., Efeyan, A., Anguita, J., Muñoz, J., Falcón-Pérez, J. M., Barrio, R., Macarulla, T., Mato, J. M., Martinez-Chantar, M. L., Cordon-Cardo, C., Aransay, A. M., Marks, K., Baselga, J., Tabernero, J., Nuciforo, P., Manning, B. D., Marjon, K. & Carracedo, A., 6 Jul 2017, In : Nature. 547, 7661, p. 109-113 22 p.

Research output: Contribution to journalLetter

Adenosylmethionine Decarboxylase
Polyamines
Prostatic Neoplasms
Neoplasms
Metabolomics
2015
164 Citations (Scopus)

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Shlien, A., Campbell, B. B., De Borja, R., Alexandrov, L. B., Merico, D., Wedge, D., Van Loo, P., Tarpey, P. S., Coupland, P., Behjati, S., Pollett, A., Lipman, T., Heidari, A., Deshmukh, S., Avitzur, N., Meier, B., Gerstung, M., Hong, Y., Merino, D. M., Ramakrishna, M. & 31 others, Remke, M., Arnold, R., Panigrahi, G. B., Thakkar, N. P., Hodel, K. P., Henninger, E. E., Göksenin, A. Y., Bakry, D., Charames, G. S., Druker, H., Lerner-Ellis, J., Mistry, M., Dvir, R., Grant, R., Elhasid, R., Farah, R., Taylor, G. P., Nathan, P. C., Alexander, S., Ben-Shachar, S., Ling, S. C., Gallinger, S., Constantini, S., Dirks, P., Huang, A., Scherer, S. W., Grundy, R. G., Durno, C., Aronson, M., Gartner, A. & for the Biallelic Mismatch Repair Deficiency Consortium, 2 Feb 2015, In : Nature Genetics. 47, 3, p. 257-262 6 p.

Research output: Contribution to journalLetter

Mutation
Genes
Neoplasms
DNA Mismatch Repair
DNA-Directed DNA Polymerase
2014
263 Citations (Scopus)

Piezo1 integration of vascular architecture with physiological force

Li, J., Hou, B., Tumova, S., Muraki, K., Bruns, A., Ludlow, M. J., Sedo, A., Hyman, A. J., McKeown, L., Young, R. S., Yuldasheva, N. Y., Majeed, Y., Wilson, L. A., Rode, B., Bailey, M. A., Kim, H. R., Fu, Z., Carter, D. A. L., Bilton, J., Imrie, H. & 8 others, Ajuh, P., Dear, T. N., Cubbon, R. M., Kearney, M. T., Prasad, K. R., Evans, P. C., Ainscough, J. F. X. & Beech, D. J., 13 Nov 2014, In : Nature. 515, 7526, p. 279-82 4 p.

Research output: Contribution to journalLetter

Blood Vessels
Endothelial Cells
Calcium
Haploinsufficiency
Cell Polarity
2012
53 Citations (Scopus)

Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites

Matic, I., Ahel, I. & Hay, R. T., Aug 2012, In : Nature Methods. 9, 8, p. 771-772 2 p.

Research output: Contribution to journalLetter

2009
25 Citations (Scopus)

The Seyfert AGN RX J0136.9-3510 and the spectral state of super Eddington accretion flows

Jin, C., Done, C., Ward, M., Gierliński, M. & Mullaney, J., Sep 2009, In : Monthly Notices of the Royal Astronomical Society: Letters. 398, 1, p. L16-L20 5 p.

Research output: Contribution to journalLetter

active galactic nuclei
accretion
oscillation
H beta line
x rays
2008
43 Citations (Scopus)

Guidelines for reporting the use of gel electrophoresis in proteomics

Gibson, F., Anderson, L., Babnigg, G., Baker, M., Berth, M., Binz, P-A., Borthwick, A., Cash, P., Day, B. W., Friedman, D. B., Garland, D., Gutstein, H. B., Hoogland, C., Jones, N. A., Khan, A., Klose, J., Lamond, A. I., Lemkin, P. F., Lilley, K. S., Minden, J. & 10 others, Morris, N. J., Paton, N. W., Pisano, M. R., Prime, J. E., Rabilloud, T., Stead, D. A., Taylor, C. F., Voshol, H., Wipat, A. & Jones, A. R., Aug 2008, In : Nature Biotechnology. 26, 8, p. 863-864 2 p.

Research output: Contribution to journalLetter

2005
752 Citations (Scopus)

Global analysis of protein phosphorylation in yeast

Ptacek, J., Devgan, G., Michaud, G., Zhu, H., Zhu, X., Fasolo, J., Guo, H., Jona, G., Breitkreutz, A., Sopko, R., McCartney, R. R., Schmidt, M. C., Rachidi, N., Lee, S-J., Mah, A. S., Meng, L., Stark, M. J. R., Stern, D. F., De Virgilio, C., Tyers, M. & 5 others, Andrews, B., Gerstein, M., Schweitzer, B., Predki, P. F. & Snyder, M., 1 Dec 2005, In : Nature. 438, 7068, p. 679-684 6 p.

Research output: Contribution to journalLetter

Yeasts
Phosphorylation
Phosphotransferases
Proteins
Fungal Proteins
1990

Toxin arrest

Stark, M. J. R., 9 Aug 1990, In : Nature. 346, 6284, p. 518-518 1 p.

Research output: Contribution to journalLetter

1988
442 Citations (Scopus)

A role for the nuclear envelope in controlling DNA replication within the cell cycle

Blow, J. J. & Laskey, R. A., 7 Apr 1988, In : Nature. 332, 6164, p. 546-548 3 p.

Research output: Contribution to journalLetter

Nuclear Envelope
DNA Replication
Cell Cycle
Mitosis
DNA