Gene Regulation and Expression

  • United Kingdom

Research Output 1985 2020

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Review article
2019
4 Citations (Scopus)
49 Downloads (Pure)

mRNA cap regulation in mammalian cell function and fate

Galloway, A. & Cowling, V., Mar 2019, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1862, 3, p. 270-279 10 p.

Research output: Contribution to journalReview article

Open Access
File
Cells
Messenger RNA
RNA Polymerase II
RNA
Cell Physiological Phenomena
2 Citations (Scopus)

Nucleosome remodelling: structural insights into ATP-dependent remodelling enzymes

Sundaramoorthy, R., Apr 2019, In : Essays in Biochemistry. 63, 1, p. 45-58 14 p.

Research output: Contribution to journalReview article

Nucleosomes
Adenosine Triphosphate
Chromatin Assembly and Disassembly
DNA sequences
Enzymes

Signal enhanced proteomics: a biological perspective on dissecting the functional organisation of cell proteomes

Bensaddek, D., Nicolas, A. & Lamond, A. I., Feb 2019, In : Current Opinion in Chemical Biology. 48, p. 114-122 9 p.

Research output: Contribution to journalReview article

Proteome
Proteomics
Proteins
Chemical Fractionation
Cells
2017
36 Citations (Scopus)
124 Downloads (Pure)

Hypoxia and inflammation in Cancer, focus on HIF and NF-κB

D'Ignazio, L., Batie, M. & Rocha, S., 9 May 2017, In : Biomedicines. 5, 2, 23 p., 21.

Research output: Contribution to journalReview article

Open Access
File
Crosstalk
Transcription Factors
Inflammation
Neoplasms
Chemical activation
8 Citations (Scopus)
132 Downloads (Pure)

Regulation and function of CMTR1-dependent mRNA cap methylation

Inesta-Vaquera, F. & Cowling, V. H., Nov 2017, In : Wiley Interdisciplinary Reviews: RNA. 8, 6, p. 1-6 6 p., e1450.

Research output: Contribution to journalReview article

Open Access
File
Methylation
Ribose
Innate Immunity
Messenger RNA
Nucleotides
8 Citations (Scopus)
120 Downloads (Pure)

Regulation of mRNA capping in the cell cycle

Aregger, M. & Cowling, V. H., 2 Jan 2017, In : RNA Biology. 14, 1, p. 11-14 4 p.

Research output: Contribution to journalReview article

Open Access
File
Cell Cycle
Messenger RNA
Methyltransferases
Phosphorylation
Cyclin B1
2014
24 Citations (Scopus)

A perspective on proteomics in cell biology

Ahmad, Y. & Lamond, A. I., Apr 2014, In : Trends in Cell Biology. 24, 4, p. 257-264 8 p.

Research output: Contribution to journalReview article

Open Access
Proteomics
Cell Biology
Mass Spectrometry
Proteins
Technology
2013
10 Citations (Scopus)

Three wise centromere functions: see no error, hear no break, speak no delay

Tanaka, T. U., Clayton, L. & Natsume, T., Dec 2013, In : EMBO Reports. 14, 12, p. 1073-1083 11 p.

Research output: Contribution to journalReview article

Centromere
Kinetochores
Microtubules
Chromosomes
Chromosome Segregation
2012
74 Citations (Scopus)

Chromatin as an oxygen sensor and active player in the hypoxia response

Melvin, A. & Rocha, S., Jan 2012, In : Cellular Signalling. 24, 1, p. 35-43 9 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

Ganguly, N., 2012, In : Cellular Oncology. 35, 2, p. 67-76 10 p.

Research output: Contribution to journalReview article

2011
66 Citations (Scopus)

Mechanisms for ATP-dependent chromatin remodelling: the means to the end

Flaus, A. & Owen-Hughes, T., Oct 2011, In : FEBS Journal. 278, 19, p. 3579-3595 17 p.

Research output: Contribution to journalReview article

56 Citations (Scopus)

Snf2-family proteins: chromatin remodellers for any occasion

Ryan, D. P. & Owen-Hughes, T., Oct 2011, In : Current Opinion in Chemical Biology. 15, 5, p. 649-656 8 p.

Research output: Contribution to journalReview article

2010
77 Citations (Scopus)

Kinetochore-microtubule interactions: steps towards bi-orientation

Tanaka, T. U., 15 Dec 2010, In : EMBO Journal. 29, 24, p. 4070-4082 13 p.

Research output: Contribution to journalReview article

78 Citations (Scopus)

Post-translational modification by SUMO

Hannoun, Z., Greenhough, S., Jaffray, E., Hay, R. T. & Hay, D. C., 30 Dec 2010, In : Toxicology. 278, 3, p. 288-293 6 p.

Research output: Contribution to journalReview article

530 Citations (Scopus)

The Nucleolus under Stress

Boulon, S., Westman, B. J., Hutten, S., Boisvert, F-M. & Lamond, A. I., 22 Oct 2010, In : Molecular Cell. 40, 2, p. 216-227 12 p.

Research output: Contribution to journalReview article

2009
175 Citations (Scopus)

An additional role for SUMO in ubiquitin-mediated proteolysis

Geoffroy, M-C. & Hay, R. T., Aug 2009, In : Nature Reviews Molecular Cell Biology. 10, 8, p. 564-568 5 p.

Research output: Contribution to journalReview article

76 Citations (Scopus)

Bioimage informatics for experimental biology

Swedlow, J. R., Goldberg, I. G., Eliceiri, K. W. & OME Consortium, 2009, In : Annual Review of Biophysics. 38, p. 327-346 20 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)
276 Downloads (Pure)

Open source bioimage informatics for cell biology

Swedlow, J. R. & Eliceiri, K. W., Nov 2009, In : Trends in Cell Biology. 19, 11, p. 656-660 5 p.

Research output: Contribution to journalReview article

File
113 Citations (Scopus)

Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

Greiss, S. & Gartner, A., Nov 2009, In : Molecules and Cells. 28, 5, p. 407-415 9 p.

Research output: Contribution to journalReview article

2008
27 Citations (Scopus)

Bi-orienting chromosomes: acrobatics on the mitotic spindle

Tanaka, T. U., Dec 2008, In : Chromosoma. 117, 6, p. 521-533 13 p.

Research output: Contribution to journalReview article

81 Citations (Scopus)

Kinetochore-microtubule interactions: the means to the end

Tanaka, T. U. & Desai, A., Feb 2008, In : Current Opinion in Cell Biology. 20, 1, p. 53-63 11 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Nuclear functions in space and time: Gene expression in a dynamic, constrained environment

Trinkle-Mulcahy, L. & Lamond, A. I., 18 Jun 2008, In : FEBS Letters. 582, 14, p. 1960-1970 11 p.

Research output: Contribution to journalReview article

157 Citations (Scopus)

Regulation of gene expression by hypoxia

Kenneth, N. S. & Rocha, S., 15 Aug 2008, In : Biochemical Journal. 414, 1, p. 19-29 11 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)

Replication forks, chromatin loops and dormant replication origins

Blow, J. J. & Ge, X. Q., 2008, In : Genome Biology. 9, 12, p. - 4 p., 244.

Research output: Contribution to journalReview article

151 Citations (Scopus)

Replication licensing and cancer -: a fatal entanglement?

Blow, J. J. & Gillespie, P. J., Oct 2008, In : Nature Reviews Cancer. 8, 10, p. 799-806 8 p.

Research output: Contribution to journalReview article

2006
94 Citations (Scopus)

Mitotic phosphatases: no longer silent partners

Trinkle-Mulcahy, L. & Lamond, A. I., 1 Dec 2006, In : Current Opinion in Cell Biology. 18, 6, p. 623-631 9 p.

Research output: Contribution to journalReview article

Phosphoprotein Phosphatases
Phosphoric Monoester Hydrolases
Dual-Specificity Phosphatases
Centrosome
Chromosome Segregation
2005
243 Citations (Scopus)

Cajal bodies: A long history of discovery

Cioce, M. & Lamond, A. I., 10 Nov 2005, In : Annual Review of Cell and Developmental Biology. 21, p. 105-131 27 p.

Research output: Contribution to journalReview article

Neurodegenerative Diseases
Cell Cycle
RNA
Pathology
Neoplasms
2004
16 Citations (Scopus)

Nuclear organisation and subnuclear bodies.

Platani, M. & Lamond, A. I., 2004, In : Progress in molecular and subcellular biology. 35, p. 1-22 22 p.

Research output: Contribution to journalReview article

2003
121 Citations (Scopus)

Bioinformatic analysis of the nucleolus

Leung, A. K. L., Andersen, J. S., Mann, M. & Lamond, A. I., 15 Dec 2003, In : Biochemical Journal. 376, 3, p. 553-569 17 p.

Research output: Contribution to journalReview article

Bioinformatics
Computational Biology
Proteome
Ribosomes
Organelles
160 Citations (Scopus)

Large-scale proteomic analysis of the human spliceosome

Rappsilber, J., Ryder, U., Lamond, A. I. & Mann, M., 2003, In : Genome Research. 13, 1, p. 1231-1245 15 p.

Research output: Contribution to journalReview article

Spliceosomes
Proteomics
RNA Splicing
Proteins
RNA Precursors
57 Citations (Scopus)

Metastases to the breast revisited: radiological-histopathological correlation

Bartella, L., Kaye, J., Perry, N. M., Malhotra, A., Evans, D., Ryan, D., Wells, C. & Vinnicombe, S. J., Jul 2003, In : Clinical Radiology. 58, 7, p. 524-31 8 p.

Research output: Contribution to journalReview article

Breast
Neoplasm Metastasis
Breast Neoplasms
Unnecessary Procedures
Neoplasms
689 Citations (Scopus)

Nuclear speckles: A model for nuclear organelles

Lamond, A. I. & Spector, D. L., 1 Aug 2003, In : Nature Reviews Molecular Cell Biology. 4, 8, p. 605-612 8 p.

Research output: Contribution to journalReview article

Organelles
Catalytic Domain
Electron Microscopy
Proteins
Fluorescence
69 Citations (Scopus)

The dynamics of the nucleolus

Leung, A. K. L. & Lamond, A. I., 2003, In : Critical Reviews in Eukaryotic Gene Expression. 13, 1, p. 39-54 16 p.

Research output: Contribution to journalReview article

Proteome
5.8S Ribosomal RNA
Proteins
28S Ribosomal RNA
18S Ribosomal RNA
2002
37 Citations (Scopus)

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

Zhang, C., Golderg, M. W., Moore, W. J., Allen, T. D. & Clarke, P. R., 1 Nov 2002, In : European Journal of Cell Biology. 81, 11, p. 623-633 11 p.

Research output: Contribution to journalReview article

Nuclear Pore
Nuclear Envelope
Chromatin
Guanosine Triphosphate
Membranes
88 Citations (Scopus)

Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis

Vosper, H., Khoudoli, G. A., Graham, T. L. & Palmer, C. N. A., 27 Aug 2002, In : Pharmacology and Therapeutics. 95, 1, p. 47-62 16 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Hyperlipidemias
Atherosclerosis
Pharmaceutical Preparations
Lipids

Steps leading to the initiation of replication: Where we are and where we may be going

Woodward, A., Li, A. & Blow, J. J., Jun 2002, In : Chemtracts. 15, 6, p. 289-312 24 p.

Research output: Contribution to journalReview article

1996
44 Citations (Scopus)

The role of carbohydrate in sperm-ZP3 adhesion

Chapman, N. R. & Barratt, C. L., 1 Oct 1996, In : Molecular Human Reproduction. 2, 10, p. 767-774 8 p.

Research output: Contribution to journalReview article

167 Citations (Scopus)

Yeast protein serine/threonine phosphatases: Multiple roles and diverse regulation

Stark, M. J. R., 1996, In : Yeast. 12, 16, p. 1647-1675 29 p.

Research output: Contribution to journalReview article

1994
12 Citations (Scopus)

Genetic analyses of yeast protein serine/threonine phosphatases

Stark, M. J. R., Black, S., Sneddon, A. A. & Andrews, P. D., 1 Apr 1994, In : FEMS Microbiology Letters. 117, 2, p. 121-130 10 p.

Research output: Contribution to journalReview article

1990
141 Citations (Scopus)

The plasmid-encoded killer system of Kluyveromyces lactis: A review

Stark, M. J. R., Boyd, A., Mileham, A. J. & Romanos, M. A., 1990, In : Yeast. 6, 1, p. 1-29 29 p.

Research output: Contribution to journalReview article