Molecular and Clinical Medicine

Projects

Projects per year 1999 2010 2012 2013 2014 2015 2016 2027

• 35 Not started
• 55 Active
• 357 Finished

Projects per year

Search results

• Active

  Defining Stromal Biology In The Pathogenesis Of Oesophageal Cancer To Create A Novel Biomarker Signature To Aid Diagnosis, Prognosis And Treatment Strategies

  Kang, L., McLean, M. H. & Walsh, S.

  15/05/23 → 14/11/24

  Project: Research

• Implementation and Validation of Quantitative Lysosome-specific GCase Assays in Cell Lines and Human Peripheral Blood for use in Clinical Samples

  Alessi, D. & Sammler, E.

  1/03/23 → 31/08/24

  Project: Research

• Neurodegeneration and Bone Health in SHHEC

  Belch, J. & Fitton, C.

  The Institute of Cardiovascular Research

  8/02/23 → 7/02/25

  Project: Research

• UK Keratinocyte Cancer Collaborative: Cutaneous SCC Atlas And Biorepository (Joint with University of Cambridge, NHS Greater Glasgow and Clyde, Norfolk and Norwich University Hospital and Gloucestershire Hospitals NHS Foundation Trust) (BSF National Keratinocyte Cancer Research Award 2021)

  Proby, C.

  British Skin Foundation

  31/01/23 → 30/01/26

  Project: Research

• Establishing Predictors Of Response To Chemotherapy In Advanced Gastroesophageal Adenocarcinoma - PostHoc Analysis Of The GO2 Trial

  Baxter, M. & Petty, R.

  1/01/23 → 31/03/24

  Project: Research

• GREAT-2: A phase 2 trial of Gremubamab compared to placebo in participants with bronchiectasis and chronic Pseudomonas aeruginosa infection

  Chalmers, J.

  1/11/22 → 31/10/25

  Project: Research

• Targeting Cilia Dysfunction As A Therapeutic Strategy For Bronchiectasis

  Shoemark, A.

  British Lung Foundation

  1/10/22 → 30/09/27

  Project: Research

• Inflammation And Salt-Inducible Kinases - A Potential Novel Therapeutic Strategy In Patients With Heart Failure

  Arthur, S., Khan, F. & Mordi, I.

  1/08/22 → 31/01/24

  Project: Research

  • Metformin 100%
  • Cardiovascular Diseases 67%
  • Clinical Studies 64%
  • Type 2 Diabetes Mellitus 23%
  • Sodium-Glucose Transporter 2 Inhibitors 22%

• The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC 3)

  Chalmers, J.

  1/07/22 → 30/06/25

  Project: Research

• LRRK2 Kinase Activity and Global Proteomic Markers in the Gut of PD and IBD Patients (Joint with Icahn School of Medicine Mount Sinai New York & Department Of Pathology & Immunology, Washington University School of Medicine)

  Alessi, D. & Sammler, E.

  1/07/22 → 31/12/23

  Project: Research

• The iDiabetes Platform - Enhanced Phenotyping of Patients With Diabetes For Precision Diagnosis, Prognosis and Treatment (Joint with NHS Education for Scotland and University of Aberdeen)

  Bell, S., Croudace, T., Cunningham, S., Dillon, J., Doney, A., Donnan, P., Farre, A., Lang, C., McCrimmon, R., Mordi, I., Palmer, C. & Pearson, E.

  1/05/22 → 30/04/26

  Project: Research

• Does Apathy Predict Outcomes From Ultrasound Thalamotomy For Parkinson's And Essential Tremor? A Multimodel Clinical And Functional Imaging Study

  Gilbertson, T., Mackenzie, G. & Steele, D.

  1/05/22 → 30/04/25

  Project: Research

• Is Neutrophil Inflammatory Phenotype Regulated By Olfactomedin-4 In Bronchiectasis (Clinical Academic Fellowship)

  Chalmers, J. & Shoemark, A.

  1/04/22 → 31/03/25

  Project: Research

• A Randomised Controlled Trial Of A Facilitated Home-Based Rehabilitation Intervention In Patients With Heart Failure With Preserved Ejection Fraction And Their Caregivers: The REACH-HFpEF Study (Joint with NHST)

  Chalmers, J. & Mordi, I.

  GlaxoSmithKline, National Institute for Health Research

  1/03/22 → 31/12/25

  Project: Research

• ELEVATE: Temozolomide and Nivolumab In MGMT Deficient Oesophagogastric Cancer (Site Agreement via NHS Tayside)

  Petty, R.

  1/11/21 → 29/02/24

  Project: Research

• ORION-4

  Mackenzie, I.

  1/11/21 → 30/04/27

  Project: Research

• HCV in Ethiopia

  Dillon, J., Inglis, S., Radley, A. & Speakman, L.

  National Institute for Health Research

  4/10/21 → 3/10/25

  Project: Research

• Real World Handling of Protein Drugs - Exploration, Evaluation and Education (RealHOPE) (joint with Research Institutes of Sweden (lead), Centre for Process Innovation Limited, Lunds University, University College London, University of Padua and 10 other organisations)

  De Paoli, G., MacDonald, T. & Mackenzie, I.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/07/21 → 30/06/25

  Project: Research

  • Ipilimumab 100%
  • Dilution 57%
  • Light 56%
  • University Hospitals 55%
  • Dose 54%

• Inflammatory Drivers Of endothelial Dysfunction In COVID-19

  Chalmers, J. & Khan, F.

  1/07/21 → 30/06/24

  Project: Research

• Differential LRRK2 Dependent Rab Phosphorylation Signatures in Peripheral Blood and Urine in Idiopathic and Monogenetic PD

  Alessi, D. & Sammler, E.

  1/06/21 → 31/08/23

  Project: Research

  • Phospholipids 100%
  • Parkinson Disease 93%
  • Urine 79%
  • bis(monoacylglyceryl)phosphate 66%
  • Mutation 62%

• A Randomised Controlled Trial Of A Facilitated Home-Based Rehabilitation Intervention In Patients With Heart Failure With Preserved Ejection Fraction And Their Caregivers: The REACH-HFpEF (Joint with University of Glasgow, Birmingham, Royal Cornwall Hospital Trust)

  Lang, C.

  National Institute for Health Research

  1/03/21 → 31/08/24

  Project: Research

• Bronchodilators in Bronchiectasis Study (BIBS Study)

  Chalmers, J.

  National Institute for Health Research

  1/02/21 → 31/01/25

  Project: Research

• Understanding and Predicting the Evolution of Antibiotic Resistance in Human Infection (other institutions, joint lead Dundee/Sheffield Uni, Liverpool Uni))

  Chalmers, J.

  Wellcome Trust

  1/02/21 → 31/01/27

  Project: Research

• Identifying and Validating Predictive Biomarkers in Advanced Oesophagael Adenocarcinoma - A Springboard to REAListic Medicine (BE-REAL)

  Baxter, M.

  1/10/20 → 30/09/23

  Project: Research

  • Adenocarcinoma 100%
  • Survival 85%
  • Precision Medicine 83%
  • Esophageal Neoplasms 82%
  • Neoplasms 82%

• Promoting the Detection of Vascular Risk: Scottish Heart and Arterial Risk Prevention (SHARP)

  Begg, A. & Belch, J.

  Sharp

  31/08/20 → 29/06/26

  Project: Research

• Defining the Oxidative Stress-Related Mechanisms by which Activation of the Transcription Factor Nrf2 Arrests and Resolves Liver Fibrosis

  Arthur, S., Dillon, J., Dinkova-Kostova, A., Hayes, J. & Henderson, C.

  Medical Research Council

  1/04/20 → 31/03/24

  Project: Research

  • Oxidative Stress 100%
  • NF-E2-Related Factor 2 53%
  • Basic-Leucine Zipper Transcription Factors 51%
  • Ubiquitin-Protein Ligases 42%
  • Transcription Factors 36%

• Trials@Home: Center of Excellence – Remote Decentralised Clinical Trials (Joint with 30 other participants, University Medical Centre Utrecht as lead)

  MacDonald, T. & Mackenzie, I.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/09/19 → 31/08/24

  Project: Research

  • Clinical Trials 100%
  • Patient Advocacy 42%
  • Interviews 25%
  • Systematic Reviews 21%
  • Learning 21%

• CARdiomyopathy in type 2 DIAbetes mellitus (CARDIATEAM) (Joint with the INSERM as lead, CIBER- Network Centre for Biomedical Research, Luxembourg Institute of Health and 17 others)

  Doney, A., Houston, G., Lang, C., Mordi, I., Palmer, C., Pearson, E. & Trucco, M.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/03/19 → 1/03/24

  Project: Research

• Pollution and Air Quality Management Area (AQMA)

  Belch, J., Chalmers, J. & Geddes, A.

  The Institute of Cardiovascular Research

  1/02/19 → 31/12/25

  Project: Research

• Bench-to-Bedside Parkinson's Disease Research: Biomarkers in LRRK2 (NHS Research Scotland (NRS) and Scottish Universities Scottish Senior Clinical Academic Fellowship Scheme)

  Sammler, E.

  7/01/19 → 30/06/24

  Project: Research

  • Parkinson Disease 100%
  • Leucine 99%
  • Phosphotransferases 81%
  • Phosphorylation 35%
  • Mutation 33%

• EMBARC2 - European Bronchiectasis Registry and Biobank

  Chalmers, J.

  1/12/18 → 1/10/24

  Project: Research

  • Bronchiectasis 100%
  • Chronic Obstructive Pulmonary Disease 24%
  • Sputum 20%
  • Symptom Flare Up 17%
  • Proteomics 14%

• Sonix Touch Echocardiogram:Sir John Fisher

  Belch, J., Choy, A., George, J., Houston, G., Khan, F. & Lang, C.

  1/07/18 → 31/07/27

  Project: Research

• Sonix Touch Echocardiogram - TICR

  Belch, J.

  The Institute of Cardiovascular Research

  1/07/18 → 31/12/25

  Project: Research

  • Air Pollution 100%
  • Nitrous Oxide 88%
  • Information Storage and Retrieval 78%
  • Ischemia 65%
  • Extremities 63%

• Evaluating Population Impact of HCV DAA Treatment as Prevention to People Who Inject Drugs (EPI-TaP) (joint with University of Bristol)

  Dillon, J. & Donnan, P.

  National Institute for Health Research

  1/02/18 → 31/07/24

  Project: Research

  • Hepatitis C 100%
  • Scotland 68%
  • Hepacivirus 60%
  • Pharmaceutical Preparations 44%
  • Antiviral Agents 44%

• Scottish Senior Clinical Fellowship

  Chalmers, J.

  Chief Scientist Office

  1/01/18 → 1/07/23

  Project: Research

  • Bronchiectasis 100%
  • Chronic Obstructive Pulmonary Disease 24%
  • Lung Diseases 22%
  • Allergic Bronchopulmonary Aspergillosis 21%
  • Neisseria 20%

• The British Lung Foundation/GSK Centre for Bronchiectasis Research

  Chalmers, J.

  British Lung Foundation

  1/11/17 → 31/10/27

  Project: Research

  • Bronchiectasis 100%
  • Lung Diseases 43%
  • Neisseria 42%
  • Sputum 35%
  • Macrolides 34%

• Cardiovascular Research: From Biomarkers to Clinical DATA, TICR 2017

  Anderson, A., Belch, J., Choy, A., George, J., Houston, G., Khan, F., Lang, C. & Struthers, A.

  The Institute of Cardiovascular Research

  1/07/17 → 30/06/25

  Project: Research

• Towards a Better Understanding of Cardiovascular Disease

  Belch, J.

  The Institute of Cardiovascular Research

  1/07/17 → 31/12/25

  Project: Research

• Rational Treatment Selection for Merkel Cell Carcinoma (MCC): A Randomised Phase III Multi-centre Trial Comparing Radical Surgery and Radical Radiotherapy as First Definitive Treatment for Primary MCC with an Observational Study for Patients Ineligible for the Randomised Trial

  Proby, C.

  Medical Research Council

  1/06/17 → 31/12/23

  Project: Research

• PLATFORM - Clinical Trial (joint with Royal Marsden)

  Petty, R.

  22/03/17 → 21/07/25

  Project: Research

• Effectiveness of Intravenous Iron Treatment vs Standard Care in Patients with Heart Failure and Iron Deficiency: a Randomised, Open-label Multicentre Trial (IRONMAN) (Joint with Greater Glasgow Health Board)

  Lang, C.

  12/12/16 → 11/06/23

  Project: Research

• Inhaled Antibiotics in Bronchiectasis and Cystic Fibrosis (iABC) (Joint with 19 Partners)

  Chalmers, J. & Shoemark, A.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/09/15 → 30/06/23

  Project: Research

  • Bronchiectasis 100%
  • Lung 16%
  • Sputum 13%
  • Health Care Outcome Assessment 12%
  • Clinical Trials 12%

• TICR Clinical Rooms Infrastructure and Equipment

  Belch, J. & Khan, F.

  The Institute of Cardiovascular Research

  14/01/14 → 31/07/25

  Project: Research

• Clinical Trial Governance: Achieving Quality Improvement

  Belch, J. & George, J.

  1/08/13 → 31/07/25

  Project: Research

• PAD Coalition Account

  Belch, J. & Khan, F.

  1/07/12 → 31/12/25

  Project: Research

• Early Cancer Detection Test (CDT) Lung Screening Programme

  Donnan, P., Fardon, T., McCowan, C., Schembri, S., Sullivan, F. & Treweek, S.

  Scottish Government

  1/06/12 → 30/09/25

  Project: Research

• DIRECT: Diabetes Research on Patient Stratification (joint with 25 other partners)

  Colhoun, H., Houston, G., Morris, A., Palmer, C. & Pearson, E.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/02/12 → 30/06/23

  Project: Research

  • Type 2 Diabetes Mellitus 100%
  • Information Dissemination 35%
  • Metformin 34%
  • Glucose 24%
  • Glucose Tolerance Test 18%

• Barrett's Oesophagus Two Yearly Surveillance Versus Endoscopy at Need: A Randomised Controlled Trial to Estimate Effectiveness and Cost-Effectiveness Study (BOSS)

  Dillon, J.

  19/07/11 → 18/07/24

  Project: Research

• Miller Nurse for TICR

  Baines, C., Belch, J. & Dick, J.

  The Institute of Cardiovascular Research

  1/03/11 → 31/12/25

  Project: Research

  • Air Pollution 100%
  • Nitrous Oxide 88%
  • Information Storage and Retrieval 78%
  • Ischemia 65%
  • Extremities 63%

• Establishment of a Resource for Long-Term Study of Hepatitis C Virus Infection in the UK (Joint with MRC Virology Unit, University of Glasgow)

  Dillon, J. & Quinlan, P.

  Medical Research Council

  1/01/11 → 31/12/25

  Project: Research