Molecular and Clinical Medicine

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Meeting abstract
2019

ADRB2 haplotypes and risk of exacerbations in asthmatic children and young adults treated with long-acting beta 2-agonists: A meta-analysis in the PiCA consortium

Karimi, L., Vijverberg, S. J., Engelkes, M., Hernandez-Pacheco, N., Farzan, N., Soares, P., Francis, B. R., Pino-Yanes, M., Eng, C., Mukhopadhyay, S., Schieck, M., Kabesch, M., Burchard, E. G., Palmer, C. N. A., Turner, S. W., Janssens, H. M., Maitland-Van Der Zee, A-H. & Verhamme, K. M. C., 21 Nov 2019, In : European Respiratory Journal. 54, 63, PA5388.

Research output: Contribution to journalMeeting abstract

Lowering Uric Acid in Normouricaemic Hypertensive Patients Has an Adverse Effect on Left Ventricular Hypertrophy Regression: Mechanistic Proof of the Urate Paradox

Gingles, C., Symon, R., Gandy, S. J., Struthers, A. D., Houston, G., Macdonald, T. M., Lang, C. C., Donnan, P. T. & George, J., 1 Jul 2019, In : Journal of Hypertension. 37, p. e57

Research output: Contribution to journalMeeting abstract

Meta-analysis of inhaled corticosteroids response in children with asthma

Hernandez-Pacheco, N., Vijverberg, S. J., Gorenjak, M., Flores, C., Francis, B., Farzan, N., Corrales, A., Karimi, L., Maroteau, C., Schieck, M., Repnik, K., Perez-Mendez, L., Soares, P., Berce, V., Tavendale, R., Sardon, O., Corcuera, P., Korta, J., Mukhopadhyay, S., Pirmohamed, M. & 8 others, Mc Verhamme, K., Kabesch, M., Hawcutt, D. B., Turner, S., Palmer, C. N., Potocnik, U., Maitland-Van Der Zee, A. H. & Pino-Yanes, M., 28 Sep 2019, In : European Respiratory Journal. 54, 63, PA5434.

Research output: Contribution to journalMeeting abstract

My Diabetes My Way: clinical outcomes impact and user experiences for an electronic personal health record for diabetes

Cunningham, S., Pokrajac, A., Allardice, B., Brillante, M., Wilson, L. & Wake, D., 1 Mar 2019, In : Future Healthcare Journal. 6, Suppl 1, p. 13-13

Research output: Contribution to journalMeeting abstract

Optimizing Chemotherapy for Frail and/or Elderly Patients With Advanced Gastroesophageal Cancer (Agoac): the Go2 Phase Iii Trial

Swinson, D., Hall, P. S., Lord, S. R., Marshall, H., Ruddock, S., Allmark, C., Cairns, D., Waters, J. S., Wadsley, J., Falk, S., Roy, R., Jospeh, M., Nicoll, J., Kamposioras, K., Tillett, T., Cummings, S., Grumett, S. A., Stokes, Z., Waddell, T., Chatterjee, A. & 4 others, Garcia-Alonso, A., Khan, M., Petty, R. & Seymour, M. T., Nov 2019, In : Journal of Geriatric Oncology. 10, 6 Supp. 1, p. S8 1 p., KO2.

Research output: Contribution to journalMeeting abstract

Optimizing chemotherapy for frail and elderly patients (pts) with advanced gastroesophageal cancer (aGOAC): The GO2 phase III trial.

Hall, P. S., Swinson, D., Waters, J. S., Wadsley, J., Falk, S., Roy, R., Tillett, T., Nicoll, J., Cummings, S., Grumett, S. A., Kamposioras, K., Garcia, A., Allmark, C., Marshall, H., Ruddock, S., Katona, E., Velikova, G., Petty, R. D., Grabsch, H. I. & Seymour, M. T., 20 May 2019, In : Journal of Clinical Oncology. 37, 15, p. 4006 1 p.

Research output: Contribution to journalMeeting abstract

Real-world experience of trifluridine/tipiracil in patients with metastatic colorectal cancer: A multicenter United Kingdom study

Stavraka, C., Pouptsis, A., Kabuubi, P., Angelis, V., Baxter, M., Barrie, A., Costa, A., Nizam, A., De Naurois, J., Mikropoulos, C., Hill, M., Graham, J., Harris, V., Bridgewater, J. & Ross, P., 1 Feb 2019, In : Journal of Clinical Oncology. 37, 4, p. 668-668 1 p.

Research output: Contribution to journalMeeting abstract

13 Citations (Scopus)

Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland

Deciphering Developmental Disorders (DDD) Study, Cacciottolo, T. M., Perikari, A., van der Klaauw, A., Henning, E., Stadler, L. K. J., Keogh, J., Farooqi, I. S., Tenin, G., Keavney, B., Ryan, E., Budd, R., Bewley, M., Coelho, P., Rumsey, W., Sanchez, Y., McCafferty, J., Dockrell, D., Walmsley, S., Whyte, M. & 31 others, Liu, Y., Choy, M-K., Tenin, G., Abraham, S., Black, G., Keavney, B., Watkins, S., Robertson, K., Collison, D., Rush, C., Marshall, J., McGowan, R., Fraser, R., Gandhi, S., Cooper, C., Howden, A., Hukelmann, J. L., Cantrell, D. A., Mordi, I., Forteath, C., Wong, A., Mohan, M., Palmer, C., Doney, A., Rena, G., Lang, C., Gray, E. H., Williams, R., Williams, S., Hughes, J. & Davies, J., 5 Sep 2019, In : QJM : an International Journal of Medicine. 112, 9, p. 724-729 6 p., 9.

Research output: Contribution to journalMeeting abstract

Trifluridine/tipiracil in metastatic colorectal cancer: An updated multicentre real-world analysis on efficacy, safety and predictive factors

Stavraka, C., Pouptsis, A., Synowiec, A., Aggelis, V., Satterthwaite, L., Khan, S., Chauhan, M., Holden, C. E., Young, S., Karampera, C., Martinou, M., Mills-baldock, T., Baxter, M., Eccles, B. K., Iveson, T. J., Shiu, K., Hill, M. E., Abdel-raouf, S., Thomas, A. & Ross, P. J., 1 Oct 2019, In : Annals of Oncology. 30, 5, 2 p., mdz246.077.

Research output: Contribution to journalMeeting abstract

Open Access

Urinary desmosine, a biomarker of elastin degradation is significantly elevated and associated with maximum aortic root size and aortic Z-scores in patients with bicuspid aortic valve

Iskandar, Z., Huang, J., Miller, L., Chin, C., Mordi, I., Mcwilliam, C., Goudie, D., Berg, J., Neagoie, A., Lang, C. & Choy, A-M., 26 May 2019, In : Heart. 105, Supplement 6, p. A103-A104 2 p., 126.

Research output: Contribution to journalMeeting abstract

2018

65 The novel plasma biomarker desmosine, a marker of elastin breakdown, is an independent predictor of abdominal aortic aneurysm events independent of aneurysm size

Mordi, I., Forsythe, R., Bown, M., Lang, C., Newby, D. E., Gellatly, C., Chin, C. W. L., McBride, O., Saratzis, A., Iskandar, Z., Chalmers, R., Huang, J. & Choy, A., Jun 2018, In : Heart. 104, Suppl 6, p. A58-59 2 p.

Research output: Contribution to journalMeeting abstract

3 Citations (Scopus)

The novel biomarker plasma desmosine, a marker of elastin breakdown, is an independent predictor of abdominal aortic aneurysm events independent of aneurysm size

Mordi, I., Forsythe, R., Bown, M., Lang, C., Newby, D. E., Gellatly, C., Chin, C. W. L., McBride, O., Saratzis, A., Iskandar, Z., Chalmers, R., Huang, J. & Choy, A., Aug 2018, In : European Heart Journal. 39, Suppl 1, p. 1253-1254 ehy566.P6040.

Research output: Contribution to journalMeeting abstract

2017

Early HTA in Pharmacogenomics: A Case Example in Cardiovascular Drugs

Baranova, E. V., Geenen, J. W., Asselbergs, F. W., Palmer, C. N., de Boer, A., Maitland-van der Zee, A-H. & Hövels, A. M., Aug 2017, In : Pharmacoepidemiology and Drug Safety. 26, S2, p. 264-265 2 p., 436.

Research output: Contribution to journalMeeting abstract

Genome-Wide Association Study of Asthma Exacerbations in European Children Treated with Inhaled Corticosteroids

Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., Soares, P., Karimi, L., Tavendale, R., Berce, V., Repnik, K., Verhamme, K. M. C., Potocnik, U., Mukhopadhyay, S., Pirmohamed, M., Palmer, C. N., Turner, S. W., Hawcutt, D. B., Kabesch, M., Pino-Yanes, M. & 1 others, Maitland-van der Zee, A-H., Aug 2017, In : Pharmacoepidemiology and Drug Safety. 26, p. 25-26

Research output: Contribution to journalMeeting abstract

Homozygous status for the Arg16 variant is associated with increased prescribing of controller asthma medication and increased asthma-related prescribing cost

Soares, P., Fidler, K., Tavendale, R., Turner, S., Lipworth, B., Bremner, S., Palmer, C. N. A. & Mukhopadhyay, S., Dec 2017, In : Clinical and Experimental Allergy. 47, 12, p. 1681-1682 2 p., O.010.

Research output: Contribution to journalMeeting abstract

Interventions to Enhance Medication Adherence in Older Heart Failure Patients - A Systematic Review

Fulton, R., Kroll, T., McMurdo, M., Molloy, G. J. & Witham, M., 16 May 2017, In : Age and Ageing. 46, Supplement 1, p. i25 1 p.

Research output: Contribution to journalMeeting abstract

2016

LATE-BREAKING ABSTRACT: Real life impact of long acting beta-2-agonist withdrawal in controlled step 3 asthma patients

Jabbal, S., Manoharan, A., Anderson, W. & Lipworth, B., 8 Nov 2016, In : European Respiratory Journal. 48, Suppl60

Research output: Contribution to journalMeeting abstract

Ultra-Widefield Ophthalmic Imaging for Biomarker Discovery in Hypertension

Robertson, G., Peto, T., Williams, M., Dhillon, B., Houston, J., Newby, D. E., van Beek, E. J. R., Trucco, E., Fleming, A., van Hemert, J. & MacGillivray, T., Sep 2016, In : Investigative Ophthalmology & Visual Science. 57, 12, p. 1680 1 p.

Research output: Contribution to journalMeeting abstract

Open Access
10 Citations (Scopus)
2015

Heart Rate is not Related to Survival in Patients with Heart Failure and Atrial Fibrillation

Hawkey, S., Levin, D., Mohan, M., Baig, F., Iskandar, Z., Rutherford, L., Lang, C. & Choy, A., Jun 2015, In : Heart. 101, Supplement 4, p. A15-16 28.

Research output: Contribution to journalMeeting abstract

Inferior Vena Cava Dilatation Predicts Mortality and Worsening Renal Function in Patients With Chronic Heart Failure

Iqbal, A. H. M., Soujeri, B., Hawkey, S., Levin, D., Iskandar, Z., Stewart, G., Sloan, J. & Lang, C., 26 Sep 2015, In : Journal of Cardiac Failure. 21, 8, Supplement, p. S70 151.

Research output: Contribution to journalMeeting abstract

2012

Allopurinol use associated with greater functional gains in older rehabilitation patients: a retrospective cohort study

Beveridge, L. A., Ramage, L., McMurdo, M. E. T., George, J. & Witham, M., 2012, In : Age and Ageing. 41, Suppl. 2, p. 65 1 p.

Research output: Contribution to journalMeeting abstract

High admission Barthel scores do not predict lack of benefit from inpatient rehabilitation

Tan, S. C., Ramage, L., McMurdo, M. E. T. & Witham, M., 2012, In : Age and Ageing. 41, Suppl. 2, p. 69 1 p.

Research output: Contribution to journalMeeting abstract

2011

Robust neutralising activity and activation of neutrophil cytotoxic responses mediated by antibodies targeting the HTLV-1 envelope glycoprotein

Kuo, C., Tulloch, L. & Brighty, D. W., 6 Jun 2011, In : Retrovirology. 8, Supplement 1, 1 p., A170.

Research output: Contribution to journalMeeting abstract

Open Access
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2005

Electron microscopy of yeast and bacterial V-ATPases

Nicholson, W., 2005, In : Biophysical Journal. 88, 1, p. 599A 1 p.

Research output: Contribution to journalMeeting abstract

Using the demand-control model of job strain to predict caregiver burden: a longitudinal study

Molloy, G., Johnston, D., Johnston, M., Witham, M., Struthers, A. & McMurdo, M., 2005, In : Psychology and Health. 20, Suppl. 1, p. 176-177 2 p.

Research output: Contribution to journalMeeting abstract