Molecular Cell and Developmental Biology

Projects

Projects per year 2005 2010 2012 2013 2014 2015 2016 2017 2018 2031

• 25 Active
• 57 Not started
• 227 Finished

Projects per year

Search results

• Finished

  Molecular and Cellular Biology 4 Year PhD

  Owen-Hughes, T. (Investigator)

  1/09/14 → 31/08/18

  Project: Research

• Molecular and Cellular Biology 4 Year PhD

  Dale, K. (Investigator) & Owen-Hughes, T. (Investigator)

  1/09/14 → 1/09/18

  Project: Research

• Molecular and Cellular Biology 4 Year PhD

  Owen-Hughes, T. (Investigator)

  1/09/14 → 31/08/18

  Project: Research

  • O-linked N-acetylglucosamine (O-GlcNAc) 100%
  • Protein O-GlcNAcylation 62%
  • Functional Dissection 62%
  • O-GlcNAcylation 50%
  • Genome Recoding 50%

• Expanded Metadatas Support in the Open Microscopy Environments Bio-Formats and OMERO Data Applications

  Swedlow, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  31/08/14 → 28/02/18

  Project: Research

  • Image Data 100%
  • Open Source 76%
  • Data Type 76%
  • Omeros 76%
  • High-content Screening 42%

• Cellular and Molecular Mechanisms Regulating Neuronal Differentiation in Embryos and Adults (Senior Investigator award)

  Storey, K. (Investigator)

  21/07/14 → 31/12/21

  Project: Research

  • Neuromesodermal Progenitors 100%
  • Neural Differentiation 93%
  • Spinal Cord 81%
  • Neural Stem Cell 72%
  • Central Canal 62%

• A Bioimaging UK Network A Scientific Community Defining Strategic Initiatives for UK Bioimaging (Joint with Imperial College London, Kings College London, London Research Institute, Beatson Research Institute, University College London and Universities of Bristol and Durham)

  Swedlow, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/07/14 → 31/12/17

  Project: Research

• RNF4 in the DDr - Identifying the Targets and Mechanism of Action of the SUMO Targeted Ubiquitin Ligase RNF4 in Response to Distinct DNA Lesions (Marie Curie Fellowship)

  Hay, R. (Investigator) & Wright, J. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/07/14 → 19/08/17

  Project: Research

• Development of Live Tissue Imaging Capabilities Using Multiphoton Confocal Microscopy

  Muller, A. (Investigator), Nathke, I. (Investigator), Storey, K. (Investigator) & Weijer, K. (Investigator)

  30/06/14 → 29/06/19

  Project: Research

  • Gastrulation 100%
  • Chick 64%
  • Vertebrates 61%
  • Drosophilidae 51%
  • Adenomatous Polyposis Coli 50%

• Doctoral Training Grant DTG 2013 & 2014

  MacKintosh, C. (Investigator) & Muller, A. (Investigator)

  Medical Research Council

  7/04/14 → 1/10/20

  Project: Research

  • Transcription Factor Nrf2 100%
  • Phosphoinositide 3-kinase (PI3K) 100%
  • Transcriptional Activation 100%
  • Parkinson's Disease 100%
  • Mitochondrial Dysfunction 100%

• Biology and Physics at the Biofilm Surface (Joint with University of Edinburgh)

  Stanley-Wall, N. (Investigator) & van Aalten, D. (Investigator)

  Biotechnology and Biological Sciences Research Council

  31/03/14 → 30/03/17

  Project: Research

  • Biofilm 100%
  • BslA 95%
  • Bacillus subtilis 77%
  • Bacillus Subtilis (B. subtilis) 58%
  • Biofilm-associated Protein 31%

• De-risking Innovative Drug Discovery Projects through Portfolio Management (Confidence in Concept)

  Ferguson, M. (Investigator), Woodland, A. (Investigator) & Wyatt, P. (Investigator)

  Medical Research Council

  1/03/14 → 31/08/15

  Project: Research

  • InhA 100%
  • Penetration Index 100%
  • Functional Complexity 100%
  • Functional Groups 100%
  • Mycobacterium Tuberculosis (M. tb) 100%

• Regulation of Methyl Cap Function

  Cowling, V. (Investigator)

  1/01/14 → 31/12/20

  Project: Research

• Hypoxia Sensing by Chromatin

  Rocha, S. (Investigator)

  1/01/14 → 31/12/14

  Project: Research

• Investigating MRNA Methyl Cap Regulation, Function and Therapeutic Potential (Senior Non-Clinical Fellowship)

  Cowling, V. (Investigator)

  Medical Research Council

  1/01/14 → 31/12/21

  Project: Research

  • RNA 100%
  • Messenger RNA 90%
  • Methyltransferase 78%
  • Guanine 49%
  • RNA Capping 39%

• Photonic Tools for Quantitative Imaging in Cells and Tissues (PHOQUS)

  Cochran, S. (Investigator), Cuschieri, A. (Investigator), Khan, F. (Investigator), Lamond, A. (Investigator), MacDonald, M. (Investigator), McGloin, D. (Investigator), Nathke, I. (Investigator), Rafailov, E. (Investigator), Read, K. (Investigator), Swedlow, J. (Investigator), Swift, S. (Investigator), Tanaka, T. (Investigator) & Weijer, K. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/13 → 31/10/17

  Project: Research

  • Digital Micromirror Device 100%
  • Solid-liquid Transition 50%
  • Pentadecane 50%
  • Metabolic Oscillations 50%
  • Long-chain N-alkanes 50%

• Functional Characterization of Newly Identified Cytoskeletal Binding Proteins in the Control of Actin Myosin Dynamics During Chemotaxis

  Weijer, K. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/11/13 → 30/04/17

  Project: Research

  • Dictyostelium Discoideum 100%
  • Dictyostelium 76%
  • Cell Movement 71%
  • Dynamics 70%
  • Actin 64%

• Anatomy and development of the Adult Spinal Cord Neural Stem Cell Niche (Studentship)

  Storey, K. (Investigator)

  Anatomical Society of GB and Northern Ireland

  1/10/13 → 30/09/16

  Project: Research

• Analysis of Calorie Restriction and its Role in Ageing from Nematodes to Humans (RSE/Scottish Government Personal Research Fellowship co-funded by Marie Curie Actions)

  Lamond, A. (Investigator) & Larance, M. (Investigator)

  Royal Society of Edinburgh

  1/10/13 → 30/09/18

  Project: Research

• Molecular and Cellular Biology PhD Program (4 Year PhD)

  Blow, J. (Investigator) & Owen-Hughes, T. (Investigator)

  2/09/13 → 2/09/17

  Project: Research

  • Lateral Interactions 100%
  • Bacterial Biofilm 100%
  • BslA 100%
  • Biofilm-associated Protein 100%
  • Self-assembly 100%

• Molecular and Cellular Biology PhD Programme (4 Year PhD)

  Owen-Hughes, T. (Investigator)

  2/09/13 → 1/09/17

  Project: Research

• Molecular and Cellular Biology PhD Programme (4 Year PhD)

  Owen-Hughes, T. (Investigator)

  2/09/13 → 1/09/17

  Project: Research

  • Von Hippel-Lindau 100%
  • Procollagen-Proline Dioxygenase 66%
  • Hypoxia-Inducible Factors 66%
  • Proteolysis 55%
  • VH298 45%

• Molecular and Cellular Biology PhD Programme (4 Year PhD)

  Cowling, V. (Investigator) & Owen-Hughes, T. (Investigator)

  2/09/13 → 2/09/17

  Project: Research

• Molecular and Cellular Biology PhD Programme (4 Year PhD)

  Owen-Hughes, T. (Investigator)

  2/09/13 → 1/09/17

  Project: Research

• Development of a Model of Subperineural Injection During Ultrasound Guided Regional Anaesthesia

  Cochran, S. (Investigator), Corner, G. (Investigator), Demore, C. (Investigator), Eisma, R. (Investigator), Felts, P. (Investigator), McLeod, G. (Investigator) & Munimara, S. (Investigator)

  National Institute of Academic Anaesthesia

  1/08/13 → 31/07/14

  Project: Research

• Regulation of the Rho GEF Pebble in Fibroblast Growth Factor Dependent Cell Migration

  Muller, A. (Investigator)

  Medical Research Council

  1/08/13 → 31/07/16

  Project: Research

  • Drosophilidae 100%
  • Complement Factor B 91%
  • Nuclear factor-B 82%
  • Hypoxia 80%
  • Drosophila Melanogaster 80%

• Mutational Signatures of DNA Damage and Repair Process (Joint with University of Cambridge)

  Gartner, A. (Investigator)

  1/08/13 → 31/12/18

  Project: Research

  • Caenorhabditis Elegans 100%
  • DNA Repair Pathways 100%
  • DNA Repair 100%
  • Genome Integrity 62%
  • Germ Cells 60%

• Mass Spec Approach Toward Detection of O/GlcNAc in Atz Brains

  van Aalten, D. (Investigator)

  1/07/13 → 30/06/14

  Project: Research

• Ultrasound in a Needle: Minimally Invasive High Resolution Imaging for Neurosurgery (Healthcare Technology Challenges for Engineering) (Joint with University of Birmingham and Heriot Watt University)

  Cochran, S. (Investigator) & Demore, C. (Investigator)

  Engineering and Physical Sciences Research Council

  1/07/13 → 30/06/15

  Project: Research

• Sonopill: Minimally Invasive Gastrointestinal Diagnosis and Therapy (Joint with University of Glasgow & Heriot Watt University)

  Cochran, S. (Investigator), Corner, G. (Investigator), Cuschieri, A. (Investigator), Nathke, I. (Investigator) & Steele, B. (Investigator)

  Engineering and Physical Sciences Research Council

  27/05/13 → 14/12/18

  Project: Research

  • Capsule Endoscopy 100%
  • Micro-ultrasound 84%
  • Gastrointestinal Tract 70%
  • Small Intestine 70%
  • Endoscope 43%

• How Does Insulin in the Bloodstream Trigger Dephosphorylation of Regulatory Proteins of Cell Morphology and Dopamine Synthesis in the Brain?

  MacKintosh, C. (Investigator)

  Diabetes UK

  1/05/13 → 30/04/16

  Project: Research

• SELFCC: Chromosome Self-clearing Completes Sister Chromatid Separation

  Tanaka, T. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/04/13 → 30/09/18

  Project: Research

  • Kinetochore 100%
  • Microtubule 79%
  • Biorientation 63%
  • Centromere 53%
  • Budding Yeast 52%

• The Scottish eHealth Informatics Research Centre (E-HIRCs) (Joint with Universities of Aberdeen, Glasgow, Edinburgh, Strathclyde, St Andrews & Leicester and ISD)

  Colhoun, H. (Investigator), Donnan, P. (Investigator), Guthrie, B. (Investigator), Jefferson, E. (Investigator), MacDonald, T. (Investigator), McCowan, C. (Investigator), Morris, A. (Investigator), Pearson, E. (Investigator), Sullivan, F. (Investigator) & Swedlow, J. (Investigator)

  Medical Research Council

  1/03/13 → 31/12/18

  Project: Research

  • Scottish 100%
  • Scotland 73%
  • Type 2 Diabetes Mellitus (T2DM) 39%
  • Genome-wide Association Study 30%
  • Coding Variants 28%

• Cognitive Function in the Min Mouse: A Role for the APC Gene in Cognition

  Langston, R. (Investigator) & Nathke, I. (Investigator)

  Anonymous Trust

  1/03/13 → 31/08/14

  Project: Research

• Recycling Polarity - Mechanisms Controlling Stem Cell Polarity in Consecutive Divisions in the Developing Drosophila Central Nervous System (Sir Henry Dale Fellowship)

  Januschke, J. (Investigator) & Storey, K. (Investigator)

  1/02/13 → 30/11/21

  Project: Research

  • Drosophilidae 100%
  • Neuroblast 65%
  • Drosophila Neuroblast 60%
  • Miranda 34%
  • Stem Cells 31%

• SUMO Proteomics in C. Elegans: Germ Line, Meiosis and the DNA Damage Response

  Gartner, A. (Investigator) & Hay, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  15/01/13 → 14/01/16

  Project: Research

• Ultrasound Microscopy for Clinical and Pre-Clinical Tissue Characterisation (Caledonian Research Fund)

  Demore, C. (Investigator)

  Royal Society of Edinburgh

  1/01/13 → 31/03/19

  Project: Research

• Imaging Chromatin Transitions Using High Performance Microscopy

  Owen-Hughes, T. (Investigator) & Swedlow, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/01/13 → 31/12/15

  Project: Research

  • Chromatin 100%
  • High-resolution Imaging 100%
  • Chromatin State 100%
  • Cell Division 100%
  • Genomics 100%

• Dynamics of Fundamental Cellular Processes by Live Cell and Tissue Imaging

  MacDonald, M. (Investigator), McGloin, D. (Investigator), McKenna, S. (Investigator), Storey, K. (Investigator), Swedlow, J. (Investigator) & Weijer, K. (Investigator)

  Medical Research Council

  1/01/13 → 31/12/17

  Project: Research

  • Caenorhabditis Elegans 100%
  • Mitosis 52%
  • Dopaminergic 44%
  • 6-hydroxydopamine (6-OHDA) 42%
  • Trypanosoma 42%

• Cellular Mechanisms of Gastrulation: A Combined Experimental and Modelling Study (Joint with University of Liverpool)

  Weijer, K. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/01/13 → 30/06/16

  Project: Research

  • Gastrulation 100%
  • Chick Embryo 86%
  • Chick 80%
  • Primitive Streak 69%
  • Myosin 65%

• Strategic Award: Wellcome Trust Technology Platform

  Blow, J. (Investigator), Lamond, A. (Investigator) & Owen-Hughes, T. (Investigator)

  1/01/13 → 30/09/18

  Project: Research

  • Proteomics 100%
  • Ubiquitin 96%
  • Proteome 71%
  • Messenger RNA 59%
  • Chromatin 59%

• Molecular Biology of FMDV Replication: Towards New Methods of FMDV Disease Control (joint with Universities of St Andrews, Leeds and Edinburgh and Institute for Animal Health Pirbright) (Strategic Longer Larger Grant)

  Lamond, A. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/01/13 → 31/12/18

  Project: Research

• Mechanism of Poly-SUMO Chain Recognition by the Ubiquitin Ligase RNF4 (joint with Imperial College London)

  Hay, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  21/12/12 → 20/01/16

  Project: Research

  • Ubiquitin 100%
  • RNF4 75%
  • Small Ubiquitin-like Modifier 50%
  • K63-linked Ubiquitin Chains 50%
  • Ubiquitin-like 50%

• Human iPS Cell Collection (Joint with King's College London, Sanger Centre, European Bioinformatics Institute)

  Lamond, A. (Investigator)

  1/11/12 → 1/02/18

  Project: Research

  • Induced Pluripotent Stem Cells (iPSCs) 100%
  • Proteomics 99%
  • Proteome 87%
  • Human Induced Pluripotent Stem Cell 74%
  • Induced Stem Cell 47%

• Determining the Role and Mechanism of Action of SUMO Targeted Ubiquitin Ligase RNF4 in Maintaining Genome Integrity (Senior Investigator Award)

  Hay, R. (Investigator)

  1/10/12 → 31/01/20

  Project: Research

  • Ubiquitin 100%
  • Ubiquitin-like 51%
  • Small Ubiquitin-like Modifier 45%
  • Ubiquitin Ligase 32%
  • Ubiquitin-Conjugating Enzyme 23%

• State of the Art Pulse EPR Instrumentation for Long Range Distance Measurements in Biomacromolecules (Multi-User Equipment Grant) (Joint with University of St Andrews)

  Hunter, B. (Investigator), Keeble, D. (Investigator), Lilley, D. (Investigator), Norman, D. (Investigator) & Owen-Hughes, T. (Investigator)

  24/09/12 → 23/09/17

  Project: Research

  • CHD1 100%
  • Chromatin Remodeling Enzymes 100%
  • Nucleosome 100%
  • Chromatin Remodeling 100%
  • Enzyme 100%

• CeleSUMOMS: SUMO Proteomics in C. Elegans: Focus on Meiosis and the DNA Damage Response (Fellow: Federico Pelisch)

  Hay, R. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  17/09/12 → 16/09/14

  Project: Research

  • Caenorhabditis Elegans 100%
  • Ring Complex 66%
  • Oocyte Meiosis 66%
  • Small Ubiquitin-like Modifier 66%
  • Cell Cycle Progression 66%

• Delineating the Ageing Proteome: Convergence of Ageing Pathways in Caenorhabditis Elegans (Sir Henry Wellcome Fellowship - Vikram Narayan)

  Gartner, A. (Investigator), Lamond, A. (Investigator) & Narayan, V. (Investigator)

  1/09/12 → 30/04/18

  Project: Research

• Fluorescence Resonance Energy Transfer as a Rich Source of Orientational Information in Nucleic Acid Structure

  Lilley, D. (Investigator)

  Engineering and Physical Sciences Research Council

  1/09/12 → 30/06/16

  Project: Research

  • RNA 100%
  • Kink-turn 63%
  • Riboswitch 62%
  • Crystal Structure 43%
  • Ribozyme 43%

• Exploring and Exploiting C. Elegans as a Model to Better Understand Apoptosis Induction; Combined Cytological, Genetic and Proteomics Based Approaches

  Gartner, A. (Investigator)

  1/07/12 → 31/03/16

  Project: Research

  • CMG Helicase 100%
  • Ubiquitylation 100%
  • TRAIP 100%
  • Replisome 100%
  • Mammalian Cell Cycle 100%

• Mechanistic Studies of the Relationship between Xanthine Oxidase Inhibition and HIF

  George, J. (Investigator) & Rocha, S. (Investigator)

  Anonymous Trust

  1/06/12 → 31/05/13

  Project: Research