Molecular Cell and Developmental Biology

Projects

Projects per year 2005 2010 2012 2013 2014 2015 2016 2017 2018 2031

• 25 Active
• 57 Not started
• 227 Finished

Projects per year

Search results

• Finished

  Drosophila ORFeome In Vitro and In Vivo Resource for the Research Community

  Bjorklund, M. (Investigator)

  Biotechnology and Biological Sciences Research Council

  11/05/12 → 10/10/15

  Project: Research

• Christine Demore SUPA Travel Grant

  Cochran, S. (Investigator) & Demore, C. (Investigator)

  16/04/12 → 15/10/12

  Project: Research

• Regulation of mRNA Cap Methylation

  Cowling, V. (Investigator)

  1/04/12 → 31/12/21

  Project: Research

  • CMTR1 100%
  • Cap Formation 100%
  • Influenza-like Illness 100%
  • Phosphorylation 100%
  • MRNA Cap 100%

• Molecular Mechanisms Regulating the Kinetochore-Microtubule Interaction in Mitosis (Principal Research Fellowship)

  Tanaka, T. (Investigator)

  1/04/12 → 30/04/21

  Project: Research

  • Kinetochore 100%
  • Error Correction 49%
  • Budding Yeast 49%
  • Biorientation 43%
  • Centromere 39%

• An Alternative Retinoid Pathway Regulating Vertebrate Neurogenesis

  Storey, K. (Investigator)

  Medical Research Council

  1/03/12 → 31/08/15

  Project: Research

  • Mesodermal 100%
  • Pattern Formation 100%
  • Neural Tube 100%
  • Neural Crest 100%
  • Morphogenesis 100%

• State-of-the-Art Facilities for Structural Biology at the University of Dundee

  Hunter, B. (Investigator), Lilley, D. (Investigator), Owen-Hughes, T. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

  1/03/12 → 28/02/17

  Project: Research

  • Proteolysis Targeting chimera (PROTAC) 100%
  • Crystal Structure 82%
  • Enzyme 73%
  • Proteolysis 60%
  • Degrader 56%

• Circulating Tumour Cells from Colorectal Cancer Patients (The Anne and Normile Baxter Prize for Cancer Research )

  Nathke, I. (Investigator), Quyn, A. (Investigator) & Steele, B. (Investigator)

  1/02/12 → 29/02/12

  Project: Research

• Role of the NF-Kappa-HIF Crosstalk in Inflammation-Mediated Tumour Progression

  Rocha, S. (Investigator)

  1/01/12 → 31/12/14

  Project: Research

• Mechanisms for Remodelling Chromatin (Senior Fellowship Renewal)

  Owen-Hughes, T. (Investigator)

  1/01/12 → 31/05/19

  Project: Research

  • Nucleosome 100%
  • Histone 51%
  • Enzyme 43%
  • Chromatin Remodeling 43%
  • Chromatin 42%

• How to Build a Biofilm

  Stanley-Wall, N. (Investigator) & van Aalten, D. (Investigator)

  1/01/12 → 30/04/15

  Project: Research

  • Biofilm 100%
  • Bacillus subtilis 76%
  • BslA 65%
  • Bacillus Subtilis (B. subtilis) 49%
  • Biofilm Formation 36%

• Structural Characterisation of the Tetrasome and Histone Chaperones (Joint with University of St Andrews)

  Norman, D. (Investigator) & Owen-Hughes, T. (Investigator)

  Medical Research Council

  1/01/12 → 31/12/14

  Project: Research

• The Promyelocytic Leukaemia Protein as a Target in Cancer Therapy (Programme Grant)

  Hay, R. (Investigator)

  1/12/11 → 30/11/16

  Project: Research

  • Sumoylation 100%
  • SUMOylation 75%
  • Proteomics 60%
  • Pol2 50%
  • Smc5 50%

• A Systems Approach to Chemotactic Cell Sorting During Development (Joint with University of Warwick)

  Dhir, R. (Investigator) & Weijer, K. (Investigator)

  1/11/11 → 31/05/15

  Project: Research

  • Primitive Streak 100%
  • Myosin II 100%
  • Cell Shape Change 100%
  • Cell Intercalation 100%
  • Streak Formation 100%

• Accelerating Drug Discovery into Therapeutics and Commercial Benefit (Horizon Fund)

  Gray, D. (Investigator), Hopkins, A. (Investigator), Read, K. (Investigator), Woodland, A. (Investigator) & Wyatt, P. (Investigator)

  1/11/11 → 31/12/13

  Project: Research

• UPStream - European Research Training in the Ubiquitin Proteasome System (joint with 9 other partners)

  Hay, R. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/11 → 31/10/15

  Project: Research

• The Open Microscopy Environment: Image Informatics for Biological Sciences (Joint with Imperial College, Oxford University, Institut Pasteur, Carnegie-Mellon University, University of Wisconsin, Harvard Medical School & University of Edinburgh)

  Swedlow, J. (Investigator)

  1/10/11 → 30/09/16

  Project: Research

  • Kinetochore 100%
  • Image Data 84%
  • Omeros 72%
  • Bacillus Subtilis Biofilm 64%
  • Microtubules 64%

• Sugar Coat: Validation of UDP Galactopyranose Mutase as a Potential Antifungal Target (Clinical PhD Fellowship - Deborah Lockhart)

  Lockhart, D. (Investigator) & van Aalten, D. (Investigator)

  Medical Research Council

  5/09/11 → 4/09/14

  Project: Research

  • Aspergillus Fumigatus 100%
  • Aspergillus fumigatus 66%
  • Cell Wall 44%
  • UDP-galactopyranose mutase 33%
  • N-myristoyltransferase 33%

• Mechanisms of Inflammation and Hypoxia-Induced Responses Mediated by HIF and NF-KB in Cancer (Senior Research Fellowship)

  Lamond, A. (Investigator) & Rocha, S. (Investigator)

  1/08/11 → 1/08/17

  Project: Research

  • Von Hippel-Lindau 100%
  • Procollagen-Proline Dioxygenase 66%
  • Hypoxia-Inducible Factors 66%
  • Proteolysis 55%
  • Hypoxia Response 53%

• Genome-Wide Analysis of Insulin Signalling by Ribosome Profiling

  Bjorklund, M. (Investigator)

  1/03/11 → 31/08/12

  Project: Research

• Discovery and Development of Drug Candidates for Neglected Diseases (joint with industrial partner)

  Brenk, R. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Hopkins, A. (Investigator), Horn, D. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

  1/02/11 → 1/07/17

  Project: Research

  • Visceral Leishmaniasis 100%
  • Trypanosoma Brucei 80%
  • Trypanosoma Cruzi (T. cruzi) 76%
  • N-myristoyltransferase 65%
  • Diseases 64%

• Aref#d: 22422. The Cancer Research-UK Nucleic Acid Structure Research Group: Nucleic Acid Structure and Interactions with Proteins (Programme Grant)

  Lilley, D. (Investigator)

  1/01/11 → 31/12/15

  Project: Research

• Mechanism and Regulation of RNA-directed Chromatin Modification (Career Development Award)

  Bayne, E. (Investigator) & Lamond, A. (Investigator)

  Medical Research Council

  1/01/11 → 31/12/15

  Project: Research

• K-Turn Structure in the Architecture of Functional RNA Molecules

  Lilley, D. (Investigator)

  1/01/11 → 31/12/14

  Project: Research

• Euro-BioImaging: Research Infrastructure for Imaging Technologies in Biological and Biomedical Sciences (joint with 38 other partners)

  Swedlow, J. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/12/10 → 30/11/13

  Project: Research

• SUGABACT: The Role of O-GlcNAc in Bacterial Signal Transduction and Virulence (Fellow: Dr. Francesco Rao)

  Rao, F. (Investigator) & van Aalten, D. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/10 → 31/10/14

  Project: Research

• Mechanism and Inhibition of Chitin Synthesis (Sir Henry Wellcome Fellowship)

  Dorfmueller, H. (Investigator) & van Aalten, D. (Investigator)

  1/11/10 → 31/01/15

  Project: Research

  • Biochemical Model 100%
  • NodC 100%
  • Processive 100%
  • Chitin Synthase 100%
  • Chitin Synthesis 100%

• Control of Noise in Eukaryotic Gene Expression (Senior Research Fellowship)

  Chubb, J. (Investigator) & Weijer, K. (Investigator)

  1/11/10 → 31/10/15

  Project: Research

  • Dynamics 100%
  • Dictyostelium 58%
  • Transcription 54%
  • Nuclear Organization 50%
  • RNA Dynamics 50%

• The Role of O-GlcNAc in Bacterial Signal Transduction and Virulence (Return to Europe Fellowship)

  Rao, F. (Investigator) & van Aalten, D. (Investigator)

  1/11/10 → 31/10/12

  Project: Research

• Research into RNA Structure and Function

  Lilley, D. (Investigator)

  Royal Society of Edinburgh

  1/10/10 → 30/09/12

  Project: Research

• EPIGENESYS: Epigenetics Towards Systems Biology (joint with 15 other partners)

  Harrison, P. (Investigator) & Lamond, A. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/10/10 → 31/03/16

  Project: Research

  • Chromatin 100%
  • Chromatin Conformation 50%
  • Edmonton 50%
  • Canada 50%
  • MMS22L 50%

• The Translation of Quantitative Proteomics Applied to Human Disease (Dr Kathryn Kirkwood)

  Cantrell, D. (Investigator), Kirkwood, K. (Investigator), Lambert, J. (Investigator), Lamond, A. (Investigator) & Marshall, S. (Investigator)

  6/09/10 → 5/08/14

  Project: Research

• Combined Genetic and Biochemical Approaches to Uncover and Characterize Redundant Factors Involved in Late Stages of Recombinational Repair

  Gartner, A. (Investigator) & Lamond, A. (Investigator)

  1/08/10 → 30/04/17

  Project: Research

  • Caenorhabditis Elegans 100%
  • DNA Repair 30%
  • DNA Damage 25%
  • Programmed Cell Death 24%
  • Germ Cell 22%

• Aref#d: 21363. RNA Folding as a Mediator of Stress Response in Plants (Joint with Pennsylvania University)

  Lilley, D. (Investigator)

  1/08/10 → 31/07/13

  Project: Research

• Aref#d: 21557. Isolation of Pooled Selected Gene Segments for Allele Discovery by Next Generation Sequencing (Tools and Resources Development Fund)

  Flavell, A. (Investigator), Hasan-Syed, N. (Investigator) & Swedlow, J. (Investigator)

  1/07/10 → 31/12/12

  Project: Research

  • Data Management 100%
  • Biological Microscopy 100%
  • Flexible Model 100%
  • Experimental Biology 100%
  • Acquisition Management 100%

• Intuitive Large Scale Image Processing for Biologists (Joint with University of Edinburgh)

  Swedlow, J. (Investigator)

  1/07/10 → 31/12/12

  Project: Research

• Aref#d: 22086. Role of Fibroblast-Growth Factor Signalling in Epithelial Remodelling

  Muller, A. (Investigator)

  Medical Research Council

  1/05/10 → 31/10/13

  Project: Research

• Aref#d: 22158. Regulation of Myosin II Filament Assembly and Stabilisation, Localisation and Cortical Anchoring (Research Career Development Fellowship)

  Griffis, E. (Investigator) & Lamond, A. (Investigator)

  1/05/10 → 30/04/15

  Project: Research

• Aref#d: 21680. The Flagellum and Cell Fate Differentiation

  Stanley-Wall, N. (Investigator) & Swedlow, J. (Investigator)

  12/04/10 → 11/04/13

  Project: Research

  • Bacillus subtilis 100%
  • Bacillus Subtilis (B. subtilis) 86%
  • Biofilm 59%
  • Degu 52%
  • Octodon Degus 52%

• Aref#d: 22289. Proteomic, Functional and Systems Analysis of Mitotic Chromosome Organisation and its Interdependence with DNA Replication

  Blow, J. (Investigator) & Swedlow, J. (Investigator)

  1/04/10 → 31/07/14

  Project: Research

• Aref#d: 21938. Establishing and Exploiting C Elegans as a Simple Invertebrate Model for Parkinson's Disease

  Gartner, A. (Investigator)

  1/03/10 → 31/01/14

  Project: Research

• Aref#d: 22161. Regulation of Cell Size in Multicellular Organisms (Research Career Development Fellowship)

  Bjorklund, M. (Investigator) & Hardie, G. (Investigator)

  1/02/10 → 30/04/15

  Project: Research

  • Modified Ribosomes 100%
  • NQO2 100%
  • Ribosome Profiling 100%
  • Cell Size 100%
  • 3′-untranslated Region (3′-UTR) 100%

• Aref#d: 21738. Systems Biology Profiling of SUMO Substrate Proteome in Signalling Pathways (Sir Henry Wellcome Postdoctoral Fellowship - Dr Ivan Matic)

  Lamond, A. (Investigator) & Matic, I. (Investigator)

  1/02/10 → 30/06/14

  Project: Research

  • ADPr 100%
  • Polymerase Activity 100%
  • Small Ubiquitin-like Modifier 100%
  • Proteome-wide 100%
  • Adenosine Diphosphate Ribose 100%

• Aref#d: 22417. NUCLEOSOME 4D Nucleosome Structure and Function across Biological Scales and Biological Function (EC FP7 People, Marie Curie Initial Training Networks)

  Owen-Hughes, T. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/09 → 31/10/13

  Project: Research

• Aref#d: 21151. Molecular Mechanisms of Assembly, Regulation and Substrate Recognition of the Heterotrimeric LKB1 Tumour Suppressor

  Alessi, D. (Investigator) & van Aalten, D. (Investigator)

  1/11/09 → 31/10/12

  Project: Research

• Aref#d: 21559. Molecular Mechanisms of Fungal Cell Wall Assembly (Programme Grant)

  van Aalten, D. (Investigator)

  Medical Research Council

  1/11/09 → 31/10/14

  Project: Research

  • O-linked N-acetylglucosamine (O-GlcNAc) 100%
  • Enzyme 81%
  • O-GlcNAcase 80%
  • Transferase 74%
  • N-Acetylglucosamine 54%

• Aref#d: 21240. Myc-Induced mRNA Cap Methylation (PhD Studentship)

  Cowling, V. (Investigator)

  1/10/09 → 30/09/13

  Project: Research

• Aref#d: 21477. The Adenomatous Polyposis Protein in Colorectal Cancer; from Biochemistry to Tissue Architecture (Programme Grant)

  Nathke, I. (Investigator)

  1/10/09 → 30/09/15

  Project: Research

  • Adenomatous Polyposis Coli 100%
  • Interkinetic nuclear Migration 50%
  • Proteomics 50%
  • Catenin 50%
  • Intestinal Organoids 50%

• Aref#d: 21329. The Electron Microscope Data Bank EMDB (Joint with European Bioinformatics Institute)

  Swedlow, J. (Investigator)

  1/10/09 → 30/09/12

  Project: Research

• Aref#d: 22363. Molecular and Cellular Biology PhD Programme (4 Year PhD Studentship: Colin Hammond)

  Crocker, P. (Investigator) & Owen-Hughes, T. (Investigator)

  7/09/09 → 6/09/13

  Project: Research

• Clinical PhD Programme: Katherine Walker

  Cantrell, D. (Investigator), Hay, R. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)

  7/09/09 → 6/09/12

  Project: Research