Molecular Cell and Developmental Biology

Projects

Projects per year 2004 2010 2012 2013 2014 2015 2016 2017 2018 2031

• 32 Active
• 59 Not started
• 230 Finished

Projects per year

Search results

• Active

  Post Transcriptional Regulation Of Oscillatory Clock Gene Expression During Somitogenesis

  Dale, K. (Investigator) & Murray, P. (Investigator)

  Medical Research Council

  1/04/24 → 31/03/27

  Project: Research

• Deciphering The Role Of Adipose Tissue In Common Metabolic Disease Via Adipose Tissue Proteomics - Joint with Kings College, London

  Lamond, A. (Investigator)

  Medical Research Council

  1/04/24 → 31/03/27

  Project: Research

• Understanding Error Correction For Chromosome Bi-orientation Using In Vitro Reconstruction

  Tanaka, T. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/24 → 31/03/27

  Project: Research

• Unlocking The Alternative Splicing Code

  Lamond, A. (Investigator) & Schweikert, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/03/24 → 28/02/25

  Project: Research

• New Players In The Targeted Degradation Of The PML-RARA Oncogene By Arsenic

  Hay, R. (Investigator)

  1/01/24 → 31/12/28

  Project: Research

  • Target Molecule 100%
  • Degrader 100%
  • Ubiquitination 100%
  • Lysine 50%
  • Ubiquitin 50%

• Modelling TDP-43-induced aging in Drosophila melanogaster

  McGurk, L. (Investigator)

  1/12/23 → 31/05/25

  Project: Research

• Blocking TDP-43 From Accumulating In The Cytoplasm As A Therapeutic Strategy For ALS

  McGurk, L. (Investigator)

  1/12/23 → 30/11/25

  Project: Research

• Interrogating Tankyrase-mediated Control of Neuronal Degeneration in Frontotemporal Dementia (Dementia Research Leader Fellowship) (Outline) & Full

  Alessi, D. (Investigator), Ashford, M. (Investigator), Davies, P. (Investigator), McGurk, L. (Investigator) & Storey, K. (Investigator)

  Alzheimer's Society

  2/10/23 → 1/10/28

  Project: Research

• Advancement of Sperm-targeting Contraceptive Agents

  Barratt, C. (Investigator), Gilbert, I. (Investigator), Martins Da Silva, S. (Investigator), Read, K. (Investigator), Swedlow, J. (Investigator) & Wyllie, S. (Investigator)

  Bill and Melinda Gates Foundation

  5/07/23 → 4/07/26

  Project: Research

• Mechanisms Of Selective Protein Secretion: Towards Therapeutic Interventions

  Miller, L. (Investigator)

  1/07/23 → 30/06/31

  Project: Research

• Characterising Splice Site Modulation Approaches For Huntington's Disease Therapeutics

  Lamond, A. (Investigator)

  1/06/23 → 31/05/25

  Project: Research

• Harnessing the splicing code for targeted control of gene expression (UNLEASH)

  Gray, D. (Investigator) & Lamond, A. (Investigator)

  1/06/23 → 31/05/29

  Project: Research

  • Induced Stem Cell 100%
  • Induced Pluripotent Stem Cells (iPSCs) 100%
  • Human-induced 100%
  • Embryonic Stem Cells 100%
  • Proteomic Comparison 100%

• Expanding the Chemical Range of RNA-mediated Catalysis: Structure and Mechanism

  Lilley, D. (Investigator)

  Engineering and Physical Sciences Research Council

  1/04/23 → 31/03/26

  Project: Research

  • Catalytic Mechanism 100%
  • Riboswitch 100%
  • Ribozyme 100%
  • RNA 62%
  • Pseudoknot 57%

• Investigating The Functions and Regulation of Non-Proline Directed CDK1 Phosphorylation

  Ly, T. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/23 → 31/03/26

  Project: Research

• Early-Stage Embryo as an Active Self-Tuning Soft Material (Lead: UoD other instn: University of Oxford, University College London)

  Sknepnek, R. (Investigator) & Weijer, K. (Investigator)

  Engineering and Physical Sciences Research Council

  1/04/22 → 31/03/25

  Project: Research

  • Vertex Model 100%
  • Viscoelastic Response 66%
  • Normal Mode Analysis 66%
  • Linear Viscoelasticity 66%
  • Rheological Behavior 66%

• Protein Correlation Profiling Analysis Of The Nipah Virus-Host Interface (Fellowship)

  Harrison, A. (Investigator) & Lamond, A. (Investigator)

  1/02/22 → 31/01/25

  Project: Research

• Establishment of Cryo-EM Screening Facility At University Of Dundee (Equipment Grant)

  Kulathu, Y. (Investigator), Labib, K. (Investigator), Masson, G. (Investigator), Moraga Gonzalez, I. (Investigator), Murray, D. (Investigator), Owen-Hughes, T. (Investigator), Stanley-Wall, N. (Investigator) & Wyatt, P. (Investigator)

  1/12/21 → 31/12/26

  Project: Research

  • Ligase 100%
  • E3 Ligase 83%
  • Ubiquitination 58%
  • Degrader 55%
  • Cryo-electron Microscope 41%

• Dissection the coupling of cell polarity with the stem cell cycle by chemical genetics

  Januschke, J. (Investigator) & Murray, P. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/12/21 → 30/11/24

  Project: Research

  • Drosophilidae 100%
  • Video Project 33%
  • Long History 33%
  • Tissue Rupture 33%
  • Nervous System 33%

• mRNA Cap Regulation of Gene Express, Cell Function and Fate (Investigator Award)

  Cowling, V. (Investigator)

  1/11/21 → 31/10/26

  Project: Research

  • Cap Formation 100%
  • MRNA Cap 100%
  • Cap Gene 100%
  • Gene Expression 100%
  • T Cell Activation 100%

• Chemical and Genetic Validation of Aspergillus Fumigatus Cell Wall Targets

  van Aalten, D. (Investigator)

  Medical Research Council

  1/06/21 → 31/05/26

  Project: Research

  • Cell Wall 100%
  • Aspergillus fumigatus 83%
  • Aspergillus Fumigatus 71%
  • Fumigatus 48%
  • Glucose-6-phosphatase (G6Pase) 40%

• Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus (Joint with the University of Oslo)

  Lamond, A. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/05/21 → 30/04/25

  Project: Research

  • Induced Stem Cell 100%
  • Induced Pluripotent Stem Cells (iPSCs) 100%
  • Human-induced 100%
  • Embryonic Stem Cells 100%
  • Proteomic Comparison 100%

• Dynamic Regulation of Chromatin Loops by Cohesins and CTCF in Real Time: Physiology and Pathology

  Tanaka, T. (Investigator)

  Medical Research Council

  1/01/21 → 31/12/24

  Project: Research

• Kinetochore-Microtubule Interactions: Steps Towards Bi-Orientation (Investigator Award)

  Tanaka, T. (Investigator)

  1/12/20 → 30/11/25

  Project: Research

  • Kinetochore 100%
  • Error Correction 99%
  • Biorientation 87%
  • Microtubule 76%
  • Microtubules 41%

• Machine Learning Methods to Re-Annotate Histone Modifications with Locus-specific Functional Classification (Future Leaders Fellowship)

  Owen-Hughes, T. (Investigator) & Schweikert, G. (Investigator)

  Medical Research Council

  1/11/20 → 31/10/25

  Project: Research

  • Biological Research 100%
  • Epigenetic Modification 100%
  • Epigenetics 100%
  • Machine Learning 100%
  • Individual-specific 100%

• Multi-Scale Analysis of 4D Nucleome Structure and Function by Comprehensive Multimodal Data Integration (Joint with Carnegie Mellon University, USA)

  Swedlow, J. (Investigator)

  National Institutes of Health

  22/09/20 → 30/06/25

  Project: Research

• Establishing the Basis for Selectivity in the SUMO Spray (Investigator Award)

  Hay, R. (Investigator)

  1/02/20 → 31/01/25

  Project: Research

  • Ubiquitin 100%
  • RNF4 42%
  • Ubiquitination 40%
  • Ubiquitin-like 39%
  • Small Ubiquitin-like Modifier 36%

• Investigation of Mechanics of Gastrulation Using New Transgenic Lines

  Weijer, K. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/01/20 → 31/12/24

  Project: Research

  • Gastrulation 100%
  • Chick Embryo 82%
  • Chick 72%
  • Vertebrates 65%
  • Cell Behavior 44%

• Aberrant DNA Methylation and its Impact in Blood Cancer Development (Career Development Fellowship)

  Owen-Hughes, T. (Investigator) & Rasmussen, K. (Investigator)

  1/06/19 → 31/05/25

  Project: Research

  • Hematopoiesis 100%
  • Non-catalytic 100%
  • Protein Complex 100%
  • Ten-eleven Translocation 1 (TET1) 100%
  • TET Proteins 100%

• Structure and Function of Chromatin Remodelling ATPases and their Dysfunction in Human Disease

  Owen-Hughes, T. (Investigator) & Sundaramoorthy, R. (Investigator)

  Medical Research Council

  1/04/19 → 31/03/25

  Project: Research

  • Histone 100%
  • Enzyme 90%
  • Chromatin Remodeling 85%
  • Isoform 80%
  • Chromatin 70%

• Structural Mechanics in Cellular Substructure Formation (Sir Henry Dale Fellowship)

  Murray, D. (Investigator) & Storey, K. (Investigator)

  1/11/18 → 30/04/25

  Project: Research

  • Phosphoinositide 100%
  • Phosphoinositides 70%
  • PI(3,5)P2 40%
  • PIKfyve 40%
  • Drosophilidae 40%

• Industrial Collaborative Awards in Science and Engineering (iCASE) Studentships for the University of Dundee

  Hunter, B. (Investigator) & MacKintosh, C. (Investigator)

  Medical Research Council

  3/09/18 → 30/09/25

  Project: Research

  • Gram-negative Bacteria 100%
  • Gram Negative Bacterium 80%
  • Antibiotics 66%
  • Drug Development 57%
  • Gram-negative 53%

• Training the Next Generation of Scientists in Quantitative and Interdisciplinary Approaches to Biomedical Science (Doctoral Training Partnership)

  Hunter, B. (Investigator) & MacKintosh, C. (Investigator)

  Medical Research Council

  11/11/16 → 30/09/25

  Project: Research

  • Ca2+ 100%
  • Knock-in Mouse Model 100%
  • Ion Channels 90%
  • Binding Site 86%
  • Cation Permeation 83%