Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where MRC PPU is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Prophylactic Approaches To Treating Intestinal Damage In Coeliac Disease - Joint with University of Sheffield
Swamy, M. (Investigator)
1/09/24 → 31/08/27
Project: Research
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Mutational screen of GBA1, PARKIN and LRRK2
Alessi, D. (Investigator), Muqit, M. (Investigator) & Sammler, E. (Investigator)
1/08/24 → 31/07/26
Project: Research
Research output
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Artificial targeting of autophagy components to mitochondria reveals both conventional and unconventional mitophagy pathways
Lorentzen, K., Prescott, A. & Ganley, I. (Lead / Corresponding author), 2025, In: Autophagy. 21, 2, p. 315-337 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)32 Downloads (Pure) -
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Sinclair, L. V. (Lead / Corresponding author), Youdale, T., Spinelli, L., Gakovic, M., Langlands, A. J., Pathak, S., Howden, A. J. M., Ganley, I. G. & Cantrell, D. A. (Lead / Corresponding author), 27 Feb 2025, In: Nature Immunology. 26, p. 429-443 32 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Diseases caused by altered specificity of a protein kinase for its allosteric activators
Cohen, P. (Lead / Corresponding author) & Snelling, T. (Lead / Corresponding author), 2 Jan 2025, In: Trends in Biochemical Sciences. 50, 1, p. 61-70 10 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Downloads (Pure)
Datasets
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Bustos et al Dev Cell 2020 Source Data
Findlay, G. (Creator) & Bustos, F. (Creator), Mendeley Data, 23 Oct 2020
Dataset
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UFC1-UFM1 conjugate
Kulathu, Y. (Supervisor), Research Collaboratory for Structural Bioinformatics Protein Data Bank, 2023
DOI: 10.2210/pdb8BZR/pdb
Dataset
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UFL1/DDRG1 bound to UFC1
Kulathu, Y. (Creator), University of Dundee, 2023
DOI: 10.2210/pdb8C0D/pdb
Dataset
Prizes
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51st Croom Medal and Lectureship
Mehta, A. (Recipient), Jan 2025
Prize: Prize (including medals and awards)
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Brian Cox engaged researcher award
Williams, T. (Recipient), 2022
Prize: Prize (including medals and awards)
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Brian Cox engaged researcher commendation
Williams, T. (Recipient), 2021
Prize: Prize (including medals and awards)
Activities
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Scientific Reports (Journal)
Virdee, S. (Editorial board member)
2924Activity: Publication peer-review and editorial work types › Publication peer-review
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Maryfield Family Food and Fun Easter 2025
Floyd, A. (Organiser), Brewer, A. (Participant), Cordova Perez, A. (Participant), Perez i Rafols, A. (Participant) & Edgar, R. (Participant)
3 Apr 2025 → 10 Apr 2025Activity: Other activity types › Public engagement and outreach - festival/exhibition
Press/Media
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LRRK2 Investigative Therapeutic Exchange (LITE) project
21/10/24
1 Media contribution
Press/Media: Other
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STV news article about Parkinson's research, public engagement and clinical trials in Dundee
6/02/24
1 Media contribution
Press/Media: Research
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Student theses
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Activation of the Parkinson's disease kinase LRRK2 by Rab GTPases
Purlyte, E. (Author), Alessi, D. (Supervisor), 2021Student thesis: Doctoral Thesis › Doctor of Philosophy
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Advancing understanding of endogenous PINK1-Parkin signalling linked to Parkinson’s disease
Balk, K. R. (Author), Muqit, M. (Supervisor) & Alessi, D. (Supervisor), 2019Student thesis: Doctoral Thesis › Doctor of Philosophy
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Analysis of PINK1-Parkin-dependent signalling in neurons
Antico, O. (Author), Muqit, M. (Supervisor) & Alessi, D. (Supervisor), 2022Student thesis: Doctoral Thesis › Doctor of Philosophy
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