Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where MRC PPU is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Prophylactic Approaches To Treating Intestinal Damage In Coeliac Disease - Joint with University of Sheffield
Swamy, M. (Investigator)
1/09/24 → 31/08/27
Project: Research
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Mutational screen of GBA1, PARKIN and LRRK2
Alessi, D. (Investigator), Muqit, M. (Investigator) & Sammler, E. (Investigator)
1/08/24 → 31/07/26
Project: Research
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Sugar Ubiquitylation, A New Quality Control Mechanism For The Recognition And Elimination Of Misfolded Macromolecules
Cohen, P. (Investigator)
Biotechnology and Biological Sciences Research Council
1/06/24 → 30/11/25
Project: Research
Research output
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Academic neurology in the UK: a plea to turn away from the precipice
Devine, H. (Lead / Corresponding author), Jabbari, E., Scott, J., Mehta, A., Dobson, R. & Mead, S., 21 May 2024, (E-pub ahead of print) In: Brain.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile30 Downloads (Pure) -
A CDK1 phosphorylation site on Drosophila PAR-3 regulates neuroblast polarisation and sensory organ formation
Loyer, N., Hogg, E. K. J., Shaw, H. G., Pasztor, A., Murray, D. H., Findlay, G. M. & Januschke, J. (Lead / Corresponding author), 1 Jul 2024, In: eLife. 13, e97902.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Downloads (Pure) -
Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans
Lenka, D. R., Dahe, S. V., Antico, O., Sahoo, P., Prescott, A. R., Muqit, M. M. K. & Kumar, A. (Lead / Corresponding author), 2 Sept 2024, (E-pub ahead of print) In: eLife. 13, 31 p., RP96699.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure)
Datasets
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Bustos et al Dev Cell 2020 Source Data
Findlay, G. (Creator) & Bustos, F. (Creator), Mendeley Data, 23 Oct 2020
Dataset
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Functional 3D architecture in an intrinsically disordered E3 ligase domain facilitates ubiquitin transfer (dataset)
Murphy, P. (Creator), Xu, Y. (Creator), Rouse, S. L. (Creator), Jaffray, E. G. (Creator), Plechanovová, A. (Creator), Matthews, S. J. (Creator), Penedo, C. (Creator) & Hay, R. T. (Creator), University of St Andrews, 2020
DOI: 10.17630/5d766785-60c8-4dbe-99ec-926e2fa33798, https://research-portal.st-andrews.ac.uk/en/datasets/functional-3d-architecture-in-an-intrinsically-disordered-e3-liga
Dataset
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Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity
De Cesare, V. (Creator), Zenodo, 18 Dec 2023
DOI: 10.5281/zenodo.10402851, https://zenodo.org/records/10402851
Dataset
Prizes
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Brian Cox engaged researcher award
Williams, T. (Recipient), 2022
Prize: Prize (including medals and awards)
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Brian Cox engaged researcher commendation
Williams, T. (Recipient), 2021
Prize: Prize (including medals and awards)
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British Society for Cell Biology (BSCB) Postdoctoral Researcher Medal
Williams, T. (Recipient), 2023
Prize: Prize (including medals and awards)
Activities
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Auchterhouse Primary School
Toth, R. (Visiting researcher)
5 Feb 2024Activity: Visiting an external institution types › Visiting an external academic institution
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1st UK Workshop on Quantum Technologies for Life Sciences and Health
Madsen, R. (Chair)
18 Jun 2024 → 19 Jun 2024Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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UK Committee on Research Integrity (UKCORI) (External organisation)
Madsen, R. (Member)
2024Activity: Membership types › Membership of committee
Press/Media
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STV news article about Parkinson's research, public engagement and clinical trials in Dundee
6/02/24
1 Media contribution
Press/Media: Research
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Parkinson's disease hope: 'This is a very exciting time'
15/09/23
1 Media contribution
Press/Media: Research
Student theses
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Activation of the Parkinson's disease kinase LRRK2 by Rab GTPases
Purlyte, E. (Author), Alessi, D. (Supervisor), 2021Student thesis: Doctoral Thesis › Doctor of Philosophy
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Advancing understanding of endogenous PINK1-Parkin signalling linked to Parkinson’s disease
Balk, K. R. (Author), Muqit, M. (Supervisor) & Alessi, D. (Supervisor), 2019Student thesis: Doctoral Thesis › Doctor of Philosophy
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Analysis of PINK1-Parkin-dependent signalling in neurons
Antico, O. (Author), Muqit, M. (Supervisor) & Alessi, D. (Supervisor), 2022Student thesis: Doctoral Thesis › Doctor of Philosophy
File