Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where MRC PPU is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Prophylactic Approaches To Treating Intestinal Damage In Coeliac Disease - Joint with University of Sheffield
Swamy, M. (Investigator)
1/09/24 → 31/08/27
Project: Research
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Mutational screen of GBA1, PARKIN and LRRK2
Alessi, D. (Investigator), Muqit, M. (Investigator) & Sammler, E. (Investigator)
1/08/24 → 31/07/26
Project: Research
Research output
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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores
Allan, L. A., Corno, A., Valverde, J., Toth, R., Ly, T. & Saurin, A. T. (Lead / Corresponding author), 29 Mar 2025, (E-pub ahead of print) In: Nature Communications. 16, 15 p., 3069.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)29 Downloads (Pure) -
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase
Fiesel, F. C., Bustillos, B. A., Watzlawik, J. O., Chen, C. X. Q., Berryer, M. H., Zhang, J., Boneski, P. K., Hayes, C. S., Bredenberg, J. M., Deneault, E., You, Z., Abdien, N., Aprahamian, N., Goldsmith, T. M., Baninameh, Z., Cocker, L. T., Zhang, H., Goldberg, M. S., Fon, E. A. & Trempe, J. F. & 3 others, , 18 Jul 2025, (E-pub ahead of print) In: Autophagy. 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
ADDENDUM: Disruption of the striated muscle glycogen-targeting subunit of protein phosphatase 1: influence of the genetic background (Journal of Molecular Endocrinology, (2008), 40, 2, (47–59), 10.1677/JME-07-0120)
Paterson, J., Kelsall, I. R., Cohen, P. T. W. & Näthke, I. (Lead / Corresponding author), Apr 2025, In: Journal of Molecular Endocrinology. 74, 3, a070120.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile20 Downloads (Pure)
Datasets
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Bustos et al Dev Cell 2020 Source Data
Findlay, G. (Creator) & Bustos, F. (Creator), Mendeley Data, 23 Oct 2020
Dataset
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UFL1/DDRG1 bound to UFC1
Kulathu, Y. (Creator), University of Dundee, 2023
DOI: 10.2210/pdb8C0D/pdb
Dataset
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UFC1-UFM1 conjugate
Kulathu, Y. (Supervisor), Research Collaboratory for Structural Bioinformatics Protein Data Bank, 2023
DOI: 10.2210/pdb8BZR/pdb
Dataset
Prizes
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51st Croom Medal and Lectureship
Mehta, A. (Recipient), Jan 2025
Prize: Prize (including medals and awards)
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Brian Cox engaged researcher award
Williams, T. (Recipient), 2022
Prize: Prize (including medals and awards)
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Brian Cox engaged researcher commendation
Williams, T. (Recipient), 2021
Prize: Prize (including medals and awards)
Activities
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Medical Research Scotland “Meet The Researcher Showcase”
-, N. (Presenter)
12 Jun 2025Activity: Other activity types › Public engagement and outreach - festival/exhibition
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Coffee and conversation on Coeliac in St. Andrews
Swamy, M. (Speaker) & Borichevsky, G. (Speaker)
Apr 2025Activity: Other activity types › Other
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Life Music exhibition and drop-in art workshop
Aitken, J. (Presenter), Cameron, A. (Organiser), Swatek, K. (Participant), Siddiqui, R. (Participant), Vats, A. (Participant), Rathod, S. (Participant), Prescott, A. (Contributor) & Sknepnek, R. (Contributor)
28 Sept 2025Activity: Other activity types › Public engagement and outreach - festival/exhibition
Press/Media
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LRRK2 Investigative Therapeutic Exchange (LITE) project
21/10/24
1 Media contribution
Press/Media: Other
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STV news article about Parkinson's research, public engagement and clinical trials in Dundee
6/02/24
1 Media contribution
Press/Media: Research
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Student theses
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Activation of the Parkinson's disease kinase LRRK2 by Rab GTPases
Purlyte, E. (Author), Alessi, D. (Supervisor), 2021Student thesis: Doctoral Thesis › Doctor of Philosophy
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Advancing understanding of endogenous PINK1-Parkin signalling linked to Parkinson’s disease
Balk, K. R. (Author), Muqit, M. (Supervisor) & Alessi, D. (Supervisor), 2019Student thesis: Doctoral Thesis › Doctor of Philosophy
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Analysis of PINK1-Parkin-dependent signalling in neurons
Antico, O. (Author), Muqit, M. (Supervisor) & Alessi, D. (Supervisor), 2022Student thesis: Doctoral Thesis › Doctor of Philosophy
File