MRC PPU

Projects

Projects per year 2008 2026

• 17 Not started
• 32 Active
• 97 Finished

Projects per year

Search results

• Active

  Mouse Cell Line Characterisation (other inst: Rutgers University)

  Alessi, D.

  4/01/21 → 3/01/23

  Project: Research

• Determining the ligase and DUB landscape of mitochondrial and alpha-synuclein turnover

  Ganley, I., Sapkota, G. & Virdee, S.

  1/12/20 → 30/11/22

  Project: Research

• MRC PPU Covid Research

  Alessi, D. & Davies, P.

  Medical Research Council

  18/10/20 → 17/07/21

  Project: Research

• ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components

  Alessi, D. & Muqit, M.

  1/10/20 → 30/09/23

  Project: Research

• Defining Mechanisms of Protein Ufmylation

  Kulathu, Y.

  Biotechnology and Biological Sciences Research Council

  1/09/20 → 31/08/23

  Project: Research

• RNF12 E3 Ubiquitin Ligase Substrate Degraders as a Therapeutic Strategy in Tonne-Kalscheuer Syndrome (TOKAS)

  Bustos, F. & Findlay, G.

  1/03/20 → 28/02/22

  Project: Research

• DNA Interstrand Crosslink Repair and Chromatin Remodelling (ICL CHROM)

  Rouse, J.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/02/20 → 23/04/22

  Project: Research

• Characterization of pT73 Rab10 Protein from XProChem and Supply of pRab8A and pRab10 Protein to Abcam for Assay Development

  Alessi, D. & Davies, P.

  1/01/20 → 14/08/21

  Project: Research

• Validation of antibodies to ubiquitin-conjugated proteins for mitophagy readouts

  Muqit, M.

  11/12/19 → 1/12/22

  Project: Research

• Short Linear Interaction Motifs as Specificity Determinants in the Ubiquitin System - Discovery, Mechanisms and Therapuetic Opportunities (UBIMOTIF)

  Kulathu, Y.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/12/19 → 30/11/23

  Project: Research

• C5aR a Novel Immunomodulator of Metabolic Signalling and Energy Metabolism in Skeletal Muscle

  Ganley, I., Hundal, H., Lipina, C. & McCrimmon, R.

  Diabetes UK

  4/11/19 → 25/02/23

  Project: Research

• Genome-wide and chemical screens to uncover novel upstream regulators of the LRRK2 signaling network

  Alessi, D.

  1/08/19 → 14/01/23

  Project: Research

• Antigen and Validation for New pS228 PINK1 and pT257 PINK1 Antibodies at Abcam

  Muqit, M.

  1/03/19 → 7/02/22

  Project: Research

• Processing of Branched DNA Molecules During Cytokinesis, Uncovering New Mechanisms of Genome Maintenance

  Gartner, A., Lilley, D. & Rouse, J.

  Biotechnology and Biological Sciences Research Council

  1/12/18 → 30/11/21

  Project: Research

• Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders

  Muqit, M. & Sapkota, G.

  10/09/18 → 9/09/21

  Project: Research

• Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

  Ciulli, A. & Sapkota, G.

  3/09/18 → 2/09/22

  Project: Research

• Regulation of the Parkinson's kinase LRRK2

  Alessi, D.

  Parkinson's UK

  3/09/18 → 2/09/21

  Project: Research

• Functions and Applications of a Novel Pluripotency Signalling Pathway (Sir Henry Dale Fellowship)

  Findlay, G.

  Wellcome Trust

  1/09/18 → 31/08/23

  Project: Research

• Expanding the Druggable Proteome of Innate Immune Cells - Towards Synthetic Immune Regulation (Fellowship - with Scripps Research Institute)

  Cohen, P. & Kavanagh, M.

  Wellcome Trust

  1/07/18 → 30/06/22

  Project: Research

• Elucidation of Mechanisms that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases

  Arthur, S. & Cohen, P.

  Medical Research Council

  1/04/18 → 31/03/23

  Project: Research

• MRC QQR

  Alessi, D., Davies, P., Ganley, I., Kulathu, Y., Labib, K., Rouse, J., Rousseau, A., Sapkota, G., Virdee, S. & Walden, H.

  Medical Research Council

  1/04/18 → 31/03/23

  Project: Research

• The Molecular Mechanisms by which TRAF6 Regulates the Immune System

  Cohen, P.

  Wellcome Trust

  1/04/18 → 31/03/23

  Project: Research

• Novel Genome Integrity Pathways that Regulate DNA Replication Termination in Metazoa

  Labib, K.

  Cancer Research UK

  1/03/18 → 28/02/23

  Project: Research

• Regulation and Function of Protein FUBIylation (Lister Institute Research Prize 2017)

  Kulathu, Y.

  Lister Institute of Preventive Medicine

  1/10/17 → 30/09/22

  Project: Research

• Molecular Determinants of Intraepithelial Lymphocyte Function in Intestinal Infection (Sir Henry Dale Fellowship)

  Swamy, M.

  Wellcome Trust

  1/09/17 → 31/08/22

  Project: Research

• Activity Based Proteomics of E3 Ligases

  Virdee, S.

  Biotechnology and Biological Sciences Research Council

  1/07/17 → 30/06/21

  Project: Research

• Molecular Mechanisms of DNA Replication Termination

  Deegan, T.

  Wellcome Trust

  1/05/17 → 1/11/21

  Project: Research

• Regulation of DNA Interstrand Crosslink Repaid by Ubiquitin (ICLUB) (ERC Consolidator)

  Walden, H.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/09/16 → 31/08/21

  Project: Research

• Rab Detection Initiative (Joint with Stanford School of Medicine, Max Plank Institute, Neuroscience Research Australia and Parkinsons Institute California)

  Alessi, D. & Davies, P.

  1/08/16 → 31/07/21

  Project: Research

• Regulation of Lymphocyte Biology by Ubiquitin and Ubiquitin like Modifiers RELYUBL (Starting Grant)

  Kulathu, Y.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/06/16 → 31/12/21

  Project: Research

• Young Investigator Programme

  Kulathu, Y.

  European Molecular Biology Organization

  1/01/16 → 31/12/26

  Project: Research

• Biochemical Analysis of the PINK-1 Parkin Signalling Pathway in Parkinson's Disease (Senior Clinical Fellowship)

  Muqit, M.

  Wellcome Trust

  1/07/13 → 31/12/23

  Project: Research

• Not started

  Differential LRRK2 Dependent Rab Phosphorylation Signatures in Peripheral Blood and Urine in Idiopathic and Monogenetic PD

  Alessi, D. & Sammler, E.

  1/06/21 → 31/05/22

  Project: Research

• Dundee Training Programme in Integrated Molecular, Cellular and Translational Biology

  Arthur, S., Coulthurst, S., Hay, R. & Muqit, M.

  Project: Research

• Analysis of the Role of Phopho-Ubiquitin in Parkinsons Disease Signalling (Enhancement Grant)

  Muqit, M.

  Project: Research

• MRC Public Engagement 2014-2015

  Alessi, D.

  Project: Research

• MRC Festival Funding

  Davies, P.

  Project: Research

• Targeting E3 ubiquitin lifases with sall molecules (iCASE) Student - Thomas Webb

  Ciulli, A. & Virdee, S.

  Project: Research

• An Optically Clear Prototype for the Culture and Detection of Circulating Tumour Cells (joint with Heriot-Watt University)

  Katz, E.

  Project: Research

• Aref#d: 22085. Scottish Institute for Cell Signalling (SCILLS) Strategic Research Development Grant

  Cohen, P.

  Project: Research

• Development of better approaches to study PINK1 structure (joint application with University Medical Centre Goettingen and University of Frankfurt)

  Muqit, M.

  Project: Research

• WORLD CLASS LABS FUNDING OFFER 2020/21

  Davies, P.

  Project: Research

• Aref#d: 12419. The establishment of a Post-Genomics and Molecular Interactions Centre at the University of Dundee (Joint Infrastructure Fund - supplement)

  Cohen, P., Downes, P., Fairlamb, A., Ferguson, M., Hunter, B., Lamond, A., Lilley, D., Norman, D., Watts, C. & Williams, J.

  Project: Research

• A Simplified System to Study Regulation of the WNK Signalling Pathway (Long Term Fellowship)

  Daubner, G.

  Project: Research

• Faithful Epigenetic Inheritance And Germline Integrity In C Elegans

  Saredi, G.

  Project: Research

• Summer Studentship (2019)

  Muqit, M.

  Project: Research

• PhD Placement Grant

  Alessi, D. & Kulathu, Y.

  Project: Research

• Supplement Award: Development of Tools for PINK1 Pathways Analysis In Parkinson's Disease

  Muqit, M.

  Project: Research

• Aref#d: 9354. The establishment of a Post-Genomics and Molecular Interactions Centre at the University of Dundee (Joint Infrastructure Fund)

  Cohen, P., Downes, P., Fairlamb, A., Ferguson, M., Hunter, B., Lamond, A., Lilley, D., Norman, D., Watts, C. & Williams, J.

  Project: Research

• Finished

  World Class Labs

  Alessi, D. & Davies, P.

  Medical Research Council

  1/10/20 → 31/03/21

  Project: Research