MRC PPU

School of Life Sciences

15 Not started
36 Active
115 Finished

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Supplement Award: Development of Tools for PINK1 Pathways Analysis In Parkinson's Disease
Muqit, M.
1/06/21 → 31/05/22
Project: Research
World Class Labs Capital Award 21/22
Alessi, D. & Davies, P.
Medical Research Council
1/04/21 → 31/03/22
Project: Research
World Class Labs Capital Funding Offer 2021/22
Alessi, D. & Davies, P.
Medical Research Council
1/04/21 → 31/03/22
Project: Research
Stratification Of MRC Funded Scientific Technologies And Reagents For Rapid And Simple Dissemination To The Wider Scientific Community
Alessi, D. & Davies, P.
Medical Research Council
1/01/21 → 31/03/21
Project: Research
MRC PPU Covid Research
Alessi, D. & Davies, P.
Medical Research Council
18/10/20 → 17/07/21
Project: Research
World Class Labs
Alessi, D. & Davies, P.
Medical Research Council
1/10/20 → 31/03/21
Project: Research
Development of better approaches to study PINK1 structure (joint application with University Medical Centre Goettingen and University of Frankfurt)
Muqit, M.
1/08/20 → 31/07/22
Project: Research
Inhibiting SARS CoV2-PLpro Protease as a Strategy to Block Viral Replication
Kulathu, Y.
1/07/20 → 31/10/20
Project: Research
Rapid Research in Covid -19 Programme
Barrable, A., Belch, J., Boehnke, J., Booth, D., Brown, A., Cantrell, D., Chalmers, J., Coleman, S., Connell, D., Cuschieri, A., Dicker, A., Doney, A., Eftimie, R., Fang, M., Farre, A., Gamble, C., Howden, A., Krstajic, N., Lamond, A., Lee, M., Palmer, C., Parcell, B., Pearson, E., Shoemark, A. & Sixsmith, J.
1/06/20 → 30/09/21
Project: Research
Funding for new Mass Spec Platform
Alessi, D. & Davies, P.
1/04/20 → 31/03/21
Project: Research
Linking the GI tract with PD
Alessi, D., Mowat, C. & Sammler, E.
1/03/20 → 28/02/21
Project: Research
RNF12 E3 Ubiquitin Ligase Substrate Degraders as a Therapeutic Strategy in Tonne-Kalscheuer Syndrome (TOKAS)
Bustos, F. & Findlay, G.
1/03/20 → 28/02/22
Project: Research
DNA Interstrand Crosslink Repair and Chromatin Remodelling (ICL CHROM)
Rouse, J.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/02/20 → 26/04/22
Project: Research
Characterization of pT73 Rab10 Protein from XProChem and Supply of pRab8A and pRab10 Protein to Abcam for Assay Development
Alessi, D. & Davies, P.
1/01/20 → 14/08/21
Project: Research
Validation of antibodies to ubiquitin-conjugated proteins for mitophagy readouts
Muqit, M.
11/12/19 → 1/12/22
Project: Research
PPM1H Activators for Treatment of Parkinson's Disease
Alessi, D. & Gray, D.
1/09/19 → 30/03/21
Project: Research
Genome-wide and chemical screens to uncover novel upstream regulators of the LRRK2 signaling network
Alessi, D.
1/08/19 → 30/09/21
Project: Research
MRC Capital Prioritisation Bid 2019-20
Alessi, D. & Davies, P.
Medical Research Council
1/04/19 → 31/03/20
Project: Research
Antigen and Validation for New pS228 PINK1 and pT257 PINK1 Antibodies at Abcam
Muqit, M.
1/03/19 → 7/02/22
Project: Research
Processing of Branched DNA Molecules During Cytokinesis, Uncovering New Mechanisms of Genome Maintenance
Gartner, A., Lilley, D. & Rouse, J.
Biotechnology and Biological Sciences Research Council
1/12/18 → 30/06/22
Project: Research
LRRK2 and IBD
Alessi, D.
1/11/18 → 31/10/19
Project: Research
Correlating LRRK2 Activation Status to Phospho-Lipids in Parkinson's Disease
Alessi, D. & Sammler, E.
1/11/18 → 31/12/20
Project: Research
Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders
Muqit, M. & Sapkota, G.
10/09/18 → 9/09/21
Project: Research
Regulation of the Parkinson's kinase LRRK2
Alessi, D.
Parkinson's UK
3/09/18 → 2/09/21
Project: Research
Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)
Ciulli, A. & Sapkota, G.
1/09/18 → 2/09/22
Project: Research
Investigation of the LRRK2 G2385R Mutation (joint with Chinese National Human Genome Center Beijing (SinoGenoMax), Xuanwu Hospital of Capital Medical University)
Alessi, D. & Davies, P.
1/08/18 → 31/12/20
Project: Research
Validation and Antigen for the Abcam anti-Activated Parkin Antibody
Muqit, M.
1/07/18 → 12/04/21
Project: Research
MRC Capital Prioritisation
Alessi, D. & Davies, P.
Medical Research Council
1/04/18 → 31/03/19
Project: Research
Searching for New Protein Targets of the PINK1 and Parkin Genes in Parkinsons Disease
Muqit, M.
1/04/18 → 31/03/21
Project: Research
MRC Festival funding - Inside Out Science
Davies, P.
Medical Research Council
1/03/18 → 28/02/19
Project: Research
Method Development for Quantitative Assessment of Protein Turnover in Live Cells at Subcellular Resolution
Dinkova-Kostova, A., Muqit, M. & Saurin, A.
1/03/18 → 31/12/19
Project: Research
Video Production for Isolating PMBC and Neutrophils Protocol
Davies, P.
1/11/17 → 31/10/18
Project: Research
Validation of Abcam Rabbit anti-pS1292 LRRK Antibody
Alessi, D. & Davies, P.
27/09/17 → 26/09/18
Project: Research
Advancing Tissue Imaging Capabilities with Airyscan Confocal Microscopy (Multiuser Equipment Grant)
Ganley, I., Januschke, J., Muqit, M., Storey, K., Swedlow, J. & Tanaka, T.
Wellcome Trust
26/09/17 → 1/01/19
Project: Research
Investigating the Role of PINK 1 Dependent Phosphorylation
Muqit, M.
1/09/17 → 31/01/19
Project: Research
ADDRess - Joint Training and Research Network on Chromatin Dynamics and the DNA Damage Response (Joint with Foundation for Research and Technology, Greece, Erasmus University, Universities of Cologne and Copenhagen Centre for European Research into Biology & Medicine, Institute of Molecular Oncology Foundation, National Centre for Investigation in Oncology Carlos III, Cancer Research UK and Industrial Partners)
Rouse, J.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/08/17 → 31/07/18
Project: Research
Validation of Rabbit Monoclonal Antibodies against pS65
Muqit, M.
28/07/17 → 27/07/18
Project: Research
Activity Based Proteomics of E3 Ligases
Virdee, S.
Biotechnology and Biological Sciences Research Council
1/07/17 → 30/06/21
Project: Research
LRRK2 Inhibition to Systemic Bacterial Infection (Joint with Ottowa Hospital Research Institute)
Alessi, D.
1/07/17 → 30/06/19
Project: Research
Newton Fund PhD Placement Grant (Prosenjit Pal)
Muqit, M.
British Council
22/05/17 → 21/09/17
Project: Research
Molecular Mechanisms of DNA Replication Termination
Deegan, T.
Wellcome Trust
1/05/17 → 1/11/21
Project: Research
Role of Salt Inducible Kinases in Autoimmunity
Arthur, S. & Cohen, P.
1/04/17 → 30/09/20
Project: Research
MRC Capital Prioritisation Bid 2017/18
Alessi, D.
Medical Research Council
1/04/17 → 31/03/18
Project: Research
Defining the Role of Deubiquitylating Enzymes in Cancer Cell Survival
Kulathu, Y. & Leznicki, P.
1/03/17 → 31/12/17
Project: Research
Validation of RabMab Phospho-PINK1 (MJF-18 pT257, Clones 54-5 and 42-4) and Phospho-Parkin (MJF-17 pS65, Clones 26-4 and 1-4) Antibodies from Alternative Hybridomas at Abcam
Muqit, M.
23/11/16 → 22/11/17
Project: Research
Chemical Knockdown of LRRK2 by Small Molecule Protacs (Joint with Dana-Farber Cancer Institute)
Alessi, D. & Davies, P.
2/11/16 → 13/08/18
Project: Research
Towards a Unifying Theory of Parkinson's Disease - Investigation of the Biochemical and Genetic Role of Rab GTPases (joint with German Centre for Neurodegenerative Diseases)
Alessi, D. & Muqit, M.
Medical Research Council
17/10/16 → 16/10/18
Project: Research
Dissecting how the NLRP3 Inflammasome is Activated to Treat Chronic Inflammatory Diseases
Cohen, P. & Nanda, S.
15/10/16 → 14/10/17
Project: Research
Exploring the Role of a Newly Discovered Deubiquitinase in Proteostasis and Neurodegeneration
Kulathu, Y.
1/10/16 → 30/09/18
Project: Research
Collaborative Work with MJFF - Federico Diez Travel
Davies, P.
15/09/16 → 14/10/16
Project: Research