MRC PPU

Projects

Projects per year 2008 2026

• 17 Not started
• 32 Active
• 97 Finished

Projects per year

Search results

• Active

  Mouse Cell Line Characterisation (other inst: Rutgers University)

  Alessi, D.

  4/01/21 → 3/01/23

  Project: Research

• Determining the ligase and DUB landscape of mitochondrial and alpha-synuclein turnover

  Ganley, I., Sapkota, G. & Virdee, S.

  1/12/20 → 30/11/22

  Project: Research

• MRC PPU Covid Research

  Alessi, D. & Davies, P.

  Medical Research Council

  18/10/20 → 17/07/21

  Project: Research

• ASAP - Mapping the LRRK2 Signalling Pathway and its Interplay with other Parkinson's Disease Components

  Alessi, D. & Muqit, M.

  1/10/20 → 30/09/23

  Project: Research

• Defining Mechanisms of Protein Ufmylation

  Kulathu, Y.

  Biotechnology and Biological Sciences Research Council

  1/09/20 → 31/08/23

  Project: Research

• RNF12 E3 Ubiquitin Ligase Substrate Degraders as a Therapeutic Strategy in Tonne-Kalscheuer Syndrome (TOKAS)

  Bustos, F. & Findlay, G.

  1/03/20 → 28/02/22

  Project: Research

• DNA Interstrand Crosslink Repair and Chromatin Remodelling (ICL CHROM)

  Rouse, J.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/02/20 → 23/04/22

  Project: Research

• Characterization of pT73 Rab10 Protein from XProChem and Supply of pRab8A and pRab10 Protein to Abcam for Assay Development

  Alessi, D. & Davies, P.

  1/01/20 → 14/08/21

  Project: Research

• Validation of antibodies to ubiquitin-conjugated proteins for mitophagy readouts

  Muqit, M.

  11/12/19 → 1/12/22

  Project: Research

• Short Linear Interaction Motifs as Specificity Determinants in the Ubiquitin System - Discovery, Mechanisms and Therapuetic Opportunities (UBIMOTIF)

  Kulathu, Y.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/12/19 → 30/11/23

  Project: Research

• C5aR a Novel Immunomodulator of Metabolic Signalling and Energy Metabolism in Skeletal Muscle

  Ganley, I., Hundal, H., Lipina, C. & McCrimmon, R.

  Diabetes UK

  4/11/19 → 25/02/23

  Project: Research

• Genome-wide and chemical screens to uncover novel upstream regulators of the LRRK2 signaling network

  Alessi, D.

  1/08/19 → 14/01/23

  Project: Research

• Antigen and Validation for New pS228 PINK1 and pT257 PINK1 Antibodies at Abcam

  Muqit, M.

  1/03/19 → 7/02/22

  Project: Research

• Processing of Branched DNA Molecules During Cytokinesis, Uncovering New Mechanisms of Genome Maintenance

  Gartner, A., Lilley, D. & Rouse, J.

  Biotechnology and Biological Sciences Research Council

  1/12/18 → 30/11/21

  Project: Research

• Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders

  Muqit, M. & Sapkota, G.

  10/09/18 → 9/09/21

  Project: Research

• Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

  Ciulli, A. & Sapkota, G.

  3/09/18 → 2/09/22

  Project: Research

• Regulation of the Parkinson's kinase LRRK2

  Alessi, D.

  Parkinson's UK

  3/09/18 → 2/09/21

  Project: Research

• Functions and Applications of a Novel Pluripotency Signalling Pathway (Sir Henry Dale Fellowship)

  Findlay, G.

  Wellcome Trust

  1/09/18 → 31/08/23

  Project: Research

• Expanding the Druggable Proteome of Innate Immune Cells - Towards Synthetic Immune Regulation (Fellowship - with Scripps Research Institute)

  Cohen, P. & Kavanagh, M.

  Wellcome Trust

  1/07/18 → 30/06/22

  Project: Research

• Elucidation of Mechanisms that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases

  Arthur, S. & Cohen, P.

  Medical Research Council

  1/04/18 → 31/03/23

  Project: Research

• MRC QQR

  Alessi, D., Davies, P., Ganley, I., Kulathu, Y., Labib, K., Rouse, J., Rousseau, A., Sapkota, G., Virdee, S. & Walden, H.

  Medical Research Council

  1/04/18 → 31/03/23

  Project: Research

• The Molecular Mechanisms by which TRAF6 Regulates the Immune System

  Cohen, P.

  Wellcome Trust

  1/04/18 → 31/03/23

  Project: Research

• Novel Genome Integrity Pathways that Regulate DNA Replication Termination in Metazoa

  Labib, K.

  Cancer Research UK

  1/03/18 → 28/02/23

  Project: Research

• Regulation and Function of Protein FUBIylation (Lister Institute Research Prize 2017)

  Kulathu, Y.

  Lister Institute of Preventive Medicine

  1/10/17 → 30/09/22

  Project: Research

• Molecular Determinants of Intraepithelial Lymphocyte Function in Intestinal Infection (Sir Henry Dale Fellowship)

  Swamy, M.

  Wellcome Trust

  1/09/17 → 31/08/22

  Project: Research

• Activity Based Proteomics of E3 Ligases

  Virdee, S.

  Biotechnology and Biological Sciences Research Council

  1/07/17 → 30/06/21

  Project: Research

• Molecular Mechanisms of DNA Replication Termination

  Deegan, T.

  Wellcome Trust

  1/05/17 → 1/11/21

  Project: Research

• Regulation of DNA Interstrand Crosslink Repaid by Ubiquitin (ICLUB) (ERC Consolidator)

  Walden, H.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/09/16 → 31/08/21

  Project: Research

• Rab Detection Initiative (Joint with Stanford School of Medicine, Max Plank Institute, Neuroscience Research Australia and Parkinsons Institute California)

  Alessi, D. & Davies, P.

  1/08/16 → 31/07/21

  Project: Research

• Regulation of Lymphocyte Biology by Ubiquitin and Ubiquitin like Modifiers RELYUBL (Starting Grant)

  Kulathu, Y.

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/06/16 → 31/12/21

  Project: Research

• Young Investigator Programme

  Kulathu, Y.

  European Molecular Biology Organization

  1/01/16 → 31/12/26

  Project: Research

• Biochemical Analysis of the PINK-1 Parkin Signalling Pathway in Parkinson's Disease (Senior Clinical Fellowship)

  Muqit, M.

  Wellcome Trust

  1/07/13 → 31/12/23

  Project: Research