School of Life Sciences

  • United Kingdom

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Proteins Medicine & Life Sciences
Genes Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Hordeum Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Cells Chemical Compounds
Ubiquitin Medicine & Life Sciences
Genome Medicine & Life Sciences

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Profiles

No photo of Kris Aare

Aare, Kris

No photo of James Abbott

Abbott, James

No photo of Vackar Afzal

Afzal, Vackar

20112018

Research Output 1968 2019

(Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis

Macedo, D., Jardim, C., Figueira, I., Almeida, A. F., McDougall, G. J., Stewart, D., Yuste, J. E., Tomás-Barberán, F. A., Tenreiro, S., Outeiro, T. F. & Santos, C. N., 3 May 2018, In : Scientific Reports. 8, 1, p. 1-15 15 p., 6965

Research output: Contribution to journalArticle

Open Access
File
alpha-Synuclein
Phenol
Phenols
Parkinson Disease
Digestion

2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas’ disease

Thomas, M. G., De Rycker, M., Cotillo Torrejon, I., Thomas, J., Riley, J., Spinks, D., Read, K. D., Miles, T. J., Gilbert, I. H. & Wyatt, P. G., 1 Oct 2018, In : Bioorganic & Medicinal Chemistry Letters. 28, 18, p. 3025-3030 6 p.

Research output: Contribution to journalArticle

Chagas Disease
Parasites
Nifurtimox
Trypanosoma cruzi
Screening
2 Citations

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

Murugesan, D. , Ray, P. C. , Bayliss, T. , Prosser, G. A. , Harrison, J. R. , Green, K. , Soares De Melo, C. , Feng, T. S. , Street, L. J. , Chibale, K. , Warner, D. F. , Mizrahi, V. , Epemolu, O. , Scullion, P. , Ellis, L. , Riley, J. , Shishikura, Y. , Ferguson, L. , Osuna-Cabello, M. , Read, K. D. & 10 others Green, S. R., Lamprecht, D. A., Steyn, A. J. C., Ioerger, T. R., Sacchettini, J., Rhee, K. Y., Arora, K., Barry, C. E., Wyatt, P. G. & Boshoff, H. I. M., 8 Jun 2018, In : ACS Infectious Diseases. 4, 6, p. 954-969 16 p.

Research output: Contribution to journalArticle

Open Access
File
Quinazolinones
Structure-Activity Relationship
Mycobacterium tuberculosis
Adenosine Triphosphate
Allosteric Site

Prizes

Brian Cox Prize - Project of the Year

Rolf Black (Recipient) & Amy Cameron (Recipient), 2016

Prize: Prize (including medals and awards)

honors and awards

Delineating the ageing proteome: Convergence of ageing pathways in Caenorhabditis elegans

Vikram Narayan (Recipient), 1 Sep 2012

Prize: Fellowship awarded competitively

Caenorhabditis elegans
Proteome
Salaries and Fringe Benefits
Research

Long-term Doctoral Fellowship (1993-1994)

Karim Labib (Recipient), 1993

Prize: Fellowship awarded competitively

Activities 2013 2015

  • 11 Types of Public engagement and outreach - Schools engagement
  • 1 Festival/Exhibition

Gene Expression Advanced Higher Lecture

Zomerdijk, J. (Presenter)
19 Mar 2015

Activity: OtherTypes of Public engagement and outreach - Schools engagement

Bacteria Live in Communities - Craigie March 2015

Januschke, J. (Presenter)
13 Mar 2015

Activity: OtherTypes of Public engagement and outreach - Schools engagement

Incredible Immunology 2015 - Schools Day

Crocker, P. (Organiser)
8 May 2015

Activity: OtherTypes of Public engagement and outreach - Schools engagement

Press / Media

Tuberculosis drug may also target visceral leishmaniasis

Alan Fairlamb & Kevin Read

24/05/16

1 item of media coverage

Press/Media: Research

Student theses

A biophysical approach for the study of G-protein coupled receptor complexes

Author: Aristotelous, T., 2017

Supervisor: Hopkins, A. (Supervisor) & Hopkins Navratilova, I. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Adaptive optics stimulated emission depletion microscope for thick sample imaging

Author: Zdankowski, P., 2018

Supervisor: Swedlow, J. (Supervisor) & McGloin, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

African Trypanosome Genes Specifically Required for Fitness in vivo

Author: Shrimpton, J. W., 2017

Supervisor: Horn, D. (Supervisor)

Student thesis: Master's ThesisMaster of Science

File