School of Life Sciences

Projects

Projects per year 2002 2010 2011 2012 2013 2014 2015 2016 2017 2018 2023 2032

• 111 Active
• 206 Not started
• 771 Finished

Projects per year

Search results

• Finished

  Aref#d: 21932. The Interplay of Wnt and Notch Signalling in the Segmentation Clock Mechanism

  Dale, K. (Investigator)

  23/11/09 → 22/11/13

  Project: Research

  • Presomitic Mesoderm 100%
  • Notch 95%
  • Segmentation Clock 90%
  • Mesoderm 84%
  • Somitogenesis 67%

• Clinical PhD Fellowship: Shuaibu Dambatta

  Cantrell, D. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)

  15/11/09 → 14/11/12

  Project: Research

• Aref#d: 21456. mTOR as a Regulator of Airway and Vascular Development in the Fetal Lung

  Jovanovic, A. (Investigator) & Land, S. (Investigator)

  9/11/09 → 8/05/13

  Project: Research

• Aref#d: 21189. SUMMIT: Surrogate Markers for Micro- and Macro-vascular Hard Endpoints for Innovative Diabetes Tools (EC IMI)

  Belch, J. (Investigator), Colhoun, H. (Investigator), Ferguson, M. (Investigator), Houston, G. (Investigator), Khan, F. (Investigator), Leese, G. (Investigator), Morris, A. (Investigator), Palmer, C. (Investigator) & Pearson, E. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/09 → 31/10/14

  Project: Research

  • Type 2 Diabetes Mellitus (T2DM) 100%
  • Excess Pressure 100%
  • Cardiovascular Risk 75%
  • Pressure Parameters 66%
  • Reservoir Pressure 59%

• Aref#d: 22417. NUCLEOSOME 4D Nucleosome Structure and Function across Biological Scales and Biological Function (EC FP7 People, Marie Curie Initial Training Networks)

  Owen-Hughes, T. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/09 → 31/10/13

  Project: Research

• Aref#d: 21559. Molecular Mechanisms of Fungal Cell Wall Assembly (Programme Grant)

  van Aalten, D. (Investigator)

  Medical Research Council

  1/11/09 → 31/10/14

  Project: Research

  • O-linked N-acetylglucosamine (O-GlcNAc) 100%
  • Enzyme 81%
  • O-GlcNAcase 80%
  • Transferase 74%
  • N-Acetylglucosamine 56%

• Aref#d: 21151. Molecular Mechanisms of Assembly, Regulation and Substrate Recognition of the Heterotrimeric LKB1 Tumour Suppressor

  Alessi, D. (Investigator) & van Aalten, D. (Investigator)

  1/11/09 → 31/10/12

  Project: Research

• Aref#d: 21632. The Nedd8 Ubiquitin-like Protein Conjugation System and Regulation of Cullin-Ring E3 Ligases (European Research Council)

  Kurz, T. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/09 → 31/10/14

  Project: Research

• Aref#d: 21240. Myc-Induced mRNA Cap Methylation (PhD Studentship)

  Cowling, V. (Investigator)

  1/10/09 → 30/09/13

  Project: Research

• Aref#d: 21329. The Electron Microscope Data Bank EMDB (Joint with European Bioinformatics Institute)

  Swedlow, J. (Investigator)

  1/10/09 → 30/09/12

  Project: Research

• Aref#d: 21202. Jalview: A Sequence Analysis Resource

  Barton, G. (Investigator) & Martin, D. (Investigator)

  1/10/09 → 30/09/14

  Project: Research

  • Missense Variants 100%
  • Missense 91%
  • Spike 88%
  • SARS Coronavirus 88%
  • Angiotensin-converting Enzyme 2 (ACE2) 76%

• Aref#d: 21477. The Adenomatous Polyposis Protein in Colorectal Cancer; from Biochemistry to Tissue Architecture (Programme Grant)

  Nathke, I. (Investigator)

  1/10/09 → 30/09/15

  Project: Research

  • Adenomatous Polyposis Coli 100%
  • Interkinetic nuclear Migration 50%
  • Proteomics 50%
  • Catenin 50%
  • Intestinal Organoids 50%

• Aref#d: 21320. Antagonism of PI 3-Kinase Signalling by PTEN and SHIP2 (Programme Grant)

  Downes, P. (Investigator) & Leslie, N. (Investigator)

  Medical Research Council

  1/10/09 → 30/09/14

  Project: Research

  • Phosphatase 100%
  • Phosphoinositide 3-Kinase 79%
  • Phosphoinositide 3-kinase (PI3K) 72%
  • Lipid 68%
  • Phosphatase Activity 47%

• Aref#d: 21936. Mechanisms of Virulence Acquisition During Phytophthora-Host Associations (RSE/Scottish Government Marie Curie Personal Research Fellowship) - Dr Edgar Huitema

  Brown, J. (Investigator) & Huitema, E. (Investigator)

  Royal Society of Edinburgh

  1/10/09 → 30/09/14

  Project: Research

• Aref#d: 21931. Investigation into the Role of a New Protein Secretion System in the Virulence of the Opportunistic Pathogen, Serratia Marcescens (RSE/Scottish Government Personal Research Fellowship)

  Coulthurst, S. (Investigator) & Gadd , G. M. (Investigator)

  Royal Society of Edinburgh

  1/10/09 → 28/02/15

  Project: Research

• Clinical PhD Programme: Meghan Perry

  Cantrell, D. (Investigator), Fairlamb, A. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)

  7/09/09 → 6/10/14

  Project: Research

  • Visceral Leishmaniasis 100%
  • PA-824 50%
  • Arsenic in Drinking Water 50%
  • Oral Treatment 50%
  • R-enantiomer 50%

• Neurosteroids: Modulation of Spinal Cord GABAa Receptors by Naturally Occuring Analgesics (Clinical PhD Programme: Stephen Humble)

  Belelli, D. (Investigator), Cantrell, D. (Investigator), Hales, T. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)

  7/09/09 → 6/09/12

  Project: Research

• Aref#d: 22363. Molecular and Cellular Biology PhD Programme (4 Year PhD Studentship: Colin Hammond)

  Crocker, P. (Investigator) & Owen-Hughes, T. (Investigator)

  7/09/09 → 6/09/13

  Project: Research

• Clinical PhD Programme: Madhumita Dandapani

  Cantrell, D. (Investigator), Hardie, G. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)

  7/09/09 → 6/09/12

  Project: Research

• Clinical PhD Programme: Katherine Walker

  Cantrell, D. (Investigator), Hay, R. (Investigator), Lambert, J. (Investigator) & Marshall, S. (Investigator)

  7/09/09 → 6/09/12

  Project: Research

• Aref#d: 22450. Capital Award in Biomedical Science - The Centre for Molecular Medicine (CMM)

  Colhoun, H. (Investigator), Leigh, I. (Investigator), Marshall, S. (Investigator), McLean, I. (Investigator), Morris, A. (Investigator), Panteleyev, A. (Investigator), Proby, C. (Investigator), Schweiger, S. (Investigator), Smith, F. (Investigator), South, A. (Investigator) & Sutherland, C. (Investigator)

  1/09/09 → 31/08/14

  Project: Research

• Aref#d: 21290. A Multidisciplinary Approach to Microtubule-Kinetochore Attachment (Joint with European Inst of Oncology, Max-Planck Inst of Mole Cell Biology and University of Kyoto) (Programme Grant)

  Tanaka, T. (Investigator)

  1/09/09 → 31/08/13

  Project: Research

• Aref#d: 20985. Quantitative Analysis of Key Protein Phosphorylation Events Pathway Biomarkers of Metabolic Disease in Human Cells

  Ferguson, M. (Investigator) & Sutherland, C. (Investigator)

  Medical Research Council

  10/08/09 → 9/09/12

  Project: Research

  • CRMP2 100%
  • Mediator 70%
  • Semaphorin 70%
  • Glycogen Synthase Kinase 3 (GSK3) 66%
  • Associated Proteins 66%

• Aref#d: 21551. The Role of CB1 Receptors in Modulating Insulin Action and Energy Metabolism in Skeletal Muscle

  Hundal, H. (Investigator) & Irving, A. (Investigator)

  1/08/09 → 30/04/13

  Project: Research

• Aref#d: 21852. Understanding the Role of Class IIa-Histone Deacetylases in Normal B-Cell Development and Function (Career Establishment Award)

  Matthews, S. (Investigator)

  1/07/09 → 31/03/15

  Project: Research

• Aref#d: 20997. Factors Modulating the Effects of Filaggrin Haploinsufficiency in Ichthyosis Vulgaris and Atopic Eczema (Intermediate Research Fellowship - Dr Sara Brown)

  Brown, S. (Investigator), Brown, S. (Investigator), Leigh, I. (Investigator) & McLean, I. (Investigator)

  1/07/09 → 30/06/15

  Project: Research

  • Filaggrin Gene 100%
  • Filaggrin 100%
  • Eczema 100%
  • Atopic Eczema 75%
  • Dermatological Research 50%

• Aref#d: 21864. In Vivo Study of Domain Determinants for Electrical Synapse Assembly

  Hormuzdi, S. (Investigator)

  Anonymous Trust

  1/07/09 → 31/07/13

  Project: Research

• Aref#d: 20999. Electronic Sonotweezers: Particle Manipulation with Ultrasonic Arrays (joint with Universities of Bristol, Southampton and Glasgow)

  Cochran, S. (Investigator), MacDonald, M. (Investigator) & Weijer, K. (Investigator)

  1/06/09 → 30/11/13

  Project: Research

• Aref#d: 21318. Molecular Mechanisms of O-GlcNAc Signalling (Senior Fellowship Renewal)

  van Aalten, D. (Investigator)

  1/06/09 → 29/02/16

  Project: Research

  • O-linked N-acetylglucosamine (O-GlcNAc) 100%
  • Transferase 95%
  • O-GlcNAcase 93%
  • Enzyme 80%
  • O-GlcNAc Transferase 77%

• Aref#d: 21284. Construction of a Novel Digital Scanning Lightsheet Microscope and its Application in Measuring 3D Cell Behaviour and Movement in Embryos

  MacDonald, M. (Investigator) & Weijer, K. (Investigator)

  15/05/09 → 14/11/12

  Project: Research

• Aref#d: 20586. What are the Roles of Oomycete RXLR Effectors in the Establishment of Plant Disease? (joint with Warwick University). Was CO0221

  Birch, P. (Investigator)

  4/05/09 → 3/11/14

  Project: Research

  • Phytophthora infestans 100%
  • Infectious Agent 93%
  • Phytophthora Infestans 93%
  • P. Infestans 63%
  • RXLR Effector 59%

• Aref#d: 20552. Manipulating Lignin to Improve Biofuel Conversion of Plant Biomass (joint with University of York)

  Halpin, C. (Investigator)

  20/04/09 → 19/10/14

  Project: Research

  • Barley 100%
  • Lignin 94%
  • Saccharification 52%
  • Grains 47%
  • Digestibility 44%

• Aref#d: 20175. Molecular Mechanisms Control and Cellular Consequences of rRNA Gene Transcriptions by RNA Polymerase (Programme Grant)

  Zomerdijk, J. (Investigator)

  6/04/09 → 5/12/14

  Project: Research

  • RNA Polymerase I 100%
  • Transcription 66%
  • RNA Gene 46%
  • Polis 42%
  • Polymerase 40%

• Aref#d: 21652. Determination of Free Brain Fraction of WRAIR Next Generation Quinoline Methanols

  Read, K. (Investigator)

  1/04/09 → 31/03/14

  Project: Research

• Aref#d: 21887. DNDi Collaboration

  Fairlamb, A. (Investigator), Frearson, J. (Investigator), Gilbert, I. (Investigator), Read, K. (Investigator) & Wyatt, P. (Investigator)

  Drugs for Neglected Diseases Initiative (DNDi)

  1/04/09 → 31/12/12

  Project: Research

• Aref#d: 20710. Characterisation of the Ubiquitous Sulfate Transporter from the SulP Family (RSE/Scottish Government Personal Research Fellowship : Dr A Javelle)

  Javelle, A. (Investigator) & Palmer, T. (Investigator)

  Royal Society of Edinburgh

  1/02/09 → 31/01/14

  Project: Research

• Aref#d: 20039. Mechanisms Ensuring Sister Kinetochore Bi-Orientation on the Mitotic Spindle (Programme Grant)

  Tanaka, T. (Investigator)

  1/12/08 → 31/05/14

  Project: Research

  • Kinetochore 100%
  • Microtubule 80%
  • Microtubules 60%
  • Mitosis 60%
  • Biorientation 51%

• Aref#d: 20261. Meiosis in Barley; Manipulating Crossover Frequency and Distribution (LOLA Joint with University of Birmingham)

  Halpin, C. (Investigator)

  1/12/08 → 31/05/14

  Project: Research

  • Barley 100%
  • Meiotic Crossover 60%
  • Synapsis 60%
  • Recombination 54%
  • Meiosis 47%

• Aref#d: 20197. AEROPATH: The Identification, Characterisation and Exploitation of Novel Gram-negative Drug Targets (EC FP7 - Cooperation - Health)

  Brenk, R. (Investigator), Frearson, J. (Investigator), Hopkins, A. (Investigator) & Hunter, B. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/08 → 31/10/12

  Project: Research

• Aref#d: 20041. Determining the role of the SUMO-specific, ubiquitin ligase RNF4

  Hay, R. (Investigator), McGreavey, L. (Investigator) & O'Connor, P. (Investigator)

  13/10/08 → 12/10/12

  Project: Research

• Aref#d: 20731. The Biosynthesis of Glycoproteins in Trypanosoma Brucei: Basic and Translational Research

  Ferguson, M. (Investigator) & Gilbert, I. (Investigator)

  1/10/08 → 31/05/14

  Project: Research

  • Trypanosoma Brucei 100%
  • T. Brucei 43%
  • Glycoprotein 33%
  • Bloodstream Forms 28%
  • GPI-anchored Protein (GPI-AP) 24%

• Aref#d: 20224. Defining the Role of PTEN in the Regulation of Epithelial Cell Polarity

  Leslie, N.

  Association for International Cancer Research

  1/10/08 → 31/08/12

  Project: Research

• Aref#d: 21060. The Open Microscopy Environment: Towards the Development of a Scientific Data Management System

  Swedlow, J. (Investigator)

  1/10/08 → 31/03/13

  Project: Research

  • Experimental Biology 100%
  • Bioimage Informatics 100%
  • Biological Microscopy 66%
  • Data Management 66%
  • Cell Biology 66%

• Signalling Mechanisms Regulating Differentiation Progression in Mouse Embryonic Stem Cells and Embryos (Studentship - Emily Fang)

  Crocker, P. (Investigator) & Storey, K. (Investigator)

  8/09/08 → 7/09/12

  Project: Research

• Aref#d: 21205. Molecular & Cellular Biology PhD Programme (Emily Fang)

  Crocker, P. (Investigator)

  8/09/08 → 7/09/12

  Project: Research

• Aref#d: 21204. Molecular & Cellular Biology PhD Programme (Ella Rosenzweig)

  Crocker, P. (Investigator)

  8/09/08 → 7/09/12

  Project: Research

• The Role of Aryl Hydrocarbon Receptor in Cytotoxic T Cells (Studentship - Ella Rozenzweig)

  Cantrell, D. (Investigator) & Crocker, P. (Investigator)

  8/09/08 → 7/09/12

  Project: Research

• Aref#d: 21203. Molecular & Cellular Biology PhD Programme (Alistair Langlands)

  Crocker, P. (Investigator)

  8/09/08 → 7/09/12

  Project: Research

• Aref#d: 21206. Molecular & Cellular Biology PhD Programme (Helena Salmen)

  Crocker, P. (Investigator)

  8/09/08 → 7/09/12

  Project: Research

• Aref#d: 21207. Molecular & Cellular Biology PhD Programme (Nimmi Weerasinghe)

  Crocker, P. (Investigator)

  8/09/08 → 7/09/12

  Project: Research