School of Life Sciences

Projects

Projects per year 2002 2010 2011 2012 2013 2014 2015 2016 2017 2018 2023 2032

• 111 Active
• 206 Not started
• 771 Finished

Projects per year

Search results

• Finished

  Controlling mIcRobiomes CircuLations for bEtter food Systems (CIRCLES) (joint with Alma Mater Studiorum - Universita di Bologna as lead, PanepistimioThessalias, Bolton Alimentari and 26 others)

  Bulgarelli, D. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/18 → 31/10/24

  Project: Research

  • Microflora 100%
  • Microbiota 75%
  • Rhizosphere Microbiome 75%
  • Barley 68%
  • Rhizosphere 54%

• Male Contraceptive Drug Development Using a Novel Human Sperm Phenotypic Screening Platform (Grand Challenges Phase II)

  Andrews, P. (Investigator), Barratt, C. (Investigator), Gilbert, I. (Investigator), Martins Da Silva, S. (Investigator), Read, K. (Investigator) & Swedlow, J. (Investigator)

  Bill and Melinda Gates Foundation

  1/11/18 → 30/09/23

  Project: Research

  • Sperm Motility 100%
  • Male Contraceptive 70%
  • Medicinal Chemistry 58%
  • Small Molecules 58%
  • Sperm Function 58%

• Correlating LRRK2 Activation Status to Phospho-Lipids in Parkinson's Disease

  Alessi, D. (Investigator) & Sammler, E. (Investigator)

  1/11/18 → 31/12/20

  Project: Research

• LRRK2 and IBD

  Alessi, D. (Investigator)

  1/11/18 → 31/10/19

  Project: Research

• Connecting and Expanding RIKENs Systems Science of Biological Dynamics and OMEs Image Data Resource Databases (International Travel Award)

  Swedlow, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  5/10/18 → 4/11/18

  Project: Research

  • Image Data 100%
  • Open Images 100%
  • Biological Image 100%
  • Global View 100%
  • Microscopy Data 100%

• Polarity, membranes, and the Machinery that tethers

  Murray, D. (Investigator)

  5/10/18 → 4/10/19

  Project: Research

  • Phosphoinositide 100%
  • Phosphoinositides 55%
  • PIP5K1C 50%
  • PI(3,5)P2 50%
  • Phosphorylation Sites 50%

• Developing Small Molecule Cancer Therapeutics Targeting the RNA Splicing Machinery: Target Validation on STRAP/UNRIP

  Gray, D. (Investigator), Lamond, A. (Investigator), Petty, R. (Investigator) & Wyatt, P. (Investigator)

  1/10/18 → 31/12/20

  Project: Research

• A Reference Transcript Database for Improved Analysis of RNA-seq Data from Barley

  Brown, J. (Investigator) & Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/10/18 → 30/09/20

  Project: Research

  • Barley 100%
  • RNA Sequencing 90%
  • Transcriptome 61%
  • RNA Sequencing (RNA-seq) 57%
  • Reference Transcriptome 55%

• The Image Data Resource: Making Biological Imaging Data FAIR (Joint with EMBL-EBI) (Biomedical Resources Grant)

  Swedlow, J. (Investigator)

  1/10/18 → 1/04/22

  Project: Research

  • Bioimaging 100%
  • Data Type 69%
  • File Format 46%
  • Microscopy Data 46%
  • Open Microscopy Environment 38%

• Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders

  Muqit, M. (Investigator) & Sapkota, G. (Investigator)

  10/09/18 → 9/09/21

  Project: Research

• Regulation of the Parkinson's kinase LRRK2

  Alessi, D. (Investigator)

  Parkinson's UK

  3/09/18 → 2/09/21

  Project: Research

  • Leucine-rich Repeat Kinase 2 (LRRK2) 100%
  • Leucine-Rich Repeat 91%
  • Kinase 85%
  • Phosphotransferase 85%
  • Parkinson's Disease 41%

• DogTag - A Genetically Encoded Proximity Labelling Strategy to Capture Problematic Protein-Protein Interactions

  Hemsley, P. (Investigator)

  Biotechnology and Biological Sciences Research Council

  3/09/18 → 2/12/22

  Project: Research

• Functions and Applications of a Novel Pluripotency Signalling Pathway (Sir Henry Dale Fellowship)

  Findlay, G. (Investigator)

  1/09/18 → 31/08/23

  Project: Research

  • Rnf12 100%
  • Embryonic Stem Cell 80%
  • Ubiquitin-Conjugating Enzyme 69%
  • E3 Ubiquitin Ligase 59%
  • Intellectual Disability 53%

• Novel PROTAC-based Chemical Biology Approaches to Induced Protein Knockdown Across the Proteome (PhD Studentship - with Boehringer Ingelheim)

  Ciulli, A. (Investigator) & Sapkota, G. (Investigator)

  1/09/18 → 2/09/22

  Project: Research

  • Protein Catabolism 100%
  • Proteolysis Targeting chimera (PROTAC) 92%
  • Bromodomain-containing Protein 4 (BRD4) 57%
  • Bump-hole 46%
  • Melanoma 46%

• Application of Detailed Proteomics to Investigate Genetic mechanisms in Skin Differentiation and Barrier Function

  Brown, S. (Investigator) & Lamond, A. (Investigator)

  British Skin Foundation

  1/09/18 → 31/08/21

  Project: Research

• The Dundee Resource for Sequence Analysis and Structure Prediction. RELATED TO 36262A, B, C AND D

  Barton, G. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/09/18 → 31/08/24

  Project: Research

  • Missense 100%
  • Missense Variants 90%
  • Spike 90%
  • SARS Coronavirus 90%
  • Angiotensin-converting Enzyme 2 (ACE2) 78%

• Industrial Strategy MRC DTP Studentship for the University of Dundee

  Hunter, B. (Investigator) & MacKintosh, C. (Investigator)

  Medical Research Council

  1/09/18 → 28/02/22

  Project: Research

• 16 ERA-CAPS Barley Yield Associated Networks (Joint with IPK Gatersleben as lead and University of Minnesota)

  Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  13/08/18 → 30/06/22

  Project: Research

  • Barley 100%
  • RNA Sequencing 73%
  • Reference Transcriptome 54%
  • RNA Sequencing (RNA-seq) 48%
  • Transcriptome 48%

• Investigation of the LRRK2 G2385R Mutation (joint with Chinese National Human Genome Center Beijing (SinoGenoMax), Xuanwu Hospital of Capital Medical University)

  Alessi, D. (Investigator) & Davies, P. (Investigator)

  1/08/18 → 31/12/20

  Project: Research

• Defining and Deploying Rpi gene Diversity in S. Americanum to Control Late Blight in Potato (Joint with James Hutton Institute and The Sainsbury Lab, Norwich)

  Birch, P. (Investigator)

  Biotechnology and Biological Sciences Research Council

  4/07/18 → 30/09/21

  Project: Research

  • Infectious Agent 100%
  • Pathogen Effectors 64%
  • Phytophthora infestans 41%
  • P. Infestans 31%
  • Oomycetes 31%

• Exploration of Biosynthetic Carbohydrates as Vaccine Candidates for Streptococcus Pyogenes

  Dorfmueller, H. (Investigator)

  1/07/18 → 30/06/20

  Project: Research

  • Group A Streptococcus 100%
  • Streptococcus Group A 97%
  • Bacteriophage Endolysin 83%
  • Endolysin 83%
  • PlyC 83%

• Validation and Antigen for the Abcam anti-Activated Parkin Antibody

  Muqit, M. (Investigator)

  1/07/18 → 12/04/21

  Project: Research

• BioStudies and the Image Data Resource: Expanding Imaging Datasets, Linkage, Metadata and Value (Joint with EMBL-EBI) (Bioinformatics and Biological Resources Fund - BBR)

  Swedlow, J. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/07/18 → 30/06/21

  Project: Research

  • Bioimaging 100%
  • Data Type 75%
  • File Format 56%
  • Microscopy Data 37%
  • Biological Image 37%

• Expanding the Druggable Proteome of Innate Immune Cells - Towards Synthetic Immune Regulation (Fellowship - with Scripps Research Institute)

  Cohen, P. (Investigator) & Kavanagh, M. (Investigator)

  1/07/18 → 30/06/23

  Project: Research

• mRNA Cap: Directing Cell Function and Fate (Wolfson Research Merit Award)

  Cowling, V. (Investigator)

  1/07/18 → 30/06/23

  Project: Research

  • RNA 100%
  • Methyltransferase 79%
  • MRNA Cap 68%
  • Capping Phenomenon 66%
  • Gene Expression 57%

• Barley Mutant Workshop 2018

  Bulgarelli, D. (Investigator), Halpin, C. (Investigator), McKim, S. (Investigator) & Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  25/06/18 → 24/07/18

  Project: Research

• Regulation of Meiotic Chromosome Segregation by Post-Translational Modifications

  Pelisch, F. (Investigator)

  Medical Research Council

  14/05/18 → 13/11/23

  Project: Research

  • Caenorhabditis Elegans 100%
  • Meiosis 51%
  • Chromosome Segregation 41%
  • Kinetochore 37%
  • Meiosis I 33%

• UK National Phenotypic Screening Centre (NPSC)

  Hopkins, A. (Investigator)

  11/05/18 → 11/05/19

  Project: Research

• RSE IEP Bilateral Exchange Visit - Dr R Aswati Nair

  Simpson, G. (Investigator)

  Royal Society of Edinburgh

  1/05/18 → 31/05/18

  Project: Research

• mRNA Cap Regulation and Function in CD8 T Cells (TCAPS)

  Cowling, V. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/05/18 → 30/04/22

  Project: Research

  • RNA 100%
  • Capping Phenomenon 73%
  • Cap Formation 64%
  • MRNA Cap 64%
  • Messenger RNA 55%

• The Molecular Mechanisms by which TRAF6 Regulates the Immune System

  Cohen, P. (Investigator)

  1/04/18 → 31/03/24

  Project: Research

  • Ubiquitin 100%
  • HOIL-1L 88%
  • Ubiquitylation 79%
  • Ubiquitination 76%
  • Ligase 71%

• Searching for New Protein Targets of the PINK1 and Parkin Genes in Parkinsons Disease

  Muqit, M. (Investigator)

  1/04/18 → 31/03/21

  Project: Research

  • Copy number 100%
  • Mouse Cortical Neurons 100%
  • Single-cell Proteomics 100%
  • Data-dependent Acquisition 100%
  • Data-independent Acquisition 100%

• Cancer Ribosomics: Comprehensive Analysis of Ribosome and Translation Dynamics in Cancer

  Lamond, A. (Investigator) & Yoshikawa, H. (Investigator)

  1/04/18 → 31/03/20

  Project: Research

• MRC Capital Prioritisation

  Alessi, D. (Investigator) & Davies, P. (Investigator)

  Medical Research Council

  1/04/18 → 31/03/19

  Project: Research

• Elucidation of Mechanisms that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases

  Arthur, S. (Investigator) & Cohen, P. (Investigator)

  Medical Research Council

  1/04/18 → 31/03/23

  Project: Research

  • Ubiquitin 100%
  • Ligase 97%
  • HOIL-1L 92%
  • E3 Ligase 90%
  • Salt-inducible Kinase 63%

• MRC QQR

  Alessi, D. (Investigator), Davies, P. (Investigator), Ganley, I. (Investigator), Kulathu, Y. (Investigator), Labib, K. (Investigator), Liang, A. (Investigator), Rouse, J. (Investigator), Rousseau, A. (Investigator), Sapkota, G. (Investigator), Virdee, S. (Investigator) & Walden, H. (Investigator)

  Medical Research Council

  1/04/18 → 1/04/24

  Project: Research

  • Ubiquitination 100%
  • Protein Phosphorylation 100%
  • Video Project 80%
  • Audio 80%
  • Parkinson's Disease 80%

• Mechanisms Underlying Variation in Barley Hull Adhesion

  Campoli, C. (Investigator), Cook, S. (Investigator), McKim, S. (Investigator) & Waugh, R. (Investigator)

  Biotechnology and Biological Sciences Research Council

  1/04/18 → 31/08/22

  Project: Research

  • Barley 100%
  • Spadix 62%
  • Grains 58%
  • Cereals 50%
  • Anthesis 41%

• In4Derm: Topical by Design - HGSP application

  Woodland, A. (Investigator)

  19/03/18 → 18/04/20

  Project: Research

  • Drug Discovery 100%
  • Small-molecule Drug Discovery 20%
  • Project Screening 20%
  • Industrial Partner 20%
  • Screening Library 20%

• Method Development for Quantitative Assessment of Protein Turnover in Live Cells at Subcellular Resolution

  Dinkova-Kostova, A. (Investigator), Muqit, M. (Investigator) & Saurin, A. (Investigator)

  1/03/18 → 31/12/19

  Project: Research

  • Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) 100%
  • Transcription Factor Nrf2 100%
  • Microplate-based Assay 50%
  • Thermal Shift 50%
  • Protein Complex 50%

• IBH Rutherford Strategic Partners

  Halpin, C. (Investigator) & Waugh, R. (Investigator)

  1/03/18 → 28/02/19

  Project: Research

  • Sodium Content 100%
  • Na+ Transporter 100%
  • Natural Variants 100%
  • Barley 100%
  • Na + 100%

• Novel Genome Integrity Pathways that Regulate DNA Replication Termination in Metazoa

  Labib, K. (Investigator)

  1/03/18 → 1/09/23

  Project: Research

  • Helicase 100%
  • CMG Helicase 93%
  • Replisome 92%
  • DNA Synthesis 73%
  • Ubiquitylation 61%

• The Role of HMBS Phosphorylation in Acute Intermittent Porphyria

  Arthur, S. (Investigator), Ibbotson, S. (Investigator) & McGuire, V. (Investigator)

  1/03/18 → 29/02/20

  Project: Research

• MRC Confidence in Concept 2018

  Ferguson, M. (Investigator), Gray, D. (Investigator) & Wyatt, P. (Investigator)

  Medical Research Council

  1/03/18 → 29/02/20

  Project: Research

  • Neuroepithelial Cells 100%
  • RhoA 100%
  • Transforming Genes 100%
  • Anticancer Drugs 100%
  • Anticarcinogen 100%

• MRC Festival funding - Inside Out Science

  Davies, P. (Investigator)

  Medical Research Council

  1/03/18 → 28/02/19

  Project: Research

• A Newly Discovered Role for mRNA Methylation in Controlling Plant Gene Expression (PLANT-RNA-MET)

  Simpson, G. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/03/18 → 31/12/20

  Project: Research

  • RNA Sequence 100%
  • Arabidopsis 90%
  • RNA 75%
  • Direct RNA Nanopore Sequencing 60%
  • Arabidopsis Thaliana 60%

• Image Data Resources and Applications for the Human Cell Atlas

  Swedlow, J. (Investigator)

  1/03/18 → 28/02/19

  Project: Research

• MRC Proximity to Discovery 2017

  Brady, J. (Investigator), Brady, J. (Investigator), Ferguson, M. (Investigator) & Wyatt, P. (Investigator)

  Medical Research Council

  1/03/18 → 30/09/21

  Project: Research

• KRS Inhibitors: A Dundee Mini Portfolio

  Gilbert, I. (Investigator), Gray, D. (Investigator), Read, K. (Investigator) & Wyatt, P. (Investigator)

  1/01/18 → 1/07/23

  Project: Research

• Exploring Fundamental Mechanisms of Mutagenesis Conferred by the Chemotherapeutic DNA Cross Linking Agent Cisplantin Combining Next Generation Sequencing and Genetic Analysis Towards Selective Cancer Killing

  Gartner, A. (Investigator)

  World Cancer Research Fund International

  1/01/18 → 31/08/20

  Project: Research

  • Caenorhabditis Elegans 100%
  • DNA Repair Pathways 100%
  • DNA Repair 100%
  • Genome Integrity 62%
  • Germ Cells 60%

• The Molecular Cell Biology of Plant-oomycete Interactions: Understanding Disease and Disease Resistance (Wolfson Research Merit Award)

  Birch, P. (Investigator)

  1/01/18 → 31/12/22

  Project: Research