School of Life Sciences

Projects

Projects per year 2002 2010 2011 2012 2013 2014 2015 2016 2017 2018 2023 2033

• 111 Active
• 205 Not started
• 777 Finished

Projects per year

Search results

• Finished

  Accelerating Drug Discovery into Therapeutics and Commercial Benefit (Horizon Fund)

  Gray, D. (Investigator), Hopkins, A. (Investigator), Read, K. (Investigator), Woodland, A. (Investigator) & Wyatt, P. (Investigator)

  1/11/11 → 31/12/13

  Project: Research

• A Systems Approach to Chemotactic Cell Sorting During Development (Joint with University of Warwick)

  Dhir, R. (Investigator) & Weijer, K. (Investigator)

  1/11/11 → 31/05/15

  Project: Research

  • Primitive Streak 100%
  • Myosin II 100%
  • Cell Shape Change 100%
  • Cell Intercalation 100%
  • Streak Formation 100%

• Effects of LAT1 Amino Acid Transporter (SLC7AS) Gene Deletion on Mammalian Growth Nutrient Signalling and Foetal Development

  Taylor, P. (Investigator)

  3/10/11 → 2/10/14

  Project: Research

• Non-Genomic Mechanisms Stabilizing the Abundance of SNAT2, a Nutrient Transceptor Protein, in Response to Diverse Catabotic Signals

  Hundal, H. (Investigator) & Taylor, P. (Investigator)

  3/10/11 → 2/07/15

  Project: Research

  • Amino Acids 100%
  • Amino Acid Transporter 80%
  • Mammalian Target of Rapamycin (mTOR) 59%
  • SLC38A2 56%
  • SNAT2 56%

• The Relationship Between Micronutrient Status and Amino Acid Metabolism (RERAD) (Year 1)

  Hundal, H. (Investigator) & Taylor, P. (Investigator)

  Scottish Government

  3/10/11 → 31/03/16

  Project: Research

• The Molecular Mechanisms Underlying Secretory Component-Mediated Activation of Eosinophils (Foundation Grant)

  Woof, J. (Investigator)

  Asthma UK

  1/10/11 → 30/09/12

  Project: Research

• Genetic Screening in Pachyonychia Congenita

  Smith, F. (Investigator)

  1/10/11 → 30/09/13

  Project: Research

• The Open Microscopy Environment: Image Informatics for Biological Sciences (Joint with Imperial College, Oxford University, Institut Pasteur, Carnegie-Mellon University, University of Wisconsin, Harvard Medical School & University of Edinburgh)

  Swedlow, J. (Investigator)

  1/10/11 → 30/09/16

  Project: Research

  • Kinetochore 100%
  • Image Data 84%
  • Omeros 72%
  • Bacillus Subtilis Biofilm 64%
  • Microtubules 64%

• The Role of GM3, a Glycosphingolipid, as a Modulator of Skeletal Muscle Insulin Sensitivity

  Hundal, H. (Investigator)

  Diabetes UK

  1/10/11 → 31/01/15

  Project: Research

• Analysis of Rare-Keratinizing Disorders by Whole Exome Sequencing

  Smith, F. (Investigator)

  1/10/11 → 30/09/12

  Project: Research

• Role of fbx07 in Parkinson's Disease (Studentship)

  Alessi, D. (Investigator)

  1/10/11 → 30/09/15

  Project: Research

  • Kinase 100%
  • Phosphotransferase 100%
  • Leucine-rich Repeat Kinase 2 (LRRK2) 72%
  • Phosphorylation 69%
  • Parkin 54%

• Sugar Coat: Validation of UDP Galactopyranose Mutase as a Potential Antifungal Target (Clinical PhD Fellowship - Deborah Lockhart)

  Lockhart, D. (Investigator) & van Aalten, D. (Investigator)

  Medical Research Council

  5/09/11 → 4/09/14

  Project: Research

  • Aspergillus Fumigatus 100%
  • Aspergillus fumigatus 66%
  • Cell Wall 44%
  • UDP-galactopyranose mutase 33%
  • N-myristoyltransferase 33%

• Molecular and Cellular Biology PhD Programme (4 Year PhD - Mr Riccardo Trapannone)

  Crocker, P. (Investigator)

  1/09/11 → 31/08/15

  Project: Research

• Generation of LRRK1 Protein and Characterization of LRRK1 Mouse and Rabbit Monoclonal Antibodies

  Alessi, D. (Investigator)

  1/09/11 → 31/08/12

  Project: Research

• Molecular and Cellular Biology PhD Programme (4 Year PhD - Miss Nancy Ciang)

  Crocker, P. (Investigator)

  1/09/11 → 31/08/15

  Project: Research

• Molecular and Cellular Biology PhD Programme (4 Year PhD - Miss Laura Grasso)

  Crocker, P. (Investigator)

  1/09/11 → 31/08/15

  Project: Research

  • MRNA Cap 100%
  • RNA 100%
  • Methyltransferase 58%
  • CMTR1 50%
  • Cap Formation 50%

• Molecular and Cellular Biology PhD Programme (4 Year PhD - Miss Francesca Auciello)

  Crocker, P. (Investigator)

  1/09/11 → 31/08/15

  Project: Research

• Molecular and Cellular Biology PhD Programme (4 Year PhD - Mr Alistair Davies)

  Crocker, P. (Investigator)

  1/09/11 → 31/08/15

  Project: Research

• Biochemical Analysis of the PINK1 Kinase (Bursary - Hazel Rooney)

  Muqit, M. (Investigator)

  1/08/11 → 31/07/12

  Project: Research

• Preclinical Studies Towards Application of SiRNA Therapy in Epidermolysis Bullosa Simples (Joint with Solihull Hospital)

  McLean, I. (Investigator)

  1/08/11 → 31/10/14

  Project: Research

• Probing the Mechanism of Protein Export by the Bacterial Tat Transport System (Wolfson Research Merit Award)

  Palmer, T. (Investigator)

  1/08/11 → 31/07/16

  Project: Research

• Molecular and Cellular Biology PhD Programme (4 Year PhD - Miss Amy Grec)

  Crocker, P. (Investigator)

  1/08/11 → 31/08/14

  Project: Research

• Characterisation of the Bacterial Proteins YjeE, YeaZ and YgjD and Evaluation as a Potential Novel Antimicrobial Target (Clinical Pre-Doctoral Fellowship - James Cargill)

  Cargill, J. (Investigator) & Palmer, T. (Investigator)

  Medical Research Council

  1/08/11 → 31/07/14

  Project: Research

• Mechanisms of Inflammation and Hypoxia-Induced Responses Mediated by HIF and NF-KB in Cancer (Senior Research Fellowship)

  Lamond, A. (Investigator) & Rocha, S. (Investigator)

  1/08/11 → 1/08/17

  Project: Research

  • Von Hippel-Lindau 100%
  • Procollagen-Proline Dioxygenase 66%
  • Hypoxia-Inducible Factors 66%
  • Proteolysis 55%
  • Hypoxia Response 53%

• Development of Selective LRRK2 Inhibitors (Joint with Harvard University)

  Alessi, D. (Investigator)

  15/07/11 → 14/09/13

  Project: Research

• 3D Libraries Consortium

  Gilbert, I. (Investigator) & Wyatt, P. (Investigator)

  1/07/11 → 31/12/13

  Project: Research

• Investigation of an AMPK Phosphatase

  Blow, J. (Investigator) & Cohen, T. (Investigator)

  Diabetes UK

  1/07/11 → 31/08/18

  Project: Research

• How Does the Mac-1 Integrin Modulate Immune Processes?

  Fagerholm, S. (Investigator) & Watts, C. (Investigator)

  Anonymous Trust

  1/05/11 → 31/10/12

  Project: Research

• Signalling by Post-translational Modifications in Embryonic Stem Cells

  Stavridis, M. (Investigator)

  Anonymous Trust

  1/05/11 → 30/04/13

  Project: Research

• Unraveling the Role of AMPK as a Hypothalamic Glucose-Sensor

  Ashford, M. (Investigator), Hardie, G. (Investigator) & McCrimmon, R. (Investigator)

  Anonymous Trust

  1/05/11 → 31/12/12

  Project: Research

• Opening the Hepatitis C virus envelope to Structure-Based Drug Design

  Brighty, D. (Investigator), Dillon, J. (Investigator) & Tulloch, L. (Investigator)

  Anonymous Trust

  5/04/11 → 4/12/12

  Project: Research

• Host Translocation Requirements of the Cytoplasmic (CRN) Effector Protein Family in Phytophthora

  Huitema, E. (Investigator)

  4/04/11 → 3/07/14

  Project: Research

  • Tomato 100%
  • Phytophthora 100%
  • Chromatin 100%
  • Oomycetes 100%
  • DNA Binding 100%

• An Enduring Pipeline to Identify and Utilize Durable Late Blight Disease Resistance in Potato (Joint with SCRI & The Sainsbury Lab, Norwich)

  Birch, P. (Investigator)

  4/04/11 → 3/04/15

  Project: Research

  • Phytophthora Infestans 100%
  • Infectious Agent 92%
  • Potato 89%
  • Phytophthora infestans 85%
  • Resistance Genes 78%

• Role of CREB in Limiting Inflammation

  Arthur, S. (Investigator)

  Versus Arthritis

  1/04/11 → 31/03/14

  Project: Research

• Genome-Wide Analysis of Insulin Signalling by Ribosome Profiling

  Bjorklund, M. (Investigator)

  1/03/11 → 31/08/12

  Project: Research

• Investigation into the Role of a New Protein Secretion System in the Virulence of the Opportunistic Pathogen, Serratia Marcescens

  Coulthurst, S. (Investigator)

  28/02/11 → 27/05/13

  Project: Research

• Discovery and Development of Drug Candidates for Neglected Diseases (joint with industrial partner)

  Brenk, R. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Hopkins, A. (Investigator), Horn, D. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

  1/02/11 → 1/07/17

  Project: Research

  • Visceral Leishmaniasis 100%
  • Trypanosoma Brucei 80%
  • Trypanosoma Cruzi (T. cruzi) 76%
  • N-myristoyltransferase 65%
  • Diseases 64%

• Aref#d: 22422. The Cancer Research-UK Nucleic Acid Structure Research Group: Nucleic Acid Structure and Interactions with Proteins (Programme Grant)

  Lilley, D. (Investigator)

  1/01/11 → 31/12/15

  Project: Research

• Regulation of Adaptive Immunity by Proteolytic Systems

  Watts, C. (Investigator)

  1/01/11 → 31/12/17

  Project: Research

  • Cell Patterning 100%
  • PDK1 100%
  • Signaling Pathway 100%
  • Pathway Control 100%
  • Langerhans Cells 100%

• Mechanism and Regulation of RNA-directed Chromatin Modification (Career Development Award)

  Bayne, E. (Investigator) & Lamond, A. (Investigator)

  Medical Research Council

  1/01/11 → 31/12/15

  Project: Research

• K-Turn Structure in the Architecture of Functional RNA Molecules

  Lilley, D. (Investigator)

  1/01/11 → 31/12/14

  Project: Research

• Euro-BioImaging: Research Infrastructure for Imaging Technologies in Biological and Biomedical Sciences (joint with 38 other partners)

  Swedlow, J. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/12/10 → 30/11/13

  Project: Research

• Aref#d: 21989. RNA Processing and Neurodegeneration; Exploring Mechanisms and Modelling Disease (Joint with Kings College London, University of Manchester & MRC Lab of Molecular Biology)

  Rouse, J. (Investigator)

  Medical Research Council

  1/11/10 → 31/12/14

  Project: Research

  • Splicing Factor 100%
  • Alzheimer's Disease 100%
  • Neurodegenerative Diseases 100%
  • Hyperphosphorylation 100%
  • Chromatin Structure 100%

• Functional Analysis of the SLX4 Regulator of DNA Repair Nucleases (Dr Jamie Wilson)

  Cantrell, D. (Investigator), Lambert, J. (Investigator), Marshall, S. (Investigator), Rouse, J. (Investigator) & Wilson, J. (Investigator)

  1/11/10 → 31/10/13

  Project: Research

• Mechanism and Inhibition of Chitin Synthesis (Sir Henry Wellcome Fellowship)

  Dorfmueller, H. (Investigator) & van Aalten, D. (Investigator)

  1/11/10 → 31/01/15

  Project: Research

  • Biochemical Model 100%
  • NodC 100%
  • Processive 100%
  • Chitin Synthase 100%
  • Chitin Synthesis 100%

• The Role of O-GlcNAc in Bacterial Signal Transduction and Virulence (Return to Europe Fellowship)

  Rao, F. (Investigator) & van Aalten, D. (Investigator)

  1/11/10 → 31/10/12

  Project: Research

• The Role of the Proinflammatory ERK-NFkB Signalling Axis in the Pathogenesis of Fatty Acid Induced Insulin Resistance and its Counter Modulation by AMPK

  Hundal, H. (Investigator)

  Diabetes UK

  1/11/10 → 31/10/13

  Project: Research

• SUGABACT: The Role of O-GlcNAc in Bacterial Signal Transduction and Virulence (Fellow: Dr. Francesco Rao)

  Rao, F. (Investigator) & van Aalten, D. (Investigator)

  COMMISSION OF THE EUROPEAN COMMUNITIES

  1/11/10 → 31/10/14

  Project: Research

• Control of Noise in Eukaryotic Gene Expression (Senior Research Fellowship)

  Chubb, J. (Investigator) & Weijer, K. (Investigator)

  1/11/10 → 31/10/15

  Project: Research

  • Dynamics 100%
  • Dictyostelium 58%
  • Transcription 54%
  • Nuclear Organization 50%
  • RNA Dynamics 50%

• Translating Sonoptics - Exploiting Laser Applications in Generic Non-Invasive Delivery (Joint with University of St Andrews)

  Campbell, P. (Investigator) & McLean, I. (Investigator)

  1/10/10 → 30/09/14

  Project: Research