School of Life Sciences

  • United Kingdom

Research Output 1968 2020

2019

2D-DIGE as a tool in neuroproteomics

Weiland, F., 2019, Neuroproteomics. Li, K. W. (ed.). New York, p. 143-159 17 p. (Neuromethods; vol. 146).

Research output: Chapter in Book/Report/Conference proceedingChapter

Two-Dimensional Difference Gel Electrophoresis
Neurology
Proteome
Electrophoresis
Protein Isoforms
11 Downloads (Pure)

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites

Zhang, S., Sakuma, M., Deora, G. S., Levy, C. W., Klausing, A., Breda, C., Read, K. D., Edlin, C. D., Ross, B. P., Wright Muelas, M., Day, P. J., O'Hagan, S., Kell, D. B., Schwarcz, R., Leys, D., Heyes, D. J., Giorgini, F. & Scrutton, N. S., 24 Jul 2019, In : Communications Biology. 2, p. 1-10 10 p., 271.

Research output: Contribution to journalArticle

Open Access
File
Kynurenine 3-Monooxygenase
Kynurenine
Neurodegenerative Diseases
Huntington Disease
Prodrugs
10 Downloads (Pure)
Open Access
File
Heavy Metals
Catchments
Risk assessment
Heavy metals
Rivers
1 Citation (Scopus)
55 Downloads (Pure)

A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila

Hannaford, M., Loyer, N., Tonelli, F., Zoltner, M. & Januschke, J., 29 Jan 2019, In : Development. 146, 2, p. 1-11 11 p., dev170589.

Research output: Contribution to journalArticle

Open Access
File
Drosophila
Phosphotransferases
Drosophila Proteins
Cell Polarity
Nuclear Envelope
1 Citation (Scopus)
46 Downloads (Pure)

A comparative map of macroautophagy and mitophagy in the vertebrate eye

McWilliams, T. G., Prescott, A., Villarejo-Zori, B., Ball, G., Boya, P. & Ganley, I., 1 Jul 2019, In : Autophagy. 15, 7, p. 1296-1308 13 p.

Research output: Contribution to journalArticle

Open Access
File
Mitochondrial Degradation
Autophagy
Vertebrates
Retina
Homeostasis
19 Downloads (Pure)

A comparison of mainstream genotyping platforms for the evaluation and use of barley genetic resources

Darrier, B., Russell, J., Milner, S. G., Hedley, P. E., Shaw, P. D., Macaulay, M., Ramsay, L., Halpin, C., Mascher, M., Fleury, D. L., Langridge, P., Stein, N. & Waugh, R., 26 Apr 2019, In : Frontiers in Plant Science. 10, p. 1-14 14 p., 544.

Research output: Contribution to journalArticle

Open Access
File
genetic resources
genotyping
single nucleotide polymorphism
barley
gene frequency

A Continuous Flow Strategy for the Facile Synthesis and Elaboration of Semi-Saturated Heterobicyclic Fragments

Luise, N., Wyatt, E. W., Tarver, G. & Wyatt, P., 14 Feb 2019, In : European Journal of Organic Chemistry. 2019, 6, p. 1341-1349 9 p.

Research output: Contribution to journalArticle

fragments
synthesis
Hydrogenation
Quality control
Hydrogen
3 Citations (Scopus)
71 Downloads (Pure)

A critical comparison of technologies for a plant genome sequencing project

Paajanen, P., Kettleborough, G., Lopez-Girona, E., Giolai, M., Heavens, D., Baker, D., Lister, A., Wilde, G., Hein, I., Macaulay, I., Bryan, G. J. & Clark, M. D., 9 Jan 2019, In : Giga Science. 8, 3, p. 1-12 12 p., giy163.

Research output: Contribution to journalArticle

Open Access
File
Plant Genome
Genes
Genome
Technology
Benchmarking
17 Downloads (Pure)
Open Access
File
Stainless Steel
Polytetrafluoroethylene
Polytetrafluoroethylenes
titanium oxides
Titanium dioxide
1 Citation (Scopus)
113 Downloads (Pure)

Advances in targeted degradation of endogenous proteins

Roth, S., Fulcher, L. & Sapkota, G., 27 Apr 2019, In : Cellular and Molecular Life Sciences. 76, 14, p. 2761-2777 17 p.

Research output: Contribution to journalReview article

Open Access
File
Proteolysis
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Targeting
Protein Biosynthesis
2 Citations (Scopus)

A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for Use in Double Electron Electron Resonance Distance Measurements

Shah, A., Roux, A., Starck, M., Mosely, J. A., Stevens, M., Norman, D. G., Hunter, R. I., El Mkami, H., Smith, G. M., Parker, D. & Lovett, J. E., 4 Mar 2019, In : Inorganic Chemistry. 58, 5, p. 3015-3025 11 p.

Research output: Contribution to journalArticle

Electron resonance
Spin Labels
Distance measurement
Gadolinium
gadolinium
8 Downloads (Pure)

A highly mutagenised barley (cv. Golden Promise) TILLING population coupled with strategies for screening-by-sequencing

Schreiber, M., Barakate, A., Uzrek, N., Macaulay, M., Sourdille, A., Morris, J., Hedley, P. E., Ramsay, L. & Waugh, R., 24 Aug 2019, In : Plant Methods. 15, p. 1-14 14 p., 99.

Research output: Contribution to journalArticle

Open Access
File
Hordeum
barley
screening
mutation
Mutation
31 Downloads (Pure)

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Müller, B. & Connolly, B., Aug 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression
1 Citation (Scopus)
49 Downloads (Pure)

A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

Plummer, S., Wallace, S., Ball, G., Lloyd, R., Schiapparelli, P., Quiñones-Hinojosa, A., Hartung, T. & Pamies, D., 5 Feb 2019, In : Scientific Reports. 9, 1, p. 1-11 11 p., 1407.

Research output: Contribution to journalArticle

Open Access
File
temozolomide
Precision Medicine
Glioblastoma
Brain Neoplasms
Doxorubicin
5 Citations (Scopus)
55 Downloads (Pure)

Albugo candida race diversity, ploidy and host-associated microbes revealed using DNA sequence capture on diseased plants in the field

Jouet, A., Saunders, D. G. O., McMullan, M., Ward, B., Furzer, O., Jupe, F., Cevik, V., Hein, I., Thilliez, G. J. A., Holub, E., Oosterhout, C. V. & Jones, J. D. G., 1 Feb 2019, In : New Phytologist. 221, 3, p. 1529-1543 15 p.

Research output: Contribution to journalArticle

Open Access
File
Albugo candida
Plant Diseases
Ploidies
ploidy
Candida
16 Downloads (Pure)

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

Kline, R. A., Dissanayake, K. N., Hurtado, M. L., Martínez, N. W., Ahl, A., Mole, A. J., Lamont, D. J., Court, F. A., Ribchester, R. R., Wishart, T. M. & Murray, L. M., 6 Jun 2019, In : Neurobiology of Disease. 130, p. 1-16 16 p., 104496.

Research output: Contribution to journalArticle

Open Access
File
Wallerian Degeneration
Energy Metabolism
Axons
Oxidative Phosphorylation
Wounds and Injuries
9 Downloads (Pure)
Open Access
File
Carbonates
Nanoparticles
Fungi
Minerals
Amino Acids

Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In : Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Amino Acid Substitution
gamma-Aminobutyric Acid
Substitution reactions
Chemical activation

Analysis of DrkA kinase's role in STATa activation

Saga, Y., Iwade, Y., Araki, T., Ishikawa, M. & Kawata, T., 17 Jun 2019, In : Genes to Cells. 24, 6, p. 422-435 14 p.

Research output: Contribution to journalArticle

Phosphotransferases
Tyrosine
Dictyostelium
Phosphorylation
Protein-Tyrosine Kinases
65 Downloads (Pure)
Open Access
File
Methylenetetrahydrofolate Dehydrogenase (NADP)
dehydrogenases
inhibitors
Ligands
enzymes
22 Downloads (Pure)

A New Front in Microbial Warfare—Delivery of Antifungal Effectors by the Type VI Secretion System

Trunk, K., Coulthurst, S. & Quinn, J., 14 Jun 2019, In : Journal of Fungi. 5, 2, p. 1-13 13 p., 50.

Research output: Contribution to journalReview article

Open Access
File
Weapons
Fungi
Microbiota
Autophagy
Gram-Negative Bacteria
25 Downloads (Pure)

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R., Jun 2019, In : Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.

Research output: Contribution to journalArticle

Open Access
File
Drug Interactions
Clinical Trials
Pharmaceutical Preparations
Pharmacokinetics
Cytochrome P-450 CYP3A
7 Downloads (Pure)

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

Schmidt, N., Domingues, P., Golebiowski, F., Patzina, C., Tatham, M. H., Hay, R. T. & Hale, B. G., 27 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17399-17408 10 p.

Research output: Contribution to journalArticle

Open Access
File
Endogenous Retroviruses
Ubiquitin
Orthomyxoviridae
Antiviral Agents
Immunity
1 Citation (Scopus)
25 Downloads (Pure)

Antigen receptor control of methionine metabolism in T cells

Sinclair, L. V., Howden, A., Brenes Murillo, A., Spinelli, L., Hukelmann, J., Macintyre, A. N., Liu, X., Thomson, S., Taylor, P., Rathmell, J. C., Locasale, J. W., Lamond, A. & Cantrell, D. A., 27 Mar 2019, In : eLife. 8, 29 p., e44210.

Research output: Contribution to journalArticle

Open Access
File
Antigen Receptors
T-cells
Metabolism
Methionine
T-Lymphocytes
12 Downloads (Pure)

APETALA2 control of barley internode elongation

Patil, V., McDermott, H. I., Mcallister, T., Cummins, M., Clara Silva, J., Mollison, E., Meikle, R., Morris, J. A., Hedley, P. E., Waugh, R., Dockter, C., Hansson, M. & McKim, S., 12 Jun 2019, In : Development. 146, 11, p. 1-16 16 p., 170373.

Research output: Contribution to journalArticle

Open Access
File
Gibberellins
Hordeum
Inflorescence
Growth
MicroRNAs
5 Downloads (Pure)

A post-transcriptional respiratome regulon in trypanosomes

Trenaman, A., Glover, L., Hutchinson, S. & Horn, D., 26 Jul 2019, In : Nucleic Acids Research. 47, 13, p. 7063-7077 15 p.

Research output: Contribution to journalArticle

Open Access
File
Regulon
Trypanosomiasis
Membrane Glycoproteins
Trypanosoma brucei brucei
RNA-Binding Proteins
37 Downloads (Pure)

Application of a Sensitive and Reproducible Label-Free Proteomic Approach to Explore the Proteome of Individual Meiotic-Phase Barley Anthers

Lewandowska, D., Zhang, R., Colas, I., Uzrek, N. & Waugh, R., 2 Apr 2019, In : Frontiers in Plant Science. 10, p. 1-15 15 p., 393.

Research output: Contribution to journalArticle

Open Access
File
proteome
proteomics
anthers
meiosis
barley

A Practical Guide to Barley Crossing

Thomas, W. T. B., Bull, H., Booth, A., Hamilton, R., Forster, B. P. & Franckowiak, J. D., 1 Jan 2019, Barley: Methods and Protocols. Harwood, W. A. (ed.). New York: Humana Press, Vol. 1900. p. 21-36 16 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Hordeum
Inbreeding
Pollen
Seeds

Arsenic Toxicity: An Arsenic-Hyperaccumulating Fern Uses a Bacterial-like Tolerance Mechanism

Gadd, G. M., 17 Jun 2019, In : Current Biology. 29, 12, p. R580-R582 3 p.

Research output: Contribution to journalArticle

Ferns
Arsenic
arsenic
ferns and fern allies
Toxicity
1 Citation (Scopus)
35 Downloads (Pure)

Aurora B–INCENP localization at centromeres/inner kinetochores is required for chromosome bi-orientation in budding yeast

García-Rodríguez, L. J., Kasciukovic, T., Denninger, V. & Tanaka, T., 6 May 2019, In : Current Biology. 29, 9, p. 1536-1544.e4 13 p.

Research output: Contribution to journalArticle

Open Access
File
Kinetochores
kinetochores
Saccharomycetales
Centromere
centromeres
1 Citation (Scopus)

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., Van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M., Ahn, S-M. & 68 others, Boyault, S., Brock, J. E., Broeks, A., Butler, A., Desmedt, C., Dirix, L., Dronov, S., Fatima, A., Foekens, J. A., Gerstung, M., Hooijer, G. K. J., Jang, S. J., Jones, D. R., Kim, H-Y., King, T. A., Krishnamurthy, S., Lee, H. J., Lee, J-Y., Li, Y., McLaren, S., Menzies, A., Mustonen, V., O'Meara, S., Pauporté, I., Pivot, X., Purdie, C. A., Raine, K., Ramakrishnan, K., Rodríguez-González, F. G., Romieu, G., Sieuwerts, A. M., Simpson, P. T., Shepherd, R., Stebbings, L., Stefansson, O. A., Teague, J., Tommasi, S., Treilleux, I., Van den Eynden, G. G., Vermeulen, P., Vincent-Salomon, A., Yates, L., Caldas, C., Van't Veer, L., Tutt, A., Knappskog, S., Tan, B. K. T., Jonkers, J., Borg, Å., Ueno, N. T., Sotiriou, C., Viari, A., Futreal, P. A., Campbell, P. J., Span, P. N., Van Laere, S., Lakhani, S. R., Eyfjord, J. E., Thompson, A. M., Birney, E., Stunnenberg, H. G., van de Vijver, M. J., Martens, J. W. M., Børresen-Dale, A-L., Richardson, A. L., Kong, G., Thomas, G. & Stratton, M. R., 7 Feb 2019, In : Nature. 566, 7742, p. E1 1 p.

Research output: Contribution to journalArticle

Genome
Breast Neoplasms
Mutation
27 Downloads (Pure)

AVR2 targets BSL family members, which act as susceptibility factors to suppress host immunity

Turnbull, D., Wang, H., Breen, S., Malec, M., Naqvi, S., Yang, L., Welsh, L., Hemsley, P. A., Zhendong, T., Brunner, F., Gilroy, E. M. & Birch, P. R. J., 1 May 2019, In : Plant Physiology. 180, 1, p. 571-581 11 p.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Immunity
immunity
Solanum tuberosum
Brassinosteroids
52 Downloads (Pure)

A well supported multi gene phylogeny of 52 dictyostelia

Schilde, C., Lawal, H. M., Kin, K., Shibano-Hayakawa, I., Inouye, K. & Schaap, P., May 2019, In : Molecular Phylogenetics and Evolution. 134, p. 66-73 8 p.

Research output: Contribution to journalArticle

Open Access
File
Phylogeny
phylogeny
gene
Genes
genome
5 Citations (Scopus)
antibiotic resistance
Wetlands
Climate Change
Antibiotics
Microbial Drug Resistance

Bacterial community rather than metals shaping metal resistance genes in water, sediment and biofilm in lakes from arid northwestern China

Song, W., Qi, R., Zhao, L., Xue, N., Wang, L. & Yang, Y., 10 Aug 2019, In : Environmental Pollution. 254, p. 1-12 12 p., 113041.

Research output: Contribution to journalArticle

Biofilms
Lakes
China
Sediments
Genes
3 Citations (Scopus)

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 others, Greb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-Puxbaum, A., Ehrenhöfer-Wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M-Y., Owen-Hughes, T., Ettmayer, P., Pearson, M., McConnell, D. B. & Ciulli, A., Jul 2019, In : Nature Chemical Biology. 15, 7, p. 672-680 9 p.

Research output: Contribution to journalArticle

Proteolysis
Adenosine Triphosphatases
Biophysics
Neoplasms
Chromatin Assembly and Disassembly
35 Downloads (Pure)

Barley yield formation under abiotic stress depends on the interplay between flowering time genes and environmental cues

Wiegmann, M., Maurer, A., Pham, A., March, T. J., Al-Abdallat, A., Thomas, W. T. B., Bull, H. J., Shahid, M., Eglinton, J., Baum, M., Flavell, A. J., Tester, M. & Pillen, K., 25 Apr 2019, In : Scientific Reports. 9, p. 1-16 16 p., 6397.

Research output: Contribution to journalArticle

Open Access
File
Hordeum
Cues
Genes
Plant Development
Alleles

Bifunctional chemical probes inducing protein-protein interactions

Maniaci, C. & Ciulli, A., 13 Aug 2019, In : Current Opinion in Chemical Biology. 52, p. 145-156 12 p.

Research output: Contribution to journalReview article

Proteins
Ubiquitin-Protein Ligases
Molecules
Glues
Adhesives
62 Downloads (Pure)

Biotransformation of lanthanum by Aspergillus niger

Kang, X., Csetenyi, L. & Gadd, G., Jan 2019, In : Applied Microbiology and Biotechnology. 103, 2, p. 981-993 13 p.

Research output: Contribution to journalArticle

Open Access
File
Lanthanum
Aspergillus niger
Biotransformation
Biomass
Oxalates

Bisphenol A removal from a plastic industry wastewater by Dracaena sanderiana endophytic bacteria and Bacillus cereus NI

Suyamud, B., Thiravetyan, P., Gadd, G. M., Panyapinyopol, B. & Inthorn, D., 30 Aug 2019, In : International Journal of Phytoremediation. 9 p.

Research output: Contribution to journalArticle

Dracaena
Bacillus cereus
Waste Water
Plastics
Industry
8 Citations (Scopus)
57 Downloads (Pure)

Breeding progress and preparedness for mass-scale deployment of perennial lignocellulosic biomass crops switchgrass, miscanthus, willow and poplar

Clifton-Brown, J., Harfouche, A., Casler, M. D., Dylan Jones, H., Macalpine, W. J., Murphy-Bokern, D., Smart, L. B., Adler, A., Ashman, C., Awty-Carroll, D., Bastien, C., Bopper, S., Botnari, V., Brancourt-Hulmel, M., Chen, Z., Clark, L. V., Cosentino, S., Dalton, S., Davey, C., Dolstra, O. & 39 others, Donnison, I., Flavell, R., Greef, J., Hanley, S., Hastings, A., Hertzberg, M., Hsu, T. W., Huang, L. S., Iurato, A., Jensen, E., Jin, X., Jørgensen, U., Kiesel, A., Kim, D. S., Liu, J., McCalmont, J. P., McMahon, B. G., Mos, M., Robson, P., Sacks, E. J., Sandu, A., Scalici, G., Schwarz, K., Scordia, D., Shafiei, R., Shield, I., Slavov, G., Stanton, B. J., Swaminathan, K., Taylor, G., Torres, A. F., Trindade, L. M., Tschaplinski, T., Tuskan, G. A., Yamada, T., Yeon Yu, C., Zalesny, R. S., Zong, J. & Lewandowski, I., Jan 2019, In : Global Change Biology: Bioenergy. 11, 1, p. 118-151 34 p.

Research output: Contribution to journalArticle

Open Access
File
Miscanthus
Panicum virgatum
energy crops
Crops
Biomass
12 Downloads (Pure)

Bringing Open Data to Whole Slide Imaging

Besson, S., Leigh, R., Linkert, M., Allan, C., Burel, J-M., Carroll, M., Gault, D., Gozim, R., Li, S., Lindner, D., Moore, J., Moore, W., Walczysko, P., Wong, F. & Swedlow, J., 2019, Digital Pathology: 15th European Congress, ECDP 2019, Warwick, UK, April 10–13, 2019, Proceedings. Reyes-Aldasoro, C. C., Veta, M., Janowczyk, A., Bankhead, P. & Sirinukunwattana, K. (eds.). Switzerland: Springer , p. 3-10 8 p. (Lecture Notes in Computer Science; vol. 11435).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
Libraries
Reading
Pathology
10 Downloads (Pure)
Open Access
File
Burkholderia pseudomallei
Adenosine Monophosphate
Anti-Bacterial Agents
Ligands
Enzymes
27 Downloads (Pure)

CAPAM: the mRNA cap adenosine N6 methyltransferase

Cowling, V., 1 Mar 2019, In : Trends in Biochemical Sciences. 44, 3, p. 183-185 3 p., 1545.

Research output: Contribution to journalArticle

Open Access
File
mRNA guanylyltransferase
Methyltransferases
Adenosine
Messenger RNA
Methylation
17 Downloads (Pure)

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

Pravata, V., Muha, V., Gundogdu, M., Ferenbach, A., Kakade, P., Vandadi, V., Wilmes, A. C., Borodkin, V., Joss, S., Stavridis, M. & van Aalten, D., 23 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 30, p. 14961-14970 10 p.

Research output: Contribution to journalArticle

Open Access
File
Intellectual Disability
Host Factor 1 Protein
Missense Mutation
Proteome
Catalytic Domain
46 Downloads (Pure)

CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock

Carrieri, F., Murray, P., Ditsova, D., Ferris, M. A., Davies, P. & Dale, K., 1 Jul 2019, In : EMBO Reports. 20, 7, p. 1-22 22 p., e46436.

Research output: Contribution to journalArticle

Open Access
File
Somites
Periodicity
Clocks
Mesoderm
Ubiquitin-Protein Ligases
84 Downloads (Pure)

CDK7 is a component of the integrated stress response regulating SNAT2 (SLC38A2)/System A adaptation in response to cellular amino acid deprivation

Stretton, C., Lipina, C., Hyde, R., Cwiklinski, E., Hoffmann, T. M., Taylor, P. M. & Hundal, H. S., 1 Jun 2019, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1866, 6, p. 978-991 14 p.

Research output: Contribution to journalArticle

Open Access
File
Activating Transcription Factor 4
Amino Acids
Cyclin-Dependent Kinases
alvocidib
Phosphotransferases
Cell Cycle
Mesoderm
Computational Model
oscillation
cell cycle
1 Citation (Scopus)

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Girardini, M., Maniaci, C., Hughes, S., Testa, A. & Ciulli, A., 15 Jun 2019, In : Bioorganic & Medicinal Chemistry. 27, 12, p. 2466-2479 14 p.

Research output: Contribution to journalArticle

Open Access
Proteolysis
Ubiquitin-Protein Ligases
Degradation
Cullin Proteins
Ubiquitination

Challenges in developing collaborative interdisciplinary research between gastroenterologists and engineers

Cummins, G., Cox, B. F., Walker, J. D., Cochran, S. & Desmulliez, M. P. Y., 21 Jan 2019, In : Journal of Medical Engineering and Technology. 42, 6, p. 435-442 8 p.

Research output: Contribution to journalArticle

Gastroenterology
Engineers
Innovation
Health
Communication