School of Life Sciences

  • United Kingdom

Research Output 1968 2020

Review article
26 Citations (Scopus)

Synthetic glycosylphosphatidylinositol (GPI) anchors: how these complex molecules have been made

Nikolaev, A. V. & Al-Maharik, N., 2011, In : Natural Product Reports. 28, 5, p. 970-1020 51 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Synthetic Neoglycoconjugates of Cell-Surface Phosphoglycans of Leishmania as Potential Anti-parasite Carbohydrate Vaccines

Nikolaev, A. V. & Sizova, O. V., Jul 2011, In : Biochemistry-Moscow. 76, 7, p. 761-773 13 p.

Research output: Contribution to journalReview article

100 Citations (Scopus)

Target assessment for antiparasitic drug discovery

Frearson, J. A., Wyatt, P. G., Gilbert, I. H. & Fairlamb, A. H., Dec 2007, In : Trends in Parasitology. 23, 12, p. 589-595 7 p.

Research output: Contribution to journalReview article

56 Citations (Scopus)
60 Citations (Scopus)

T-cell antigen-receptor stoichiometry: Pre-clustering for sensitivity

Alarcón, B., Swamy, M., van Santen, H. M. & Schamel, W. W. A., 1 May 2006, In : EMBO Reports. 7, 5, p. 490-495 6 p.

Research output: Contribution to journalReview article

T-Cell Antigen Receptor
Stoichiometry
Cluster Analysis
T-cells
Ligands
103 Citations (Scopus)

Ten things to know about oomycete effectors

Schornack, S., Huitema, E., Cano, L. M., Bozkurt, T. O., Oliva, R., van Damme, M., Schwizer, S., Raffaele, S., Chaparro-Garcia, A., Farrer, R., Segretin, M. E., Bos, J. I. B., Haas, B. J., Zody, M. C., Nusbaum, C., Win, J., Thines, M. & Kamoun, S., Nov 2009, In : Molecular Plant Pathology. 10, 6, p. 795-803 9 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

The Algal Revolution

Brodie, J., Chan, C. X., De Clerck, O., Cock, J. M., Coelho, S. M., Gachon, C., Grossman, A. R., Mock, T., Raven, J. A., Smith, A. G., Yoon, H. S. & Bhattacharya, D., Aug 2017, In : Trends in Plant Science. 22, 8, p. 726-738 13 p.

Research output: Contribution to journalReview article

algae
biofuels
functional foods
eukaryotic cells
phenotype
1186 Citations (Scopus)

The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?

Hardie, D. G., Carling, D. & Carlson, M., Jul 1998, In : Annual Review of Biochemistry. 67, p. 821-855 35 p.

Research output: Contribution to journalReview article

260 Citations (Scopus)

The cancer chemopreventive actions of phytochemicals derived from glucosinolates

Hayes, J. D., Kelleher, M. O. & Eggleston, I. M., May 2008, In : European Journal of Nutrition. 47, p. 73-88 16 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)

The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin

Chen, S., Synowsky, S., Tinti, M. & MacKintosh, C., Nov 2011, In : Trends in Endocrinology and Metabolism. 22, 11, p. 429-436 8 p.

Research output: Contribution to journalReview article

245 Citations (Scopus)

The complex extracellular biology of streptomyces

Chater, K. F., Biro, S., Lee, K. J., Palmer, T. & Schrempf, H., Mar 2010, In : FEMS Microbiology Reviews. 34, 2, p. 171-198 28 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)
92 Downloads (Pure)

The ELF Honest Data Broker: Informatics enabling public-private collaboration in a precompetitive arena

Paillard, G., Cochrane, P., Jones, P. S., Van Hoorn, W. P., Caracoti, A., Van Vlijmen, H. & Pannifer, A. D., 1 Jan 2016, In : Drug Discovery Today. 21, 1, p. 97-102 6 p.

Research output: Contribution to journalReview article

Open Access
File
Informatics
Workflow
Triage
Intellectual Property
Drug Industry
103 Citations (Scopus)

The emergence of whole genome association scans in barley

Waugh, R., Jannink, J. L., Muehlbauer, G. J. & Ramsay, L., Apr 2009, In : Current Opinion in Plant Biology. 12, 2, p. 218-222 5 p.

Research output: Contribution to journalReview article

barley
genome
geneticists
linkage disequilibrium
plant breeding
3 Citations (Scopus)
127 Downloads (Pure)

The endocannabinoid system: no longer anonymous in the control of nitrergic signalling?

Lipina, C. & Hundal, H. S., 27 Jan 2017, In : Journal of Molecular Cell Biology. 9, 2, p. 91-103 13 p.

Research output: Contribution to journalReview article

Open Access
File
Endocannabinoids
Nitric Oxide
Reactive Nitrogen Species
Signal Transduction
Homeostasis
80 Citations (Scopus)

The endosome-lysosome pathway and information generation in the immune system

Watts, C., Jan 2012, In : Biochimica et Biophysica Acta. Proteins and Proteomics. 1824, 1, p. 14-21 8 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)
165 Downloads (Pure)

The Enigmatic Esx Proteins: Looking Beyond Mycobacteria

Unnikrishnan, M., Constantinidou, C., Palmer, T. & Pallen, M. J., Mar 2017, In : Trends in Microbiology. 25, 3, p. 192-204 13 p.

Research output: Contribution to journalReview article

Open Access
File
Mycobacterium
Bacteria
Proteins
Eukaryota
Membrane Proteins
33 Citations (Scopus)

The Evolution of Organellar Coat Complexes and Organization of the Eukaryotic Cell

Rout, M. P. & Field, M. C., Jun 2017, In : Annual Review of Biochemistry. 86, p. 637-657 21 p.

Research output: Contribution to journalReview article

Eukaryotic Cells
Organelles
Biochemistry
Proteins
Monomeric GTP-Binding Proteins
182 Citations (Scopus)

The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules

Watts, C., Jul 2004, In : Nature Immunology. 5, 7, p. 685-692 8 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)
102 Downloads (Pure)

The FAM83 family of proteins: from pseudo-PLDs to anchors for CK1 isoforms

Bozatzi, P. & Sapkota, G., 5 Jun 2018, In : Biochemical Society Transactions. 46, 3, p. 761-771 11 p.

Research output: Contribution to journalReview article

Open Access
File
Casein Kinase I
Anchors
Protein Isoforms
Phospholipase D
Protein Kinases
1 Citation (Scopus)

The Guanidine Riboswitch-A Poor Orphan No Longer

Lilley, D. M. J., 16 Feb 2017, In : Cell Chemical Biology. 24, 2, p. 130-131 2 p.

Research output: Contribution to journalReview article

Riboswitch
Guanidine
Gene expression
Ions
Ligands
47 Citations (Scopus)

The hows and whys of aerobic H-2 metabolism

Parkin, A. & Sargent, F., Apr 2012, In : Current Opinion in Chemical Biology. 16, 1-2, p. 26-34 9 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

The intermediate filament systems in the eye lens

Der Perng, M., Sandilands, A., Kuszak, J., Dahm, R., Wegener, A., Prescott, A. R. & Quinlan, R. A., 1 Dec 2004, In : Methods in Cell Biology. 2004, 78, p. 597-624 28 p.

Research output: Contribution to journalReview article

121 Citations (Scopus)

The International Barley Sequencing Consortium - At the threshold of efficient access to the barley genome

Schulte, D., Close, T. J., Graner, A., Langridge, P., Matsumoto, T., Muehlbauer, G., Sato, K., Schulman, A. H., Waugh, R., Wise, R. P. & Stein, N., 1 Jan 2009, In : Plant Physiology. 149, 1, p. 142-147 6 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
65 Downloads (Pure)

The Kink Turn, a Key Architectural Element in RNA Structure

Huang, L. & Lilley, D. M. J., 27 Feb 2016, In : Journal of Molecular Biology. 428, 5, p. 790-801 12 p.

Research output: Contribution to journalReview article

Open Access
File
Hydrogen
RNA
Adenine
Nucleotides
Metals
5 Citations (Scopus)

The kink-turn in the structural biology of RNA

Huang, L. & Lilley, D. M. J., 2018, In : Quarterly Reviews of Biophysics. 51, p. 1-32 32 p., e5.

Research output: Contribution to journalReview article

RNA
Metals
Ions
Base Pairing
Carrier Proteins
56 Citations (Scopus)
120 Downloads (Pure)

The mammalian ULK1 complex and autophagy initiation

Zachari, M. & Ganley, I. G., 12 Dec 2017, In : Essays in Biochemistry. 61, 6, p. 585-596 12 p.

Research output: Contribution to journalReview article

Open Access
File
Autophagy
Degradation
Poisons
Protein-Serine-Threonine Kinases
Quality control
223 Citations (Scopus)
126 Downloads (Pure)

The mechanisms of action of metformin

Rena, G., Hardie, D. G. & Pearson, E. R., Sep 2017, In : Diabetologia. 60, 9, p. 1577-1585 9 p.

Research output: Contribution to journalReview article

Open Access
File
Metformin
AMP-Activated Protein Kinases
Glycerolphosphate Dehydrogenase
Glucose
Health Services Needs and Demand
14 Citations (Scopus)

The mixotrophic nature of photosynthetic plants

Schmidt, S., Raven, J. A. & Paungfoo-Lonhienne, C., 2013, In : Functional Plant Biology. 40, 5, p. 425-438 14 p.

Research output: Contribution to journalReview article

526 Citations (Scopus)

The Nucleolus under Stress

Boulon, S., Westman, B. J., Hutten, S., Boisvert, F-M. & Lamond, A. I., 22 Oct 2010, In : Molecular Cell. 40, 2, p. 216-227 12 p.

Research output: Contribution to journalReview article

44 Citations (Scopus)

The physiology of growth arrest: Uniting molecular and environmental microbiology

Bergkessel, M., Basta, D. W. & Newman, D. K., Sep 2016, In : Nature Reviews Microbiology. 14, 9, p. 549-562 14 p.

Research output: Contribution to journalReview article

Environmental Microbiology
Bacterial Physiological Phenomena
Growth
Electrons
Bacteria
141 Citations (Scopus)

The plasmid-encoded killer system of Kluyveromyces lactis: A review

Stark, M. J. R., Boyd, A., Mileham, A. J. & Romanos, M. A., 1990, In : Yeast. 6, 1, p. 1-29 29 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

The possible evolution, and future, of CO2-concentrating mechanisms

Raven, J. A., Beardall, J. & Sánchez-Baracaldo, P., 1 Jun 2017, In : Journal of Experimental Botany. 68, 14, p. 3701-3716 16 p.

Research output: Contribution to journalReview article

Ribulose-Bisphosphate Carboxylase
concentrating
carbon dioxide
Carbon Cycle
Oxygenases
6 Citations (Scopus)
53 Downloads (Pure)

Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson's disease

Miller, S. & Muqit, M. M. K., 13 Jul 2019, In : Neuroscience Letters. 705, p. 7-13 7 p.

Research output: Contribution to journalReview article

Open Access
File
Mitochondrial Degradation
Parkinson Disease
Biomarkers
Ubiquitin-Specific Proteases
Therapeutics
90 Citations (Scopus)

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita

Leachman, S. A., Hickerson, R. P., Hull, P. R., Smith, F. J. D., Milstone, L. M., Lane, E. B., Bale, S. J., Roop, D. R., McLean, W. H. I. & Kaspar, R. L., Sep 2008, In : Journal of Dermatological Science. 51, 3, p. 151-157 7 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)
115 Downloads (Pure)

The regulation of lymphocyte activation and proliferation

Heinzel, S., Marchingo, J. M., Horton, M. B. & Hodgkin, P. D., Apr 2018, In : Current Opinion in Immunology. 51, p. 32-38 7 p.

Research output: Contribution to journalReview article

Open Access
File
Lymphocyte Activation
Antigens
Lymphocytes
T-Lymphocytes
Adaptive Immunity
44 Citations (Scopus)

The role of carbohydrate in sperm-ZP3 adhesion

Chapman, N. R. & Barratt, C. L., 1 Oct 1996, In : Molecular Human Reproduction. 2, 10, p. 767-774 8 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)
117 Downloads (Pure)

The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways

Cohen, P. & Strickson, S., May 2017, In : Cell Death & Differentiation. 24, p. 1153-1159 7 p.

Research output: Contribution to journalReview article

Open Access
File
Ubiquitin
Ubiquitin-Protein Ligases
TNF Receptor-Associated Factor 6
Phosphotransferases
Mitogen-Activated Protein Kinases
6 Citations (Scopus)
118 Downloads (Pure)

The second International Symposium on Fungal Stress: ISFUS

Alder-Rangel, A., Bailão, A. M., da Cunha, A. F., Soares, C. M. A., Wang, C., Bonatto, D., Dadachova, E., Hakalehto, E., Eleutherio, E. C. A., Fernandes, É. K. K., Gadd, G. M., Braus, G. H., Braga, G. U. L., Goldman, G. H., Malavazi, I., Hallsworth, J. E., Takemoto, J. Y., Fuller, K. K., Selbmann, L., Corrochano, L. M. & 8 others, von Zeska Kress, M. R., Bertolini, M. C., Schmoll, M., Pedrini, N., Loera, O., Finlay, R. D., Peralta, R. M. & Rangel, D. E. N., 1 Jun 2018, In : Fungal Biology. 122, 6, p. 386-399 14 p.

Research output: Contribution to journalReview article

Open Access
File
industrial microbiology
Industrial Microbiology
insect pathology
Exobiology
Photobiology
54 Citations (Scopus)

The segmentation clock mechanism moves up a notch

Gibb, S., Maroto, M. & Dale, J. K., Oct 2010, In : Trends in Cell Biology. 20, 10, p. 593-600 8 p.

Research output: Contribution to journalReview article

448 Citations (Scopus)

The Tat protein export pathway

Berks, B. C., Sargent, F. & Palmer, T., Jan 2000, In : Molecular Microbiology. 35, 2, p. 260-274 15 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

The tetrahydrobiopterin pathway and pain

Naylor, A. M., Pojasek, K. R., Hopkins, A. L. & Blagg, J., Jan 2010, In : Current Opinion in Investigational Drugs. 11, 1, p. 19-30 12 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)
39 Downloads (Pure)

The trypanosome alternative oxidase: a potential drug target?

Menzies, S. K., Tulloch, L. B., Florence, G. J. & Smith, T. K., Feb 2018, In : Parasitology. 145, 2, p. 175-183 9 p.

Research output: Contribution to journalReview article

Open Access
File
Trypanosomiasis
African trypanosomiasis
drugs
Trypanosoma brucei
therapeutics
10 Citations (Scopus)
141 Downloads (Pure)

The Type VI secretion system: a versatile bacterial weapon

Coulthurst, S., 1 May 2019, In : Microbiology. 165, 5, p. 503-515 13 p., 000789.

Research output: Contribution to journalReview article

Open Access
File
Weapons
Protein Array Analysis
Eukaryotic Cells
Gram-Negative Bacteria
Proteins
23 Citations (Scopus)

The use of tobacco mosaic virus and cowpea mosaic virus for the production of novel metal nanomaterials

Love, A. J., Makarov, V., Yaminsky, I., Kalinina, N. O. & Taliansky, M. E., 20 Jan 2014, In : Virology. 449, p. 133-139 7 p.

Research output: Contribution to journalReview article

Comovirus
Tobacco Mosaic Virus
Nanostructures
Capsid
Metals
281 Citations (Scopus)

The versatility and adaptation of bacteria from the genus Stenotrophomonas

Ryan, R. P., Monchy, S., Cardinale, M., Taghavi, S., Crossman, L., Avison, M. B., Berg, G., van der Lelie, D. & Dow, J. M., 1 Jan 2009, In : Nature Reviews Microbiology. 7, 7, p. 514-525 12 p.

Research output: Contribution to journalReview article

88 Citations (Scopus)

The zig-zag-zig in oomycete-plant interactions

Hein, I., Gilroy, E. M., Armstrong, M. R. & Birch, P. R. J., Jul 2009, In : Molecular Plant Pathology. 10, 4, p. 547-562 16 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Three wise centromere functions: see no error, hear no break, speak no delay

Tanaka, T. U., Clayton, L. & Natsume, T., Dec 2013, In : EMBO Reports. 14, 12, p. 1073-1083 11 p.

Research output: Contribution to journalReview article

Centromere
Kinetochores
Microtubules
Chromosomes
Chromosome Segregation
296 Citations (Scopus)

Through the "gatekeeper door": exploiting the active kinase conformation

Zuccotto, F., Ardini, E., Casale, E. & Angiolini, M., 8 Apr 2010, In : Journal of Medicinal Chemistry. 53, 7, p. 2681-2694 14 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)

Tipping the scales toward more effective antibodies

Woof, J. M., 2 Dec 2005, In : Science. 310, 5753, p. 1442-1443 2 p.

Research output: Contribution to journalReview article

103 Citations (Scopus)

TLR signalling regulated antigen presentation in dendritic cells

Watts, C., West, M. A. & Zaru, R., Feb 2010, In : Current Opinion in Immunology. 22, 1, p. 124-130 7 p.

Research output: Contribution to journalReview article