School of Life Sciences

  • United Kingdom

Research Output 1968 2020

687 Citations (Scopus)

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

Cuthbertson, D., Smith, K., Babraj, J., Leese, G., Waddell, T., Atherton, P., Wackerhage, H., Taylor, P. M. & Rennie, M. J., Dec 2004, In : FASEB Journal. 18, 15, p. 422- 424 3 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
56 Downloads (Pure)

An absorption origin for the soft excess in Seyfert 1 active galactic nuclei

Middleton, M., Done, C. & Gierliński, M., 17 Oct 2007, In : Monthly Notices of the Royal Astronomical Society. 381, 4, p. 1426-1436 11 p.

Research output: Contribution to journalArticle

Open Access
File
active galactic nuclei
accretion
accretion disks
galaxies
outflow
20 Citations (Scopus)

An acquired efflux system is responsible for copper resistance in Xanthomonas strain IG-8 isolated from China

Ryan, R. P., Ryan, D. J., Sun, Y-C., Li, F-M., Wang, Y. & Dowling, D. N., 1 Mar 2007, In : FEMS Microbiology Letters. 268, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

Xanthomonas
Copper
China
Multigene Family
Stenotrophomonas maltophilia
93 Citations (Scopus)

Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons

Trunk, K., Benkert, B., Quaeck, N., Muench, R., Scheer, M., Garbe, J., Jaensch, L., Trost, M., Wehland, J., Buer, J., Jahn, M., Schobert, M. & Jahn, D., Jun 2010, In : Environmental Microbiology. 12, 6, p. 1719-1733 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
113 Downloads (Pure)

An Affinity-directed PROtein Missile (AdPROM) system for targeted proteolysis

Fulcher, L., Macartney, T., Bozatzi, P., Hornberger, A., Rojas-Fernandez, A. & Sapkota, G., 26 Oct 2016, In : Open Biology. 6, 10, p. 1-9 9 p., 160255.

Research output: Contribution to journalArticle

Open Access
File
Proteolysis
Missiles
proteolysis
Proteins
proteins
56 Citations (Scopus)

An allelic series reveals essential roles for FY in plant development in addition to flowering-time control

Henderson, I. R., Liu, F., Drea, S., Simpson, G. G. & Dean, C., Jan 2005, In : Development. 132, 16, p. 3597-3607 11 p.

Research output: Contribution to journalArticle

Plant Development
RNA 3' End Processing
mRNA Cleavage and Polyadenylation Factors
Lethal Genes
Nuclear RNA
6 Citations (Scopus)

Analogues of D-glucosaminylphosphatidylinositol: synthesis of the glycosyl donors

Dix, A. P., Borissow, C. N., Ferguson, M. A. J. & Brimacombe, J. S., 1 Jan 2001, In : Tetrahedron Letters. 42, 1, p. 117-119 3 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Analogues of thiolactomycin as potential antimalarial agents

Jones, S. M., Urch, J. E., Kaiser, M., Brun, R., Harwood, J. L., Berry, C. & Gilbert, I. H., Jan 2005, In : Journal of Medicinal Chemistry. 48, 19, p. 5932-5941 10 p.

Research output: Contribution to journalArticle

Antimalarials
Growth
Parasites
Type II Fatty Acid Synthase
Enzymes
73 Citations (Scopus)

Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents

Jones, S. M., Urch, J. E., Brun, R., Harwood, J. L., Berry, C. & Gilbert, I. H., 15 Feb 2004, In : Bioorganic & Medicinal Chemistry. 12, 4, p. 683-692 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

An alternate route to phosphorylating DegU of Bacillus subtilis using acetyl phosphate

Cairns, L. S., Martyn, J. E., Bromley, K. & Stanley-Wall, N. R., 31 Mar 2015, In : BMC Microbiology. 15, 12 p., 78.

Research output: Contribution to journalArticle

Bacillus subtilis
Phosphorylation
Phosphoric Monoester Hydrolases
Phosphotransferases
Aspartic Acid
21 Citations (Scopus)

An alternative to radiation hybrid mapping for large-scale genome analysis in barley

Masoudi-Nejad, A., Nasuda, S., Bihoreau, M. T., Waugh, R. & Endo, T. R., 1 Dec 2005, In : Molecular Genetics and Genomics. 274, 6, p. 589-594 6 p.

Research output: Contribution to journalArticle

Radiation Hybrid Mapping
Hordeum
Chromosomes
Genome
Triticum
69 Citations (Scopus)
57 Downloads (Pure)

Analysing the atolls: X-ray spectral transitions of accreting neutron stars

Gladstone, J., Done, C. & Gierliński, M., 11 Jun 2007, In : Monthly Notices of the Royal Astronomical Society. 378, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

Open Access
File
atolls
neutron stars
accretion
x rays
hysteresis
52 Citations (Scopus)

Analysis of > 1000 single nucleotide polymorphisms in geographically matched samples of landrace and wild barley indicates secondary contact and chromosome-level differences in diversity around domestication genes

Russell, J., Dawson, I. K., Flavell, A. J., Steffenson, B., Weltzien, E., Booth, A., Ceccarelli, S., Grando, S. & Waugh, R., 2011, In : New Phytologist. 191, 2, p. 564-578 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Analysis of Conformational Changes in the DNA Junction-Resolving Enzyme T7 Endonuclease I on Binding a Four-Way Junction Using EPR

Freeman, A. D. J., Ward, R., El Mkami, H., Lilley, D. M. J. & Norman, D. G., 22 Nov 2011, In : Biochemistry. 50, 46, p. 9963-9972 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Analysis of cultivated potato (Solanum tuberosum) using intermicrosatellite amplification

Provan, J., Powell, W. & Waugh, R., 1 Jan 1996, In : Genome. 39, 4, p. 767-769 3 p.

Research output: Contribution to journalArticle

Solanum tuberosum
potatoes
cultivars
Piper
polyacrylamide

Analysis of DrkA kinase's role in STATa activation

Saga, Y., Iwade, Y., Araki, T., Ishikawa, M. & Kawata, T., 17 Jun 2019, In : Genes to Cells. 24, 6, p. 422-435 14 p.

Research output: Contribution to journalArticle

Phosphotransferases
Tyrosine
Dictyostelium
Phosphorylation
Protein-Tyrosine Kinases
2 Citations (Scopus)
111 Downloads (Pure)

Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia

Biddlestone, J., Druker, J., Shmakova, A., Ferguson, G., Swedlow, J. R. & Rocha, S., 13 May 2014, In : JoVE: Journal of Visualized Experiments. 87, 7 p., e51420.

Research output: Contribution to journalArticle

Open Access
File
RNA
Histone Demethylases
Cells
Oxygen
Prolyl Hydroxylases
18 Citations (Scopus)

Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3

Lipina, C., Huang, X., Finlay, D., McManus, E. J., Alessi, D. R. & Sutherland, C., 2005, In : Biochemical Journal. 392, 3, p. 633-639 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
72 Downloads (Pure)

Analysis of human protein replacement stable cell lines established using snoMEN-PR vector

Ono, M., Yamada, K., Endo, A., Avolio, F. & Lamond, A. I., 25 Apr 2013, In : PLoS ONE. 8, 4, 12 p., e62305.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)

Analysis of Human Small Nucleolar RNAs (snoRNA) and the Development of snoRNA Modulator of Gene Expression Vectors

Ono, M., Yamada, K., Avolio, F., Scott, M. S., van Koningsbruggen, S., Barton, G. J. & Lamond, A. I., 1 May 2010, In : Molecular Biology of the Cell. 21, 9, p. 1569-1584 16 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Analysis of hydrogenase 1 levels reveals an intimate link between carbon and hydrogen metabolism in Escherichia coli K-12

Pinske, C., McDowall, J. S., Sargent, F. & Sawers, R. G., 2012, In : Microbiology. 158, p. 856-868 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Analysis of intra-specific somatic hybrids of potato (Solanum tuberosum) using simple sequence repeats

Provan, J., Kumar, A., Shepherd, L., Powell, W. & Waugh, R., Dec 1996, In : Plant Cell Reports. 16, 3-4, p. 196-199 4 p.

Research output: Contribution to journalArticle

Solanum tuberosum
potatoes
microsatellite repeats
heterokaryon
automation
140 Citations (Scopus)

Analysis of microbial diversity in oligotrophic microbial fuel cells using 16S rDNA sequences

Phung, N. T., Lee, J., Kang, K. H., Chang, I. S., Gadd, G. M. & Kim, B. H., 1 Apr 2004, In : FEMS Microbiology Letters. 233, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

Bioelectric Energy Sources
Ribosomal DNA
Rivers
Clone Cells
Waste Water
2 Citations (Scopus)
41 Downloads (Pure)

Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel Syndrome

Llorens-Agost, M., Luessing, J., van Beneden, A., Eykelenboom, J., O'Reilly, D., Bicknell, L. S., Reynolds, J. J., van Koegelenberg, M., Hurles, M. E., Brady, A. F., Jackson, A. P., Stewart, G. S. & Lowndes, N. F., Dec 2018, In : Human Mutation. 39, 12, p. 1847-1853 7 p.

Research output: Contribution to journalArticle

Open Access
File
Ataxia Telangiectasia
Missense Mutation
Mutation
Microcephaly
Inborn Genetic Diseases
235 Citations (Scopus)
251 Downloads (Pure)

Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins

Lam, Y. W., Lamond, A. I., Mann, M. & Andersen, J. S., May 2007, In : Current Biology. 17, 9, p. 749-760 12 p.

Research output: Contribution to journalArticle

File
Ribosomal Proteins
ribosomal proteins
Nuclear Proteins
Degradation
degradation
126 Citations (Scopus)
124 Downloads (Pure)

Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes

Stockdale, C., Flaus, A., Ferreira, H. & Owen-Hughes, T., 2006, In : Journal of Biological Chemistry. 281, 24, p. 16279-88 10 p.

Research output: Contribution to journalArticle

Open Access
File
Chromatin Assembly and Disassembly
Nucleosomes
Yeast
Chromatin
Yeasts
28 Citations (Scopus)

Analysis of phenotypic evolution in Dictyostelia highlights developmental plasticity as a likely consequence of colonial multicellularity

Romeralo, M., Skiba, A., Gonzalez-Voyer, A., Schilde, C., Lawal, H., Kedziora, S., Cavender, J. C., Gloeckner, G., Urushihara, H. & Schaap, P., 7 Aug 2013, In : Proceedings of the Royal Society B. 280, 1764, 9 p., 20130976.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Analysis of potential duplicates in barley gene bank collections using re-sampling of microsatellite data

Lund, B., Ortiz, R., Skovgaard, I. M., Waugh, R. & Andersen, S. B., 1 Apr 2003, In : Theoretical and Applied Genetics. 106, 6, p. 1129-1138 10 p.

Research output: Contribution to journalArticle

gene banks
Hordeum
Microsatellite Repeats
genetic distance
Alleles
103 Citations (Scopus)

Analysis of quantitative traits in barley by the use of amplified fragment length polymorphisms

Powell, W., Thomas, W. T. B., Baird, E., Lawrence, P., Booth, A., Harrower, B., McNicol, J. W. & Waugh, R., 1 Jul 1997, In : Heredity. 79, 1, p. 48-59 12 p.

Research output: Contribution to journalArticle

Hordeum
Genome
Enzymes
Restriction Fragment Length Polymorphisms
Chromosomes, Human, Pair 5
45 Citations (Scopus)

Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA

Djupedal, I., Kos-Braun, I. C., Mosher, R. A., Soderholm, N., Simmer, F., Hardcastle, T. J., Fender, A., Heidrich, N., Kagansky, A., Bayne, E., Wagner, E. G. H., Baulcombe, D. C., Allshire, R. C. & Ekwall, K., 16 Dec 2009, In : EMBO Journal. 28, 24, p. 3832-3844 13 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Analysis of talpid3 and wild-type chicken embryos reveals roles for Hedgehog signalling in development of the limb bud vasculature

Davey, M. G., James, J., Paton, I. R., Burt, D. W. & Tickle, C., 1 Jan 2007, In : Developmental Biology. 301, 1, p. 155-65 11 p.

Research output: Contribution to journalArticle

Limb Buds
Hedgehogs
Chickens
Embryonic Structures
Hedgehog Proteins
15 Citations (Scopus)

Analysis of the barley bract suppression gene Trd1

Houston, K., Druka, A., Bonar, N., Macaulay, M., Lundqvist, U., Franckowiak, J., Morgante, M., Stein, N. & Waugh, R., Jun 2012, In : Theoretical and Applied Genetics. 125, 1, p. 33-45 13 p.

Research output: Contribution to journalArticle

94 Downloads (Pure)
Open Access
File
Deoxyribonuclease I
Peptides
DNA
Enzymes
Proteins
36 Citations (Scopus)

Analysis of the in Vivo Phosphorylation States of Proteins by Fast Atom Bombardment Mass Spectrometry and Other Techniques

Cohen, P., Gibson, B. W. & Holmes, C. F. B., 1991, In : Methods in Enzymology. 201, C, p. 153-168 16 p.

Research output: Contribution to journalArticle

Fast Atom Bombardment Mass Spectrometry
Phosphorylation
Mass spectrometry
Atoms
Phosphates
113 Citations (Scopus)

Analysis of the LKB1-STRAD-MO25 complex

Boudeau, J., Scott, J. W., Resta, N., Deak, M., Kieloch, A., Komander, D., Hardie, D. G., Prescott, A. R., van Aalten, D. M. F. & Alessi, D. R., 15 Dec 2004, In : Journal of Cell Science. 117, 26, p. 6365-6375 11 p.

Research output: Contribution to journalArticle

Neoplasms
Peutz-Jeghers Syndrome
Armadillos
AMP-Activated Protein Kinases
Protein-Serine-Threonine Kinases
12 Citations (Scopus)

Analysis of the regulatory role of Rpf/DSF cell-cell signaling system in the virulence of Xanthomonas campestris using proteomics

O'Connell, A., An, S-Q., McCarthy, Y., Schulte, F., Niehaus, K., He, Y-Q., Tang, J-L., Ryan, R. & Dow, J. M., 2013, In : Molecular Plant - Microbe Interactions.

Research output: Contribution to journalArticle

Xanthomonas campestris
Proteomics
proteomics
Virulence
virulence
61 Citations (Scopus)

Analysis of the response of Saccharomyces cerevisiae cells to Kluyveromyces lactis toxin

Butler, A. R., White, J. H. & Stark, M. J. R., 1 Jul 1991, In : Journal of General Microbiology. 137, 7, p. 1749-1757 9 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Kluyveromyces
G1 Phase
zymocin
Cell Cycle
26 Citations (Scopus)

Analysis of the SUMO2 proteome during HSV-1 Infection

Sloan, E., Tatham, M. H., Groslambert, M., Glass, M., Orr, A., Hay, R. T. & Everett, R. D., 22 Jul 2015, In : PLoS Pathogens. 11, 7, 34 p., e1005059.

Research output: Contribution to journalArticle

Open Access
Human Herpesvirus 1
Virus Diseases
Proteome
Sumoylation
Ubiquitin
33 Citations (Scopus)

Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor

Sutherland, T. E., Andersen, O. A., Betou, M., Eggleston, I. M., Maizels, R. M., van Aalten, D. & Allen, J. E., 27 May 2011, In : Chemistry & Biology. 18, 5, p. 569-579 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

An Ana2/Ctp/Mud complex regulates spindle orientation in Drosophila neuroblasts

Wang, C., Li, S., Januschke, J., Rossi, F., Izumi, Y., Garcia-Alvarez, G., Gwee, S. S. L., Soon, S. B., Sidhu, H. K., Yu, F., Matsuzaki, F., Gonzalez, C. & Wang, H., 13 Sep 2011, In : Developmental Cell. 21, 3, p. 520-33 14 p.

Research output: Contribution to journalArticle

Mushroom Bodies
Spindle Apparatus
Drosophila
Asymmetric Cell Division
Defects
28 Citations (Scopus)

An anatomy ontology to represent biological knowledge in Dictyostelium discoideum

Gaudet, P., Williams, J. G., Fey, P. & Chisholm, R. L., 18 Mar 2008, In : BMC Genomics. 9, p. - 12 p., 130.

Research output: Contribution to journalArticle

311 Citations (Scopus)

An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm

Armstrong, M. R., Whisson, S. C., Pritchard, L., Bos, J. I. B., Venter, E., Avrova, A. O., Rehmany, A. P., Bohme, U., Brooks, K., Cherevach, I., Hamlin, N., White, B., Fraser, A., Lord, A., Quail, M. A., Churcher, C., Hall, N., Berriman, M., Huang, S., Kamoun, S. & 3 others, Beynon, J. L., Birch, P. R. J. & Cook, R. J. (ed.), May 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 21, p. 7766-7771 6 p.

Research output: Contribution to journalArticle

Oomycetes
Solanum tuberosum
Phytophthora infestans
Cytoplasm
Alleles
18 Citations (Scopus)
126 Downloads (Pure)

An Aphid Effector Targets Trafficking Protein VPS52 in a Host-Specific Manner to Promote Virulence

Rodriguez, P. A., Escudero Martinez, C. & Bos, J., 3 Mar 2017, In : Plant Physiology. 173, 3, p. 1892-1903 12 p.

Research output: Contribution to journalArticle

Open Access
File
Aphids
protein transport
Protein Transport
Virulence
Aphidoidea
41 Citations (Scopus)

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes

Tye, C-K., Kasinathan, G., Barrett, M. P., Brun, R., Doyle, V. E., Fairlamb, A. H., Weaver, R. & Gilbert, I. H., 7 Apr 1998, In : Bioorganic & Medicinal Chemistry Letters. 8, 7, p. 811-816 6 p.

Research output: Contribution to journalArticle

92 Downloads (Pure)
Open Access
File
Methylenetetrahydrofolate Dehydrogenase (NADP)
dehydrogenases
inhibitors
Ligands
enzymes
26 Citations (Scopus)

A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes

Swamy, M., Minguet, S., Siegers, G. M., Alarcón, B. & Schamel, W. W. A., 31 Jul 2007, In : Journal of immunological methods. 324, 1-2, p. 74-83 10 p.

Research output: Contribution to journalArticle

Multiprotein Complexes
Antibodies
Epitopes
Protein Interaction Maps
Digitonin
91 Citations (Scopus)

A naturally occurring bacterial Tat signal peptide lacking one of the 'invariant' arginine residues of the consensus targeting motif

Hinsley, A. P., Stanley, N. R., Palmer, T. & Berks, B. C., 18 May 2001, In : FEBS Letters. 497, 1, p. 45-9 5 p.

Research output: Contribution to journalArticle

Protein Sorting Signals
tat Gene Products
Arginine
Plant Proteins
Salmonella
153 Citations (Scopus)

Anchoring and ordering NGS contig assemblies by population sequencing (POPSEQ)

Mascher, M., Muehlbauer, G. J., Rokhsar, D. S., Chapman, J., Schmutz, J., Barry, K., Munoz-Amatriain, M., Close, T. J., Wise, R. P., Schulman, A. H., Himmelbach, A., Mayer, K. F. X., Scholz, U., Poland, J. A., Stein, N. & Waugh, R., Nov 2013, In : Plant Journal. 76, 4, p. 718-727 10 p.

Research output: Contribution to journalArticle

Genome
genome
Hordeum
Population
barley