School of Life Sciences

  • United Kingdom

Research Output 1968 2020

2019

Identification and characterisation of Helicobacter pylori O-acetylserine-dependent cystathionine β-synthase, a distinct member of the PLP-II family

Devi, S., Tarique, K. F., Ali, M. F., Abdul Rehman, S. A. & Gourinath, S., 21 Aug 2019, In : Molecular Microbiology. 112, 2, p. 718-739 22 p.

Research output: Contribution to journalArticle

Cystathionine
Helicobacter pylori
Cysteine Synthase
Serine
Cysteine

Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1

Beck, E. M., Parnell, E., Cowley, A., Porter, A., Gillespie, J., Robinson, J., Robinson, L., Pannifer, A. D., Hamon, V., Jones, P., Morrison, A., McElroy, S., Timmerman, M., Rutjes, H., Mahajan, P., Wiejak, J., Luchowska-Stańska, U., Morgan, D., Barker, G., Rehmann, H. & 1 others, Yarwood, S. J., 12 Nov 2019, In : Cells. 8, 11

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Cyclic Nucleotides
Assays
Nucleotides
High-Throughput Screening Assays

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics

Popow, O., Paulo, J. A., Tatham, M., Volk, M., Rojas-Fernandez, A., Loyer, N., Newton, I., Januschke, J., Haigis, K. M. & Nathke, I., Sep 2019, In : Molecular Cancer Research. 17, 9, p. 1828-1841 14 p.

Research output: Contribution to journalArticle

Catenins
Adenomatous Polyposis Coli
Proteomics
Phosphotransferases
Colorectal Neoplasms
4 Citations (Scopus)

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others, Lowe, R. M., MacKenzie, C. J., MacLean, L., Manthri, S., Martin, F., Miguel-Siles, J., Nguyen, V. L., Norval, S., Osuna-Cabello, M., Woodland, A., Patterson, S., Pena, I., Quesada-Campos, M. T., Reid, I. H., Revill, C., Riley, J., Ruiz-Gomez, J. R., Shishikura, Y., Simeons, F. R. C., Smith, A., Smith, V. C., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Underwood, T., Gray, D. W., Fiandor, J. M., Gilbert, I. H., Wyatt, P. G., Read, K. D. & Miles, T. J., 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.

Research output: Contribution to journalArticle

Visceral Leishmaniasis
Leishmania major
Leishmania donovani
Standard of Care
Solubility
38 Downloads (Pure)

Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase

Torrie, L., Zuccotto, F., Robinson, D., Gray, D., Gilbert, I. & De Rycker, M., 31 May 2019, In : PLoS ONE. 14, 5, p. 1-16 16 p., e0217828.

Research output: Contribution to journalArticle

Open Access
File
Kinetochores
Trypanosoma brucei
kinetochores
Trypanosoma brucei brucei
phosphotransferases (kinases)
2 Citations (Scopus)
62 Downloads (Pure)

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening

Prakash, O., Führing, J., Post, J., Shepherd, S. M., Eadsforth, T. C., Gray, D., Fedorov, R. & Routier, F. H., 12 Mar 2019, In : Molecules and Cells. 24, 5, p. 1-16 16 p., 996.

Research output: Contribution to journalArticle

Open Access
File
Uridine Diphosphate Sugars
Small Molecule Libraries
Leishmania major
Biosensing Techniques
sugars
1 Citation (Scopus)
32 Downloads (Pure)

Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay

Zmuda, F., Sastry, L., Shepherd, S. M., Jones, D., Scott, A., Craggs, P. D., Cortes, A., Gray, D. W., Torrie, L. S. & De Rycker, M., Sep 2019, In : Antimicrobial Agents and Chemotherapy. 63, 9, p. 1-15 15 p., e00309-19.

Research output: Contribution to journalArticle

Open Access
File
High-Throughput Screening Assays
Proteasome Inhibitors
Trypanosoma cruzi
Proteasome Endopeptidase Complex
Luminescence
1 Citation (Scopus)
110 Downloads (Pure)

IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3

McCarthy, P. C., Phair, I. R., Greger, C., Pardali, K., McGuire, V. A., Clark, A. R., Gaestel, M. & Arthur, J. S. C., 17 Jan 2019, In : Immunology and Cell Biology. 97, 1, p. 54-71 18 p.

Research output: Contribution to journalArticle

Open Access
File
Neutrophil Infiltration
Mitogen-Activated Protein Kinase Kinases
p38 Mitogen-Activated Protein Kinases
Mast Cells
Cytokines

Immobilization of elemental mercury by biogenic Se nanoparticles in soils of varying salinity

Wang, X., Pan, X. & Gadd, G. M., 10 Jun 2019, In : Science of the Total Environment. 668, p. 303-309 7 p.

Research output: Contribution to journalArticle

Mercury
Selenium
immobilization
selenium
Nanoparticles

Improved models of the effects of winter chilling on blackcurrant (Ribes nigrum L.) show cultivar specific sensitivity to warm winters

Preedy, K., Brennan, R., Jones, H. & Gordon, S., 12 Oct 2019, In : Agricultural and Forest Meteorology. 280, p. 1-30 30 p., 107777.

Research output: Contribution to journalArticle

Ribes nigrum
black currants
cultivar
winter
cultivars
19 Downloads (Pure)

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

Vrahnas, C., Blank, M., Dite, T. A., Tatarczuch, L., Ansari, N., Crimeen-Irwin, B., Nguyen, H., Forwood, M. R., Hu, Y., Ikegame, M., Bambery, K. R., Petibois, C., Mackie, E. J., Tobin, M. J., Smyth, G. K., Oakhill, J. S., Martin, T. J. & Sims, N. A., 31 Jul 2019, In : Nature Communications. 10, 1, 16 p., 3436.

Research output: Contribution to journalArticle

Open Access
File
Osteocytes
Physiologic Calcification
Autophagy
bones
Bone

Inhibition of CorA dependent Magnesium Homeostasis is cidal in Mycobacterium tuberculosis

Park, Y., Ahn, Y-M., Jonnala, S., Oh, S., Fisher, J. M., Goodwin, M. B., Loerger, T. R., Via, L. E., Bayliss, T., Green, S. R., Ray, P. C., Wyatt, P. G., Barry, C. E. & Boshoff, H. I., 23 Sep 2019, In : Antimicrobial Agents and Chemotherapy. 63, 10, p. 1-14 14 p., e01006-19.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Magnesium
Homeostasis
Amides
Symporters
1 Citation (Scopus)
83 Downloads (Pure)

Insights into evolving global populations of Phytophthora infestans via new complementary mtDNA haplotype markers and nuclear SSRs

Martin, F. N., Zhang, Y., Cooke, D. E. L., Coffey, M. D., Grünwald, N. J. & Fry, W. E., 2 Jan 2019, In : PLoS ONE. 14, 1, p. 1-24 24 p., e0208606.

Research output: Contribution to journalArticle

Open Access
File
Phytophthora infestans
Mitochondrial DNA
Haplotypes
haplotypes
mitochondrial DNA
18 Downloads (Pure)

Integrative construction of regulatory region networks in 127 human reference epigenomes by matrix factorization

Liu, D., Davila-Velderrain, J., Zhang, Z. & Kellis, M., 22 Aug 2019, In : Nucleic Acids Research. 47, 14, p. 7235-7246 12 p.

Research output: Contribution to journalArticle

Open Access
File
Nucleic Acid Regulatory Sequences
Chromatin
Information Storage and Retrieval
Epigenomics
Genes
3 Citations (Scopus)

Investigating Mitophagy and Mitochondrial Morphology In Vivo Using mito-QC: A Comprehensive Guide

McWilliams, T. G. & Ganley, I. G., 2019, Autophagy: Methods and Protocols. Ktistakis, N. & Florey, O. (eds.). New York: Humana Press, Vol. 1880. p. 621-642 22 p. (Methods in Molecular Biology; vol. 1880).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Mitochondrial Degradation
Quality Control
Autophagy
Organelles
Homeostasis
Open Access
Nanocomposites
Urinary Catheters
Polytetrafluoroethylene
Silver
Catheters
15 Downloads (Pure)

In vitro reconstitution defines the minimal requirements for Cdc48-dependent disassembly of the CMG helicase in budding yeast

Mukherjee, P. & Labib, K., 10 Sep 2019, In : Cell Reports. 28, 11, p. 2777-2783.e4 11 p.

Research output: Contribution to journalArticle

Open Access
File
Cullin Proteins
Saccharomycetales
Multicarrier modulation
Ligases
Ubiquitin

Isolation, Purification, Generation, and Culture of Osteocytes

Gooi, J. H., Chia, L. Y., Vrahnas, C. & Sims, N. A., 2019, Humana Press. 13 p. (Methods in Molecular Biology (Clifton, N.J.))

Research output: Book/ReportBook

Osteocytes
Osteoblasts
Cell Line
Bone Matrix
Skeleton
20 Citations (Scopus)
210 Downloads (Pure)

Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of BRD9 and BRD7

Zoppi, V., Hughes, S. J., Maniaci, C., Testa, A., Gmaschitz, T., Wieshofer, C., Koegl, M., Riching, K. M., Daniels, D. L., Spallarossa, A. & Ciulli, A., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 699-726 28 p.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitination
Ligases
Proteolysis
Chromatin Assembly and Disassembly
Ubiquitin-Protein Ligases
1 Citation (Scopus)
29 Downloads (Pure)

Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

Zhou, R., Yang, O., Declais, A-C., Jin, H., Gwon, G. H., Freeman, A., Cho, Y., Lilley, D. & Ha, T., 1 Mar 2019, In : Nature Chemical Biology. 15, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cruciform DNA
Enzymes
Genetic Recombination
Bacteriophage T7
Chromosome Segregation
17 Downloads (Pure)

Juxta-membrane S-acylation of plant receptor-like kinases is likely fortuitous and does not necessarily impact upon function

Hurst, C., Wright, K. M., Turnbull, D., Leslie, K., Jones, S. & Hemsley, P., 2019, In : Scientific Reports. 9, p. 1-9 9 p., 12818.

Research output: Contribution to journalArticle

Open Access
File
acylation
phosphotransferases (kinases)
receptors
cysteine
mutation
23 Downloads (Pure)

Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator

Krutyhołowa, R., Hammermeister, A., Zabel, R., Abdel-Fattah, W., Reinhardt-Tews, A., Helm, M., Stark, M. J. R., Breunig, K. D., Schaffrath, R. & Glatt, S., 21 May 2019, In : Nucleic Acids Research. 47, 9, p. 4814-4830 17 p.

Research output: Contribution to journalArticle

Open Access
File
Transfer RNA
Adenosine Triphosphatases
Selenocysteine
Anticodon
Hydrolysis
9 Citations (Scopus)

Light Regulates Plant Alternative Splicing through the Control of Transcriptional Elongation

Godoy Herz, M. A., Kubaczka, M. G., Brzyżek, G., Servi, L., Krzyszton, M., Simpson, C., Brown, J., Swiezewski, S., Petrillo, E. & Kornblihtt, A. R., 7 Mar 2019, In : Molecular Cell. 73, 5, p. 1066-1074.e3 13 p.

Research output: Contribution to journalArticle

Alternative Splicing
Light
Chloroplasts
Arabidopsis
Carbon Cycle
2 Citations (Scopus)

Lignin engineering to improve saccharification and digestibility in grasses

Halpin, C., Apr 2019, In : Current Opinion in Biotechnology. 56, p. 223-229 7 p.

Research output: Contribution to journalReview article

Saccharification
Lignin
Poaceae
Biosynthesis
Livestock
71 Downloads (Pure)

Limited effects of the maternal rearing environment on the behaviour and fitness of an insect herbivore and its natural enemy

Slater, J. M., Gilbert, L., Johnson, D. & Karley, A. J., 11 Jan 2019, In : PLoS ONE. 14, 1, p. 1-19 19 p., e0209965.

Research output: Contribution to journalArticle

Open Access
File
Aphids
Herbivory
maternal effect
natural enemies
Insects
1 Citation (Scopus)
59 Downloads (Pure)

Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis

Eykelenboom, J., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T., 6 May 2019, In : Journal of Cell Biology. 218, 5, p. 1531-1552 22 p.

Research output: Contribution to journalArticle

Open Access
File
Mitosis
Chromatids
Chromosomes
Prophase
G2 Phase
12 Downloads (Pure)

Localization of Retinal Ca2+/Calmodulin-Dependent Kinase II-β (CaMKII-β) at Bipolar Cell Gap Junctions and Cross-Reactivity of a Monoclonal Anti-CaMKII-β Antibody With Connexin36

Tetenborg, S., Yadav, S. C., Brüggen, B., Zoidl, G. R., Hormuzdi, S. G., Monyer, H., van Woerden, G. M., Janssen-Bienhold, U. & Dedek, K., 28 Aug 2019, In : Frontiers in Molecular Neuroscience. 12, p. 1-13 13 p., 206.

Research output: Contribution to journalArticle

Open Access
File
Calcium-Calmodulin-Dependent Protein Kinases
Intercellular Junctions
Gap Junctions
Antibodies
Retina

Longitudinal analysis of the effect of water hardness on atopic eczema: evidence for gene-environment interaction

Jabbar-Lopez, Z. K., Craven, J., Logan, K., Greenblatt, D., Marrs, T., Radulovic, S., McLean, W. H. I., Lack, G., Strachan, D. P., Perkin, M. R., Peacock, J. L. & Flohr, C., 10 Oct 2019, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Hardness
Atopic Dermatitis
Water
Mutation

Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model

Baranger, K., Van Gijsel-Bonnello, M., Stephan, D., Carpentier, W., Rivera, S., Khrestchatisky, M., Gharib, B., De Reggi, M. & Benech, P., 2 Jul 2019, In : Neurotherapeutics. 18 p.

Research output: Contribution to journalArticle

Transgenic Mice
Alzheimer Disease
Genes
pantethine
Hypolipidemic Agents
8 Downloads (Pure)

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA

Izumikawa, K., Ishikawa, H., Yoshikawa, H., Fujiyama, S., Watanabe, A., Aburatani, H., Tachikawa, H., Hayano, T., Miura, Y., Isobe, T., Simpson, R. J., Li, L., Min, J. & Takahashi, N., 4 Nov 2019, In : Nucleic Acids Research. 47, 19, p. 10357-10372 16 p.

Research output: Contribution to journalArticle

Open Access
File
Acetyltransferases
Ribosomal RNA
Ribosomal DNA
Histones
Acetylation
2 Citations (Scopus)
115 Downloads (Pure)

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In : Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.

Research output: Contribution to journalArticle

Open Access
File
Lysine-tRNA Ligase
Cryptosporidiosis
Cryptosporidium parvum
Malaria
Plasmodium falciparum
19 Downloads (Pure)

l-α-Lysophosphatidylinositol (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK-dependent pathway

Robertson-Gray, O. J., Walsh, S. K., Ryberg, E., Jönsson-Rylander, A. C., Lipina, C. & Wainwright, C. L., Jun 2019, In : Pharmacology Research and Perspectives. 7, 3, p. 1-12 12 p., e00487.

Research output: Contribution to journalArticle

Open Access
File
Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Cannabidiol
p38 Mitogen-Activated Protein Kinases

Male genital lichen sclerosus and filaggrin

Shim, T. N., Brown, S. J., Francis, N. D., Dinneen, M., Hawkins, D., Muneer, A., Minhas, S., McLean, W. H. I. & Bunker, C. B., 17 Jun 2019, In : Clinical and Experimental Dermatology. 2 p.

Research output: Contribution to journalLetter

Lichen Sclerosus et Atrophicus
Genitalia
Autoimmunity
Skin Diseases
Epidermis
68 Downloads (Pure)

Mapping the H2 resistance effective against Globodera pallida pathotype Pa1 in tetraploid potato

Strachan, S. M. ., Armstrong, M. R., Kaur, A., Wright, K. M., Lim, T. Y., Jones, J., Bryan, G. J., Blok, V. & Hein, I., Apr 2019, In : Theoretical and Applied Genetics. 132, 4, p. 1283-1294 12 p.

Research output: Contribution to journalArticle

Open Access
File
Globodera pallida
Tetraploidy
pathotypes
Solanum tuberosum
tetraploidy
1 Citation (Scopus)
72 Downloads (Pure)
Open Access
File
NF-E2 Transcription Factor
NF-E2-Related Factor 2
Transcription Factors
Proteins
Assays
18 Downloads (Pure)
Open Access
File
Guanine
Methyltransferases
Molecular Dynamics Simulation
RNA
S-Adenosylmethionine
43 Downloads (Pure)

Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases

Fang, W., Sanz, A. B., Galan Bartual, S., Wang, B., Ferenbach, A., Farkaš, V., Hurtado-Guerrero, R., Arroyo, J. & van Aalten, D., 10 Apr 2019, In : Nature Communications. 10, 1, p. 1-10 10 p., 1669.

Research output: Contribution to journalArticle

Open Access
File
Aspergillus
Aspergillus fumigatus
redundancy
Cell Wall
Chitin
10 Downloads (Pure)

Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases

Gomez, R. C., Wawro, P., Lis, P., Alessi, D. & Pfeffer, S. R., 17 Oct 2019, In : Journal of Cell Biology. 14 p.

Research output: Contribution to journalArticle

Open Access
File
Guanine Nucleotide Dissociation Inhibitors
rab GTP-Binding Proteins
Guanosine Triphosphate
Phosphorylation
Membranes
27 Downloads (Pure)

Metabarcoding reveals a high diversity of woody host-associated Phytophthora spp. in soils at public gardens and amenity woodlands in Britain

Riddell, C. E., Frederickson-Matika, D., Armstrong, A. C., Elliot, M., Forster, J., Hedley, P. E., Morris, J., Thorpe, P., Cooke, D. E. L., Pritchard, L., Sharp, P. M. & Green, S., 16 May 2019, In : PeerJ. 7, p. 1-31 31 p., e6931.

Research output: Contribution to journalArticle

Open Access
File
public gardens
Phytophthora
United Kingdom
woodlands
Soil

Metabolic quirks and the colourful history of the Euglena gracilis secondary plastid

Novák Vanclová, A. M. G., Zoltner, M., Kelly, S., Soukal, P., Záhonová, K., Füssy, Z., Ebenezer, T. E., Lacová Dobáková, E., Eliáš, M., Lukeš, J., Field, M. C. & Hampl, V., 3 Oct 2019, In : New Phytologist.

Research output: Contribution to journalArticle

Euglena gracilis
Plastids
plastids
History
history
4 Citations (Scopus)
94 Downloads (Pure)

Metagenomic insights into the abundance and composition of resistance genes in aquatic environments: Influence of stratification and geography

Yang, Y., Li, Z., Song, W., Du, L., Ye, C., Zhao, B., Liu, W., Deng, D., Pan, Y., Lin, H. & Cao, X., Jun 2019, In : Environment International. 127, p. 371-380 10 p.

Research output: Contribution to journalArticle

Open Access
File
aquatic environment
stratification
gene
antibiotic resistance
metal
1 Citation (Scopus)

Metal bioavailability and the soil microbiome

Sullivan, T. S. & Gadd, G. M., 2019, Advances in Agronomy. Sparks, D. L. (ed.). Academic Press Inc., Vol. 155. p. 79-120 42 p. (Advances in Agronomy).

Research output: Chapter in Book/Report/Conference proceedingChapter

bioavailability
metals
metal
soil
microbial communities

Methods to analyze STUbL activity

Branigan, E., Plechanovová, A. & Hay, R. T., 3 Jan 2019, Methods in Enzymology. Elsevier, Vol. 618. p. 257-280 24 p. (Methods in Enzymology; vol. 618).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Ubiquitin-Protein Ligases
Ubiquitin
Genes
Assays
Substrates
2 Citations (Scopus)
21 Downloads (Pure)

Microbial rhodopsins are major contributors to the solar energy captured in the sea

Gómez-Consarnau, L., Raven, J. A., Levine, N. M., Cutter, L. S., Wang, D., Seegers, B., Arístegui, J., Fuhrman, J. A., Gasol, J. M. & Sañudo-Wilhelmy, S. A., 7 Aug 2019, In : Science Advances. 5, 8, p. 1-8 8 p., eaaw8855.

Research output: Contribution to journalArticle

Open Access
File
Microbial Rhodopsins
Solar Energy
Oceans and Seas
Phototrophic Processes
Rhodopsin
8 Citations (Scopus)

Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements

Deng, L., Wu, R. A., Sonneville, R., Kochenova, O. V., Labib, K., Pellman, D. & Walter, J. C., 7 Mar 2019, In : Molecular Cell. 73, 5, p. 915-929.e6 22 p.

Research output: Contribution to journalArticle

Gene Rearrangement
DNA Replication
Ubiquitination
Ovum
Xenopus
60 Downloads (Pure)

Molecular and bioinformatics analyses reveal two differentially expressed intracellular GH1 β-glucosidases from the rare alkalophilic fungus Stachybotrys microspora

Abdeljalil, S., Borgi, I., Carvalho, S., Jmal-Hammami, L. & Gargouri, A., 30 Jun 2019, In : Gene. 703, p. 134-144 11 p.

Research output: Contribution to journalArticle

Open Access
File
Stachybotrys
Microsporidia
Glucosidases
Computational Biology
Fungi
21 Downloads (Pure)

Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

Correia Faria, J., Glover, L., Hutchinson, S., Boehm, C., Field, M. C. & Horn, D., 9 Jul 2019, In : Nature Communications. 10, p. 1-14 14 p., 3023.

Research output: Contribution to journalArticle

Open Access
File
Trypanosoma Variant Surface Glycoproteins
Trypanosoma brucei brucei
Membrane Glycoproteins
exclusion
Epigenomics

Move to metabolism

Cantrell, D. A., 29 Mar 2019, In : Nature Reviews Immunology. 19, 1 p., 270.

Research output: Contribution to journalComment/debate

Calcium-Calmodulin-Dependent Protein Kinases
AMP-Activated Protein Kinases
T-Cell Antigen Receptor
Phosphotransferases
Adenosine Triphosphate
4 Citations (Scopus)
22 Downloads (Pure)

mRNA cap regulation in mammalian cell function and fate

Galloway, A. & Cowling, V., Mar 2019, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1862, 3, p. 270-279 10 p.

Research output: Contribution to journalReview article

Open Access
File
Cells
Messenger RNA
RNA Polymerase II
RNA
Cell Physiological Phenomena
1 Citation (Scopus)
Open Access
Y Chromosome
Chromosomes
Peptides
Ions
Proteomics