School of Life Sciences

  • United Kingdom

Research Output 1968 2020

2018
2 Citations (Scopus)

A tale of two eras: Phytoplankton composition influenced by oceanic paleochemistry

Giordano, M., Olivieri, C., Ratti, S., Norici, A., Raven, J. A. & Knoll, A. H., Sep 2018, In : Geobiology. 16, 5, p. 498-506 9 p.

Research output: Contribution to journalArticle

chemistry
phytoplankton
oceans
algae
biomass
3 Citations (Scopus)
136 Downloads (Pure)

ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A

Wan, X., Serrill, J. D., Humphreys, I. R., Tan, M., McPhail, K. L., Ganley, I. G. & Ishmael, J. E., 1 Mar 2018, In : Marine Drugs. 16, 3, p. 1-20 20 p., 77.

Research output: Contribution to journalArticle

Open Access
File
Depsipeptides
Autophagy
Thapsigargin
Biological Products
Fibroblasts
4 Citations (Scopus)
78 Downloads (Pure)

Atg7-Mediated Autophagy Is Involved in the Neural Crest Cell Generation in Chick Embryo

Wang, G., Chen, E., Liang, C., Liang, J., Gao, L., Chuai, M., Münsterberg, A., Bao, Y., Cao, L. & Yang, X., Apr 2018, In : Molecular Neurobiology. 55, 4, p. 3523-3536 14 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Autophagy
Chick Embryo
Neural Tube
Transfection
5 Citations (Scopus)
106 Downloads (Pure)

Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest

Allan, L. A., Skowyra, A., Rogers, K. I., Zeller, D. & Clarke, P. R., 3 Sep 2018, In : The EMBO Journal. 37, 17, p. 1-15 15 p., e96831.

Research output: Contribution to journalArticle

Open Access
File
Anaphase-Promoting Complex-Cyclosome
Mitosis
Degradation
Ubiquitin-Protein Ligases
Isoleucine
1 Citation (Scopus)
54 Downloads (Pure)

Author Correction: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis

Wall, R. J., Ferguson, D. J. P., Freville, A., Franke-Fayard, B., Brady, D., Zeeshan, M., Bottrill, A. R., Wheatley, S., Fry, A. M., Janse, C. J., Yamano, H., Holder, A. A., Guttery, D. S. & Tewari, R., 21 Aug 2018, In : Scientific Reports. 8, 1, p. 1-2 2 p., 12814.

Research output: Contribution to journalArticle

Open Access
File
Gametogenesis
Cytokinesis
Plasmodium
Mitosis
Chromosomes
8 Citations (Scopus)
125 Downloads (Pure)

Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice

Meakin, P. J., Jalicy, S. M., Montagut, G., Allsop, D. J. P., Cavellini, D. L., Irvine, S. W., McGinley, C., Liddell, M. K., McNeilly, A. D., Parmionova, K., Liu, Y-R., Bailey, C. S. L., Dale, J. K., Heisler, L. K., McCrimmon, R. J. & Ashford, M. L. J., 8 Jan 2018, In : Scientific Reports. 8, 1, p. 55 16 p., 55.

Research output: Contribution to journalArticle

Open Access
File
Obese Mice
Leptin
Amyloid
Obesity
Homeostasis
36 Citations (Scopus)
40 Downloads (Pure)

BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease

Prati, F., Bottegoni, G., Bolognesi, M. L. & Cavalli, A., 8 Feb 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 619-637 19 p.

Research output: Contribution to journalReview article

Open Access
File
Alzheimer Disease
Drug Discovery
Amyloid
Amyloid beta-Protein Precursor
Pharmaceutical Preparations
8 Citations (Scopus)
100 Downloads (Pure)

Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system

Wang, G., Liang, J., Gao, L-R., Si, Z-P., Zhang, X-T., Liang, G., Yan, Y., Li, K., Cheng, X., Bao, Y., Chuai, M., Chen, L-G., Lu, D-X. & Yang, X., 14 Feb 2018, In : Cell Death and Disease. 9, 2, p. 1-17 17 p., 234.

Research output: Contribution to journalArticle

Open Access
File
Cardiovascular System
Hyperglycemia
Autophagy
Chick Embryo
Embryonic Structures
84 Citations (Scopus)
121 Downloads (Pure)

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 439-449.e5 17 p.

Research output: Contribution to journalArticle

Open Access
File
Mitochondrial Degradation
Parkinson Disease
Dopaminergic Neurons
Microglia
Islets of Langerhans
7 Citations (Scopus)
75 Downloads (Pure)

Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei

Steketee, P. C., Vincent, I. M., Achcar, F., Giordani, F., Kim, D. H., Creek, D. J., Freund, Y., Jacobs, R., Rattigan, K., Horn, D., Field, M. C., MacLeod, A. & Barrett, M. P., 14 May 2018, In : PLoS Neglected Tropical Diseases. 12, 5, p. 1-24 24 p., e0006450.

Research output: Contribution to journalArticle

Open Access
File
S-Adenosylmethionine
Trypanosoma brucei brucei
African Trypanosomiasis
Metabolomics
Trypanosomiasis
3 Citations (Scopus)
89 Downloads (Pure)
Open Access
File
Microbial Genes
Ammonium Chloride
Lakes
Genes
Water
1 Citation (Scopus)

Biochemical and Structural Properties of Fungal Holliday Junction-Resolving Enzymes

Liu, Y., Freeman, A., Déclais, A-C., Gartner, A. & Lilley, D. M. J., 2018, Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination. Spies, M. & Malkova, A. (eds.). Academic Press, Vol. 600. p. 543-568 26 p. (Methods in Enzymology; vol. 600).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Cruciform DNA
Structural properties
Enzymes
Chaetomium
DNA
86 Downloads (Pure)
Open Access
File
Biofilms
Microbial Drug Resistance
Extracellular Matrix
Anti-Bacterial Agents
Bacteria

BLASTmap: A Shiny-Based Application to Visualize BLAST Results as Interactive Heat Maps and a Tool to Design Gene-Specific Baits for Bespoke Target Enrichment Sequencing

Baker, K., Stephen, G., Strachan, S., Armstrong, M. & Hein, I., 2018, Plant Pathogenic Fungi and Oomycetes. Ma, W. & Wolpert, T. (eds.). New York: Humana Press, Vol. 1848. p. 199-206 8 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hot Temperature
Genes
RNA Probes
Disease Resistance
DNA Probes

Blue carbon: past, present and future, with emphasis on macroalgae

Raven, J., Oct 2018, In : Biology Letters. 14, 10, p. 1-5 5 p., 20180336.

Research output: Contribution to journalReview article

Seaweed
macroalgae
Carbon
carbon
Temperature
3 Citations (Scopus)
105 Downloads (Pure)

Breaking Bad: How Viruses Subvert the Cell Cycle

Fan, Y., Sanyal, S. & Bruzzone, R., 19 Nov 2018, In : Frontiers in Cellular and Infection Microbiology. 8, p. 1-28 28 p., 396.

Research output: Contribution to journalReview article

Open Access
File
Cell Cycle
Viruses
Antigen Presentation
Protein Transport
Humoral Immunity
5 Citations (Scopus)
80 Downloads (Pure)

BRUSHY1/TONSOKU/MGOUN3 is required for heat stress memory

Brzezinka, K., Altmann, S. & Bäurle, I., 12 Jul 2018, In : Plant, Cell & Environment. p. 1-11 11 p.

Research output: Contribution to journalArticle

Open Access
File
heat stress
Hot Temperature
Chromatin
chromatin
Arabidopsis
1 Citation (Scopus)

Carbonate Disequilibrium in the External Boundary Layer of Freshwater Chrysophytes: Implications for Contaminant Uptake

Lavoie, M., Duval, J. F. L., Raven, J. A., Maps, F., Béjaoui, B., Kieber, D. J. & Vincent, W. F., 21 Aug 2018, In : Environmental Science & Technology. 52, 16, p. 9403-9411 9 p.

Research output: Contribution to journalArticle

Carbonates
disequilibrium
Boundary layers
Phytoplankton
boundary layer
82 Downloads (Pure)

Cell biological mechanisms regulating chick neurogenesis

Kasioulis, I. & Storey, K. G., 2018, In : International Journal of Developmental Biology. 62, 1/2/3, p. 167-175 9 p.

Research output: Contribution to journalArticle

Open Access
File
Neurogenesis
Centrosome
Neuroepithelial Cells
Biological Phenomena
Neurons
1 Citation (Scopus)

Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK

Fyffe, F. A., Hawley, S. A., Gray, A. & Hardie, D. G., 2018, AMPK : Methods and Protocols. Neumann, D. & Viollet, B. (eds.). New York: Humana Press, p. 69-86 18 p. (Methods in Molecular Biology; vol. 1732).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

AMP-Activated Protein Kinases
Adenosine Triphosphate
Adenosine Monophosphate
Ligands
Adenosine Diphosphate
1 Citation (Scopus)
74 Downloads (Pure)

Cell-type specific RNA-Seq reveals novel roles and regulatory programs for terminally differentiated Dictyostelium cells

Kin, K., Forbes, G., Cassidy, A. & Schaap, P., 22 Oct 2018, In : BMC Genomics. 19, 1, p. 1-18 18 p., 764.

Research output: Contribution to journalArticle

Open Access
File
Dictyostelium
RNA
Spores
Transcriptome
Genes
20 Citations (Scopus)
158 Downloads (Pure)

Challenges and recent progress in drug discovery for tropical diseases

De Rycker, M., Baragaña, B., Duce, S. L. & Gilbert, I. H., 25 Jul 2018, In : Nature. 559, 7715, p. 498-506 9 p.

Research output: Contribution to journalReview article

Open Access
File
Drug Discovery
Pharmaceutical Preparations
Communicable Diseases
Economics
Morbidity
76 Downloads (Pure)

Characterisation of a putative glutamate 5‐kinase from Leishmania donovani

Sienkiewicz, N., Ong, H. & Fairlamb, A., Jul 2018, In : FEBS Journal. 285, 14, p. 2662-2678 17 p.

Research output: Contribution to journalArticle

Open Access
File
Leishmania donovani
Aspartate Kinase
Proline
Glutamic Acid
Leishmania
1 Citation (Scopus)

Characterization of Protein Complexes Using Chemical Cross-Linking Coupled Electrospray Mass Spectrometry

Cummins, T. D. & Sapkota, G. P., 1 Jan 2018, Tissue Proteomics: Methods and Protocols. Sarwal, M. & Sigel, T. (eds.). New York: Humana Press, Vol. 1788. p. 43-61 19 p. (Methods in Molecular Biology; vol. 1788).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Mass Spectrometry
Green Fluorescent Proteins
Proteomics
Proteins
Tetracycline
5 Citations (Scopus)
90 Downloads (Pure)
Open Access
File
Metabolites
Drug Users
Metabolism
Opioid Analgesics
Urine
2 Citations (Scopus)
107 Downloads (Pure)

Chir99021 and Valproic acid reduce the proliferative advantage of Apc mutant cells

Langlands, A. J., Carroll, T. D., Chen, Y. & Nathke, I., 15 Feb 2018, In : Cell Death and Disease. 9, p. 1-10 10 p., 255.

Research output: Contribution to journalArticle

Open Access
File
Valproic Acid
Organoids
Growth
Cysts
Intestinal Polyposis
2 Citations (Scopus)

Chromatographic retention behaviour, modelling and optimization of a UHPLC-UV separation of the regioisomers of the Novel Psychoactive Substance (NPS) methoxphenidine (MXP)

Boateng, B. O., Fever, M., Edwards, D., Petersson, P., Euerby, M. R. & Sutcliffe, O. B., 10 May 2018, In : Journal of Pharmaceutical and Biomedical Analysis. 153, p. 238-247 10 p.

Research output: Contribution to journalArticle

Isomers
Static Electricity
Ionization
Electrostatics
1-(1-(2-methoxyphenyl)-2-phenylethyl)piperidine
5 Citations (Scopus)
105 Downloads (Pure)

Chronic pain in Pachyonychia Congenita: evidence for neuropathic origin

Brill, S., Sprecher, E., Smith, F. J. D., Geva, N., Gruener, H., Nahman-Averbuch, H. & Defrin, R., Jul 2018, In : British Journal of Dermatology. 179, 1, p. 154-162 9 p.

Research output: Contribution to journalArticle

Open Access
File
Pachyonychia Congenita
Chronic Pain
Hyperalgesia
Foot
Hypesthesia
8 Citations (Scopus)
162 Downloads (Pure)

Clinical and veterinary trypanocidal benzoxaboroles target CPSF3

Wall, R., Rico Vidal, E., Lukac, I., Zuccotto, F., Elg, S., Gilbert, I., Freund, Y. R., Alley, M. R. K., Field, M., Wyllie, S. & Horn, D., 18 Sep 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 38, p. 9616-9621 6 p.

Research output: Contribution to journalArticle

Open Access
File
Trypanosomiasis
Cleavage And Polyadenylation Specificity Factor
Neglected Diseases
African Trypanosomiasis
Messenger RNA
2 Citations (Scopus)
76 Downloads (Pure)

Clinical features and molecular genetic analysis in a Turkish family with oral white sponge nevus

Kürklü, E., Öztürk, Ş., Cassidy, A. J., Ak, G., Koray, M., Çefle, K., Palandüz, Ş., Güllüoğlu, M. G., Tanyeri, H. & McLean, W. H. I., 1 Mar 2018, In : Medicina Oral Patologia Oral y Cirugia Bucal. 23, 2, p. e144-e150 7 p., 21437.

Research output: Contribution to journalArticle

Open Access
File
Keratin-4
Nevus
Porifera
Molecular Biology
Mutation
14 Citations (Scopus)
80 Downloads (Pure)

Codon usage bias controls mRNA and protein abundance in trypanosomatids

Jeacock, L., Correia Faria, J. & Horn, D., 15 Mar 2018, In : eLife. 7, 20 p., e32496.

Research output: Contribution to journalArticle

Open Access
File
Codon
Messenger RNA
Proteins
Genes
Synthetic Genes
14 Citations (Scopus)
60 Downloads (Pure)

Combined drought and heat activates protective responses in eucalyptus globulus that are not activated when subjected to drought or heat stress alone

Correia, B., Hancock, R. D., Amaral, J., Gomez-Cadenas, A., Valledor, L. & Pinto, G., 20 Jun 2018, In : Frontiers in Plant Science. 9, p. 1-14 14 p., 819.

Research output: Contribution to journalArticle

Open Access
File
Eucalyptus globulus
heat stress
water stress
drought
heat
2 Citations (Scopus)
77 Downloads (Pure)

Combined Hyperglycemia and Hyperinsulinemia-induced Insulin Resistance in Adipocytes is associated with Dual Signaling Defects mediated by PKC-ζ

Lu, H., Bogdanovic, E., Yu, Z., Cho, C., Liu, L., Ho, K., Guo, J., Yeung, L. S. N., Lehmann, R., Hundal, H. S., Giacca, A. & Fantus, I. G., 1 Apr 2018, In : Endocrinology. 159, 4, p. 1658-1677 20 p.

Research output: Contribution to journalArticle

Open Access
File
Hyperinsulinism
Adipocytes
Hyperglycemia
Insulin Resistance
Insulin
4 Citations (Scopus)
77 Downloads (Pure)

Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA

Zoltner, M., Krienitz, N., Field, M. C. & Kramer, S., 24 Jul 2018, In : PLoS Neglected Tropical Diseases. 12, 7, p. 1-18 18 p., e0006679.

Research output: Contribution to journalArticle

Open Access
File
Poly(A)-Binding Protein II
Poly(A)-Binding Proteins
Proteomics
Starvation
Messenger RNA
5 Citations (Scopus)

Computational Modelling of Cancer Development and Growth: Modelling at Multiple Scales and Multiscale Modelling

Szymańska, Z., Cytowski, M., Mitchell, E., Macnamara, C. K. & Chaplain, M., 1 May 2018, In : Bulletin of Mathematical Biology. 80, 5, p. 1366-1403 38 p.

Research output: Contribution to journalArticle

growth modeling
Multiscale Modeling
Multiple Scales
Computational Modeling
Growth and Development
4 Citations (Scopus)

Conservation and Variation in Strategies for DNA Replication of Kinetoplastid Nuclear Genomes

Marques, C. A. & McCulloch, R., Feb 2018, In : Current Genomics. 19, 2, p. 98-109 12 p.

Research output: Contribution to journalReview article

Trypanosoma brucei brucei
DNA Replication
Origin Recognition Complex
Genome
Leishmania
8 Citations (Scopus)
86 Downloads (Pure)

Contrasting genetic regulation of plant development in wild barley grown in two European environments revealed by nested association mapping

Herzig, P., Maurer, A., Draba, V., Sharma, R., Draicchio, F., Bull, H., Milne, L., Thomas, W. T. B., Flavell, A. J. & Pillen, K., 16 Mar 2018, In : Journal of Experimental Botany. 69, 7, p. 1517-1531 15 p.

Research output: Contribution to journalArticle

Open Access
File
Plant Development
Hordeum
chromosome mapping
plant development
barley

Correction to: Inhibition of cathepsin B by caspase-3 inhibitors blocks programmed cell death in Arabidopsis

Ge, Y., Cai, Y. M., Bonneau, L., Rotari, V., Danon, A., McKenzie, E. A., McLellan, H., Mach, L. & Gallois, P., 18 Jun 2018, In : Cell Death and Differentiation. 25, 8, p. 1532 1 p.

Research output: Contribution to journalArticle

Open Access
96 Downloads (Pure)

Correction to: A reversible light- and genotype-dependent acquired thermotolerance response protects the potato plant from damage due to excessive temperature

Trapero-Mozos, A., Ducreux, L. J. M., Bita, C. E., Morris, W., Wiese, C., Morris, J. A., Paterson, C., Hedley, P. E., Hancock, R. D. & Taylor, M., Jun 2018, In : Planta. 247, 6, p. 1393-1393 1 p.

Research output: Contribution to journalArticle

Open Access
File
asses
Solanum tuberosum
heat tolerance
Internet
Genotype

Corrigendum to "Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR" [DNA Repair 6 (2007) 1536-1544]

Jowsey, P., Morrice, N. A., Hastie, C. J., MacLauchlan, H., Toth, R. & Rouse, J., May 2018, In : DNA Repair. 65, p. 80 1 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Costs of acquiring phosphorus by vascular land plants: patterns and implications for plant coexistence

Raven, J. A., Lambers, H., Smith, S. E. & Westoby, M., 6 Feb 2018, In : New Phytologist. 217, 4, p. 1420-1427 8 p.

Research output: Contribution to journalReview article

Embryophyta
embryophytes
vascular plants
Phosphorus
Blood Vessels
21 Citations (Scopus)
118 Downloads (Pure)

Critical Research Gaps and Recommendations to Inform Research Prioritisation for More Effective Prevention and Improved Outcomes in Colorectal Cancer

Lawler, M., Alsina, D., Adams, R., Anderson, A., Brown, G., Fearnhead, N. S., Fenwick, S. W., Halloran, S. P., Hochhauser, D., Hull, M. A., Koelzer, V. H., McNair, A. G. K., Monahan, K. J., Nathke, I., Norton, C., Novelli, M., Steele, R., Thomas, A. L., Wilde, L., Wilson, R. H. & 1 others, Tomlinson, I., 1 Jan 2018, In : Colorectal Cancer. 67, 1, p. 179-193 15 p.

Research output: Contribution to journalArticle

Open Access
File
Colorectal Neoplasms
Research
Communication
Pathology
Tumor Microenvironment
6 Citations (Scopus)

Crops, Nitrogen, Water: Are Legumes Friend, Foe, or Misunderstood Ally?

Adams, M. A., Buchmann, N., Sprent, J., Buckley, T. N. & Turnbull, T. L., 1 Jun 2018, In : Trends in Plant Science. 23, 6, p. 539-550 12 p.

Research output: Contribution to journalReview article

nitrogen fixation
legumes
nitrogen
crops
water
123 Citations (Scopus)

Cyanobacterial blooms

Huisman, J., Codd, G. A., Paerl, H. W., Ibelings, B. W., Verspagen, J. M. H. & Visser, P. M., Aug 2018, In : Nature Reviews Microbiology. 16, 8, p. 471-483 13 p.

Research output: Contribution to journalReview article

Cyanobacteria
Eutrophication
Recreation
Fisheries
Climate Change
4 Citations (Scopus)

Cyanobacterial effects in Lake Ludoš, Serbia - Is preservation of a degraded aquatic ecosystem justified?

Tokodi, N., Drobac, D., Meriluoto, J., Lujić, J., Marinović, Z., Važić, T., Nybom, S., Simeunović, J., Dulić, T., Lazić, G., Petrović, T., Vuković-Gačić, B., Sunjog, K., Kolarević, S., Kračun-Kolarević, M., Subakov-Simić, G., Miljanović, B., Codd, G. A. & Svirčev, Z., 1 Sep 2018, In : Science of the Total Environment. 635, p. 1047-1062 16 p.

Research output: Contribution to journalArticle

Aquatic ecosystems
aquatic ecosystem
Lakes
lake
cyanobacterium
19 Citations (Scopus)
112 Downloads (Pure)

Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions

Zeden, M. S., Schuster, C. F., Bowman, L., Zhong, Q., Williams, H. D. & Gründling, A., 2 Mar 2018, In : Journal of Biological Chemistry. 293, 9, p. 3180-3200 21 p.

Research output: Contribution to journalArticle

Open Access
File
Adenosine Monophosphate
Cyclic AMP
Staphylococcus aureus
Growth
Respiration
17 Citations (Scopus)
250 Downloads (Pure)

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Wyllie, S., Thomas, M., Patterson, S., Crouch, S., De Rycker, M., Lowe, R., Gresham, S., Urbaniak, M. D., Otto, T. D., Stojanovski, L., Simeons, F. R. C., Manthri, S., MacLean, L. M., Zuccotto, F., Homeyer, N., Pflaumer, H., Boesche, M., Sastry, L., Connolly, P., Albrecht, S. & 12 others, Berriman, M., Drewes, G., Gray, D. W., Ghidelli-Disse, S., Dixon, S., Fiandor, J. M., Wyatt, P. G., Ferguson, M. A. J., Fairlamb, A. H., Miles, T. J., Read, K. D. & Gilbert, I. H., 9 Aug 2018, In : Nature. 560, 7717, p. 192-197 6 p.

Research output: Contribution to journalArticle

Open Access
File
Visceral Leishmaniasis
Cyclin-Dependent Kinases
Pharmaceutical Preparations
Toxicology
Parasites
2 Citations (Scopus)
65 Downloads (Pure)

Cytoplasmic lattices are not linked to mouse 2-cell embryos developmental arrest

Longo, M., Boiani, M., Redi, C. A. & Monti, M., 24 Sep 2018, In : European Journal of Histochemistry. 62, 4, p. 267-270 4 p.

Research output: Contribution to journalArticle

Open Access
File
cell nucleolus
embryo (animal)
oocytes
mice
cells
3 Citations (Scopus)
97 Downloads (Pure)

Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana

Kovářová, J., Pountain, A. W., Wildridge, D., Weidt, S., Bringaud, F., Burchmore, R. J. S., Achcar, F. & Barrett, M. P., 19 Mar 2018, In : PLoS Pathogens. 14, 3, p. 1-30 30 p., e1006953.

Research output: Contribution to journalArticle

Open Access
File
Leishmania mexicana
Transketolase
Virulence
Enzymes
Pentose Phosphate Pathway
4 Citations (Scopus)

Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity

De Vita, E., Schüler, P., Lovell, S., Lohbeck, J., Kullmann, S., Rabinovich, E., Sananes, A., Heßling, B., Hamon, V., Papo, N., Hess, J., Tate, E. W., Gunkel, N. & Miller, A. K., 11 Oct 2018, In : Journal of Medicinal Chemistry. 61, 19, p. 8859-8874 16 p.

Research output: Contribution to journalArticle

Depsipeptides
Kallikreins
Peptide Hydrolases
Tissue Kallikreins
Enzyme Stability