School of Life Sciences

  • United Kingdom

Research Output 1968 2019

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Meeting abstract
2017
2 Citations (Scopus)

Analogs of the Natural Product Chamuvarinin Target the Trypanosomatid FoF1-ATP Synthase Mitochondrial Complex V

Menzies, S. K., Tulloch, L. B., Fraser, A. L., Gould, E. R., King, E. F., Zacharova, M. K., Florence, G. J. & Smith, T. K., 2017, In : American Journal of Tropical Medicine and Hygiene. 95, 5 Supplement, p. 164 1 p., 520.

Research output: Contribution to journalMeeting abstract

Mitochondrial Proton-Translocating ATPases
Triazoles
Biological Products
Acetogenins
Adenosine Triphosphate

Early stages of Parkin activation - A computational study

Carvalheda Dos Santos, C., Bueren-Calabuig, J., Kumar, A., Walden, H. & Pisliakov, A., 2017, In : European Biophysics Journal. 46, Suppl 1, p. S155 1 p., P-154.

Research output: Contribution to journalMeeting abstract

Mitochondrial Degradation
Phosphorylation
Allosteric Regulation
Ubiquitin-Conjugating Enzymes
Mutation

Ultrasound imaging of the epidural space at different depths in a porcine model

Chandra, A., Demore, C., Corner, G., Munirama, S. & McLeod, G., Aug 2017, In : British Journal of Anaesthesia. 119, 2, p. E16-E17 2 p.

Research output: Contribution to journalMeeting abstract

2016

Antagonism of Wnk/Hsn2 kinase ameliorates neuropathic pain by reducing maladaptive KCC2 inhibitory phosphorylation after nerve injury

Kahle, K., Schmouth, J-F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Dion, P. A., Duan, J., Woolf, C. J., Inquimbert, P. & Rouleau, G. A., Apr 2016, In : Journal of Neurosurgery. 124, 4, p. A1194-A1195 2 p., 800.

Research output: Contribution to journalMeeting abstract

2014
56 Downloads (Pure)

ChemicalToolBoX and its application on the study of the drug like and purchasable space

Lucas, X., Grüning, B. A. & Günther, S., 11 Mar 2014, In : Journal of Cheminformatics. 6, Suppl. 1, 1 p., P51.

Research output: Contribution to journalMeeting abstract

Open Access
File
2013

A nonsense mutation in the mattrin gene causes the matted mouse phenotype and is a predisposing gene for atopic dermatitis in humans

Goh, C. S., Saunders, S. P., Cole, C., Weidinger, S., Baurecht, H., Lee, Y., Reynolds, N. J., Barker, J. N., Cordell, H. J., Brown, S. J., Irvine, A. D., McLean, I., Sandilands, A. & Fallon, P. G., 2013, In : Journal of Investigative Dermatology. 133, S1, p. S145 1 p., 854.

Research output: Contribution to journalMeeting abstract

42 Citations (Scopus)

Birt-hogg-dube syndrome is a novel ciliopathy

Luijten, M., Claessens, T., Basten, S., Vernooij, M., Menko, F., Nookala, R., Scott, C., van Geel, M., Janssen, R., Easton, J., Vreeburg, M., Kamps, M., Land, S., Tee, A., Giles, R., Coull, B. & van Steensel, M., 2013, In : Journal of Investigative Dermatology. 133, S1, p. S136 1 p., 800.

Research output: Contribution to journalMeeting abstract

50 Citations (Scopus)

Clouston syndrome caused by a heterozygous mutation in connexin 30, resembling pachyonychia congenita

Hale, G., Wilson, N., Smith, F. & Zamiri, M., Jul 2013, In : British Journal of Dermatology. 169, Suppl. 1, p. 33-33 1 p., P31.

Research output: Contribution to journalMeeting abstract

Degradation characteristics of the major PML isoforms in response to arsenic

Hands, K. J., Cuchet-Lourenco, D., Everett, R. D. & Hay, R. T., Apr 2013, In : British Journal of Haematology. 161, Suppl. 1, p. 17 1 p., 35.

Research output: Contribution to journalMeeting abstract

Erratum: Comparison of effects of biguanide and diguanidine antihyperglycaemic drugs on cell signalling responses

Bacon, S., Harthill, J., Coats, J., Stewart, D., McDougall, G. & Rena, G., Jan 2013, In : Diabetic Medicine. 30, 1, p. 130 1 p.

Research output: Contribution to journalMeeting abstract

6 Citations (Scopus)

Expanding the phenotypic spectrum of Olmsted Syndrome

Wilson, N. J., Cole, C., Milstone, L. M., Hansen, C. D., Schwartz, M. E., McLean, W. H. & Smith, F. J., 2013, In : Journal of Investigative Dermatology. 133, S1, p. S144 1 p., 847.

Research output: Contribution to journalMeeting abstract

Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K., Mar 2013, In : Diabetic Medicine. 30, Suppl. 1, p. E2-E2 1 p., P577.

Research output: Contribution to journalMeeting abstract

How does glucophage (metformin) work? Investigation of the cellular action of chemical analogues

Logie, L., Bacon, S., Middleton, P., Harthill, J., Coats, J., Stewart, D., Sakamoto, K., McDougall, G. & Rena, G., Mar 2013, In : Diabetic Medicine. 30, Suppl. 1, p. 41-41 1 p., P44.

Research output: Contribution to journalMeeting abstract

Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

Nardi, F., Lipina, C., Magill, D. & Hundal, H. S., Mar 2013, In : Diabetic Medicine. 30, Suppl. 1, p. 49-49 1 p., P70.

Research output: Contribution to journalMeeting abstract

The system L1 amino acid transporter (SLC7A5) facilitates nutrient signalling in mouse skeletal muscle in vivo

Poncet, N. & Taylor, P. M., Apr 2013, In : FASEB Journal. 27, Suppl., 1 p., 350.4.

Research output: Contribution to journalMeeting abstract

2012

AKT independent glioma suppression by PTEN

Zilidis, G., Tibarewal, P., Spinelli, L. & Leslie, N. R., Sep 2012, In : Journal of Neuro-Oncology. 14, p. 8-8 1 p.

Research output: Contribution to journalMeeting abstract

Comparison of effects of biguanide and diguanidine antihyperglycaemic drugs on cell signalling responses

Bacon, S., Harthill, J., Coates, J., Stewart, D., McDougall, G. & Rena, G., 2012, In : Diabetic Medicine. 29, Suppl. 1, p. 41 1 p., P41.

Research output: Contribution to journalMeeting abstract

Impact of Anthocyanin chemical structure found in pomegranate juice on leukaemia treatment

Dahlawi, H., Jordan-Mahy, N., Clench, M. R., McDougall, G. J. & Le Maitre, C., Sep 2012, In : Journal of Pathology. 228, Suppl. 1, p. S37-S37 1 p.

Research output: Contribution to journalMeeting abstract

Neural responses to rewards and punishments in patients with opiate dependence on methadone treatment: fNEMO study

Gradin, V., Gray, S., MacFarlane, J., Waiter, G., Balfour, D., Matthews, K., Baldacchino, A. & Steele, D., Oct 2012, In : European Neuropsychopharmacology. 22, Suppl 2, p. S402-S403 2 p., P.6.c.008.

Research output: Contribution to journalMeeting abstract

System L amino acid transporter 1 (slc7a5) expression is crucial for T cell blastogenesis

Sinclair, L. V., Taylor, P. M. & Cantrell, D. A., Sep 2012, In : Immunology. 137, s1, p. 347-347 1 p.

Research output: Contribution to journalMeeting abstract

The anti-cancerous potential of polyphenols in the treatment of human myeloid and lymphoid leukaemia

Mahbub, A., Le Maitre, C., Haywood-Small, S. L., McDougall, G., Cross, N. A. & Jordan-Mahy, N., Sep 2012, In : Journal of Pathology. 228, Suppl. 1, p. S34-S34 1 p.

Research output: Contribution to journalMeeting abstract

The control of cell energy metabolism by NF-j B transcription factors

Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S. & Franzoso, G., Sep 2012, In : Immunology. 137, S1, p. 19 1 p.

Research output: Contribution to journalMeeting abstract

2011
35 Citations (Scopus)

Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: implications for NO synthase 2 expression

Lopez Pelaez, M., Soria-Castro, I., Bosca, L., Fernandez, M. & Alemany, S., 2011, In : Immunology. 135, S1, p. 105 1 p., 613.

Research output: Contribution to journalMeeting abstract

Drug discovery initiative at the University of Dundee: hit-to-lead development for hat and generation of chemical tools

Grimaldi, R., Urich, R., Sienkiewicz, N., Woodland, A., Urbaniak, M. D., Mathieson, T., Eberhard, D., Bantscheff, M., Drewes, G., Ferguson, M. A. J., Gilbert, I. H., Frearson, J. A., Wyatt, P. G. & Fairlamb, A. H., 2011, In : Tropical Medicine & International Health. 16, S.1, p. 212 1 p., 1.3-148.

Research output: Contribution to journalMeeting abstract

Homozygosity of dominant missense mutations in keratin 17 leads to alopecia in addition to severe pachyonychia congenita

Wilson, N. J., Hansen, C. D., Cardenas Perez, M. L., Vahlquist, A., Schwartz, M. E. & Smith, F. J., 2011, In : Journal of Investigative Dermatology. 131, S1, p. S67 1 p., 402.

Research output: Contribution to journalMeeting abstract

On the hunt for new diagnostic antigens for human African trypanosomiasis

Sullivan, L., Carrington, M. & Ferguson, M. A. J., Oct 2011, In : Tropical Medicine & International Health. 16, p. 201-201 1 p.

Research output: Contribution to journalMeeting abstract

16 Downloads (Pure)

Robust neutralising activity and activation of neutrophil cytotoxic responses mediated by antibodies targeting the HTLV-1 envelope glycoprotein

Kuo, C., Tulloch, L. & Brighty, D. W., 6 Jun 2011, In : Retrovirology. 8, Supplement 1, 1 p., A170.

Research output: Contribution to journalMeeting abstract

Open Access
File
2010

Activating K-Ras mutations outwith "hotspot" codons in sporadic colorectal tumours: implications for personalised cancer medicine

Smith, G., Bounds, R., Wolf, H., Pratt, N., Carey, F., Steele, R. & Wolf, C., Sep 2010, In : Journal of Pathology. 222, S1, p. S12-S12 1 p.

Research output: Contribution to journalMeeting abstract

Cancer metabolism as a potential treatment target

Hardie, G., 2010, In : Annals of Oncology. 21, Suppl. 4, p. iv21-iv21 1 p., 3IN.

Research output: Contribution to journalMeeting abstract

Glycoinositolphosphorylceramide from Pathogenic Fungus Sporothrix schenckii Shows That Fatty Acid Hydroxylation Level Correlates with the Mycelium-Yeast Thermal-Induced Morphological Transition

Medeiros, A., Bandini, G., Macedo, C., Ferguson, M., Kirsch, S., Soltwisch, J., Previato, J., Mendonca-Previato, L. & Peter-Katalinic, J., Nov 2010, In : Glycobiology. 20, 11, p. 1506-1506 1 p.

Research output: Contribution to journalMeeting abstract

Investigating the regulatory role of GAGs in early neural differentiation of mouse embryonic stem cells

Johnson, C. E., Holley, R. J., Rushton, G., Stavridis, M. P., Gallagher, J. T., Ward, C. M. & Merry, C. L. R., Dec 2010, In : International Journal of Experimental Pathology. 91, 6, p. A36-A37 2 p.

Research output: Contribution to journalMeeting abstract

Notch activity is essential for sequential segmentation

Maroto, M., Ferjentsik, Z. & Dale, J. K., 1 Aug 2010, In : Developmental Biology. 344, 1, p. 466-466 1 p.

Research output: Contribution to journalMeeting abstract

6 Citations (Scopus)

PTEN and Cancer

Leslie, N., Sep 2010, In : Journal of Pathology. 222, S1, p. S2-S2 1 p.

Research output: Contribution to journalMeeting abstract

Regulation of mammary epithelial architecture by PTEN

Lim, J. C., Davidson, L., Weerasinghe, N. R., Zilidis, G., Tibarewal, P., Spinelli, L. & Leslie, N. R., 2010, In : Breast Cancer Research. 12, p. S3-S3 1 p., P4.

Research output: Contribution to journalMeeting abstract

2009

A requirement for GDP-L-fucose in Leishmania inferred by rescue of D-arabinopyranose/L-fucose salvage mutants (Fkp40(-)/Afkp80(-)) by expression of GDP-L-fuc synthetic enzymes

Guo, H., Novozhilova, N. M., Bandini, G., Notton, T., Turco, S. J., Ferguson, M. A. J. & Beverley, S. M., Nov 2009, In : Glycobiology. 19, 11, p. 1297-1297 1 p.

Research output: Contribution to journalMeeting abstract

Chaperone-signal peptide interactions on the Tat protein transport pathway

Coulthurst, S. J. & Sargent, F., Jul 2009, In : FEBS Journal. 276, Suppl. 1, p. 3-3 1 p., PL9.

Research output: Contribution to journalMeeting abstract

How does human O-Glcnacase recognize O-Glcnacylated protein substrates?

Schimpl, M., Borodkin, V. S. & Van Aalten, D. M. F., 2009, In : Glycobiology. 19, 11, p. 1369-1369 1 p., 272.

Research output: Contribution to journalMeeting abstract

Mechanisms regulating differentiation onset in the embryonic axis and ES cells

Collins, B. J., Olivera-Martinez, I., Stavridis, M. P. & Storey, K. G., Aug 2009, In : Mechanisms of Development. 126, p. S29-S29 1 p.

Research output: Contribution to journalMeeting abstract

3 Citations (Scopus)

Passing GO (gene ontology) in plant pathogen biology: a report from the Xanthomonas genomics conference

Ryan, R. P., Koebnik, R., Szurek, B., Boureau, T., Bernal, A., Bogdanove, A. & Dow, J. M., 1 Dec 2009, In : Cellular Microbiology. 11, 12, p. 1689-1696 8 p.

Research output: Contribution to journalMeeting abstract

Preferential Activation of TLR2/6 Heterodimer by Synthetic Trypanosoma Cruzi Trypomastigote Glycosylphosphatidylinositols is Enhanced by Coexpression of CD14 and CD36

Nohara, L., Yashunsky, D., Ferguson, M., Nikolaev, A. & Almeida, I., Nov 2009, In : Glycobiology. 19, 11, p. 1361-1361 1 p., 247.

Research output: Contribution to journalMeeting abstract

2008

Identification of small compounds that mimic insulin action on the transcription factor FOXO1a

Cameron, A., Anton, S., Reetoo, N., Melville, L., Houston, N., Dayal, S., McDougall, G., Stewart, D. & Rena, G., 2008, In : Diabetes. 57, Suppl., p. A699-A700 2 p.

Research output: Contribution to journalMeeting abstract

Sugar nucleotide metabolism and compartmentation in Trypanosoma brucei: new insights from UDP-GlcNAc and UDP-Glc biosynthesis

Marino, K., Guther, M. L. S. & Ferguson, M., Nov 2008, In : Glycobiology. 18, 11, p. 946-946 1 p.

Research output: Contribution to journalMeeting abstract

2007

Single-molecule fluorescence microscopy of the twin-arginine translocation (Tat) system

Leake, M. C., Greene, N. P., Godun, R. M., Palmer, T., Berry, R. M. & Berks, B. C., 2007, In : Biophysical Journal. 92, Suppl., p. 527A-527A 1 p.

Research output: Contribution to journalMeeting abstract

2006

The proteome of Trypanosoma cruzi shed vesicles involved in host immuno modulation and cell invasion

Nakayasu, E. S., Torrecilhas, A. C. T., Gozzo, F., Nohara, L. L., Lamont, D., Alves, M. J. M., Ferguson, M. A. J. & Almeida, I. C., 2006, In : FASEB Journal. 20, 4, p. A514-A514 1 p., 346.5.

Research output: Contribution to journalMeeting abstract

2005

14-3-3 Phosphoproteomics for linking signalling pathways to cellular processes

MacKintosh, C., Harthill, J. & Kulma, A., Jul 2005, In : Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 141, 3, p. S250-S250 1 p.

Research output: Contribution to journalMeeting abstract

14-3-3s as signalling integrators in plant and human cells

MacKintosh, C., Pozuelo-Rubio, M., Geraghty, K., Wong, B., Wood, N., Murphy, J., Dubois, F. . & Harthill, J., 2005, In : FEBS Journal. 272, Suppl. 1, p. 460-461 2 p., J4-004.

Research output: Contribution to journalMeeting abstract

Isolation of 14-3-3 binding proteins from Hydra

Pauly, B. S., Stiening, B., MacKintosh, C., Rudd, S., David, C. N. & Bottger, A., 2005, In : European Journal of Cell Biology. 84, Suppl. 1, p. 37-37 1 p., S2-32.

Research output: Contribution to journalMeeting abstract

2004

Dissection of nonhost resistance of Arabidopsis to Phytophthora infestans

Huitema, E., Dong, S., Hamada, W. & Kamoun, S., 2004, In : Phytopathology. 94, 6, p. S159 1 p.

Research output: Contribution to journalMeeting abstract