School of Life Sciences

  • United Kingdom

Research Output 1968 2020

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Book/Film/Article review

What pharmacological resources to use to activate AMPK? AICAR, metformin or A-769662, a new AMPK activator

Translated title of the contribution: Quels outils pharmacologiques utiliser pour activer l’AMPK ? AICAR, metformine ou A-769662, un nouvel activateur de l’AMPKViollet, B., Foretz, M., Leclerc, J., Hardie, G. & Sakarmoto, K., Mar 2008, In : Diabetes & Metabolism. 34, s3, p. H23 2 p.

Research output: Contribution to journalBook/Film/Article review

36 Citations (Scopus)

Visceral leishmaniasis and arsenic: an ancient poison contributing to antimonial treatment failure in the Indian subcontinent?

Perry, M., Wyllie, S., Prajapati, V. K., Feldmann, J., Sundar, S., Boelaert, M. & Fairlamb, A. H., Oct 2011, In : Tropical Medicine & International Health. 16, S1, p. 66-67 2 p.

Research output: Contribution to journalBook/Film/Article review

Using molecular phylogeny to investigate the bacteria associated with the cabbage aphid (Brevicoryne brassicae)

Clark, E. L., Karley, A. J., Wishart, J., Daniell, T. J. & Hubbard, S. F., Jun 2009, In : Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 153, 2; Suppl., p. S47-S47 1 p., CSS.17.

Research output: Contribution to journalBook/Film/Article review

Uranium stability in near-surface environments: Lessons from the study of depleted uranium munitions

Vaughan, D. J., Alvarez, R., Bryan, N. D., Fomina, M., Gadd, G. M., Handley-Sidhu, S., Keith-Roach, M. J., Livens, F. R. & Lloyd, J. R., 2009, In : Geochimica et Cosmochimica Acta. 73, 13, p. A1375 1 p.

Research output: Contribution to journalBook/Film/Article review

Tumour microenvironment is implicated by dermal fibroblast expression profiling in the development of aggressive squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa

Ng, Y. Z., Pourreyron, C., Salas-Alanis, J. C., Murrell, D. F., McGrath, J. A., Lane, E. B., Leigh, I. & South, A., Sep 2010, In : Journal of Investigative Dermatology. 130, p. S83-S83 1 p.

Research output: Contribution to journalBook/Film/Article review

48 Citations (Scopus)

Translocated oomycete effectors that target the plant immune system

Birch, P. R. J., Whisson, S., Boevink, P., Armstrong, M., Gilroy, E., Pritchard, L., Grouffaud, S., Sandanandom, A., Taylor, R., Kamoun, S. & Bos, J., Jul 2008, In : Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 150, 3, p. S176-S177 2 p.

Research output: Contribution to journalBook/Film/Article review

The potential use of temperate chimeric phages in arthropod vectored disease control

Butcher, R., Karr, T. L., Hubbard, S. F. & Areekul-Butcher, B., Jul 2008, In : Infection, Genetics and Evolution. 8, 4, p. S30-S31 2 p., 62.

Research output: Contribution to journalBook/Film/Article review

6 Citations (Scopus)

The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development

Reis, B., Finkenstaedt, D., Finlay, D. K., Cantrell, D. A., Pfeffer, K. & Beer, S., Aug 2008, In : Wiener Klinische Wochenschrift. 120, Supplement 1, p. 20-20 1 p., 057.

Research output: Contribution to journalBook/Film/Article review

The impact of dedicated dermatology services on the awareness of cutaneous cancer risk and on attitudes towards UV exposure among transplant recipients

Casabonne, D., Newton, R., Ismail, F., Mitchell, L., Lally, A., Imko-Walczuk, B., Wojnarowska, F., Proby, C. & Harwood, C., Aug 2011, In : Journal of Epidemiology and Community Health. 65, p. A107-A107 1 p.

Research output: Contribution to journalBook/Film/Article review

The effect of SUMO modification on hepatic differentiation from hESCs

Hannoun, Z., Jaffray, E., Greenhough, S., Wilmut, I., Iredale, J. P., Hay, R. T. & Hay, D. C., 30 Dec 2010, In : Toxicology. 278, 3, p. 352-352 1 p.

Research output: Contribution to journalBook/Film/Article review

The developmental mutant talpid(3) lacks primary cilia

Bangs, F., Yin, Y., Paton, R., Prescott, A., James, J., Davey, M., Whitley, P., Genikhovich, G., Technau, U., Briscoe, J., Burt, D. & Tickle, C., Aug 2009, In : Mechanisms of Development. 126, p. S262-S262 1 p.

Research output: Contribution to journalBook/Film/Article review

Targetes gene regulation mediated by nucleolar snoRNAs

Ono, M., Scott, M., Yamada, K., Barton, G., Hutvagner, G. & Lamond, A., Jun 2008, In : FEBS Journal. 275, S1, p. 73-73 1 p.

Research output: Contribution to journalBook/Film/Article review

Synthetic approaches to cyclic peptide natural products as chitinase inhibitors

Dixon, M., Giuntini, F., Nathubhai, A., Andersen, O., van Aalten, D. & Eggleston, I., Aug 2008, In : Journal of Peptide Science. 14, S1, p. 55-55 1 p., P10102-031.

Research output: Contribution to journalBook/Film/Article review

Synthesis of cyclic peptide chitinase inhibitors: natural products,with chemotherapeutic potential

Dixon, M., Nathubhai, A., Andersen, O., van Aalten, D. & Eggleston, I., Aug 2008, In : Journal of Peptide Science. 14, S1, p. 13-13 1 p., S02-4.

Research output: Contribution to journalBook/Film/Article review

Structured-illumination microscopy of living cells

Gustafsson, M. G. L., Kner, P., Chhun, B. B. & Griffis, E. R., 16 Aug 2009, In : Abstracts of Papers of the American Chemical Society. 238, 1 p.

Research output: Contribution to journalBook/Film/Article review

Steatocystoma multiplex and persistent primary dentition due to a novel keratin 17 mutation

Gass, J. K., Wilson, N. J., Smith, E. B. F., Lane, B., McLean, W. H. I., Salvary, I. & Burrows, N. P., 2008, In : British Journal of Dermatology. 159, S1, p. 119 1 p., PA-13.

Research output: Contribution to journalBook/Film/Article review

Siglec-E is a negative regulator of acute pulmonary neutrophil recruitment induced by LPS

McMillan, S. J., Cao, P., Richards, H. & Crocker, P. R., Dec 2010, In : Immunology. 131, s1, p. 72-72 1 p., 153.

Research output: Contribution to journalBook/Film/Article review

Sensing of energy availability by the AMP-activated protein kinase

Hardie, D. G. & McBride, A., 2009, In : Journal of Physiological Sciences. 59, p. 61-61 1 p.

Research output: Contribution to journalBook/Film/Article review

Sensing and signaling functions associated with the SNAT2 amino acid transporter

Hundal, H., Cwiklinski, E. & Taylor, P. M., Jul 2009, In : Amino Acids. 37, Suppl. 1, p. S8 1 p.

Research output: Contribution to journalBook/Film/Article review

3 Citations (Scopus)

Role of chromatin remodeling enzymes in the cellular response to hypoxia

Melvin, A., Kenneth, N., Mudie, S. & Rocha, S., 2009, In : International Journal of Molecular Medicine. 24, p. S23-S23 1 p.

Research output: Contribution to journalBook/Film/Article review

Reactive Oxygen Species increases Intracellular Calcium, alters the Electrophysiological Properties and Synaptic Transmission In Intrinsic Cardiac Ganglion Neurons: in vitro

Dyavanapalli, J., Rimmer, K. & Harper, A. A., 28 Oct 2008, In : Circulation. 118, 18, p. S359-S359 1 p., 1623.

Research output: Contribution to journalBook/Film/Article review

Quantitative Analysis of Proteome Localisation and Dynamics

Lamond, A., Aug 2009, In : Molecular & Cellular Proteomics. 8, 8; suppl. 1, p. S26-S26 1 p., 3.1.

Research output: Contribution to journalBook/Film/Article review

QUANTITATIVE ANALYSIS OF CHROMATIN HIGHER-ORDER ORGANIZATION IN LIVING CELLS

Lieres, D., Visvanathan, A., James, J., Swift, S. & Lamond, A. I., 2009, In : Cellular Oncology. 31, 2, p. 121-121 1 p., P22.

Research output: Contribution to journalBook/Film/Article review

Protein dynamics in the cell nucleus

Lamond, A., Boivert, F. M., Ono, M., Trinkle-Mulcahy, L., Koningsbruggen, S. V., Lleres, D., Andersen, J. & Mann, M., Jun 2008, In : FEBS Journal. 275, Suppl. 1, p. 8-8 1 p., IL 1C-5.

Research output: Contribution to journalBook/Film/Article review

PolySUMO chains target proteins for degradation

Geoffroy, M. -C., Tatham, M. H., Shen, L., Plechanovova, A., Hattersley, N., Jaffray, E. G. & Hay, R. T., Jul 2009, In : Journal of Neurochemistry. 110, p. 32-32 1 p.

Research output: Contribution to journalBook/Film/Article review

Phenotype and genotype of a patient with McLeod syndrome

Sammler, E., O'Riordan, J., Swingler, R., Poole, J. & Hormuzdi, S. G., Apr 2009, In : Journal of Neurology, Neurosurgery and Psychiatry. 80, 4, p. 456-456 1 p., CP4.

Research output: Contribution to journalBook/Film/Article review

O-Glcnacylation of TAB1 modulates TAK1-mediated cytokine release

Pathak, S., Campbell, D., Ibrahim, A. & Van Aalten, D. M. F., Nov 2010, In : Glycobiology. 20, 11, p. 1478-1478 1 p., 92.

Research output: Contribution to journalBook/Film/Article review

O-Glcnacase substrate recognition involves both sugar and protein

Schimpl, M., Schuettelkopf, A., Borodkin, V. S. & Van Aalten, D. M. F., Nov 2010, In : Glycobiology. 20, 11, p. 1481-1481 1 p., 101.

Research output: Contribution to journalBook/Film/Article review

43 Citations (Scopus)

Neurogenesis, mitosis and centrosome: the role of DYRK1A

Ferrandl, A. I., Storey, K. G. & Swedlow, J. R., Aug 2009, In : Mechanisms of Development. 126, Supplement, p. S128-S128 1 p., 06-P028.

Research output: Contribution to journalBook/Film/Article review

Mechanisms of action of ceramide in different muscle cell lines

Translated title of the contribution: Mécanismes d’action des céramides dans différentes lignées de cellules musculairesKhoury, R., Turban, S., Loiseau, N., Stretton, C., Lasnier, F., Hundal, H., Ferre, P. & Hajduch, E., Mar 2011, In : Diabetes & Metabolism. 37, s1, p. A30-A30 1 p., P027.

Research output: Contribution to journalBook/Film/Article review

Lymphoblasts produce a lysosomal protease that rapidly degrades L-asparaginase-implications for therapy in childhood acute lymphoblastic leukemia

Patel, N., Krishnan, S., Offman, M. N., Moss, C. X., Ariffin, H., Vandelft, F. W., Yiannikouris, O., Leighton, C., Alexander, S., Holland, M., Khater, D., Liu, J. Z., Essink, M., Bates, P., Watts, C. & Saha, V., 16 Nov 2007, In : Blood. 110, 11, p. 821A-821A 1 p.

Research output: Contribution to journalBook/Film/Article review

Keratin K6c mutations cause focal keratoderma

Wilson, N. J., Messenger, A. G., Leachmin, S. A., Lane, E. B., McLean, W. & Smith, F. J., Apr 2008, In : Journal of Investigative Dermatology. 128, p. S127-S127 1 p., Abstract 757.

Research output: Contribution to journalBook/Film/Article review

Investigating the role of murine siglec-E in the modulation of TLR responses and susceptibility to infection

McKenzie, E. J., Richards, H. E., Zhang, J. Q., Mastroeni, P. & Crocker, P. R., Dec 2010, In : Immunology. 131, s1, p. 82-82 1 p., 204.

Research output: Contribution to journalBook/Film/Article review

Hit to lead and lead optimization of novel small molecules for the treatment of human African trypanosomiasis

Freeman, J. C., Perales, J. B., Woodland, A., Bacchi, C. J., Bowling, T. S., Cleghorn, L., Gamon, C. G., Grimaldi, R., Hauser, D., Mercer, L. T., Nare, B., Nguyen, T. M., Noe, R. A., Rewerts, C. E., Wring, S. A., Wyatt, P. G., Yarlett, N. R., Jacobs, R. T. & Don, R., 16 Aug 2009, In : Abstracts of Papers of the American Chemical Society. 238, p. - 1 p.

Research output: Contribution to journalBook/Film/Article review

HIF-1alpha is a novel target of the SWI/SNF chromatin remodelling complex

Rocha, S., Kenneth, N. S., van Uden, P. & Mudie, S., Jul 2008, In : EJC Supplements. 6, 9, p. 90-90 1 p., 352.

Research output: Contribution to journalBook/Film/Article review

hExo70, a subunit of the exocyst complex -: a possible link between vesicular transport, pre-mRNA splicing and aging?

Dellago, H., Grillari, J., Löscher, M., Ajuh, P., Ritter, G., Eisenhaber, F., Lamond, A. & Katinger, H., 2009, In : Experimental Gerontology. 44, 1-2, p. 128-128 1 p.

Research output: Contribution to journalBook/Film/Article review

GPIomics: Global Analysis of Glycosylphosphatidylinositol (GPI)-Anchored Molecules of Trypanosoma cruzi by Tandem Mass Spectrometry

Nakayasu, E. S., Yashunsky, D. V., Nohara, L. L., Torrecilhas, A. C. T., Nikolaev, A. V. & Almeida, I. C., Nov 2008, In : Glycobiology. 18, 11, p. 974-974 1 p., 140.

Research output: Contribution to journalBook/Film/Article review

Global view of nucleolar protein dynamics for P14ARF tumor suppressor signaling

Yamada, K., Ono, M., Rocha, S., Perkins, N. & Lamond, A., Jun 2008, In : FEBS Journal. 275, Suppl. 1, p. 143-143 1 p., PP2B-36.

Research output: Contribution to journalBook/Film/Article review

13 Citations (Scopus)

Geochemical and microbial controls of the decomposition and dispersion of depleted Uranium in the environment: Experimental studies

Vaughan, D. J., Alvarez, R., Bryan, N., Fomina, A., Gadd, G. M., Handley-Sidhu, S., Keith-Roach, M. J., Livens, F. R. & Lloyd, J. R., 2008, In : Geochimica et Cosmochimica Acta. 72, 12 Supplement, p. A978 1 p.

Research output: Contribution to journalBook/Film/Article review

Extracellular matrix composition in dermal microenvironment is implicated in development of life threatening cutaneous squamous cell carcinoma

Ng, Y. Z., Pourreyron, C., Salas-Alanis, J. C., Murrell, D. F., McGrath, J. A., Lane, E. B. & South, A. P., Sep 2011, In : Journal of Investigative Dermatology. 131, p. S32-S32 1 p., 190.

Research output: Contribution to journalBook/Film/Article review

Evidence for Direct Cross-Talk between Two Essential Nutrient-Sensing Enzymes: O-GlcNAc Transferase (OGT) and AMP-activated Kinase (AMPK)

Bullen, J., Balsbaugh, J., Neumann, D., Hardie, G., Shabanowitz, J., Hunt, D. & Hart, G., Nov 2011, In : Glycobiology. 21, 11, p. 1487-1487 1 p.

Research output: Contribution to journalBook/Film/Article review

31 Citations (Scopus)

Disordered insulin secretion in the development of insulin resistance and Type 2 diabetes

Schofield, C. J. & Sutherland, C., 2012, In : Diabetic Medicine. 29, 8, p. 972-979 8 p.

Research output: Contribution to journalBook/Film/Article review

Type 2 Diabetes Mellitus
Insulin Resistance
Insulin
Hyperglycemia
Epidemiologic Studies

Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator

Lain, S., Hollick, J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K., Thompson, A., Mathers, J., Holland, S., Stark, M. J. R., Lane, D. & Westwood, N. J., Dec 2007, In : Molecular Cancer Therapeutics. 6, 12, p. 3476S-3477S 2 p.

Research output: Contribution to journalBook/Film/Article review

Developing small molecule drugs to rescue nonsense mutations in disease-causing genes

Nomura, T., Gartner, U., McElroy, S., Torrie, L., Pourreyron, C., South, A. P., Wood, G., Woodland, A., Frearson, J., Wyatt, P. & McLean, I., Apr 2011, In : Journal of Investigative Dermatology. 131, p. S67-S67 1 p., 397.

Research output: Contribution to journalBook/Film/Article review

Dermal fibroblast expression profiling implicates tumour microenvironment in the development of aggressive squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa

Ng, Y. Z., Pourreyron, C., Proby, C., Salas, J., Murrell, D. F., McGrath, J. A., Lane, E. B., Leigh, I. M. & South, A. P., Apr 2010, In : British Journal of Dermatology. 162, 4, p. 948-948 1 p.

Research output: Contribution to journalBook/Film/Article review

C-terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA

Grosskinsky, U., Oberhettinger, P., Schuetz, M., Ruiz-Perez, F., Donald, J., Palmer, T., Henderson, I. R. & Autenrieth, I. B., Sep 2009, In : International Journal of Medical Microbiology. 299, p. 62-63 2 p., MPP72.

Research output: Contribution to journalBook/Film/Article review

Copy number variation within the filaggrin gene contributes to risk of atopic dermatitis

Brown, S. J., Kroboth, K., Sandilands, A., Campbell, L. E., Pohler, E., Irvine, A. D., Cordell, H. J. & McLean, W., Apr 2011, In : Journal of Investigative Dermatology. 131, Supplement 1, p. S63-S63 1 p., 375.

Research output: Contribution to journalBook/Film/Article review

Circulating neopterin and monocyte chemoattractant protein-1 are responsive to statin therapy but are poor predictors of cardiovascular events in type 2 diabetes in CARDS

Colhoun, H. M., Betteridge, D. J., Durrington, P. N., Hitman, G., Neil, H. A. W., Charlton-Menys, V., Bao, W., DeMicco, D., Preston, G., Livingstone, S. & Fuller, J. H., Sep 2009, In : Diabetologia. 52, Supplement 1, p. S481-S481 1 p., 1247.

Research output: Contribution to journalBook/Film/Article review

CARB 22-GPI anchors: WHY and HOW the complex molecules are being synthesized

Nikolaev, A. V., 16 Aug 2009, In : Abstracts of Papers of the American Chemical Society. 238, p. - 1 p.

Research output: Contribution to journalBook/Film/Article review