School of Life Sciences

  • United Kingdom

Research Output 1968 2020

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Letter
1 Citation (Scopus)
6 Downloads (Pure)

Painful punctate palmoplantar keratoderma due to heterozygous mutations in AAGAB

Zamiri, M., Wilson, N. J., Mackenzie, A., Sobey, G., Leitch, C. & Smith, F. J. D., 19 Nov 2018, In : The British journal of dermatology. 7 p.

Research output: Contribution to journalLetter

Open Access
File
Palmoplantar Keratoderma
Mutation
Genes
Weight-Bearing
Carrier Proteins
1 Citation (Scopus)
98 Downloads (Pure)

Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment

Roekevisch, E., Leeflang, M. M. G., Schram, M. E., Campbell, L. E., Irwin McLean, W. H., Kezic, S., Bos, J. D., Spuls, P. I. & Middelkamp-Hup, M. A., 8 Jan 2018, In : British Journal of Dermatology. 177, 6, p. 1745-1746 2 p.

Research output: Contribution to journalLetter

Open Access
File
Atopic Dermatitis
Immunosuppressive Agents
Mutation
Randomized Controlled Trials
Therapeutics
240 Citations (Scopus)

Piezo1 integration of vascular architecture with physiological force

Li, J., Hou, B., Tumova, S., Muraki, K., Bruns, A., Ludlow, M. J., Sedo, A., Hyman, A. J., McKeown, L., Young, R. S., Yuldasheva, N. Y., Majeed, Y., Wilson, L. A., Rode, B., Bailey, M. A., Kim, H. R., Fu, Z., Carter, D. A. L., Bilton, J., Imrie, H. & 8 others, Ajuh, P., Dear, T. N., Cubbon, R. M., Kearney, M. T., Prasad, K. R., Evans, P. C., Ainscough, J. F. X. & Beech, D. J., 13 Nov 2014, In : Nature. 515, 7526, p. 279-82 4 p.

Research output: Contribution to journalLetter

Blood Vessels
Endothelial Cells
Calcium
Haploinsufficiency
Cell Polarity
360 Citations (Scopus)

Prediction of protein secondary structure and active sites using the alignment of homologous sequences

Zvelebil, M. J., Barton, G. J., Taylor, W. R. & Sternberg, M. J. E., 20 Jun 1987, In : Journal of Molecular Biology. 195, 4, p. 957-961 5 p.

Research output: Contribution to journalLetter

Secondary Protein Structure
Sequence Homology
Catalytic Domain
Insertional Mutagenesis
Enzymes
17 Citations (Scopus)

Protein structure prediction

Barton, G. J. & Russell, R. B., 11 Feb 1993, In : Nature. 361, 6412, p. 505-506 2 p.

Research output: Contribution to journalLetter

53 Citations (Scopus)

Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites

Matic, I., Ahel, I. & Hay, R. T., Aug 2012, In : Nature Methods. 9, 8, p. 771-772 2 p.

Research output: Contribution to journalLetter

14 Citations (Scopus)

Recessive mutations in the gene encoding frizzled 6 cause twenty nail dystrophy: Expanding the differential diagnosis for pachyonychia congenita

Wilson, N. J., Hansen, C. D., Azkur, D., Kocabas, C. N., Metin, A., Coskun, Z., Schwartz, M. E., Hull, P. R., McLean, W. H. I. & Smith, F. J. D., Apr 2013, In : Journal of Dermatological Science. 70, 1, p. 58-60 3 p.

Research output: Contribution to journalLetter

23 Citations (Scopus)

Reply: A unified classification system for eukaryotic transposable elements should reflect their phylogeny

Wicker, T., Sabot, F., Hua-Van, A., Bennetzen, J. L., Capy, P., Chalhoub, B., Flavell, A., Leroy, P., Morgante, M., Panaud, O., Paux, E., SanMiguel, P. & Schulman, A. H., Apr 2009, In : Nature Reviews Genetics. 10, 4, p. 276 1 p.

Research output: Contribution to journalLetter

Reply to Jiménez-Alonso et al., Schooling and Zhao, and Mortazavi: Further discussion on the immunological model of carcinogenesis

Palmer, S., Albergante, L., Blackburn, C. C. & Newman, T. J., 8 May 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 19, p. E4319-E4321 3 p.

Research output: Contribution to journalLetter

Open Access
3 Citations (Scopus)

Reply to Nakov et al. Model choice requires biological insight when studying the ancestral habitat of photosynthetic eukaryotes

Sánchez-Baracaldo, P., Bianchini, G., Huelsenbeck, J. P., Raven, J. A., Pisani, D. & Knoll, A. H., 12 Dec 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 50, p. E10608-E10609 2 p.

Research output: Contribution to journalLetter

Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing sarcoma

Higgins, E., Capra, M., Schwartz, M. E., Smith, F. J. D., McLean, W. H. I. & Irvine, A. D., Dec 2013, In : British Journal of Dermatology. 169, 6, p. 1357-1360 4 p.

Research output: Contribution to journalLetter

Open Access

Response: Genetic polymorphism of Fc

Woof, J. M., 10 Mar 2006, In : Science. 311, 5766, p. 1377 1 p.

Research output: Contribution to journalLetter

48 Citations (Scopus)

Role of fungi in the biogeochemical fate of depleted uranium

Fomina, M., Charnock, J. M., Hillier, S., Alvarez, R., Livens, F. & Gadd, G. M., 6 May 2008, In : Current Biology. 18, 9, p. R375-R377 3 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Sign-time distribution for a random walker with a drifting boundary

Newman, T. J., 16 Mar 2001, In : Journal of Physics A: Mathematical and General. 34, 10, p. L89-L94 6 p.

Research output: Contribution to journalLetter

Moving Boundary
derivation

Skin fragility, woolly hair syndrome with a desmoplakin mutation – a case from India

Peter, D. C. V., Thomas, M., Wilson, N. J. & Smith, F. J. D., Sep 2018, In : International Journal of Dermatology. 57, 9, p. e73-e75 3 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
124 Downloads (Pure)

Striate palmoplantar keratoderma resulting from a missense mutation in DSG1

Vodo, D., O'Toole, E. A., Malchin, N., Lahav, A., Adir, N., Sarig, O., Green, K., Smith, F. J. D. & Sprecher, E., 17 Sep 2018, In : British Journal of Dermatology. 179, 3, p. 755-757 3 p.

Research output: Contribution to journalLetter

Open Access
File
Palmoplantar Keratoderma
Genetic Databases
Missense Mutation

"The immortal DNA strand" - difficult to digest? Response

Nathke, I., 2 Apr 2010, In : Cell Stem Cell. 6, 4, p. 299-299 1 p.

Research output: Contribution to journalLetter

31 Citations (Scopus)

The iron K feature in narrow line Seyfert 1 galaxies: Evidence for a P Cygni profile?

Done, C., Sobolewska, M. A., Gierliński, M. & Schurch, N. J., 1 Jan 2007, In : Monthly Notices of the Royal Astronomical Society: Letters. 374, 1, p. L15-L19 5 p.

Research output: Contribution to journalLetter

Open Access
ionization
galaxies
iron
profiles
K lines
70 Citations (Scopus)

The limits of protein secondary structure prediction accuracy from multiple sequence alignment

Russell, R. B. & Barton, G. J., 20 Dec 1993, In : Journal of Molecular Biology. 234, 4, p. 951-957 7 p.

Research output: Contribution to journalLetter

Secondary Protein Structure
Sequence Alignment
src Homology Domains
Proteins
Annexins
14 Citations (Scopus)

The role of ATM in response to metformin treatment and activation of AMPK reply

Zhou, K., Bellenguez, C., Sutherland, C., Hardie, G., Palmer, C., Donnelly, P. & Pearson, E., Apr 2012, In : Nature Genetics. 44, 4, p. 361-362 2 p.

Research output: Contribution to journalLetter

25 Citations (Scopus)

The Seyfert AGN RX J0136.9-3510 and the spectral state of super Eddington accretion flows

Jin, C., Done, C., Ward, M., Gierliński, M. & Mullaney, J., Sep 2009, In : Monthly Notices of the Royal Astronomical Society: Letters. 398, 1, p. L16-L20 5 p.

Research output: Contribution to journalLetter

active galactic nuclei
accretion
oscillation
H beta line
x rays
6 Citations (Scopus)
46 Downloads (Pure)

The structure of a Trypanosoma cruzi glucose-6-phosphate dehydrogenase reveals differences from the mammalian enzyme

Mercaldi, G. F., Dawson, A., Hunter, W. N. & Cordeiro, A. T., 19 Aug 2016, In : FEBS Letters. 590, 16, p. 2776-2786 11 p.

Research output: Contribution to journalLetter

Open Access
File
Glucosephosphate Dehydrogenase
Trypanosoma cruzi
NADP
Pentoses
Pentose Phosphate Pathway

Toxin arrest

Stark, M. J. R., 9 Aug 1990, In : Nature. 346, 6284, p. 518-518 1 p.

Research output: Contribution to journalLetter

13 Citations (Scopus)

Triclosan is minimally effective in rodent malaria models

Baschong, W., Wittlin, S., Inglis, K. A., Fairlamb, A. H., Croft, S. L., Kumar, T. R. S., Fidock, D. A. & Brun, R., Jan 2011, In : Nature Medicine. 17, 1, p. 33-34 2 p.

Research output: Contribution to journalLetter

55 Citations (Scopus)
274 Downloads (Pure)

USP7 small-molecule inhibitors interfere with ubiquitin binding

Kategaya, L., Di Lello, P., Rougé, L., Pastor, R., Clark, K. R., Drummond, J., Kleinheinz, T., Lin, E., Upton, J-P., Prakash, S., Heideker, J., McCleland, M., Ritorto, M. S., Alessi, D. R., Trost, M., Bainbridge, T. W., Kwok, M. C. M., Ma, T. P., Stiffler, Z., Brasher, B. & 24 others, Tang, Y., Jaishankar, P., Hearn, B. R., Renslo, A. R., Arkin, M. R., Cohen, F., Yu, K., Peale, F., Gnad, F., Chang, M. T., Klijn, C., Blackwood, E., Martin, S. E., Forrest, W. F., Ernst, J. A., Ndubaku, C., Wang, X., Beresini, M. H., Tsui, V., Schwerdtfeger, C., Blake, R. A., Murray, J., Maurer, T. & Wertz, I. E., 18 Oct 2017, In : Nature. 550, p. 534-538 5 p.

Research output: Contribution to journalLetter

Open Access
File
Ubiquitin-Specific Proteases
Ubiquitin
Magnetic Resonance Spectroscopy
Tumor Suppressor Protein p53
Proteins